Search clinical trials for: フェーズ1

Total 48313 results

Saniona

Completed

A Study to Examine the Effect of Tesofensine and Metoprolol on the 24-hour Mean Heart Rate

Phase 1

Germany
Calliditas Therapeutics AB
Eurofins Optimed; York Bioanalytical Solution

Completed

Comparison of the Relative Oral Bioavailability of GKT137831 Formulated in Capsules or in Tablets

Phase 1

France
Calliditas Therapeutics AB

Completed

Study to Evaluate the Pharmacokinetics and Drug-Drug Interactions of Setanaxib in Healthy Adult Male and Female Subjects

Phase 1

France
JKT Biopharma Co., Ltd.

Recruiting

The Safety, Tolerability, Pharmacokinetics and Food Effects of SHEN211 Tablet in Healthy Subjects

Phase 1

China
Graviton Bioscience Corporation

Completed

Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects

Phase 1

United States
Alvotech Swiss AG

Completed

PK, Safety and Tolerability Study of AVT02 (Adalimumab) Pre-filled Syringe (PFS) vs, AVT02 Autoinjector (AI)

Phase 1

New Zealand
Pfizer

Completed

A Study to Determine the Effects of PF-04965842 on Midazolam PK in Healthy Volunteers

Phase 1

Belgium
Astellas Pharma Europe B.V.

Completed

A Study to Compare How Much Solifenacin Succinate and Mirabegron Reach the Blood When Administered Together as Fixed-dose Combination Tablets and With Single Individual Tablets of the Same Medications at Three Dose Levels

Healthy Subjects | Bioavailability | Phase 1

Germany
Daewoong Pharmaceutical Co. LTD.

Completed

Evaluate the Pharmacokinetics and Safety of DWP14012 Tablet A and Compare Those of DWP14012 Tablet B in Healthy Subjects

Phase 1 Study, Healthy Volunteers

Korea, Republic of
Handok Inc.
CMG Pharmaceutical Co. Ltd

Completed

A Phase 1 Study of NOV1601(CHC2014) in Adult Subjects With Solid Organ Malignancies

Solid Tumor, Adult | Phase 1

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.
Shanghai Haini Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study to Investigate the Mass Balance and Biotransformation of [14C]DWP14012 in Healthy Chinese Male Subjects

Phase 1 Study, Healthy Volunteers

China
Sintetica SA
Cross S.A.

Completed

Dose-finding Study of Intrathecal Paracetamol Administered Immediately Before Spinal Anaesthesia

Phase 1: Pain Management | Phase 2: Pain Management

Switzerland
Cinnagen

Completed

A Study Of CinnoRA (Adalimumab-CinnaGen) And Adalimumab (Humira) In Healthy Subjects

Bioequivalence | Phase 1

Iran, Islamic Republic of
Gem Pharmaceuticals

Completed

Safety Study of GPX-150 in Patients With Solid Tumors

Advanced Solid Tumors - Phase 1 Population

United States
Pfizer

Completed

A Study In Healthy People Of Multiple Doses Of UK-396,082 Given By Mouth, To Investigate The Safety, Toleration And Time Course Of Blood Concentration Of UK-396,082 And Its Effects.

Safety | Pharmacokinetic | Phase 1 | Multiple Dose | Toleration

Belgium
AryoGen Pharmed Co.

Completed

Pharmacokinetic, Safety and Tolerability Study of Altebrel in Healthy Male Subjects

Bioequivalence | Phase 1

Iran, Islamic Republic of
Janssen Research & Development, LLC

Completed

A Study of JNJ-40346527 in Patients With Relapsed or Refractory Hodgkin Lymphoma

Relapsed or Refractory Hodgkin Lymphoma

France, Germany
Duke University
National Institute of Mental Health (NIMH)

Completed

CAMPUS - Feasibility Sub-Study (CAMPUS-Feas)

Suicide

United States
University of Minnesota
Arizona State University

Completed

SMART Optimization of a Parenting Program for Active-duty Families (SMART)

Parenting

United States
Shenzhen Precision Health Food Technology Co. Ltd...

Completed

The Efficacy of White Kidney Bean on Oral Glucose Tolerance Test

Diabetes | Sugar; Blood, High

China
University of Aberdeen

Terminated

Focus on Fibre Study

Appetitive Behavior

United Kingdom
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA)

Completed

Nudges and Incentives to Enhance the Opioid Treatment Workforce

Opioid Abuse (Disorder)

United States
Epizyme, Inc.

Completed

Study of Tazemetostat as Single Agent in Solid Tumors or B-cell Lymphomas and in Combination With Prednisolone in DLBCL

B-cell Lymphomas (Phase 1) | Advanced Solid Tumors (Phase 1) | Diffuse Large B-cell Lymphoma (Phase 2) | Follicular Lymphoma (Phase 2) | Transformed Follicular Lymphoma | Primary Mediastinal Large B-Cell Lymphoma

Australia, Canada, France, Germany, Italy, Poland, Taiwan, Ukraine, United Kingdom, United States
Brigham and Women's Hospital

Withdrawn

Lung Irradiation for COVID-19 Pneumonia

SARS-CoV 2

United States
enGene, Inc.

