Clinical Trials Sponsored by Mononuclear Therapeutics Ltd.

Total 445 results

Melinta Therapeutics, Inc.
Christchurch Clinical Studies Trust Ltd

Completed

Oritavancin on the Results of Multiple Coagulation Tests in Healthy Volunteers

Healthy Volunteers

New Zealand
Shanghai PerHum Therapeutics Co., Ltd.
Shanghai Zhongshan Hospital

Active, not recruiting

A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors (CAR)

Soft Tissue Sarcoma | Gastric Cancer | Pancreatic Cancer | Solid Tumor | Bladder Cancer

China
Spero Therapeutics
CPR Pharma Services Pty Ltd, Australia

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR741 in Healthy Volunteers

Healthy Volunteers

Australia
Hebrew University of Jerusalem
Anchiano Therapeutics Israel Ltd.

Completed

Safety and Proof of Concept Study of Intravesical DTA-H19 in Patients With Superficial Bladder Cancer

Bladder Neoplasms

Israel
MediLink Therapeutics (Suzhou) Co., Ltd.
Hoffmann-La Roche

Not yet recruiting

A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Asia Cell Therapeutics (Shanghai) Co., Ltd.
RenJi Hospital

Not yet recruiting

Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis
Carmot Australia First Pty Ltd
Carmot Therapeutics, Inc.

Recruiting

Phase 1 Study of CT-996 in Overweight/Obese Participants and Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes | Overweight or Obesity

Australia
Zhejiang University
Hangzhou Cheetah Cell Therapeutics Co., Ltd

Recruiting

NKG2D CAR-NK & r/rAML

AML

China
Shanghai PerHum Therapeutics Co., Ltd.
Shanghai Zhongshan Hospital

Recruiting

CCT301-38 CAR-T in Patients With Relapsed or Refractory AXL Positive Sarcomas

SAR

China
Carmot Therapeutics, Inc.
Carmot Australia First Pty Ltd

Recruiting

A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus

Diabetes

Australia, Mexico
Suzhou Transcenta Therapeutics Co., Ltd.
Bristol-Myers Squibb

Recruiting

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

Gastric Cancer | Pancreatic Cancer | Advanced Cancer | Gastroesophageal-junction Cancer

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.
G1 Therapeutics, Inc.

Completed

Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world Study

Extensive-stage Small-cell Lung Cancer

China
Impatients N.V. trading as myTomorrows
Immodulon Therapeutics Ltd

No longer available

Expanded Access Program Using IMM-101 for Patients With Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Cancer Stage IV | Pancreas Cancer | Pancreatic Cancer Stage III

France, United Kingdom
Spero Therapeutics
CPR Pharma Services Pty Ltd, Australia

Completed

Phase 1 Study of Safety, Tolerability and Pharmacokinetics of SPR994

Healthy Volunteers

Australia
Aminex Therapeutics, Inc.
Iqvia Pty Ltd; Novella Clinical

Withdrawn

Study of Orally-Administered AMXT 1501 Dicaprate in Normal Healthy Volunteers

Neoplasms | Tolerance | Medication Toxicity

United States
OcuCure Therapeutics, Inc.
Semler Research Center Pvt. Ltd.

Terminated

A Study Assessing Efficacy and Safety of OC-10X in the Treatment of PDR

Proliferative Diabetic Retinopathy (PDR)

Bangladesh
Enlivex Therapeutics Ltd.
Nordic Bioscience Clinical Development (NBCD)

Recruiting

Study of Intra-articular Allocetra in Knee Osteoarthritis

Osteoarthritis, Knee

Israel
Amir Oron
Enlivex Therapeutics Ltd.

Recruiting

Use of Allocetra-OTS in End Stage Knee Osteoarthritis - Assessment of Safety

Knee Osteoarthritis

Israel
Carbiogene Therapeutics Co. Ltd.
Zhejiang Provincial People's Hospital

Recruiting

Clinical Study of Anti-ILT3 CAR-T Therapy for R/R AML(M4/M5)

AML M5 | AML M4

China
Xinqiao Hospital of Chongqing
Carbiogene Therapeutics Co. Ltd.

Recruiting

Anti-BCMA CAR-T Cell Therapy for the R/R Multiple Myeloma

Multiple Myeloma

China
Shanghai PerHum Therapeutics Co., Ltd.
Shanghai Zhongshan Hospital

Recruiting

A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors

Sarcoma | Breast Cancer | Gastric Cancer | Ovarian Cancer | Solid Tumor

China
Suzhou Transcenta Therapeutics Co., Ltd.
Bristol-Myers Squibb

Recruiting

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors

Advanced Cancer

China
Jiangsu Simcere Pharmaceutical Co., Ltd.
G1 Therapeutics, Inc.

Completed

Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Extensive-Stage Small Cell Lung Cancer Patients Receiving Carboplatin Combined With Etoposide or Topotecan

Extensive-stage Small-cell Lung Cancer

China
Spero Therapeutics
Clinical Network Services (CNS) Pty Ltd

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR206 in Healthy Volunteers

Healthy Volunteers

Australia
First Affiliated Hospital Xi'an Jiaotong University
Eureka Therapeutics Inc.; Aeon Therapeutics (Shanghai) Co., Ltd.

