Clinical Trials Sponsored by VLIR-IUC, Belgium

Total 63 results

University Ghent
Institute of Tropical Medicine, Belgium; Nutrition Third World, Belgium; VLIR-IUC...

Completed

Health Promotion in Adolescents in Ecuador (ACTIVITAL)

Overweight

Ecuador
Institute of Tropical Medicine, Belgium
University Ghent; Nutrition Third World, Belgium; Flemish Interuniversity Council...

Completed

Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso (MISAME2)

Low Birth Weight | Intrauterine Growth Retardation

Burkina Faso
Vir Biotechnology, Inc.

Recruiting

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection (MARCH)

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Malaysia, New Zealand, Taiwan, United Kingdom, Romania, United States, Moldova, Republic of, Canada, Germany, Ukraine
Vir Biotechnology, Inc.

Terminated

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

Influenza A

United States
Vir Biotechnology, Inc.

Completed

Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Germany, Hong Kong, Korea, Republic of, New Zealand, Romania, Singapore, United Kingdom
Vir Biotechnology, Inc.

No longer available

Sotrovimab Expanded Access Treatment Protocol (COVID-19)

Covid19

United States
Vir Biotechnology, Inc.

Recruiting

A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218

Renal Impairment

United States
Vir Biotechnology, Inc.

Recruiting

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Cirrhosis | Hepatic Impairment

United States
Vir Biotechnology, Inc.

Recruiting

SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.

Hepatitis D, Chronic

New Zealand, United Kingdom, Moldova, Republic of, Romania, Bulgaria, Italy, Germany, France, Netherlands
Vir Biotechnology, Inc.

Active, not recruiting

A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, United Kingdom, France, Moldova, Republic of, Romania
Vir Biotechnology, Inc.

Completed

Study of VIR-2482 in Healthy Volunteers

Influenza A

Australia
Vir Biotechnology, Inc.
GlaxoSmithKline

Recruiting

Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC) (COSMIC)

Covid19

United States
Vir Biotechnology, Inc.
GlaxoSmithKline

Terminated

Intramuscular and Intravenous VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19.

Covid19

United States, France, Ukraine
Vir Biotechnology, Inc.
GlaxoSmithKline

Completed

VIR-7831 for the Early Treatment of COVID-19 in Outpatients (COMET-ICE)

Covid19

United States, Canada, Spain, Austria, Brazil, Peru, United Kingdom
GlaxoSmithKline
Vir Biotechnology, Inc.

Terminated

Pharmacokinetics, Pharmacodynamics, and Safety of Single-dose Sotrovimab in High-risk Pediatric Participants With Mild to Moderate COVID-19 (COMET-PACE)

COVID-19

United States
Vir Biotechnology, Inc.
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19 (COMET-PEAK)

Covid19

United States, Canada, Italy, Korea, Republic of, Spain
Vir Biotechnology, Inc.
GlaxoSmithKline

Completed

A Study to Investigate the PK, Safety, and Tolerability of Sotrovimab vs Placebo Administered IV or IM in Japanese and Caucasian Participants

Covid19

United States
Vir Biotechnology, Inc.
Alnylam Pharmaceuticals

Completed

Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis B

Chronic Hepatitis B

Australia, Hong Kong, Korea, Republic of, New Zealand, Thailand
Gilead Sciences
Vir Biotechnology, Inc.

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)

Chronic Hepatitis B

Hong Kong, Korea, Republic of, Denmark, Australia, Thailand, Singapore, United Kingdom, New Zealand
Vir Biotechnology, Inc.
Alnylam Pharmaceuticals

Active, not recruiting

Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Australia, Hong Kong, Korea, Republic of, Malaysia, New Zealand, Thailand
Hipra Scientific, S.L.U
Veristat, Inc.; Asphalion; VHIR

Recruiting

Open-label, Multi-centre, Non-Inferiority Study of Safety and Immunogenicity of BIMERVAX for the Prevention of COVID-19 in Adolescents From 12 Years to Less Than 18 Years of Age.

