Clinical Trials Sponsored by Singapore Eye Research Institute

Total 246 results

Smith-Kettlewell Eye Research Institute

Recruiting

Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment

Blindness | Low Vision | Blindness, Acquired | Blindness, Complete

United States
Periman Eye Institute
Alcon Research

Recruiting

Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users

Dry Eye | Meibomian Gland Dysfunction

United States
National University Hospital, Singapore
AstraZeneca; Singapore Clinical Research Institute

Unknown

Phase II Study of AZD9291 in Advanced Stage NSCLC With EGFR and T790M Mutations Detected in Plasma Ct-DNA (PLASMA)

Carcinoma, Non-Small-Cell Lung

Taiwan, Hong Kong, Thailand, Singapore, Korea, Republic of
Schepens Eye Research Institute

Completed

Retinal Blood Flow and Microthrombi in Type 1 Diabetes

Diabetes | Diabetic Retinopathy

United States
Singapore General Hospital
National Cancer Centre, Singapore; National Medical Research Council (NMRC)... and other collaborators

Unknown

Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC) (SIRveNIB)

Hepatocellular Carcinoma

Taiwan, Korea, Republic of, Malaysia, New Zealand, Philippines, Singapore, China, Thailand, Brunei Darussalam, Indonesia, Mongolia, Myanmar
Clinical Nutrition Research Centre, Singapore
Singapore Institute for Clinical Sciences

Completed

Insulin Modelling Based on Plasma Glucose Measures Via a Minimally-Invasive Glucose Sensor

PreDiabetes

Singapore
Seng Gee Lim
National Medical Research Council (NMRC), Singapore; Singapore Clinical Research...

Unknown

Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B (DUAL)

Chronic Hepatitis B

Singapore
National University Hospital, Singapore
Changi General Hospital; National Heart Centre Singapore; Singapore Clinical...

Unknown

Nitrates In Combination With Hydralazine in cardiorEnal Syndrome (NICHE) Study (NICHE)

Cardio-Renal Syndrome

Singapore
Asia Cornea Society
Singapore Clinical Research Institute

Unknown

The Asia Cornea Society Infectious Keratitis Study (ACSIKS)

Corneal Ulcer

Singapore, China, India, Japan, Korea, Republic of, Philippines, Taiwan, Thailand
Clinical Nutrition Research Centre, Singapore
Institute for Infocomm Research

Completed

BRown Fat Activity Measurement With Infrared imaginG tHermography andThermogenesis - the BRIGHT Study (BRIGHT)

Obesity | Energy Expenditure | Adipose Tissue, Brown
University College, London
National University Hospital, Singapore; Singapore Clinical Research Institute...

Completed

Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis (TRUNCATE-TB)

Tuberculosis, Pulmonary

Singapore, Uganda, Thailand, Indonesia, Philippines, India
Singapore Clinical Research Institute
Singapore General Hospital; Duke-NUS Graduate Medical School

Terminated

The Effect of 90-day Oral Testosterone Therapy in Chinese Males With Type 2 Diabetes (T2DM) (OTEST)

Assess the Effects of a the 90-day Oral TS Study Regimen on PSA, IPSS, Haemoglobin and Haematocrit, and to Assess Adverse and Serious Adverse Events.

Singapore
Peregrine Eye and Laser Institute
Alcon Research

Recruiting

Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter (HYPE)

Vitreous Hemorrhage | Retinal Detachment | Epiretinal Membrane | Vitrectomy | Macular Holes | Dislocated Intraocular Lens Into Vitreous | Retained Lens Fragments

Philippines
Stanford University
Smith-Kettlewell Eye Research Institute

Completed

Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants

Hyperbilirubinemia | Infant, Premature | Infant, Low Birth Weight | Kernicterus | Bilirubin-induced Neurologic Dysfunction

United States
Singapore General Hospital
Duke-NUS Graduate Medical School; Singapore Clinical Research Institute; Health... and other collaborators

Completed

The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program

Pre-diabetes

Singapore
National Neuroscience Institute
Singapore Clinical Research Institute; AegisCN LLC

Completed

Evaluation of CN-105 in Subject With Acute Supratentorial Intracerebral Hemorrhage (S-CATCH)

Intracerebral Hemorrhage

Singapore
Oslo University Hospital
Schepens Eye Research Institute; The Norwegian Dry Eye Clinic

Completed

Optimization of the Treatment of Dry Eye Disease Caused by Meibomian Gland Dysfunction

Dry Eye Syndromes | Meibomian Gland Dysfunction

Norway
Silkiss Eye Surgery
Jazz Pharmaceuticals; Smith-Kettlewell Eye Research Institute; Benign Essential...

