Search clinical trials for: Allergen challenge

Total 1790 results

Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Development of a Novel Non-invasive Inflammometry Following Allergen Challenge in Patients With Mild Allergic Asthma

Mild Allergic Asthma

Germany
Karolinska Institutet

Recruiting

Nasal Allergen Challenge Test as a Method to Detect Clinical Reactivity Against Birch Pollen (NAC)

Allergic Rhinitis Due to Pollen

Sweden
Allergy & Asthma Medical Group & Research Center

Not yet recruiting

Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge

Allergy to Cats
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

HDM and Silver Birch NAC Standardisation

Allergic Rhinitis

United Kingdom
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Medical University of Vienna

Recruiting

Contribution of Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Upon Nasal Allergen Contact

Allergy

Austria
Lithuanian University of Health Sciences

Recruiting

Non-coding RNAs Analysis of Eosinophil Subtypes in Asthma

Allergic Asthma | Severe Eosinophilic Asthma

Lithuania
Benjamin Medoff
National Institutes of Health (NIH); U.S. Army Medical Research and Development...

Recruiting

Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

Asthma

United States
Bausch & Lomb Incorporated

Completed

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis.

Allergic Conjunctivitis

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; Novartis Pharmaceuticals; Rho Federal Systems Division, Inc.

Active, not recruiting

Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants (OUtMATCH)

Peanut Allergy | Multi-food Allergy

United States
University of British Columbia
Networks of Centres of Excellence of Canada; Allergy, Genes and Environment...

Completed

Genetics of the Early and Late Response to Allergen Challenge

Asthma | Allergic Rhinitis

Canada
University Hospital, Geneva

Terminated

Study to Assess Tolerance of Traces in Peanut/Tree Nut Allergic Children.

Peanut Allergy | Food Allergy | Tree Nut Allergy

Switzerland
Imperial College London
Novartis Pharmaceuticals

Completed

Repeat Nasal Allergen Challenge

Hayfever

United Kingdom
JOSALYN CHO
Massachusetts General Hospital

Active, not recruiting

Airway Immune Response to Allergens (Use Lay Language Here)

Allergic Rhinitis | Allergic Conjunctivitis | Allergic Asthma | Allergy to Cats | Allergy to Dust Mites

United States
Senju USA, Inc.

Completed

Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis

Allergic Conjunctivitis

United States
National Institute of Allergy and Infectious Diseases...
Regeneron Pharmaceuticals; PPD; Rho Federal Systems Division, Inc.; ALK-Abelló A/S and other collaborators

Active, not recruiting

Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction (GRADUATE)

Grass Pollen Allergy | Allergic Rhinoconjunctivitis

United Kingdom
The Cleveland Clinic

Enrolling by invitation

Asthma Inflammation Research (AIR)

Asthma | Allergic Asthma | Non-allergic Asthma

United States
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Inner-City Asthma Consortium

Completed

Cockroach Immunotherapy in Children and Adolescents (CRITICAL)

Persistent Asthma

United States
University of Southampton

Completed

Effect of Clopidogrel on Allergen Challenge in Asthma

Asthma

United Kingdom
Revolo Biotherapeutics

Completed

Allergen Challenge Trial of IRL201104 in Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

United Kingdom
Faes Farma, S.A.
ORA, Inc.

Completed

A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model.

Allergic Conjunctivitis

United States
Johann Wolfgang Goethe University Hospital

Completed

Safety of Bronchial Allergen Challenge and Predictors for Positive Reaction.

House Dust Mite Allergy | Bronchial Hyperresponsiveness

Germany
Aldeyra Therapeutics, Inc.