SARS CoV 2 Infection

Spain
Tracon Pharmaceuticals Inc.
Janssen Pharmaceutica N.V., Belgium

Completed

Phase 1/2A Study of TRC253, an Androgen Receptor Antagonist, in Metastatic Castration-resistant Prostate Cancer Patients

Metastatic Castrate-resistant Prostate Cancer | Adenocarcinoma, Prostate

United States
Brii Biosciences Limited
Vir Biotechnology, Inc.

Active, not recruiting

Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients

Chronic Hepatitis B Virus Infection

Singapore, Thailand, Australia, China, Korea, Republic of
Brii Biosciences Limited
VBI Vaccines Inc.; Vir Biotechnology, Inc.

Completed

Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic HBV Infection

Hepatitis B, Chronic

Australia, China, Korea, Republic of, New Zealand, Singapore, Thailand
Brii Biosciences Limited
Alnylam Pharmaceuticals; Vir Biotechnology, Inc.

Completed

Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China

Hepatitis B, Chronic

China
Vir Biotechnology, Inc.
Bill and Melinda Gates Foundation

Completed

VIR-1111: A Prototype Human CMV-based Vaccine for Human Immunodeficiency Virus (HIV) in Healthy Volunteers

HIV I Infection

United States
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Eloxx Pharmaceuticals, Inc.
SGS Life Sciences, a division of SGS Belgium NV

Completed

Phase 1 Study of ELX-02 in Healthy Adults

Genetic Disease | Nonsense Mutation

Belgium
Eloxx Pharmaceuticals, Inc.
SGS Life Sciences, a division of SGS Belgium NV

Completed

Phase 1 Study of ELX-02 in Healthy Adult Subjects

Genetic Disease | Nonsense Mutation

Belgium
Fred Hutchinson Cancer Center
National Marrow Donor Program; Vir Biotechnology, Inc.

Terminated

Pharmacokinetics of Sotrovimab as Pre-exposure Prophylaxis for COVID-19 in Hematopoietic Stem Cell Transplant Recipients, COVIDMAB Study

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | COVID-19 Infection

United States
Eli Lilly and Company
GlaxoSmithKline; Shanghai Junshi Bioscience Co., Ltd.; Vir Biotechnology, Inc.; AbCellera Biologics Inc...

Completed

A Study of Immune System Proteins in Participants With Mild to Moderate COVID-19 Illness (BLAZE-4)

COVID-19

United States, Puerto Rico, Argentina
Venus MedTech (HangZhou) Inc.
TheraGenesis GmbH of Oppenheim, Germany; IQVIA MedTech BV of Antwerp, Belgium

Not yet recruiting

Observational Study of Venus P-Valve (Registry)

Right Ventricular Outflow Tract Dysfunction
Cliniques universitaires Saint-Luc- Université...
Society for Anesthesia and Resuscitation of Belgium

Completed

Survey: COVID-19 Patients Managed in the Operating Theatre of Belgian Hospitals (COVID)

COVID-19

Belgium
Belgian Group of Digestive Oncology
University Hospital St Luc, Brussels

Recruiting

A Study Evaluating the Efficacy of 5-FU + NALIRI and 5-FU + NALIRINOX for PDAC (NALPAC) (NALPAC)

Metastatic Pancreatic Ductal Adenocarcinoma

Belgium
The Belgian Society of Medical Oncology
Illumina, Inc.; OncoDNA; PierianDx

Recruiting

A Study to Examine the Clinical Value of Comprehensive Genomic Profiling Performed by Belgian NGS Laboratories: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Centre (BALLETT)

Solid Tumor | Metastatic Cancer

Belgium
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo (HIT BSI)

Health Care Utilization | Bloodstream Infection | Febrile Illness | Malaria,Falciparum | Salmonella Infection Non-Typhoid

Congo, The Democratic Republic of the
IUATLD, Inc
Medical Research Council; Institute of Tropical Medicine, Belgium; Liverpool... and other collaborators

Completed

The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB (STREAM)

MDR-TB

Ethiopia, Georgia, India, Moldova, Republic of, Mongolia, South Africa, Uganda
Pharmaxis
ethica Clinical Research Inc.; Europe: KasaConsult bvba, Hoegaarden, Belgium; Argentina: Resolution Latin America; Buenos Aires, Argentina

Completed

Long Term Administration of Inhaled Mannitol in Cystic Fibrosis

Cystic Fibrosis

United States, France, Belgium, Canada, Argentina, Germany, Netherlands
Vir Biotechnology, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); HIV Vaccine...

Recruiting

To Investigate Safety, Reactogenicity and Immunogenicity of VIR-1388 Compared With Placebo in Participants Without HIV

HIV I Infection

United States, South Africa
University Hospital, Ghent
CAS Medical Systems, Inc.; Belgian Foundation for Cardiac Surgery

Completed

Relation Between Mixed Venous Oxygen Saturation and Cerebral Oxygen Saturation Measured by Absolute and Relative Near-infrared Spectroscopy During Off-pump Coronary Artery Bypass Grafting.

Elective Off-pump Coronary Artery Bypass Grafting

Belgium
Medicines for Malaria Venture
Sanaria Inc.; Institute of Tropical Medicine, Belgium; Iqvia Pty Ltd; SGS Life... and other collaborators

Completed

Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites

Protozoan Infections | Parasitemia | Malaria,Falciparum | Parasitic Disease

Belgium
Cliniques universitaires Saint-Luc- Université...
Belgian Study Group for Pediatric Endocrinology

Unknown

Long-term Outcome of GnRH Analogues Treatment of Children With Idiopathic Central Precocious Puberty

Puberty, Precocious | Adiposity

Belgium
Medicines for Malaria Venture
Washington University School of Medicine; Sanaria Inc.; Institute of Tropical... and other collaborators

Completed

Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model

Malaria

Belgium
Cliniques universitaires Saint-Luc- Université...
Fondation Saint Luc; Fonds pour la recherche scientifique médicale (FRSM),... and other collaborators

Completed

Effect of Rehabilitation of Patients With a Central Nervous System Lesion

Stroke

Belgium
University Hospital, Ghent
Universitaire Ziekenhuizen KU Leuven; University Hospital, Antwerp; Cliniques... and other collaborators

Recruiting

Serum GLYcomics to Predict Graft Loss and Mortality After Liver Transplantation (GLYGALT)

Liver Transplant Failure | Prognostic Biomarkers

Belgium
Erasme University Hospital
Jules Bordet Institute; University Hospital St Luc, Brussels; Belgian Group of...

Recruiting

Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma (STEREOPAC)

Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Adenocarcinoma | Pancreatic Neoplasm

Belgium
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Treating Non-typhoidal Salmonella Bloodstream Infections in Children Under Five in DR Congo: a Cohort Study (TreNTS)

Blood-stream Infections | Salmonella Infection Non-Typhoid

Congo, The Democratic Republic of the
Seagen Inc.
Gynecologic Oncology Group; European Network of Gynaecological Oncological... and other collaborators

Completed

A Trial of Tisotumab Vedotin in Cervical Cancer

Cervical Cancer

Belgium, Spain, United States, Denmark, Italy, Germany, Czechia, Sweden
Evidation Health
Eli Lilly and Company; United States Department of Defense; Bill and Melinda... and other collaborators

Completed

A Virtual Prospective Study Exploring Activity Trackers and COVID-19 Infections

Covid19 | SARS-CoV Infection

United States
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in Children (DeNTS)

Bloodstream Infection | Malaria,Falciparum | Severe Malaria | Salmonella Bacteremia

Belgium

Clinical Trials Sponsored by VLIR-IUC, Belgium

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belarus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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