Search clinical trials for: Allogeneic, Off-The-Shelf T-cell Immunotherapy

Total 5328 results

Corregene Biotechnology Co., Ltd

Not yet recruiting

CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers

Cervical Cancer | Anal Cancer | Head and Neck Cancers | Other Solid Tumors
Theravectys S.A.

Not yet recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Guangzhou FineImmune Biotechnology Co., LTD.

Recruiting

Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors (TAL-T)

Advanced Solid Tumor | Immunotherapy | Tumor Associated Lymph Node T Cell

China
Queensland Institute of Medical Research
Merck Sharp & Dohme LLC; Royal Brisbane and Women's Hospital; Princess Alexandra... and other collaborators

Recruiting

T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma (TCaP)

Glioblastoma Multiforme | Astrocytoma, Grade IV

Australia
Ryan Stephenson

Recruiting

Naltrexone and Propranolol Combined With Immunotherapy

Advanced Melanoma

United States
Neogap Therapeutics AB
Karolinska University Hospital; CTC Clinical Trial Consultants AB; Region Västmanland and other collaborators

Recruiting

A First-In-Human Trial of pTTL in Advanced Colorectal Cancer

Colorectal Cancer

Sweden
IGM Biosciences, Inc.

Recruiting

Evaluation of IGM-2644 in Adults With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States
Zhao Jun

Recruiting

Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients

Esophageal Cancer | Lung Cancer

China
Christian Hinrichs

Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical Cancer | HPV-Related Malignancy | Metastatic Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
Christian Hinrichs
National Cancer Institute (NCI)

Not yet recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical Cancer | HPV-Related Malignancy | Vulvar Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Associated Cervical Carcinoma | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
Marengo Therapeutics, Inc.

Recruiting

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors (START-001)

Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Epstein-Barr Virus Infections | Advanced Solid Tumors | Vulvar Neoplasms | Vulvar Diseases | Abdominal Neoplasm | Lung Neoplasm | Papillomavirus Infection | Genital Neoplasm, Female

United States, Canada
Christian Hinrichs
National Cancer Institute (NCI); Cancer Immunology and Metabolism Center of...

Recruiting

KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer

Cervical Cancer | Breast Cancer | Gastric Cancer | Lung Cancer

United States
The Affiliated Hospital of Xuzhou Medical University
Xuzhou Medical University

Recruiting

Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer

Immunotherapy

China
AstraZeneca
Parexel

Recruiting

Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Relapsed or Refractory Classical Hodgkin Lymphoma

Italy, United States, Spain, United Kingdom, Canada, Denmark, France, China, Germany
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Kita-kyushu Lung Cancer Antigen 1, Human

United States
New York Medical College

Recruiting

Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T-Cell ALL & Lymphoma (ALLO-T-DART)

T-cell Acute Lymphoblastic Leukemia | T-Cell Acute Lymphoblastic Lymphoma

United States
The Affiliated Hospital of Xuzhou Medical University
Xuzhou Medical University

Recruiting

Clinical Study of CAIX-targeted CAR-T Cells in the Treatment of Advanced Renal Cell Carcinoma

Immunotherapy

China
ImmunoVaccine Technologies, Inc. (IMV Inc.)
Merck Sharp & Dohme LLC

Recruiting

DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (VITALIZE)

Relapsed Diffuse Large B-cell Lymphoma | Refractory Diffuse Large B-cell Lymphoma

Australia, Spain, United States, France, Hungary, New Zealand, Poland, Serbia, Canada, Romania
Eureka Therapeutics Inc.

Recruiting

T-Cell Therapy (ECT204) in Adults With Advanced HCC (ARYA-3)

Hepatocellular Carcinoma | Liver Neoplasm | Metastatic Liver Cancer | Liver Cancer, Adult

United States
Vaccinex Inc.
Merck Sharp & Dohme LLC

Recruiting

Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (KEYNOTE-B84)

Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)

United States
Adicet Bio, Inc

Recruiting

A Phase 1 Study of ADI-001 in B Cell Malignancies (GLEAN-1)

Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma

United States
Institute of Hematology & Blood Diseases Hospital
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Beijing...

Recruiting

Allogeneic γδ T Cells Immunotherapy in r/r Non-Hodgkin's Lymphoma (NHL) or Peripheral T Cell Lymphomas (PTCL) Patients

Non-Hodgkin's Lymphoma (NHL) | Peripheral T Cell Lymphoma (PTCL)

China
Rong Tao

Recruiting

Camrelizumab, Pegaspargase and Apatinib With Radiation Therapy for Stage IE/IIE ENKTL

Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

China
Theodore S. Johnson
National Cancer Institute (NCI); Emory University; Augusta University

Recruiting

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Glioblastoma | Ependymoma | Medulloblastoma | Diffuse Intrinsic Pontine Glioma

United States
Second Affiliated Hospital of Guangzhou Medical...
Hunan Zhaotai Yongren Medical Innovation Co. Ltd.

