Clinical Trials Sponsored by Orphan Australia

Total 1645 results

FDA Office of Orphan Products Development
Duke University

Completed

Randomized Study of 3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome

Lambert-Eaton Myasthenic Syndrome
FDA Office of Orphan Products Development
Duke University

Completed

Mycophenolate Mofetil in Myasthenia Gravis

Myasthenia Gravis
Georgetown University

Completed

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

End Stage Renal Disease | Hyperhomocysteinemia

United States
FDA Office of Orphan Products Development
Vanderbilt University

Completed

Randomized Study of Recombinant Human Growth Hormone in Patients on Chronic Hemodialysis or Peritoneal Dialysis

Kidney Failure, Chronic

United States
FDA Office of Orphan Products Development
Curis, Inc.

Unknown

Phase III Study of Chondrocyte Alginate Gel Suspension in Pediatric Patients With Vesicoureteral Reflux

Vesicoureteral Reflux
Mayo Clinic

Terminated

Randomized Study of Intravenous Immunoglobulin (IVIg) in Patients With Subacute Proximal Diabetic Neuropathy

Diabetic Neuropathies
The University of Queensland
Princess Alexandra Hospital, Brisbane, Australia; Macquarie University, Australia

Recruiting

A Practice Change for Patients With Severe Chronic, Clinically Unexplained Gastrointestinal Symptoms

Gastrointestinal Diseases | Irritable Bowel Syndrome

Australia
Neuroscience Trials Australia
National Health and Medical Research Council, Australia; Monash University

Active, not recruiting

Trial of EXenatide in Acute Ischaemic Stroke (TEXAIS)

Acute Ischemic Stroke

Australia, Finland, New Zealand
Peter MacCallum Cancer Centre, Australia

Recruiting

Siderophore-labelled Positron Emission Tomography for Correlating Invasive Fungal InfeCtions (SPECIFIC)

Invasive Fungal Infections

Australia
Otsuka Australia Pharmaceutical Pty Ltd

Recruiting

A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia (PREFER-HMA)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Leukemia, Myelomonocytic, Chronic | Patient Preference

New Zealand, Australia
Peter MacCallum Cancer Centre, Australia

Recruiting

Genetically Risk-Stratified Venetoclax, Ibrutinib, Rituximab (± Navitoclax) in Relapsed/Refractory Mantle Cell Lymphoma

Mantle Cell Lymphoma Refractory

Australia
The Bionics Institute of Australia

Recruiting

Improving Early Intervention in Hearing Impaired Children Using Functional Near-Infrared Spectroscopy (fNIRS)

Hearing Impairment

Australia
Peter MacCallum Cancer Centre, Australia

Recruiting

Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men With Metastatic Castration-Resistant Prostate Cancer (AlphaBet)

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer | mCRPC

Australia
ES Therapeutics Australia Pty Ltd

Recruiting

Efficacy, Safety, and Pharmacokinetics of ES-481 in Adult Patients With Essential Tremors

Tremor, Essential

Canada
Peter MacCallum Cancer Centre, Australia

Recruiting

PARP Inhibitor With 177Lu-DOTA-Octreotate PRRT in Patients With Neuroendocrine Tumours (PARLuNET)

Neuroendocrine Tumors

Australia
Akesobio Australia Pty Ltd

Recruiting

Phase 2 Study of Efficacy and Safety of AK120, in Subjects With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

United States, Australia, New Zealand
Peter MacCallum Cancer Centre, Australia

Recruiting

NeoAdjuvant Pembrolizumab and STEreotactic Radiotherapy Prior to Nephrectomy for Renal Cell Carcinoma (NAPSTER)

Renal Cell Carcinoma, Clear Cell, Somatic

Australia
Peter MacCallum Cancer Centre, Australia

Recruiting

ProsTIC Registry of Men Treated With PSMA Theranostics

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

Australia
Peter MacCallum Cancer Centre, Australia

Recruiting

Encorafenib, Binimetinib and Palbociclib in BRAF-mutant Metastatic Melanoma CELEBRATE (CELEBRATE)

Melanoma | Metastasis

Australia
Akesobio Australia Pty Ltd

Recruiting

A Study of AK112, a PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors

Neoplasms Malignant

Australia
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

EValuation of radIOLigand Treatment in mEn With Metastatic Castration-resistant Prostate Cancer With [161Tb]Tb-PSMA-I&T (VIOLET)

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

Australia
Peter MacCallum Cancer Centre, Australia

Terminated

Phase 0 of 18F FPM Using PET/CT in Patients With a Variety of Malignancies

Squamous Cell Carcinoma

Australia
Procyrion
Procyrion Australia Pty Ltd

Active, not recruiting

Aortix Therapy for Perioperative Reduction of Kidney Injury (A Priori)

Acute Kidney Injury

Australia
Otsuka Australia Pharmaceutical Pty Ltd

Completed

Refine and Assess the Readability of Patient, Carer, and Clinician Treatment Preference in Myelodysplasia Questionnaire (TPMQ)

Myelodysplastic Syndrome (MDS)