Completed

ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma

Liver Neoplasms | Hepatocellular Carcinoma | Liver Cancer | Metastatic Liver Cancer

China
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Recruiting

Clinical Trail of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021) in Participants Aged 18 Years and Older

SARS-CoV-2

Pakistan
AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Not yet recruiting

Clinical Study of SARS-CoV-2 Variant mRNA Vaccine in Healthy Participants

SARS-CoV-2
Zai Lab (Shanghai) Co., Ltd.
Mirati Therapeutics Inc.

Active, not recruiting

The Clinical Trial to Evaluate the Pharmacokinetics and Safety of MRTX849 in Patients With Advanced Solid Tumors

Advanced or Metastatic Solid Tumor

China
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Recruiting

Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia

Eye Diseases | Presbyopia | Miosis | Near Vision

China
AIO-Studien-gGmbH
Roche Pharma AG; Immodulon Therapeutics Ltd

Recruiting

Atezolizumab in Patients With MSI-h/MMR-D Stage III Colorectal Cancer Ineligible for Oxaliplatin (ANTONIO)

Colorectal Cancer

Germany
Innovative Cellular Therapeutics Co., Ltd.
Anhui Provincial Cancer Hospital

Not yet recruiting

CART Therapy in Digestive System Tumors

Malignant Neoplasms of Digestive Organs

China
Weill Medical College of Cornell University
NeoTX Therapeutics Ltd.

Withdrawn

Naptumomab Estafenatox in Combination With Pembrolizumab Preceded by Obinutuzumab in Patients With Urothelial Cancers

Urothelial Carcinoma

United States
Zhejiang Provincial People's Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Completed

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Carcinoma

China
F-star Therapeutics, Inc.
CSI Medical Research Pte Ltd

Terminated

Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients

Hepatitis B | Hepatitis B, Chronic | HBV

Singapore
Horizon Therapeutics, LLC

Completed

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Urea Cycle Disorders

United States, Canada
BioSync Scientific Pvt. Ltd.
Cardialysis BV; MIV Therapeutics Inc.

Unknown

Hydroxyapatite Active Pro Healing Clinical Trial Program (HApFIM)

Coronary Artery Disease
Changzhou No.2 People's Hospital
Rui Therapeutics Co., Ltd

Not yet recruiting

An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia

Thrombocytopenia Alloimmune
Children's Hospital of Fudan University
CorrectSequence Therapeutics Co., Ltd

Recruiting

Base-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia Major

Beta-Thalassemia

China
Zhejiang Provincial People's Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Personalized Neoantigen Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Resectable Pancreatic Cancer

China
Turning Point Therapeutics, Inc.
Zai Lab (Shanghai) Co., Ltd.

Recruiting

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)

Locally Advanced Solid Tumors | Metastatic Solid Tumors

United States, China, Japan, Australia, Belgium, Canada, Denmark, France, Germany, Hong Kong, Hungary, Italy, Korea, Democratic People's Republic of, Korea, Republic of, Netherlands, Poland, Singapore, Spain, Taiwan, United Kingdom
Five Prime Therapeutics, Inc.
Zai Lab (Shanghai) Co., Ltd.

Completed

A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer (FIGHT)

Gastric Cancer

United States, Spain, China, Italy, Korea, Republic of, Portugal, Taiwan, Japan, Turkey, France, Hungary, Thailand, Germany, Poland, Australia, Belgium, Romania, United Kingdom
Base Therapeutics (Shanghai) Co., Ltd.
Shanghai 10th People's Hospital

Enrolling by invitation

Safety and Efficacy of NK510 to Treat Gastric Cancer

Gastric Cancer

China
Horizon Therapeutics, LLC

Completed

Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs)

Urea Cycle Disorder

United States, Spain, Italy, Switzerland
Paracrine Therapeutics Dermatology Pte. Ltd.
National University Hospital, Singapore

Completed

Safety and Tolerability Study of MSC Exosome Ointment

Psoriasis

Singapore
Imperial College London
Medical Research Council; Atopix Therapeutics, Ltd.

Completed

Effect of OC459 on the Response to Rhinovirus Challenge in Asthma

Picornaviridae Infections | Asthma | Common Cold | Rhinovirus

United Kingdom
Landmark Medical Centre Sdn Bhd
CytoMed Therapeutics Pte Ltd

Unknown

MSC Infusion for Anti-aging and Regenerative Therapy (REGEN)

Aging Well | Regenerative Medicine

Malaysia
ACEA Therapeutics, Inc.
Hangzhou ACEA Pharmaceutical Research Co., Ltd.

Unknown

Study of AC0058TA in Patients With Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

United States
Changhai Hospital
Shanghai Ultra-T Immune Therapeutics Co. LTD

Not yet recruiting

A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System

Digestive Tumor
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

Presbyopia

China
Enlivex Therapeutics Ltd.
Cato Research; Accelsiors CRO & Consultancy Services

Active, not recruiting

A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients

Sepsis | Intraabdominal Infections | Cholecystitis, Acute | Urinary Tract Infections | Community-acquired Pneumonia | Cholangitis Acute

Netherlands, Israel, France, Belgium, Spain

Clinical Trials Sponsored by Mononuclear Therapeutics Ltd.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Switzerland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations