Clinical Trials Sponsored by University Hospital Hradec Kralove

Total 111 results

University Hospital Hradec Kralove

Not yet recruiting

Role of Brain Specific Biomarkers in Hydrocephalus

Brain Damage | Hydrocephalus, Normal Pressure | Biochemical Lesions Head Region

Czechia
University Hospital Hradec Kralove

Recruiting

Manual Versus Targer-controll Infusion in Reduction of Awareness and Dreaming

Anesthesia Awareness

Czechia
University Hospital Hradec Kralove

Completed

Hemodynamic Changes Due to Prone Position

Prone Position | Hemodynamics Instability

Czechia
University Hospital Hradec Kralove

Completed

Perioperative Fluid Therapy Optimization in Spinal Surgery

Hypovolemia | Hypervolemia

Czechia
University Hospital Hradec Kralove

Unknown

The Influence of Prone Position for Spinal Surgery on Visual Acuity

Vision; Disorder, Loss

Czechia
University Hospital Hradec Kralove

Completed

Glycocalyx Damage in Critically Ill Patients

Critical Illness

Czechia
University Hospital Hradec Kralove

Completed

Evaluation of Lipid Emulsion on GCX in Critically Ill Patients

Endothelial Dysfunction

Czechia
University Hospital Hradec Kralove

Completed

Effect General and Regional Anesthesia on Glycocalyx

Anesthesia | Glycocalyx | Perfused Boundary Region
University Hospital Hradec Kralove

Completed

ANI and SPI Guided Intraoperative Analgesia

Anesthesia

Czechia
University Hospital Hradec Kralove

Terminated

The Effect of Nimodipine on the Postoperative Cognitive Dysfunction

Mild Cognitive Impairment

Czechia
University Hospital Hradec Kralove

Completed

Postoperative Patency of Internal Jugular Vein After Neck Cannula Insertion

Cardiac Surgical Procedure

Czechia
University Hospital Hradec Kralove

Withdrawn

Mild Hypothermia During Intracranial Aneurysm Clipping

Subarachnoid Hemorrhage, Aneurysmal

Czech Republic
University Hospital Hradec Kralove

Completed

Factors Affecting the Effective End-tidal Concentration of Desflurane Anaesthesia

General Anesthetic Drug Adverse Reaction

Czech Republic
University Hospital Hradec Kralove

Recruiting

The Impact of Intra-operative Fluid Infusion Rate on Microcirculation

Fluid Therapy | Microcirculation | Hemodilution

Czechia
University Hospital Hradec Kralove

Recruiting

The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus

Brain Damage | Hydrocephalus | General Anesthetics Toxicity

Czechia
University Hospital Hradec Kralove

Recruiting

Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients

COVID-19 Respiratory Infection

Czechia
University Hospital Hradec Kralove

Recruiting

Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study

Subarachnoid Hemorrhage

Czechia
University Hospital Hradec Kralove

Recruiting

Haemodynamical Optimization During Brain Surgery

Brain Edema

Czechia
University Hospital Hradec Kralove

Completed

COVID-19 Vaccination AZV 2021-2023

COVID-19 | Respiratory Failure | Immunity | Vaccination

Czechia
University Hospital Hradec Kralove

Completed

Can the Prophylactic Administration of Tranexamic Acid Reduce Blood Loss After Robotic-assisted Radical Prostatectomy? (RARPEX)

Robotic-assisted Radical Prostatectomy

Czechia
University Hospital Hradec Kralove

Completed

Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis

Sepsis | Viral Pneumonia

Czechia
University Hospital Hradec Kralove

Completed

Near Infrared Spectroscopy for Detection of Cerebral Desaturation After Positioning for Neurosurgical Procedures

Cognitive Dysfunction | Patient Positioning

Czechia
University Hospital Hradec Kralove

Completed

A Comparison of the Effect of 1.5 Versus 3% NaCl on Brain Relaxation and Microcirculation

Brain Tumors

Czechia
University Hospital Hradec Kralove

Unknown

Treatment of AMD With Rheohemapheresis /RHF/ (TARHF)

Age Related Macular Degeneration

Czech Republic
University Hospital Hradec Kralove

Recruiting

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Organ Transplant Failure or Rejection | Brain Damage Due to Hypoxia | Organ Donors

Czechia
University Hospital Hradec Kralove

Recruiting

Evaluation of the Severity of Right to Left Shunt in PFO Patients After Systemic Embolism

Embolism | Patent Foramen Ovale

Czechia
University Hospital Hradec Kralove

Completed

DNA Damage in Critically Ill COVID-19 Patients

Covid19 | DNA Damage | Organ Failure, Multiple

Czechia
University Hospital Hradec Kralove

Completed

The Depth of Endotracheal Tube Insertion

Intubation Complication

Czechia
University Hospital Hradec Kralove

Unknown

The Aim of This Project is to Verify Whether a Depletion of B Cell Memory Subpopulation ("Marginal-zone-like") CD19 + IgD + CD27 + and CD19 + IgM + CD27 + is a Useful Indicator of Hyposplenism in Patients With Celiac Disease

