Search clinical trials for: ALK,

Total 486 results

ALK-Abelló A/S
Quantify Research

Active, not recruiting

Comparative Real World Effectiveness of SQ Sublingual Immunotherapy (SLIT)-Tablets vs. Controls in Allergic Rhinitis and Asthma

Asthma | Allergy | Allergic Rhinitis

Denmark
ALK-Abelló A/S

Completed

A Dose-response Evaluation of ALK (the Sponsor) Tree Allergy Immunotherapy Tablet

Birch Pollen Allergy

Finland, Netherlands
ALK-Abelló A/S
Ernst & Young

Recruiting

The Effect of Allergic Rhinitis on Educational Outcomes

Allergic Rhinitis

Denmark
ALK-Abelló A/S

Completed

Impact of AIT on Allergic Rhinitis and Asthma

Allergy | Respiratory Disease

Denmark
ALK-Abelló A/S
Ergomed; ACM Pivotal Global Central Laboratory

Completed

House Dust Mite Treatment of Asthma. The MITRA Trial House Dust Mite Treatment of Asthma (MITRA)

Asthma

Germany
Karolinska Institutet
Karolinska University Hospital; Skane University Hospital

Completed

Safety and Efficacy Study of Intralymphatic Allergen-specific Immunotherapy

Allergic Rhinitis

Sweden
Instituto Nacional de Cancerologia de Mexico

Completed

Clinicopathological Features of NSCLC Patients Associated With the Chromosome 2p (EML4-ALK) (ALK)

Non Small-cell Lung Cancer

Mexico
Karolinska Institutet

Completed

The Safety and Efficacy of Intralymphatic Immunotherapy in Pollen Allergic Adolescents and Young Adults With Asthma

Asthma | Allergy | Rhinitis
Karolinska Institutet
Karolinska University Hospital; Skane University Hospital; Sodra Alvsborgs Hospital

Completed

Intralymphatic Immunotherapy in Increasing Doses, After Subcutaneous Immunotherapy

Rhinitis, Allergic

Sweden
Bispebjerg Hospital
ALK-Abelló A/S

Completed

Immunological Comparison of AIT and SCIT Immunotherapy Against Grass Pollen

Allergic Rhinitis Due to Grass Pollens

Denmark
ALK-Abelló A/S

Completed

A Phase III Trial Assessing the Pharmacodynamic Effect and the Tolerability of Grazax Treatment

Grass Pollen Allergy

Denmark
Lars Olaf Cardell

Completed

Is Intralymphatic Allergen Immunotherapy Effective and Safe?

Allergic Rhinitis Due to Grass Pollen

Sweden
The S.N. Fyodorov Eye Microsurgery State Institution

Completed

Femtosecond Laser-assisted Anterior Lamellar Keratoplasty

Corneal Opacity | Keratoconus
ALK-Abelló A/S

Completed

Tolerability of Grazax-R in Children

Allergy

Germany
ALK-Abelló A/S

Completed

Tolerability of ALK Grass Tablet in Children

Allergy

Spain
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Study of Exosome EML4-ALK Fusion in NSCLC Clinical Diagnosis and Dynamic Monitoring

Untreated Advanced NSCLC Patients | FISH Identified ALK Fusion Positive or Negative

China
ALK-Abelló A/S

Completed

A Trial of the ALK Grass Tablet in Subjects With Hayfever

Allergy

Denmark
ALK-Abelló A/S

Completed

Changes in the Immune Response and Skin Reactivity of Grass Pollen Allergic Patients Treated With ALK Grass Tablets

Allergy

Spain
UMC Utrecht
Dr. F.P. Fischer-stichting, Utrecht, The Netherlands

Terminated

PENTACON Trial: Partial ENdothelial Trepanation in Addition to Anterior Lamellar Keratoplasty in keratoCONus (PENTACON)

Keratoconus

Netherlands
ALK-Abelló A/S

Completed

Efficacy and Safety Trial of the ALK HDM Tablet in House Dust Mite Allergic Subjects

Asthma

Denmark
Lars Olaf Cardell

Completed

Follow up Study 5-6 Years After ILIT With 2 Concomitant Allergens, Birch and Grass

Allergic Rhinitis

Sweden
Alkermes, Inc.

Completed

Pharmacokinetics and Safety of ALKS 5461 in Healthy Subjects and Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

United States
National Jewish Health
ALK-Abelló A/S

Completed

Dog Hair Extract Study

Potency of Dog Hair Extract

United States
ALK-Abelló A/S

Completed

Safety of ALK Ragweed Tablet

Allergy

United States
Karolinska Institutet
Karolinska University Hospital; Skane University Hospital

Completed

Intralymphatic Immunotherapy in Increasing Doses, Substudy

Rhinitis, Allergic, Seasonal

Sweden
Harbin Medical University

Completed

Therapeutic Effect of Crizotinib for Rearrangement-negative, High Phosphorylated ALK Patients

ALK Phosphorylation

China
Alkermes, Inc.

Terminated

Phase 1 ALKS 1140 in Healthy Adults

Central Nervous System Diseases

Australia
Betta Pharmaceuticals Co., Ltd.

