Clinical Trials Sponsored by Nuvance Health

Total 50369 results

R-Pharm
Covance; Cromos Pharma LLC

Withdrawn

Study of the Efficacy and Safety of a Single Administration of Olokizumab vs. Placebo in Addition to Standard Treatment in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19).

COVID-19
Hill Dermaceuticals, Inc.
Covance; Synteract, Inc.

Terminated

Clobetasol Topical Oil for Children With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
GlaxoSmithKline
Hammersmith Medicines Research; Covance Harrogate

Completed

A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects

Hypertension, Pulmonary

United Kingdom
GE Healthcare
Covance; H2O Clinical LLC

Completed

Re-Read Study to Compare the Brain Uptake of [18F]Flutemetamol With Brain Neuritic Plaque Density Determined Postmortem

Cognitive Impairment

United States
AstraZeneca
Covance; ICON plc; PHT Corporation

Terminated

Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Nuance Pharma (shanghai) Co., Ltd
Laboratory Corporation of America

Recruiting

A Study to Evaluate the Efficacy and Safety of Ensifentrine for 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

China
Vance Thompson Vision - MT

Not yet recruiting

IIT Assessing OC-01Nasal Spray on Symptoms of DED Following CXL

Dry Eye Disease

United States
Actelion
Henry Ford Health System; Covance; Medidata Solutions; Almac Clinical Technologies and other collaborators

Terminated

An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients. (RUBATO OL)

Congenital Heart Disease With Fontan Circulation

United Kingdom, Taiwan, France, Poland, China, Australia, Czechia, Canada, United States, Denmark, New Zealand
Velindre NHS Trust
AstraZeneca; Cardiff and Vale University Health Board; Covance; Cenduit LLC

Active, not recruiting

Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer (FAKTION)

Estrogen Receptor Positive Breast Cancer

United Kingdom
Global Health Drug Discovery Institute
CMAX Clinical Research Pty Limited; Avance Clinical

Completed

SAD Study of APR002 Investigating the Safety/Tolerability, Pharmacokinetics/Pharmacodynamics in Healthy Subjects

COVID-19

Australia
Vance Thompson Vision ND

Completed

Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Laser-assisted in Situ Keratomileusis (LASIK)

Dry Eye Disease

United States
Vance Thompson Vision ND

Unknown

Outcomes of a Trifocal IOL in Post-refractive Patients (TrIPLe)

Refractive Errors

United States
Vance Thompson Vision - MT

Unknown

The PRIME Study: A Randomized, Controlled, Prospective Study

Patient Preference | Post-Operative Inflammation | Patient Outcomes | Grade of Post-Operative Cystoid Macular Edema | Rate of Post-Operative Cystoid Macular Edema

United States
Eisai Inc.
PPD; Covance; Quest Pharmaceutical Services

Terminated

A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Elderly Patients Undergoing Elective Colonoscopy

Colonoscopy | Colon Polyps
Altavant Sciences GmbH
Covance; Altavant Sciences, Inc.

Completed

Pharmacokinetics and Excretion of Oral [14C]-Rodatristat Ethyl

Healthy

United States
Eisai Inc.
PPD; Covance; Quest Pharmaceutical Services

Terminated

A Study of AQUAVAN® Injection for Sedation in Elderly Patients Undergoing Flexible Bronchoscopy

Flexible Bronchoscopy
AstraZeneca
Takeda; Covance; Catalent; MMS Holdings, Inc

Completed

Single Ascending Dose Study of MEDI1341 in Healthy Volunteers

Parkinson's Disease

United States
Imperial College London
Medical Research Council; Covance

Completed

Study of the Gut Hormone Analogue G3215 in Adult Subjects

Obesity | Diabetes Mellitus

United Kingdom
AstraZeneca
PPD; Parexel; Covance; Iqvia Pty Ltd

Completed

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma (TATE)

Severe Uncontrolled Asthma

United States, Japan
Roswell Park Cancer Institute
Iovance Biotherapeutics, Inc.

Withdrawn

Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Unresectable Renal Pelvis Urothelial Carcinoma | Unresectable Ureter Urothelial Carcinoma

United States
R-Pharm
Covance; Boryung Pharmaceutical Co., Ltd

Completed

Efficacy and Safety Evaluating Study to Compare Kanarb (Fimasartan) and Cozaar® (Losartan) in Adult Patients With Grade I-II Arterial Hypertension

Arterial Hypertension

Russian Federation
Imperial College London
Medical Research Council; Covance

Completed

Study of the Gut Hormone Analogue Y14 in Adult Subjects

Obesity | Diabetes Mellitus

United Kingdom
Inimmune Corporation
Avance Clinical Pty Ltd.

Not yet recruiting

Trial of INI-4001 in Patients With Advanced Solid Tumours

Advanced Solid Tumor

Australia
Inimmune Corporation
Avance Clinical Pty Ltd.

Recruiting

Trial of INI-2004 in Healthy Volunteers and Participants With Allergic Rhinitis.