Celiac Disease

Czechia
University Hospital Hradec Kralove

Completed

Glycocalyx Damage and Beta-lactam Antibiotics in Surgical Critically Ill

Critical Illness

Czechia
University Hospital Hradec Kralove

Completed

The Effect of Blood Pressure on the Postoperative Cognitive Dysfunction

Mild Cognitive Impairment

Czechia
University Hospital Hradec Kralove

Completed

Randomized Controlled Trial Comparing Closed-suction Drain Versus Passive Gravity Drain Following Pancreatic Resection (DRAPA)

Pancreaticoduodenectomy | Distal Pancreatectomy

Czech Republic
University Hospital Hradec Kralove

Unknown

Surgical Treatment of High Perianal Fistulas (LIFTRAF)

Rectal Fistula | Anal Fistula

Czech Republic
University Hospital Hradec Kralove

Unknown

Joint Application of Human Insulin and Rapid Insulin Analogue in Control of Postprandial Glycemia (CPIT)

Diabetes Mellitus, Type 1

Czech Republic
University Hospital Hradec Kralove

Unknown

Congestive Heart Failure: Causes of Sudden Worsening

Congestive Heart Failure

Czech Republic
University Hospital Hradec Kralove
Masaryk University

Recruiting

The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases (INFURO)

Dyspnea

Czechia
University Hospital Hradec Kralove
University Hospital Pilsen

Completed

Effect of Fluid Challenge on Glycocalyx

Sepsis | Septic Shock | Surgery | Endothelial Dysfunction | Anesthesia

Czechia
University Hospital Ostrava
University Hospital Hradec Kralove

Completed

Balloon Eustachian Tuboplasty in Treatment of Chronic Eustachian Tube Dysfunction

Chronic Eustachian Tube Dysfunction | Chronic Recurrent Otitis Media | Effusion After Tympanostomy

Czechia
Charles University, Czech Republic
University Hospital Hradec Kralove

Unknown

Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism (ISIRA)

Primary Aldosteronism

Czech Republic
Palacky University
University Hospital Ostrava; University Hospital Olomouc; Faculty Hospital Kralovske... and other collaborators

Enrolling by invitation

Changes in the Perception of Personal Dignity Over the Course of Dementia (DIDEM)

Dementia | Dignity

Czechia
Brno University Hospital
Faculty Hospital Kralovske Vinohrady; University Hospital Hradec Kralove; General...

Completed

Ofatumumab Added to Dexamethasone in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Czech Republic
Palacky University
University Hospital Ostrava; University Hospital Hradec Kralove

Unknown

Trajectories of Quality of Life by the Elderly in Early Phase of Dementia

Quality of Life | Dementia
University Hospital Hradec Kralove
American Association for Thoracic Surgery

Recruiting

AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis (AOSIS)

Infections | Systemic Inflammatory Response Syndrome | Immunological Abnormality | Aortic Diseases | Thoracic Aortic Aneurysm

Czechia
Zdravotnicka Zachranna Sluzba Kralovehradeckeho...
University Hospital Hradec Kralove

Unknown

Rapid Administration of Blood by HEMS in Trauma (RABBIT)

Wounds and Injuries | Trauma | Acute Coagulopathy

Czechia
University of Defence, Faculty of Military Health...
University Hospital Hradec Kralove

Recruiting

Blood Loss Quantification During Major Abdominal Surgery

Postoperative Complications | Blood Loss, Surgical | Blood Loss, Postoperative

Czechia
University Hospital Hradec Kralove
Bristol-Myers Squibb; GCP-Service International s.r.o.

Completed

Stereotactic Radiotherapy + Anti PD-1 Therapy in Patients With Locally Advanced Unresectable Pancreatic Adenocarcinoma (CA209-9KH)

Locally Advanced Unresectable Pancreatic Adenocarcinoma

Czechia
Jan Gofus, MD, PhD
Charles University, Czech Republic

Recruiting

Physical Performance Testing and Frailty in Prediction of Early Postoperative Course After Cardiac Surgery (Cardiostep)

Frailty | Rehabilitation | Cardiac Surgery | Physical Performance

Czechia
Charles University, Czech Republic
University Hospital Hradec Kralove; Longevitytech.fund a.s.; Clock Foundation; AGECURVE...

Completed

Effects of Plasmapheresis on Aging Biomarkers

Aging | Plasmapheresis

Czechia
Charles University, Czech Republic
University Hospital Pilsen; University Hospital Hradec Kralove; Na Homolce Hospital and other collaborators

Completed

Trial Comparing Radial and Femoral Approach in Primary Percutaneous Coronary Intervention (PCI) (STEMI-RADIAL)

ST Elevation Myocardial Infarction

Czech Republic
Institute for Clinical and Experimental Medicine
Faculty Hospital Kralovske Vinohrady; General University Hospital, Prague; VZW... and other collaborators

Completed

Novel Cardiac Imaging Prognostic Markers of Clinical Outcome in Patients With Chronic Aortic Regurgitation (MOLLI-GLS-Hx)

Aortic Valve Disorder

Czechia, Belgium

Clinical Trials Sponsored by University Hospital Hradec Kralove

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