Unknown

The Absorption, Metabolism and Excretion of [14C]Ensartinib in Human

ALK-POSITIVE NSCLC

China
Abbott
Datamap; Linical Co., Ltd.

Completed

A Study Investigating the Immunologic Effects and Safety of 60-day Treatment of the ALK HDM Tablets in Adult Subjects With HDM-Induced Allergic Rhinitis and/or Atopic Asthma

Asthma | Allergy | Rhinitis

Belarus, Russian Federation
Centre Hospitalier Universitaire de Nice

Completed

Multicenter Validation of the Sensitivity of Theranostic ALK Rearrangement Detection by FISH Analysis and Prevalence of Escaping Mutations in Circulating Tumor Cells for the Non-invasive Management of Lung Cancer Patients (STALKLUNG01)

Lung Neoplasms

France
Novartis Pharmaceuticals

Recruiting

Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study

ALK Positive Malignancies

Germany, France, Australia, Belgium, Italy, Korea, Republic of, Poland, China, United States, Taiwan, Brazil, Bulgaria, Hong Kong, Japan, Lebanon, Malaysia, Spain, Russian Federation, Colombia, Singapore, Czechia
ALK-Abelló A/S

Completed

Efficacy and Safety Trial of ALK-depot SQ Mites in Subjects With Atopic Dermatitis

Atopic Dermatitis

Germany
Aarhus University Hospital
University of Aarhus; University Hospital, Linkoeping

Active, not recruiting

Documentation of Efficacy of Intralymphatic Allergen Immunotherapy (ILITNU)

Allergic Rhinitis Due to Grass Pollen | Allergic Asthma | Allergic Conjunctivitis of Both Eyes

Denmark, Sweden
Takeda

Completed

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

Carcinoma, Advanced ALK+ or ROS1+Non-Small-Cell Lung, Neoplasm, Advanced ALK+ or ROS1+Solid Tumors

Spain, Italy, Netherlands, France
Ludwig Institute for Cancer Research
Xcovery Holding Company, LLC; Cancer Research Institute, New York City; MedImmune...

Completed

Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer

Carcinoma | NSCLC | Non-small Cell Lung Cancer

United States
University of Aarhus

Completed

Effect of Intralymphatic Immunotherapy

Allergy | Immune Tolerance | Injection Site Discomfort

Denmark
ASST Fatebenefratelli Sacco
ALK-Abelló A/S

Completed

Comparison of the Efficacy and the Safety of Different Schedules of Administration of Sub-lingual Immunotherapy

Pollen Allergy

Italy
University of Milano Bicocca

Completed

Pilot Study of Crizotinib in Relapsed ALK+ Lymphomas

Anaplastic Large Cell Lymphoma, ALK-Positive

Italy
Hoffmann-La Roche

No longer available

Expanded Access to Entrectinib for Cancers With NTRK1/2/3, ROS1, or ALK Gene Fusions

Cancers With NTRK, ROS1, or ALK Gene Fusions

United States
Naestved Hospital

Recruiting

Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study.

Non-small Cell Lung Cancer | Malignant Pleural Effusion

Denmark
Li Zhang, MD

Recruiting

Ensatinib Treat Second-generation ALK-TKI Resistance After Second-generation ALK-TKI Resistance (ERSGATR)

The Diagnosis Was ALK Positive NSCLC | Second Generation ALK-TKI is Resistant | Efficacy of Ensatinib in This Subset of Patients

China
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of LEE011 and Ceritinib in Patients With ALK-positive Non-small Cell Lung Cancer.

Non-small Cell Lung Cancer

Taiwan, Spain, Italy, United States, Korea, Republic of, France
Novartis Pharmaceuticals

Completed

LDK378 in Adult Chinese Patients With ALK-rearranged (ALK-positive) Advanced Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib

Non-Small Cell Lung Cancer

China
ALK-Abelló A/S

Completed

Assessment of Grazax® Treatment Compliance

Allergy

Austria
Pfizer

Completed

Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)

Non-Small Cell Lung Cancer

Spain
Shanghai Fosun Pharmaceutical Industrial Development...

Recruiting

A Phase I/II Clinical Study of SAF-189s in Non-small Cell Lung Cancer (NSCLC) Patients

Advanced Solid Tumor | Advanced Cancer | Lung Cancer, Nonsmall Cell

China
British Columbia Cancer Agency
Insight Genetics

Completed

Comparison of qPCR to IHC and FISH for Detection of ALK Fusion Mutations in FFPE Tissue From NSCLC Patients (PCRTALK)

Nonsmall Cell Lung Cancer

Canada
Hunan Province Tumor Hospital

Completed

ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Pure Squamous Cell Carcinoma

Non-small Cell Lung Cancer

China
Memorial Sloan Kettering Cancer Center
Xcovery Holding Company, LLC

Active, not recruiting

Treating Patients With Melanoma and ALK Alterations With Ensartinib

Melanoma

United States
Instituto Nacional de Cancerologia de Mexico

Unknown

ALK Rearrangements in Lung Adenocarcinoma: Epidemiology in Latin America (CLICaP)

Lung Cancer

Mexico

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