Clinical Trials Sponsored by Modern Biosciences plc

Total 88 results

Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Modern Biosciences Ltd

Completed

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA

Rheumatoid Arthritis

Bosnia and Herzegovina, Bulgaria, Chile, Czechia, Guatemala, Mexico, Poland, Serbia
Modern Biosciences Ltd

Recruiting

A Study to Investigate Leramistat in Patients With IPF

Idiopathic Pulmonary Fibrosis

United States, United Kingdom, Israel, France, Germany, Greece, Hungary, Italy, Spain
Modern Biosciences Ltd

Completed

Safety, Tolerability and Efficacy of MBS2320 in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Georgia, Moldova, Republic of, Romania
Modern Biosciences Ltd
Covance

Completed

Safety and Tolerability Study of MBS2320 in Healthy Subjects and Subjects With Rheumatoid Arthritis

Arthritis, Rheumatoid

United Kingdom
Harmony Biosciences, LLC

Recruiting

WAKIX® (Pitolisant) Pregnancy Registry

Pregnancy Related | Narcolepsy

United States
Harmony Biosciences, LLC

Active, not recruiting

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Myotonic Dystrophy 1 | Excessive Daytime Sleepiness

United States, Canada
Kashiv BioSciences, LLC

Completed

To Compare the PK, PD, Safety & Immunogenicity of ADL-018 in Healthy Subjects

Healthy

India
Palladio Biosciences
Centessa Pharmaceuticals plc

Terminated

Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease (ACTION)

Autosomal Dominant Polycystic Kidney | ADPKD

United States, Spain, Hungary, United Kingdom, Australia, Bulgaria, Poland, Turkey
Harmony Biosciences, LLC

Recruiting

A Study of Pitolisant in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Kashiv BioSciences, LLC

Recruiting

PK, PD, Safety & Immunogenicity of ADL-018 Lyo in Healthy Adult Subjects

Healthy

India
Kashiv BioSciences, LLC

Completed

Open Label, Sequential Dosing , Single Ascending Dose and Multiple Dose Safety Tolerability and Pharmacokinetic Study

Metastatic Breast Cancer

Jordan
Harmony Biosciences, LLC

Active, not recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

Prader-Willi Syndrome

United States
Whitecap Biosciences, LLC

Completed

Safety and IOP-Lowering Effects of WB007

Ocular Hypertension | Glaucoma, Primary Open Angle

United States
Harmony Biosciences, LLC

No longer available

Expanded Access Program to Provide Treatment With Pitolisant to Adult Patients in the U.S. With Excessive Daytime Sleepiness Associated With Narcolepsy With or Without Cataplexy

Narcolepsy Without Cataplexy | Narcolepsy With Cataplexy

United States
Conceptra Biosciences, LLC

Recruiting

CCT-102 vs. Expectant Management in Delayed Pregnancy Loss (MERMAID)

Early Pregnancy Loss, Delayed Pregnancy Loss

United States
Akan Biosciences, LLC

Not yet recruiting

Safety and Tolerability of StroMel™ in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint

Osteo Arthritis Knee

United States
Harmony Biosciences, LLC

Completed

A Phase 3 Study to Assess the Safety and Efficacy of Pitolisant in Adult Patients With Idiopathic Hypersomnia

Idiopathic Hypersomnia

United States
Harmony Biosciences, LLC

Active, not recruiting

A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia

Idiopathic Hypersomnia | Excessive Daytime Sleepiness

United States
Kaligia Biosciences, LLC

Unknown

A Human Clinical Study to Collect Calibration and Performance Data for the RBA-1 and KBS-1

Calibration and Validation of Analyte Testing System

United States
Palladio Biosciences
Centessa Pharmaceuticals plc

Terminated

Roll-over Study to Assess Safety of Lixivaptan in Participants With ADPKD Who Completed Study PA-ADPKD-303

Polycystic Kidney Disease, Adult

United States
Palladio Biosciences
Centessa Pharmaceuticals plc

Terminated

Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease (ALERT)

ADPKD | Polycystic Kidney Disease, Adult

United States
Equilibra Bioscience LLC

Recruiting

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)

Hemophilia A | Hemophilia B | Healthy Participants

United States
Castle Creek Biosciences, LLC.