Completed

Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm

CBD | Blepharospasm | Blepharospasm, Benign Essential

United States
National Taiwan University Hospital
Singapore Clinical Research Institute

Recruiting

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

Out-Of-Hospital Cardiac Arrest

Taiwan
Columbia University
National Eye Institute (NEI); Riverside Research Institute

Completed

Annular Array Ultrasound in Ophthalmology

Diabetic Retinopathy | Posterior Vitreous Detachment

United States
National Cancer Centre, Singapore
Hoffmann-La Roche; Sirtex Medical; Singapore Clinical Research Institute

Recruiting

Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients (STRATUM)

Locally Advanced Hepatocellular Carcinoma

Korea, Republic of, Singapore
National University Hospital, Singapore
Ng Teng Fong General Hospital; Singapore Clinical Research Institute

Completed

Pre- and Apnoeic Oxygenation for RSI in ED (Pre-AeRATE)

Intubation | Oxygen Inhalation Therapy

Singapore
Singapore Clinical Research Institute
ClinDatrix, Inc.; MicroVAX, LLC

Unknown

Safety Study of Human MUC-1 (Mucin-1) Adenoviral Vector Vaccine for Immunotherapy of Epithelial Cancers (MUC-1)

Epithelial Cancers of the Lung, Breast, Ovary, Prostate and Colon

Singapore
Tan Tock Seng Hospital
Singapore Clinical Research Institute

Not yet recruiting

Oral Capsule Faecal Microbiota Transplantation for CPE Decolonization

Carbapenem-Resistant Enterobacteriaceae Infection
Calm Water Therapeutics LLC
Andover Research Eye Institute

Completed

Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops

Dry Eye Disease

United States
East Coast Institute for Research
Alcon Research; Florida Eye Specialists

Recruiting

Effect of Intraocular Lens (IOL) Centration and Tilt on Visual Performance With Clareon® Vivity® IOL Implantation

Cataract | Lenses, Intraocular

United States
CIBA VISION
Bascom Palmer Eye Institute

Completed

Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression

Ocular Comfort

United States
Duke-NUS Graduate Medical School
Singapore General Hospital; Agency for Science, Technology and Research; Singapore... and other collaborators

Completed

Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly (3ECog)

Dementia | Mild Cognitive Impairment | Alzheimer's Disease | Age-Related Cognitive Decline

Singapore
Tan Tock Seng Hospital
Rehabilitation Research Institute of Singapore (RRIS); Singapore-ETH Centre...

Recruiting

Tracking of Upper Limb Sensory and Motor Recovery in Asian Stroke Survivors

Stroke

Singapore
Tychan Pte Ltd.
National University Hospital, Singapore; National University, Singapore; Duke-NUS... and other collaborators

Completed

Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in Humans

Treatment of Acute Zika Virus Infection

Singapore
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Not yet recruiting

Bifocal Spectacles vs. Single Vision Spectacles for Esotropia Greater at Near (ETS3)

Esotropia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

Bevacizumab Treatment For Type 1 ROP (ROP4)

Retinopathy of Prematurity

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent Exotropia (IXT1)

Exotropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Terminated

A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP (ROP3)

Retinopathy of Prematurity

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Base-in Prism Spectacles for Intermittent Exotropia (IXT6)

Exotropia Intermittent

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Low-Dose Atropine for Treatment of Myopia (MTS1)

Myopia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Phase 1 Trial of Bevacizumab Treatment for Severe Retinopathy of Prematurity (ROP1)

Retinopathy of Prematurity

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Withdrawn

Excimer Laser Surgery for Anisometropic Amblyopia (ATS19)

Refractive Errors | Anisometropic Amblyopia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Convergence Insufficiency Treatment Study (CITS)

Convergence Insufficiency

United States
Sengkang General Hospital
Singapore Clinical Research Institute; SingHealth Polyclinics

Completed

Effectiveness of Education, Medication Adjustment and Telemonitoring in Reducing Diabetes Complications During Ramadan

Diabetes Mellitus | Diabetes Complications | Fasting

Singapore
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

Full-Time Occlusion Therapy for Intermittent Exotropia in Children (IXT7)

Intermittent Exotropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Trial of Overminus Spectacle Therapy for Intermittent Exotropia (IXT5)

Intermittent Exotropia

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation (HTS1)

Hyperopia

United States
Singapore Institute for Clinical Sciences
Almond Board of California; National Medical Research Foundation (NMRC) Singapore

Completed

Asian Indian Prediabetes Study (AIPS)

Pre Diabetes

Singapore
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Not yet recruiting

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age (ATS23)

Amblyopia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching (ATS22)

Amblyopia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

A Prospective Observational Study of Adult Strabismus (SAS1)

Convergence Insufficiency | Divergence Insufficiency | Hypertropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Binocular Dig Rush Game Treatment for Amblyopia (ATS20)

Amblyopia

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Observation Versus Occlusion Therapy for Intermittent Exotropia (IXT2)

Exotropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Study of Binocular Computer Activities for Treatment of Amblyopia (ATS18)

Amblyopia

United States

Clinical Trials Sponsored by Singapore Eye Research Institute

Sponsors and Collaborators

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