Clinical Trials Sponsored by MeiraGTx, LLC

Total 10747 results

MeiraGTx, LLC

Active, not recruiting

A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants

Parkinson Disease

United States
MeiraGTx, LLC

Recruiting

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia (AQUAX2)

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

United States, Canada
MeiraGTx, LLC

Active, not recruiting

Long-Term Follow-Up Study of AAV2hAQP1 for Radiation Induced Xerostomia

Radiation-induced Xerostomia

United States, Canada
MeiraGTx, LLC

Enrolling by invitation

Long-term Follow-up of Glutamic Acid Decarboxylase (GAD) Gene Transfer in Parkinson's Disease

Parkinson Disease

United States
MeiraGTx, LLC
National Institute of Dental and Craniofacial Research (NIDCR)

Active, not recruiting

Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction

Squamous Cell Head and Neck Cancer | Radiation Induced Xerostomia | Salivary Hypofunction

United States
MeiraGTx UK II Ltd

Completed

Clinical Trial of Gene Therapy for the Treatment of Leber Congenital Amaurosis (LCA) (OPTIRPE65)

Leber Congenital Amaurosis

United Kingdom, United States
MeiraGTx UK II Ltd
Janssen Research & Development, LLC

Completed

Gene Therapy for Achromatopsia (CNGA3) (CNGA3)

Achromatopsia

United Kingdom, United States
MeiraGTx UK II Ltd

Completed

A Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia

Head and Neck Cancer | Radiation-Induced Parotid Gland Hypofunction | Xerostomia Due to Radiotherapy

United States, Canada
MeiraGTx UK II Ltd

Completed

Natural History Study of Patients With Leber Congenital Amaurosis Associated With Mutations in RPE65

Leber Congenital Amaurosis

United Kingdom, United States
MeiraGTx UK II Ltd

Completed

Natural History Study for Achromatopsia

Achromatopsia

United Kingdom
MeiraGTx UK II Ltd
Janssen, LP

Active, not recruiting

Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR)

Retinitis Pigmentosa

United States, United Kingdom, Canada
MeiraGTx UK II Ltd
Syne Qua Non Limited

Completed

Long-Term Follow-Up Gene Therapy Study for Leber Congenital Amaurosis OPTIRPE65 (Retinal Dystrophy Associated With Defects in RPE65)

Eye Diseases | Retinal Diseases | Eye Diseases, Hereditary | Leber Congenital Amaurosis (LCA)

United States, United Kingdom
MeiraGTx UK II Ltd
Syne Qua Non Limited; EMAS Pharma

Completed

Gene Therapy for Achromatopsia (CNGB3) (CNGB3)

Achromatopsia

United Kingdom, United States
MeiraGTx UK II Ltd
Syne Qua Non Limited; EMAS Pharma

Completed

Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3

Achromatopsia

United Kingdom, United States
MeiraGTx UK II Ltd
Syne Qua Non Limited; Bionical Emas

Completed

Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)

X-Linked Retinitis Pigmentosa

United Kingdom, United States
Arthritis Northwest PLLC
Epigenesys LLC

Unknown

Identification of Epigenetic Biomarkers for Early Detection of Rheumatic Disease

Arthritis, Rheumatoid

United States
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
Synochi, LLC
LAC+USC Medical Center

Not yet recruiting

Prospective Placebo-controlled Study of Synochi Scar Spray

Burns Multiple
LLS PedAL Initiative, LLC
Kura Oncology

Not yet recruiting

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

Relapsed/Refractory KMT2A-r Acute Leukemia | Relapsed/Refractory NUP98-r Acute Leukemia | Relapsed/Refractory NPM1-m Acute Leukemia
Derm Research, PLLC
WFH MEDICAL, LLC

Completed

Aczone 5% Gel as Maintenance Treatment of Acne Vulgaris Following Completion of Oral Doxycycline and Aczone 5% Gel

Acne Vulgaris

United States
Verily Life Sciences LLC
The Emmes Company, LLC; Optos, PLC; Google LLC.; Nikon Corporation

Completed

ARDA Software for the Detection of mtmDR

Diabetic Retinopathy

United States
MedRegen LLC
Johns Hopkins University; ICON plc

Recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients

COVID-19 | ARDS, Human | Regeneration | Stem Cells

United States
Redx Pharma Plc
Merck Sharp & Dohme LLC

Completed

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (KEYNOTE-E86)