Recruiting

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Superficial Bladder Cancer | Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

United States
University of California, Davis
National Institute of Mental Health (NIMH)

Terminated

Reducing Duration of Untreated Psychosis Through Rapid Identification and Engagement (DUP)

Psychotic Disorders

United States
Yooyoung Pharmaceutical Co., Ltd.

Active, not recruiting

Phase 1 to Evaluate the Safety and Pharmacokinetic Characteristics of Fixed-dose Combination of YYC506

Dyslipidemias

Korea, Republic of
Johnson & Johnson Pharmaceutical Research & Development...
Janssen Pharmaceutica N.V., Belgium

Completed

A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.

Pharmacokinetics | Advanced Malignancies | Solid Malignancies | Protein Kinase Inhibitors | Maximum Tolerated Dose | Antineoplastic Protocols | Clinical Trial, Phase 1
Factors Group of Nutritional Companies Inc.
Isura

Completed

Metabolic Differences Between Dihydroberberine and Micellar Berberine

Phase I and Phase II Metabolites of Berberine

Canada
Centre Hospitalier Universitaire Dijon

Recruiting

Patient-caregiver Collaboration for Better Cardiovascular Care for Patients With Long-term Mental Disorders: Multicentre Qualitative and Feasibility Studies (COPsyCAT)

Long-term Mental Disorders

France
Aragon Pharmaceuticals, Inc.

Active, not recruiting

Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)

Prostate Cancer

United States
Olivier Hugli
University of Lausanne Hospitals

Completed

Discomfort During Intravenous Cannulation in an Emergency Department: Impact of Communication (DOUCIP)

Pain, Acute | Catheterization, Peripheral

Switzerland
Boston Scientific Corporation

Active, not recruiting

A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation (ADVANTAGE AF)

Persistent Atrial Fibrillation

United States, Belgium, Canada, Spain
University of Thessaly

Completed

High Intensity Interval Circuit Training on Resting Metabolic Rate in Overweight Adults

Overweight and Obesity

Greece
Abbott Nutrition

Completed

Tolerance of Healthy Infants Fed Infant Formulas

Gastrointestinal Tolerance

United States
Government of Newfoundland and Labrador

Active, not recruiting

JASPER Implementation in NFLD

Autism Spectrum Disorder

Canada
Riphah International University

Completed

Phase 1 Cardiac Rehabilitation With and Without Lower Limb Paddling Effects in Post CABG Patients.

Coronary Artery Disease

Pakistan
Sqy Therapeutics
Biotrial

Recruiting

Phase 1/2a for Safety, PK and PD of SQY51 in Paediatric and Adult Patients Duchenne Muscular Dystrophy (AVANCE1)

Duchenne Muscular Dystrophy

France
University of Minnesota
University of California, San Francisco; Posit Science Corporation

Completed

D2D Normative Data for Remote Assessments

Cognition

United States
Brigham and Women's Hospital
University of Pennsylvania; Breast Cancer Research Foundation; Ministry of Health... and other collaborators

Completed

Promoting Early Detection of Breast Cancer in Rural Rwanda: Impact of Community Health Worker and Nurse Training (BCED)

Breast Cancer
AstraZeneca

Active, not recruiting

MEDI5752 in Japanese Patients With Advanced Solid Tumors.

Advanced Solid Tumors

Japan
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Unknown

Phase I Trial to Investigate Cafusertib Hydrochloride in Combination With Low Dose Cytarabine in Chinese Patients With Acute Myeloid Leukaemia (AML)

Leukemia, Myeloid, Acute

China
Pfizer

Completed

Pharmacokinetics, Safety and Tolerability Study of PF-03463275 in Healthy Male Japanese and Western Subjects

Healthy

United States
Pfizer

Completed

First In Human Study Of Increasing Oral Doses Of PF-04634817

Healthy

United States
University Hospitals of Derby and Burton NHS Foundation...
University of Nottingham; National Institute for Health Research, United Kingdom and other collaborators

Completed

The POP-ACLR Study (POP-ACLR)

Anterior Cruciate Ligament Injuries | Anterior Cruciate Ligament Rupture | Rehabilitation

United Kingdom
Novavax
Coalition for Epidemic Preparedness Innovations

Completed

Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant

COVID-19

United States, Australia
Drexel University
Esperanza Health Center; The Philadelphia AIDS Consortium

Recruiting

CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos

Anxiety Disorders | Post Traumatic Stress Disorder | Depression, Unipolar

United States
Pfizer

Completed

A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.

Pharmacokinetics | Safety | Phase 1 | Single Dose | Toleration

Belgium
Hospices Civils de Lyon

Completed

Development of a Quality of Life Measurement Scale in Hereditary Haemorrhagic Telangiectasia (HHT) Disease. (ELECT-RO)

Hereditary Hemorrhagic Telangiectasia

France
University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom

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