Clinical Trials Sponsored by Royal Children's Hospital

Total 8057 results

Murdoch Childrens Research Institute
Royal Children's Hospital

Recruiting

Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children (CHOICE UTI)

Infection | Pediatric Infectious Disease | Complicated Urinary Tract Infection

Australia, New Zealand
Royal Children's Hospital

Completed

SWC on aEEG in Post-surgical Neonates on Morphine and Midazolam

Analgesia | Surgery | Sedation | Newborn | Neurology
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Murdoch Childrens Research Institute
Royal Children's Hospital; Royal Hospital For Women

Completed

RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates

Sepsis | Bacteremia | Infection

Australia
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Royal Children's Hospital; Monash Health; Royal...

Not yet recruiting

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) (VANCAPP)

Infections | Sepsis | Bacteremia

Australia
Boston Children's Hospital
Food and Drug Administration (FDA); Royal Children's Hospital; Murdoch Childrens... and other collaborators

Completed

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants (GAS)

Inguinal Hernia

United States, Canada, Australia, Italy, United Kingdom, Netherlands, New Zealand
Murdoch Childrens Research Institute
Royal Children's Hospital; Monash Health

Recruiting

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (MIST+)

Snoring | Tonsillar Hypertrophy | Sleep Disorder; Breathing-Related | Obstructive Sleep Apnea of Child | Sleep Disorders in Children | Adenoidal Disorder

Australia
Murdoch Childrens Research Institute
University of Otago; Sydney Children's Hospitals Network; Royal Children's Hospital and other collaborators

Completed

Improving Dosing of Vancomycin in Young Infants With Infections (VANCAPP)

Sepsis | Bacteremia | Infection

Australia
John Hunter Children's Hospital
Sydney Children's Hospitals Network; Royal Children's Hospital; Royal North Shore... and other collaborators

Unknown

Bolus Insulin Card Calculator Randomised Controlled Study

Type 1 Diabetes

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; Mercy Hospital for Women, Australia

Completed

A Trial Investigating the Influence of BCG and Hepatitis B Immunisation at Birth on Neonatal Immune Responses: The Early Life Vaccines and Immunity Study (ELVIS)

Innate Immune Response

Australia
University of Manchester
Royal Children's Hospital

Completed

Triple P for Parents of Children With a Diagnosis of Cancer

Cancer

United Kingdom
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Murdoch Childrens Research Institute
Bill and Melinda Gates Foundation; Royal Children's Hospital

Completed

BCG Vaccination to Protect Healthcare Workers Against COVID-19 (BRACE)

COVID-19 | Corona Virus Infection | Coronavirus Disease 2019 (COVID-19) | Respiratory Illness

Australia, Brazil, Netherlands, Spain, United Kingdom
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Monash Health; Cerebral Palsy Alliance; The... and other collaborators

Completed

Stem Cells in Umbilical Blood Infusion for CP (SCUBI-CP)

Cerebral Palsy

Australia
Belfast Health and Social Care Trust
Barts & The London NHS Trust; University Hospitals, Leicester; Bristol Royal... and other collaborators

Completed

Febrile Infants - Diagnostic Assessment and Outcome (FIDO)

Bacterial Infections | Urinary Tract Infections | Meningitis, Bacterial

United Kingdom, Ireland
The Hospital for Sick Children
Children's Hospital of Eastern Ontario; Royal University Hospital Foundation; Connecticut Children's Medical Center

Active, not recruiting

iPeer2Peer Program for Youth With Sickle Cell Disease

Sickle Cell Disease

United States, Canada
Neuroscience Research Australia
Sydney Children's Hospitals Network; Royal Children's Hospital; The George Institute

Completed

Risk Models to Optimise Prophylaxis Schedules in Children With Haemophilia (MOrPH)

Hemophilia
Kristina Hardy
Children's Hospital Los Angeles; Sydney Children's Hospitals Network; Royal Children... and other collaborators

Completed

Efficacy of Computerized Cognitive Training and Stimulant Medication in Neurofibromatosis Type 1 (COGTRAIN)

Neurofibromatosis Type 1

United States
Murdoch Childrens Research Institute
Royal Children's Hospital; University of Melbourne; Mercy Hospital for Women,...

Active, not recruiting

Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction (MIS BAIR)

Respiratory Tract Infections | Allergy | Eczema

Australia
Victor Blanchette
Queen's University; Sydney Children's Hospitals Network; Royal Children's Hospital and other collaborators

Unknown

Evaluation of a Simple Pharmacokinetic Tool (myPKFiT™) to Guide Personalized Factor VIII Dosing in Patients With Hemophilia

Hemophilia A
Telethon Kids Institute
National Health and Medical Research Council, Australia; Sydney Children's... and other collaborators

Completed

Pertussis Immunisation and Food Allergy (PIFA)

Food Allergy

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; RCH League of Former Trainees and Associates Inc

Completed

Vaccination Coverage and Uptake in Young People Experiencing or at Risk of Homelessness

Homeless Youth

Australia
Seoul National University Hospital
Seoul National University Bundang Hospital; Children's Hospital Los Angeles; Royal...