Allergic Rhinitis | Allergic Rhinitis Due to Weed Pollen

Australia
R.J. Reynolds Tobacco Company
University of Louisville; Covance; Analytisch-biologisches Forschungslabor GmbH; Arista Laboratories and other collaborators

Completed

Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus (QoL)

Cigarette Smoking

United States
The Mediterranean Institute for the Advance of...
Carlos III Health Institute; Preventive Services and Health Promotion Research...

Completed

Effectiveness of the "7H" Intervention to Reduce Frequent Attendance in Primary Care ("7H")

Frequent Attenders

Spain
University of Toronto
Advance Foods and Materials Network

Completed

Attidutes and Understanding of Oat Fibre Claims on Food Labels

General Population | Consumer Research

Canada
Memorial Sloan Kettering Cancer Center
Iovance Biotherapeutics, Inc.

Active, not recruiting

A Study of LN-144 in People With Metastatic Melanoma to the Brain

Metastatic Melanoma

United States
Gilead Sciences
Covance; ClinPhone, Inc.; Chiltern International Inc.

Completed

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

Cystic Fibrosis

Belgium, France, Germany, Italy, Netherlands, Spain, United States, Ireland, United Kingdom, Portugal, Austria, Denmark, Switzerland
Teva Branded Pharmaceutical Products R&D, Inc.
Covance

Terminated

A Study to Investigate the Absorption, Metabolism and Excretion of Talampanel

Healthy

United States
Vance Thompson Vision
Alcon Research

Completed

Analysis of Defocus Curve of Pre-Presbyopic and Emerging Presbyopic Patients

Presbyopia

United States
Yolanda de Diego Otero

Completed

Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome (SXF-TRA152)

Fragile X Syndrome

Spain
The Mediterranean Institute for the Advance of...
Carlos III Health Institute; Andaluz Health Service; Preventive Services and...

Completed

Primary Prevention of Major Depression Based on the Level and Profile of Risk of Primary Care Attenders: Cluster, Controlled, Randomised Trial (predictD-CCRT)

Depression

Spain
Midwest Evaluation & Research
Avance Clinical Pty Ltd.

Recruiting

AVANCE-Houston FRAMEWorks Program Evaluation

Adults

United States
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy Volunteers

Bacterial Infections | Infectious Diseases

Australia
Yolanda de Diego Otero

Completed

Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly.

Depression

Spain
Memorial Sloan Kettering Cancer Center
Iovance Biotherapeutics, Inc.

Recruiting

Pilot Trial of Autologous Tumor Infiltrating Lymphocytes (LN-144) for Patients With Metastatic Uveal Melanoma

Melanoma | Metastatic Melanoma | Metastatic Uveal Melanoma | Uveal Melanoma

United States
PeriPharm
Imprimis Pharmaceuticals, Inc.; Advance Dosage Forms, Inc.

Terminated

Economic Impact of Dropless Therapy Versus Usual Care for Cataract Surgery: A Real-World Study.

Cataract Surgery

Canada
Zachary Gerut
Advance Biofactures Corporation

Completed

A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma

Lipoma

United States
University of Toronto
Advance Foods and Materials Network

Completed

Genetic Information and Dietary Intake Behaviour

Healthy

Canada
University of Toronto
Advance Foods and Materials Network

Completed

Attitudes and Understanding of Plant Sterol Claims on Food Labels

General Population | Consumer Research

Canada
Midwest Evaluation & Research
Avance Clinical Pty Ltd.

Recruiting

AVANCE-Houston Building Futures Program Evaluation

Youth

United States
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Terminated

The Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of BWC0977 in Healthy Adult Volunteers

Bacterial Infections | Infectious Diseases

Australia
Brandon Baartman

Recruiting

Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Photorefractive Keratectomy (PRK)

Dry Eye

United States
Vance Thompson Vision
Ocular Therapeutix, Inc.

Completed

The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study

Refractive Surgery

United States
Odyssey Group International, Inc.
Avance Clinical Pty Ltd.

Recruiting

A First in Human Study of the Safety, Tolerability and Pharmacokinetics of PRV-002 in Healthy Volunteers

Traumatic Brain Injury (TBI)

Australia
OncoC4, Inc.
Avance Clinical; OncoC4 AU Pty Ltd

Recruiting

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors (PRESERVE-009)

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Fallopian Tube Cancer | Non Small Cell Lung Cancer | Bile Duct Cancer | Bladder Cancer | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Primary Peritoneal... and other conditions

Australia
Reata, a wholly owned subsidiary of Biogen
Covance

Completed

A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

Healthy Adult Subjects

United States
SK Life Science, Inc.
Covance; Spaulding Clinical Research LLC

Completed

Single-Dose Escalation Study Followed by a Multiple-Dose Escalation Study of SKL24741 in Healthy Subjects

Healthy

United States
Shanghai JMT-Bio Inc.
Quintiles, Inc.; Covance; KingMed Diagnostics

Unknown

Safety, Tolerability and PK/PD of JMT103 in Patients With Bone Metastases From Tumors (JMT103)

Bone Metastases

China

Clinical Trials Sponsored by Nuvance Health

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Saudi Arabia

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