Australia
Peter MacCallum Cancer Centre, Australia

Completed

Avelumab With Chemoradiation in Locally Advanced Rectal Cancer

Rectal Cancer

Australia
Bod Australia
Drug Science, UK

Completed

Feasibility of Cannabidiol for the Treatment of Long COVID

Long COVID

United Kingdom
Akesobio Australia Pty Ltd

Active, not recruiting

Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK105 in Subjects With Advanced Solid Tumors

Advanced Cancer

Australia
Peter MacCallum Cancer Centre, Australia

Completed

Sequencing of Stereotactic Ablative Body Radiotherapy in Combination With PD-1 Blockade Using Pembrolizumab in Metastatic Non-Small Cell Lung Carcinoma (SABRseq)

Non-small Cell Lung Cancer

Australia, Canada
Peter MacCallum Cancer Centre, Australia

Completed

High Intensity Functional Image Guided Vmat Lung Evasion (HI-FIVE)

Non Small Cell Lung Cancer Stage III

Australia
Peter MacCallum Cancer Centre, Australia

Completed

Panobinostat Biological Correlates Study (VEG VCA1)

Multiple Myeloma | Nodal Lymphoma | Lymphoma With Cutaneous Involvement | Lymphoma in Leukemic Phase | Marrow Involvement With Lymphoma

Australia
Peter MacCallum Cancer Centre, Australia

Terminated

A Study of APR-246 in Oesophageal Cancer (APROC)

Oesophageal Carcinoma

Australia
Center for Eye Research Australia

Completed

Laser Intervention in Early Age-Related Macular Degeneration Study (LEAD)

Age-related Macular Degeneration

Australia
Akesobio Australia Pty Ltd

Unknown

Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK104 in Subjects With Advanced Solid Tumors

Advanced Cancer

Australia
Calvary Mater Newcastle, Australia
Abbott

Completed

PROstate Cancer Imaging, Treatment and Toxicity (PROCITT) (PROCITT)

Prostate Cancer

Australia
Center for Eye Research Australia

Completed

Pilot Study of a Suprachoroidal Retinal Prosthesis

Retinitis Pigmentosa | Choroideremia

Australia
University of Notre Dame Australia

Unknown

Effect on Migraine Frequency of Combined Anti-oxidant Therapy: The MIGRANT Study. (MIGRANT)

Migraine, Headaches
Mercy Hospital for Women, Australia

Completed

The Effect of Sildenafil in Preterm Infants With Evolving Chronic Lung Disease

Lung Diseases

Australia
Peter MacCallum Cancer Centre, Australia

Completed

A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer

Rectal Cancer

Australia
International Diabetes Institute, Australia
GlaxoSmithKline

Completed

GIANT: General Practitioner Implementation in Asia of Normoglycaemic Targets (GIANT)

Type 2 Diabetes Mellitus

China, Indonesia, Korea, Republic of, Malaysia, Philippines, Singapore, Taiwan, Thailand, Vietnam
National Ageing Research Institute, Australia

Unknown

Evaluating the Effects of Music Interventions on Hospitalised People With Dementia

Dementia | Lewy Body Disease | Dementia, Vascular | Alzheimer's Disease

Australia
The University of Western Australia

Completed

Effect of Abdominal Obesity on Lipoprotein Metabolism

Obesity | Insulin Resistance | Dyslipidemia

Australia
National Ageing Research Institute, Australia

Unknown

RCT to Reduce Further Falls and Injuries for Older Fallers Presenting to an Emergency Department

Accidental Falls

Australia
Amelia Gulliver
Australian Institute of Sport

Completed

The Elite Athlete Mental Health Strategy Trial (TEAMS)

Mental Health Help-Seeking

Australia
Orphalan
Ergomed

Recruiting

International Wilson's Disease Patient Registry (iWilson Registry)

Wilson's Disease

Spain, United Kingdom, Belgium, Germany, Poland, France, Saudi Arabia
TVAX Biomedical
FDA Office of Orphan Products Development

Recruiting

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme of Brain

United States
Bioverativ, a Sanofi company
Swedish Orphan Biovitrum

Completed

Study to Determine the Safety and Efficacy of rFIXFc in Previously Untreated Males With Severe Hemophilia B (PUPs B-LONG)

Hemophilia B

United States, Italy, Ireland, New Zealand, United Kingdom, Australia, Netherlands, Denmark, Poland, Sweden, France
Assistance Publique - Hôpitaux de Paris
Swedish Orphan Biovitrum

Completed

Anakinra and Kawasaki Disease (KAWAKINRA)

Children | Kawasaki Disease

France
Jazz Pharmaceuticals
FDA Office of Orphan Products Development

Completed

Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease in Hematopoetic Stem Cell Transplant Patients

Severe Hepatic Veno-Occlusive Disease

United States, Canada
Emory University

Terminated

Randomized Study of Plasmapheresis or Human Immunoglobulin Infusion in Childhood Guillain-Barre Syndrome

Guillain-Barre Syndrome
Columbia University

Completed

Randomized Study of Human Parathyroid Hormone in Middle-Aged Men With Idiopathic Osteoporosis

Osteoporosis

United States

Clinical Trials Sponsored by Orphan Australia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Djibouti

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations