Clinical Trials Sponsored by National Medical Research Council (NMRC), Singapore

Total 452 results

National University, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study (SINGER)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Cognitive Impairment | Dementia | Alzheimer Disease | Cognition Disorder | Vascular Cognitive Impairment

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Sirolimus Drug-coated Balloon Versus Stent Graft (SUSTAIN)

Blood Vessel Prosthesis | Arteriovenous Shunt Thrombosis

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Evaluating a Novel Individualised Treatment Strategy for Carbapenem-Resistant Gram-Negative Bacteria Infections

Antibiotic Therapy

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Completed

COmbiNing Cutting and Drug-Eluting Balloon for Resistant Arteriovenous Fistula sTenOsis (CONCERTO) (CONCERTO)

Arteriovenous Fistula Stenosis

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Unknown

Effects of Fenofibrate Therapy in Diabetic Nephropathy

Diabetes Mellitus | Diabetic Nephropathies

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Unknown

Impact of Preoperative Anemia on Healthcare Outcomes

Anemia

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Completed

Prospective Randomized Trial Comparing DEB Versus Conventional PTA for the Treatment of Hemodialysis AVF or AVG Stenoses (DEBAPTA)

Stenosis of Arteriovenous Dialysis Fistula | Arteriovenous Graft Stenosis

Singapore
Singapore Eye Research Institute
National Medical Research Council (NMRC), Singapore

Unknown

The Asia Primary Tube Versus Trab (TVT) Study (TVT)

Glaucoma

Singapore
National University of Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Urban Care Farming on Living Well and Productive Engagement of Older Adults

Stress, Psychological

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients

Metastatic Pancreatic Cancer

Singapore
National Heart Centre Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Evaluating DyNamic Myocardial Blood Flow QUantitation As a Cost Effective Care ModeL for DiabEtic Patients With Coronary Artery DiSease (NUCLEuS)

Coronary Artery Disease | Diabetes Mellitus

Singapore
Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore

Active, not recruiting

The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)

Myopia

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Impact of Measures Taken to Contain COVID-19 on Hospital Surgical Care Services and Clinical Outcomes

Surgery

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Unknown

Dietary Intervention in Diabetes Mellitus (DIDM)- Intermediate and Acute Effects (DIDM)

Type 2 Diabetes Mellitus

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Unknown

Comparison Between Probe-based Confocal Laser Endomicroscopy, White-light Endoscopy and Virtual Chromoendoscopy (pCLE-GCEP)

Intestinal Metaplasia | Intestinal Dysplasia

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Unknown

Metabolic Effects of Birth Weight on Overweight and Obese Chinese Adults and Their Responses to Weight Loss (SAMS-2)

Healthy | Obesity | Overweight

Singapore
Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore

Unknown

Asymptomatic Narrow Angles - Laser Iridotomy Study; Multicentric RCT

Asymptomatic Narrow Angles | Primary Angle Closure Suspects

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Unknown

Using Telerehabilitation Tools to Deliver Quality Therapy to Patients Under Infective Isolation Precautions (IsoRehab2018)

Deconditioning, Isolation Precautions
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Completed

Autologous Cytokine-induced Killer Cell Adoptive Immunotherapy for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Myelodysplastic Syndrome, High Grade

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Completed

Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies (alloCIK)

Acute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Non Hodgkin's Lymphoma | Hodgkin's Disease

Singapore
National Heart Centre Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Role of ARNi in Ventricular Remodeling in Hypertensive LVH (REVERSE-LVH)

Hypertensive Heart Disease

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Active, not recruiting

Dose-determining and Dose-confirmatory Study to Investigate the Optimal Dose of Tamoxifen in Breast Cancer Patients According to Genotype Status of TCF20 rs932376

Breast Cancer

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Unknown

HOPE (Healthy Older People Everyday) To Age in Place

Frail Elderly Syndrome
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Combined Use of BCG and Interferon Alpha in Bladder Cancer

Carcinoma of Urinary Bladder, Superficial

Singapore
National Dental Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures

Partial-edentulism

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

The Role of Bexarotene in Inducing Susceptibility to Chemotherapy in Metastatic TNBC

Metastatic Triple-Negative Breast Carcinoma

Singapore
National University of Singapore
National Medical Research Council (NMRC), Singapore

Completed

Diabetes Risk Communication Tool Evaluation

Type 2 Diabetes

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Completed

OXIRI [Oxaliplatin (O), Xeloda (X) and Irinotecan (I)] in Pancreatic Adenocarcinoma (OXIRI)

Pancreatic Cancer

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Mini Versus Conventional Cardiopulmonary Bypass In CABG in Asian Patients (MiniCPB)