Withdrawn

Pilot Safety and Efficacy Study of Isolagen Therapy in Treatment of Restrictive Burn Scars

Restrictive Burn Scars of Joint Area

United States
HealthBeacon Plc
Modena Allergy & Asthma

Enrolling by invitation

A Pilot Study to Assess the Suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) Device

Respiratory Disease

United States
Sidero Bioscience, LLC

Completed

BioFe, Medical Food for the Dietary Management of Iron Deficiency

Iron Deficiency

United States
Trellis Bioscience LLC

Not yet recruiting

Study to Evaluate Safety and Activity of TRL1068 in Chronic Rhinosinusitis

Chronic Rhinosinusitis With Nasal Polyps
Castle Creek Biosciences, LLC.

Completed

Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia

Dysphonia Resulting From Vocal Fold Scarring | Age-related Dysphonia

United States
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring

Acne Scarring of the Face

United States
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Isolagen TherapyTM in the Treatment of Nasolabial Fold Wrinkles

Bilateral Nasolabial Fold Wrinkles

United States
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Isolagen Therapy in the Treatment of Nasolabial Fold Wrinkles

Bilateral Nasolabial Fold Wrinkles

United States
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Facial Wrinkles and Creases

Facial Wrinkles and Creases

United States
Castle Creek Biosciences, LLC.

Active, not recruiting

A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa (DEFI-RDEB)

Recessive Dystrophic Epidermolysis Bullosa

United States
Castle Creek Biosciences, LLC.

Terminated

A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Scleroderma, Localized | Morphea | Scleroderma

United States
Castle Creek Biosciences, LLC.

Terminated

A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Epidermolysis Bullosa Dystrophica, Recessive

United States
Castle Creek Biosciences, LLC.

Terminated

Pilot Study of Azficel-T for the Treatment of Restrictive Burn Scars

Restrictive Burn Scars

United States
Castle Creek Biosciences, LLC.

Completed

Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Interdental Papillary Insufficiency

Interdental Papillary Insufficiency

United States
Diabetes and Glandular Disease Clinic
Modern Vascular, LLC

Unknown

Exploratory Study of the Efficacy of Standard of Care Revascularization of the Lower Extremity

Diabetic Peripheral Neuropathy

United States
Merck Sharp & Dohme LLC
Moderna TX

Recruiting

A Study of (Neo)Adjuvant V940 and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007)

Carcinoma, Squamous Cell | Skin Neoplasms

Chile, Australia, Israel, New Zealand
Capella Bioscience Ltd
Centessa Pharmaceuticals plc

Terminated

Study of Intravenously Administered Anti-LIGHT Monoclonal Antibody CBS001 in Healthy Volunteers

Chronic Inflammatory Disease

United Kingdom
CeloNova BioSciences, Inc.
ClinLogix. LLC

Terminated

COBRA SHIELD OCT Study

Stable Angina

Finland
Presage Biosciences
Merck Sharp & Dohme LLC

Recruiting

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Solid Tumor

United States
Presage Biosciences
Merck Sharp & Dohme LLC

Completed

PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS

Soft Tissue Sarcoma | Head and Neck Squamous Cell Carcinoma

United States
Qure Healthcare, LLC
Venn Biosciences Corporation

Withdrawn

Establishing Clinical Utility Evidence to Support Coverage and Reimbursement for Venn Biosciences' Dawn Test

Non Small Cell Lung Cancer
Shanghai Best-Link Bioscience, LLC

Recruiting

A Phase I Study to Assess the Safety and Tolerability of BL0006 for Patients With Advanced Solid Tumours

Advanced Solid Tumor

China
Loughborough University
entrinsic bioscience LLC

Active, not recruiting

A Comparison of Three Commercial Oral Rehydration Solutions Consumed After Extra-cellular Dehydration

Fluid Balance Outcomes

United Kingdom
Shanghai Best-Link Bioscience, LLC

Recruiting

Phase I Study of BL0020, a Novel Anti-tumor Drug, in Adult Subjects With Advanced Solid Tumors

Advanced Solid Tumor

China, Australia
Evopoint Biosciences Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)

Carcinoma | Cervical Cancer | Prostate Cancer | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Other Solid Tumors

China
Kaligia Biosciences, LLC
University of South Florida

Unknown

A Human Clinical Study to Collect Calibration and Performance Data for the RBA-2 Device

COVID | Coronavirus

United States
Coherus Biosciences, Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Clear Cell Renal Cell Carcinoma | Hepatocellular Carcinoma | Advanced Solid Tumor | Non-small Cell Lung Cancer

Korea, Republic of, United States, Singapore

Clinical Trials Sponsored by Modern Biosciences plc

Sponsors and Collaborators

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CROs in Serbia

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