Clinical Trials Sponsored by Progenics Pharmaceuticals, Inc.

Total 4969 results

Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene

Pharmacokinetics

United States
Napo Pharmaceuticals, Inc.

Completed

Effects of Crofelemer on the Gut Microbiome in Healthy Volunteers and in HIV+ Patients With Non-Infectious Diarrhea

Acquired Immunodeficiency Syndrome | HIV/AIDS | Healthy Volunteers | Human Immunodeficiency Virus | HIV Diarrhea

United States
Spectrum Pharmaceuticals, Inc

Completed

The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the Prostate

Benign Prostatic Hypertrophy

United States
Pacira Pharmaceuticals, Inc

Terminated

Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery

Postoperative Pain Management

United States
Spectrum Pharmaceuticals, Inc

Terminated

Phase II Study of SPI-1620 in Combination With Docetaxel as a Second-Line to Treat Biliary Cancer

Biliary Cancer

United States
Spectrum Pharmaceuticals, Inc

Terminated

Rituximab or Zevalin - Efficacy Trial of Therapeutic Alternatives (RoZetta)

Follicular Lymphoma

United States
Spectrum Pharmaceuticals, Inc

Terminated

A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL

Acute Lymphoblastic Leukemia (ALL)

United States
Spectrum Pharmaceuticals, Inc

Completed

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Metastatic Cancer

France, United States, Canada, Belgium, Italy, Australia, United Kingdom, Germany, Hungary
Ironwood Pharmaceuticals, Inc.

Completed

Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

United States, Canada
Diffusion Pharmaceuticals Inc

Terminated

Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects (INTACT)

Glioblastoma

United States
Supernus Pharmaceuticals, Inc.

Completed

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) Low Dose in Children With ADHD

ADHD

United States
Supernus Pharmaceuticals, Inc.

Completed

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) High Dose in Adolescents With ADHD

ADHD

United States
Pacira Pharmaceuticals, Inc

Completed

TAP-patients With Robotic Assisted Lap Prostatectomy (TAP)

Analgesia | Prostatectomy | Postsurgical Pain

United States
Catalyst Pharmaceuticals, Inc.

Completed

Controlled Trial to Evaluate Amifampridine Phosphate in Spinal Muscular Atrophy Type 3 Patients

Muscular Atrophy, Spinal

Italy
Aurinia Pharmaceuticals Inc.

Completed

AURA-LV: Aurinia Urinary Protein Reduction Active - Lupus With Voclosporin (AURA-LV) (AURA-LV)

Lupus Nephritis

United States, Bangladesh, Belarus, Bulgaria, China, Ecuador, Georgia, Guatemala, Korea, Republic of, Mexico, Philippines, Poland, Russian Federation, Serbia, Singapore, Spain, Sri Lanka, Taiwan, Thailand, Ukraine
Corbus Pharmaceuticals Inc.

Terminated

Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic Sclerosis

Diffuse Cutaneous Systemic Sclerosis

United States
Catalyst Pharmaceuticals, Inc.

Completed

A Safety, Tolerability and Pharmacokinetic Study of CPP-115

Cocaine Dependency

United States
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With DED (STRIDE 3)

Kerato Conjunctivitis Sicca

United States
Amphastar Pharmaceuticals, Inc.

Completed

Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals

Asthma | Pharmacokinetics | Anaphylaxis | Epinephrine | Albuterol

United States
Spectrum Pharmaceuticals, Inc

Completed

Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)

Bladder Cancer

United States
Eagle Pharmaceuticals, Inc.

Terminated

Efficacy and Safety Study of Ryanodex as Adjuvant Treatment in Subjects With Psychostimulant Drug-Induced Toxicity (PDIT)

Drug Toxicity Psychotropic Agents Psychostimulants

United States
Corbus Pharmaceuticals Inc.

Terminated

Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis (RESOLVE-1)

Diffuse Cutaneous Systemic Sclerosis

United States, Switzerland, Korea, Republic of, Australia, Netherlands, Israel, United Kingdom, Germany, Japan, Spain, Poland, Canada
Aurinia Pharmaceuticals Inc.