Completed

A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)

Atopic Asthma

Canada
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Screening Inhaled Allergen Challenge for Dermatophagoides Farinae (MiteScreen)

Asthma

United States
Marinomed Biotech AG

Completed

Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis

Allergic Rhinitis | Allergic Conjunctivitis

Austria
Prescott Woodruff
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study of the Inflammation and Airway Changes That Occur After Exposure to Allergen in Asthmatics (ACE)

Asthma

United States
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions (SIMBA)

Allergic Rhinitis

Germany
Organon and Co

Completed

A Study of the Effects of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms (Study P04209)

Conjunctivitis, Allergic
Tetherex Pharmaceuticals Corporation

Completed

Study to Assess the Safety and Efficacy of SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and in Subjects With Chronic Obstructive Pulmonary Disease (Part 2)

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Polish Lymphoma Research Group

Completed

Ofatumumab With IVAC Salvage Chemotherapy in Diffuse Large B Cell Lymphoma Patients (PLRG8)

Diffuse Large B Cell Lymphoma

Poland
Teva Branded Pharmaceutical Products R&D, Inc.
AllerGen NCE Inc.

Completed

Efficacy/Safety Study of Nebulized IVX-0142, a Novel Antiallergic Drug, in Mild Allergic Asthma

Asthma

Canada
Imperial College London

Completed

Standardising Nasal Allergen Challenge in Adult With Hay Fever

Allergic Rhinitis

United Kingdom
Regeneron Pharmaceuticals

Completed

Study in Cat-Allergic Patients With Asthma to Evaluate the Efficacy of a Single Dose of REGN1908-1909 to Reduce Bronchoconstriction Upon Cat Allergen Challenge

Cat Allergy | Mild Asthma

France
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers. (Mitey Nose)

Healthy Participants | Tobacco Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation (LateAna)

Asthma
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model (Kitty Nose)

Tobacco Smoking | Healthy Participants | E-cigarette Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation (EarlyAna)

Asthma
Christina West
Nutricia, Inc.; The Västerbotten county council; State Government founding for... and other collaborators

Completed

New Validated Recipes for Double-blind Placebo-controlled Low Dose Food Challenges

Allergy

Sweden
SecuraBio

Completed

A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic Subjects

Asthma

Germany, United Kingdom
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

AsthMatic Inflammation and Neurocircuitry Activation (MINA) (MINA)

Allergic Asthma

United States
Alyatec

Completed

Clinical Validation Study in Allergic Conjunctivitis to Birch Pollen During Allergen Challenge in ALYATEC EEC

Allergic Conjunctivitis

France
University of Zurich
ADR-AC Laboratory, Berne

Completed

Basophile Activation Testing (BAT) in Hazelnut Allergy (Hazelnut BAT Study)

Food Allergy

Switzerland
AstraZeneca
Parexel

Withdrawn

A Study to Evaluate the Effect of AZD8154 Administered Via Nebulizer Once Daily in Subjects With Mild Allergic Asthma Challenged With an Inhaled Allergen

Asthma

Canada
Bausch & Lomb Incorporated

Completed

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Acute Allergic Conjunctivitis.

Allergic Conjunctivitis

United States
Marinomed Biotech AG

Completed

Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray

Allergic Rhinitis | Allergic Conjunctivitis | Hayfever

Austria
Lithuanian University of Health Sciences
University of Groningen; Research Council of Lithuania

Unknown

Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma (ECMA)

Extracellular Matrix Alteration | Allergic Asthma | Airway Remodelling

Lithuania
King's College London
Guy's and St Thomas' NHS Foundation Trust

Unknown

Basophil Activation Test to Diagnose Food Allergy (BAT2)

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
ORA, Inc.

Completed

Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model

Allergic Conjunctivitis

United States
McMaster University
AllerGen NCE Inc.

Unknown

Canadian Peanut Thresholds Study

Peanut Allergy

Canada
Lithuanian University of Health Sciences
University of Groningen; Research Council of Lithuania

Completed

Eosinophil Induced Remodelling in Asthma (ERA)

Allergic Asthma | Airway Remodelling

Lithuania

Search clinical trials for: Allergen challenge

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