Advanced Solid Tumours

United Kingdom, Australia
4D pharma plc
Merck Sharp & Dohme LLC

Terminated

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Oncology

United States
IVFarma LLC
BridgePharm LLC; GlobalPharma LLC

Completed

Study to Compare Efficacy and Safety of Primapur and Gonal-f in Women for Assisted Reproductive Treatment

Infertility, Female

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Not yet recruiting

Bioequivalence Study of Two Formulations of Etoricoxib Tablets 120 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Not yet recruiting

Bioequivalence Study of Two Formulations of Rivaroxaban Tablets 20 mg in Healthy Male Volunteers Under Fed Conditions

Bioequivalence

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Atorvastatin Film-coated Tablets 40 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Clopidogrel Film-coated Tablets 75 mg in Healthy Male Subjects Under Fasting Conditions

Bioequivalence

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Clavamox, Film-coated Tablets, 875 mg + 125 mg Pharmtechnology LLC, Belarus), and Augmentin®, Film-coated Tablets, 875 mg + 125 mg (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Clavamox, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (Pharmtechnology LLC, Belarus), and Augmentin®, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Not yet recruiting

Bioequivalence Study of Two Formulations of Sildenafil Tablet 100 mg in Healthy Male Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
IVFarma LLC
NADIM LLC

Completed

The Safety and Pharmacokinetics of Primapur and Gonal-f

Pharmacokinetics | Absorption | Area Under Curve

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Montelukast, 5 mg Chewable Tablets (Pharmtechnology LLC, Belarus), and Singulair®, 5 mg Chewable Tablets (Merck Sharp & Dohme B.V., the Netherlands), in Healthy Volunteers Under Fasting Conditions

Healthy Adults

Russian Federation
Immunitor LLC
Ekomed LLC

Unknown

Open Label Immunotherapy of Endometriosis

Endometriosis

Mongolia
Monsoon Design Studio LLC
Healthark Wellness Solutions LLP

Completed

Study of Evoked Emotional Responses

Emotion, Expressed

India
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Torasemide Tablet 10 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
AOBiome LLC
bioRASI, LLC

Completed

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

Atopic Dermatitis

United States
AOBiome LLC
bioRASI, LLC

Completed

A Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Rosacea

Rosacea

United States
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Lisinopril Tablet 20 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
BioMendics, LLC
Symbio, LLC

Completed

Efficacy of Topical TolaSure on Acute Induced Wounds in Healthy Participants

Wound Healing

United States
Pharmtechnology LLC
ClinPharmInvest, LLC

Unknown

Bioequivalence Study of Two Formulations of Rivaroxaban Tablets 10 mg in Healthy Male Volunteers in Fasting Conditions

Bioequivalence

Russian Federation
Soniphi LLC
UserWise, LLC

Unknown

Vocal Feature Analysis Algorithm for COVID-19 Detection

COVID-19

United States
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

A Bioequivalence Study of Two Formulations Lamotrigine 100 mg Tablets and Lamictal 100 mg Tablets in Healthy Adult Volunteers Under Fasting Conditions

Healthy Adults

Russian Federation
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Ibuprofen D, Oral Suspension, 200 mg/5ml and Nurofen®, Oral Suspension 100 mg/5 ml in Healthy Volunteers Under Fasting Conditions

Healthy

Russian Federation
Cristcot LLC
Cristcot HCA LLC

Recruiting

Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

Ulcerative Proctitis

United States, Georgia, Denmark, South Africa, Vietnam, Lebanon, Jordan, Saudi Arabia, Philippines, Poland, France, India, Romania, Bulgaria, Moldova, Republic of, Turkey
Pharmtechnology LLC
Ligand Research, LLC

Completed

Bioequivalence Study of Two Formulations of Tablets Ramipril/Hydrochlorothiazide 10 mg/25 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
PHARMENTERPRISES LLC
RSV Therapeutics LLC

Completed

Study to Assess Efficacy and Safety of XC221 200 mg in the Treatment of Influenza or Other ARVI

Influenza | Acute Respiratory Viral Infections

Russian Federation
Nearmedic Plus LLC
OCT LLC

Completed

Phase 1 Study of PBTZ169

Tuberculosis
Amneal Pharmaceuticals, LLC
Symbio, LLC

Completed

Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)

Uncomplicated Urinary Tract Infections

United States

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