Completed

Aurinia Early Urinary Protein Reduction Predicts Response (AURION)

Lupus Nephritis

Malaysia
Pacira Pharmaceuticals, Inc

Completed

Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty

Pain

United States
Pacira Pharmaceuticals, Inc

Completed

Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy

Pain

United States
Scilex Pharmaceuticals, Inc.

Completed

Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% With Water Exposure

Healthy

United States
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
Afferent Pharmaceuticals, Inc.

Completed

Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)

Refractory Chronic Cough

United Kingdom
Tonix Pharmaceuticals, Inc.

Terminated

A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Participants With PTSD (RECOVERY)

PTSD

United States
Ionis Pharmaceuticals, Inc.

Completed

A Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of IONIS-ENaCRx in Healthy Volunteers and Patients With Cystic Fibrosis

Cystic Fibrosis | Healthy Subjects

United Kingdom, Germany
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease (STRIDE 1)

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation (Hawaii-1)

Ocular Infections, Irritations and Inflammations

United States
Serenity Pharmaceuticals, Inc.

Completed

Long Term Safety Assessment of SER120 in Patients With Nocturia

Nocturia

United States
Pacira Pharmaceuticals, Inc

Completed

Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing Bunionectomy

Bunion

United States
Apellis Pharmaceuticals, Inc.

Completed

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease (STRIDE 2)

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
Madrigal Pharmaceuticals, Inc.

Completed

Drug Interaction Study of MGL-3196 With Pioglitazone

Healthy

United States
Pacira Pharmaceuticals, Inc

Completed

Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arthroplasty

Pain

United States
PhaseBio Pharmaceuticals Inc.

Terminated

Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). (VANGARD)

Pneumonia | Respiratory Failure | Respiratory Insufficiency | COVID 19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Coronavirus | Cytokine Storm | Pulmonary Edema | Cardiac Event | Respiratory Complication | Cardiac Dysfunction | Hypoxemic Respiratory Failure | Hypoxic Respiratory Failure | Cardiac Failure | Cardiac... and other conditions

United States
Pacira Pharmaceuticals, Inc

Terminated

Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in Subjects Undergoing TKA

Total Knee Arthroplasty

United States
Pacira Pharmaceuticals, Inc

Completed

Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty

Postoperative Pain

United States
Milestone Pharmaceuticals Inc.

Terminated

The PSVT Place Registry.Paroxysmal Supraventricular Tachycardia (PSVT) Registry.

Paroxysmal Supraventricular Tachycardia (PSVT)

United States
Pacira Pharmaceuticals, Inc

Completed

Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in Total Knee Arthroplasty

Pain

United States, Belgium, Denmark
Afferent Pharmaceuticals, Inc.

Completed

A Study to Assess the Efficacy of Gefapixant (MK-7264/AF-219), in Participants With Chronic Cough (MK-7264-006) (EPICC)

Chronic Cough
Edison Pharmaceuticals Inc

Completed

Protective Effects of EPI-743 on Noise-Induced Hearing Loss

Noise-induced Hearing Loss

United States
Serenity Pharmaceuticals, Inc.

Completed

Study to Investigate the Safety and Pharmacokinetics of SER120 Nasal Spray in Elderly Patients With Nocturia

Nocturia

United States
Spectrum Pharmaceuticals, Inc

Completed

Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC) Chemotherapy

Breast Cancer | Pharmacokinetics

United States
Serenity Pharmaceuticals, Inc.

Completed

Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia - DB4 (DB4)

Nocturia

United States
Crinetics Pharmaceuticals Inc.

Completed

A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers

Healthy Volunteers

Australia
Hinova Pharmaceuticals Inc.

Completed

A Study Evaluating HC-1119 Single-Dose Pharmacokinetics and Effect of Food on Its Pharmacokinetics

Metastatic Castration Resistant Prostate Cancer

China

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