Acute Kidney Injury | Neurological Injury

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Autologous Cord Blood Cells for Brain Injury in Term Newborns

Hypoxic Ischemic Encephalopathy

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Unknown

To Investigate the Influence of Ethnicity in Metabolic Disease in Healthy, Overweight and Obese Subjects (SAMS-1)

Healthy | Obesity | Overweight

Singapore
CHIMES Society
National Medical Research Council (NMRC), Singapore

Completed

CHInese Medicine NeuroAid Efficacy on Stroke Recovery (CHIMES)

Stroke | Cerebral Infarction

Philippines, Thailand, Singapore, Hong Kong, Malaysia, Sri Lanka
National University Hospital, Singapore
National University, Singapore; National Medical Research Council (NMRC), Singapore

Completed

Study of New Biological Markers for Prediction of Severe Acute Pancreatitis

Acute Pancreatitis

Singapore
Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore; Singapore Eye Research...

Completed

Comparing Phaco/IOL Versus Phaco/IOL + Goniosynechialysis in Subjects With PACG

Glaucoma, Angle-closure

Singapore
Singapore General Hospital
National Heart Centre Singapore; National Medical Research Council (NMRC),...

Completed

Acute Chest Pain Treatment and Evaluation (ACTION) Study

Chest Pain

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore; Sengkang Health

Unknown

Comparing Proposed Algorithm and Current Practice in the Evaluation of Suspected Appendicitis (RCTAppAlg)

Acute Appendicitis

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; National University of...

Unknown

Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells (CTC)

Cancer

Singapore
National Medical Research Council (NMRC), Singapore

Completed

Megestrol in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery

Liver Cancer

Singapore, Bangladesh, Thailand, Vietnam, Philippines, Indonesia, Korea, Republic of, Myanmar, New Zealand, Taiwan
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; ASLAN Pharmaceuticals

Active, not recruiting

ASLAN001 in Combination With Oxaliplatin and Capecitabine or Oxaliplatin and 5-FU With Leucovorin

Solid Tumors

Singapore
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore; National University of...

Not yet recruiting

DREAMS-OT Trial: Delirium Reduction Through Early Activation in Motivating and Sleep Promoting Routines: A Randomized Controlled Trial of Occupational Therapy for ICU Patients After Coronary Artery Bypass Graft (CABG) Surgery (DREAMS-OT)

Delirium, Postoperative
National University of Singapore
National Skin Centre, Singapore; National Medical Research Council (NMRC),...

Completed

STI/HIV Prevention Intervention for Adolescents in Singapore

Sexually Transmitted Infections
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore; National University of...

Completed

Influence of Probiotics on Prevention of Atopy, Atopic Disease and Immunological Responses

Asthma | Allergic Rhinitis | Eczema

Singapore
National Medical Research Council (NMRC), Singapore

Unknown

Radioactive Iodine in Treating Patients Who Have Undergone Surgery for Liver Cancer

Liver Cancer

Singapore
National Medical Research Council (NMRC), Singapore

Unknown

Comparison of Two Types of Surgery in Treating Patients With Rectal Cancer

Colorectal Cancer

China, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Tamoxifen in Treating Patients With Primary Liver Cancer

Liver Cancer

New Zealand, Hong Kong, Indonesia, Malaysia, Pakistan, Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; Ministry of Health, Singapore

Active, not recruiting

ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore (ENABLE-HF-SG)

Heart Failure

Singapore
Khoo Teck Puat Hospital
National Medical Research Council (NMRC), Singapore

Completed

Effects of High-Dose Resveratrol in Non-Diabetic Obese Males

Obesity | Diabetes

Singapore
National University Health System, Singapore
National University Hospital, Singapore; National Medical Research Council...

Completed

Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy (DPN-QoL)

Diabetic Neuropathies | Peripheral Nervous System Diseases

Singapore
Tan Tock Seng Hospital
National Medical Research Council (NMRC), Singapore

Completed

Refinement and Clinical Evaluation of the H-Man for Arm Rehabilitation After Stroke

Stroke

Singapore
Medicine
Janssen Pharmaceuticals; National Medical Research Council (NMRC), Singapore

Unknown

Assessing Progression to Type-2 Diabetes (APT-2D): A Prospective Cohort Study Expanded From BRITE-SPOT (Bio-bank and Registry for StratIfication and Targeted intErventions in the Spectrum Of Type 2 Diabetes) (APT-2D)

Diabetes | Pre-diabetes

Singapore

Clinical Trials Sponsored by National Medical Research Council (NMRC), Singapore

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