Recruiting

Effectiveness of Extended Reality CPR Training Methods

Virtual Reality | Basic Cardiac Life Support

Korea, Republic of
Royal Perth Hospital

Recruiting

Neuroinflammation in Hypertension Study (MINIHT)

Resistant Hypertension

Australia
Royal Perth Hospital

Completed

Role of Sympathetic Activation in Ischemia Reperfusion Injury

Central Sympathetic Nervous System Diseases

Australia
Royal Hobart Hospital

Terminated

A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery

Recurrence | Varicose Veins | Wound Infection

Australia
Royal Hobart Hospital

Terminated

Local Anaesthetic Following Hernia Repair

Inguinal Hernias

Australia
Royal Adelaide Hospital

Completed

A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases

Neoplasm Metastasis | Brain Neoplasm

Australia
Royal Hobart Hospital

Unknown

U Clip Study - Study to Compare U Clip Anastomosis With Conventional Continuous Prolene Anastomosis

Haemodialysis

Australia
Royal Hospital, Oman

Not yet recruiting

Sevoflurane Wash in Method Using Conventional Flows Versus Low Flows of 0.5L

Inhalation; Gas
Royal Perth Hospital

Recruiting

Effects of Sodium-glucose Co-transporter-2( SGLT-2 ) Inhibition on Sympathetic Nervous System Activity in Humans (EMPA-SNS)

Obesity | Type 2 Diabetes Mellitus | Metabolic Syndrome

Australia
Royal Alexandra Hospital

Completed

The Predictive Value of Clinical and Immunological Factors in the Development of Pneumonia After Traumatic Brain Injury

Traumatic Brain Injury

Canada
Royal Perth Hospital

Recruiting

Image Enhanced Endoscopy IBD

Inflammatory Bowel Diseases | Dysplasia

Australia
Royal Adelaide Hospital

Completed

Effects of Sitagliptin on Gastric Emptying, Glycaemia and Blood Pressure in Type 2 Diabetes

Diabetes Mellitus | Gastroparesis

Australia
Royal Adelaide Hospital

Completed

Effects of Water and Glucose Drinks on Cardiovascular Function in Subjects With and Without Postprandial Hypotension

Autonomic Nervous System Diseases | Blood Pressure | Hypotension | Baroreflex Failure
Royal Hobart Hospital

Unknown

A Randomised, Blinded Study on Laparoscopic Mesh Reinforcement for Chronic Groin Pain

Chronic Groin Pain

Australia
Murdoch Childrens Research Institute
Baylor College of Medicine; Children's Hospital of Philadelphia; Boston Children... and other collaborators

Active, not recruiting

A Study to Compare the Long-term Outcomes After Two Different Anaesthetics (TREX)

Child Development | Anesthesia | Neurotoxicity

United States, Australia, Italy, Spain
Alberta Children's Hospital
The Hospital for Sick Children; British Columbia Children's Hospital; Stollery...

Terminated

Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure (GLP-2-01)

Short Bowel Syndrome | Intestinal Failure

Canada
Birmingham Women's and Children's NHS Foundation...
University of Sheffield; Royal Manchester Children' s Hospital, Manchester

Completed

Whole Body Vibration Training in Children With Osteogenesis Imperfecta and Limited Mobility

Osteogenesis Imperfecta

United Kingdom
Royal Perth Hospital
Royal Perth Hospital Medical Research Foundation

Completed

Behavioural Intervention for Dysphagia in Acute Stroke

Dysphagia

Australia
The Hospital for Sick Children
Alberta Children's Hospital; British Columbia Children's Hospital

Completed

iCanCope With Pain: Usability and Feasibility Testing of a Smartphone Application to Manage Pain in Youth With Arthritis

Juvenile Idiopathic Arthritis

Canada
Nationwide Children's Hospital
Ann & Robert H Lurie Children's Hospital of Chicago; Children's Hospital Medical... and other collaborators

Active, not recruiting

Multi-institutional Trial of Non-operative Management of Appendicitis

Appendicitis

United States
Shriners Hospitals for Children
Children's Hospital Medical Center, Cincinnati

Completed

Differential Effects of Zolpidem Versus Ramelteon in Burned Children (Sleep3)

Burns | Sleep

United States
Murdoch Childrens Research Institute
Baylor College of Medicine; Children's Hospital of Philadelphia; University Hospital... and other collaborators

Completed

The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.

Surgical Procedures, Operative

United States, Singapore, Australia
Royal Victoria Hospital, Canada
Royal Victoria Foundation; Alectra

Not yet recruiting

Eliciting Informed Goals of Care in Elderly Patients (ASKMEGOC)

End of Life | Patient Preference | Goals of Care
Shaare Zedek Medical Center
The Hospital for Sick Children; Rambam Health Care Campus; Children's Hospital... and other collaborators

Completed

The ImageKids Study: Developing the pMEDIC and the PICMI

Crohn's Disease

Israel
Shriners Hospitals for Children
Children's Hospital Medical Center, Cincinnati

Completed

The Effect of Healing Touch on Sleep (Sleep7)

Elective Reconstructive Surgery Population

United States
Shriners Hospitals for Children
Children's Hospital Medical Center, Cincinnati

Completed

Circadian Rhythm of Melatonin in Burns (Sleep4)

Burns | Sleep

United States
The Hospital for Sick Children
Xiamen Children's Hospital

Not yet recruiting

Intestinal Perfusion After Feeding in Preterm and Term Infants

Necrotizing Enterocolitis | Premature

China
McMaster Children's Hospital
The Hospital for Sick Children

Recruiting

Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth

Small Intestinal Bacterial Overgrowth

Canada

Clinical Trials Sponsored by Royal Children's Hospital

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