Recruiting

Induced-T Cell Like NK Cellular Immunotherapy for Cancer Lack of MHC-I

Anti-cancer Cell Immunotherapy | T Cell and NK Cell

China
Herbert Lyerly

Recruiting

Assessing the Immunogenicity of pING-hHER3FL

Advanced Cancer

United States
Immatics US, Inc.

Recruiting

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors (ACTengine)

Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer

United States, Germany
Medeor Therapeutics, Inc.

Not yet recruiting

Cellular Immunotherapy for Immune Tolerance in Past Recipients of HLA Zero-mismatch, Living Donor Kidney Transplants

Kidney Transplant Rejection
National Cancer Institute (NCI)

Recruiting

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers

Metastatic Solid Tumors | Treatment-Refractory Cancers

United States
National Heart, Lung, and Blood Institute (NHLBI)
Loyola University Medical Center (LUMC)

Recruiting

HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Kidney Cancer

United States
Second Affiliated Hospital of Guangzhou Medical...
First Affiliated Hospital, Sun Yat-Sen University; Guangdong Zhaotai InVivo... and other collaborators

Recruiting

GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression

Hepatocellular Carcinoma | CAR | Immunotherapy | Squamous Cell Lung Cancer | GPC3 Gene Inactivation | T Cell

China
Mari Dallas

Recruiting

T Cell Therapy of Opportunistic Cytomegalovirus Infection

Cytomegalovirus Infections | Opportunistic Infections | Hematopoietic Stem Cell Transplant

United States
Centre Leon Berard
National Cancer Institute, France

Recruiting

Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment (MOST plus)

Malignant Solid Neoplasms

France
Instil Bio

Terminated

ITIL-168 in Advanced Melanoma (DELTA-1)

Advanced Cutaneous Melanoma

United States, Canada, United Kingdom
Eureka Therapeutics Inc.

Terminated

Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1)

Hepatocellular Carcinoma | Liver Neoplasm | Liver Cancer | Metastatic Liver Cancer

United States
Herbert Lyerly
Merck Sharp & Dohme LLC

Active, not recruiting

A Study to Evaluate Concurrent VRP-HER2 Vaccination and Pembrolizumab for Patients With Breast Cancer

Breast Cancer | HER2+ Breast Cancer

United States
TILT Biotherapeutics Ltd.

Active, not recruiting

TNFalpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 During TIL Treatment of Advanced Melanoma (TUNINTIL)

Metastatic Melanoma

France, Denmark
Instil Bio

Active, not recruiting

ITIL-306 in Advanced Solid Tumors

Renal Cell Carcinoma | Epithelial Ovarian Cancer | Non-small Cell Lung Cancer

United States
Immatics US, Inc.
M.D. Anderson Cancer Center

Completed

ACTolog in Patients With Solid Cancers (ACTolog)

Cancer | Solid Tumor

United States
Immatics US, Inc.

Completed

TCR-engineered T Cells in Solid Tumors: IMA202-101 (ACTengine)

Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer

United States, Germany
Immatics US, Inc.

Completed

Human Leukocyte Antigen Typing and Tumor Antigen Expression Profiling

Neoplasms | Adult Solid Tumor | Refractory Cancer | Recurrent Cancer

United States
GlaxoSmithKline
Merck Sharp & Dohme LLC

Terminated

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Neoplasms

United States, Spain, Netherlands, United Kingdom, Canada
University of Wisconsin, Madison

Terminated

A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients

Cytomegalovirus Infections | Solid Organ Transplant

United States
Immatics US, Inc.

Completed

TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101) (ACTengine)

Cancer | Solid Tumor | Refractory Solid Tumors | Recurrent Solid Tumors

United States, Germany
H. Lee Moffitt Cancer Center and Research Institute

Active, not recruiting

Vemurafenib With Lymphodepletion Plus Adoptive Cell Transfer & High Dose IL-2 Metastatic Melanoma

Metastatic Melanoma

United States
Takara Bio Inc.

Completed

Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients With Synovial Sarcoma

Synovial Sarcoma

Japan
Myeloid Therapeutics

Suspended

A Study of MT-101 in Subjects With CD5+ Relapsed/Refractory TCL (IMAGINE)

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Lymphoma, T-Cell, Peripheral | Cell Therapy | Adoptive Cellular Immunotherapy

United States
Medeor Therapeutics, Inc.
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

Cellular Immunotherapy in Recipients of HLA-matched, Living Donor Kidney Transplants

Kidney Transplant Rejection

United States, Canada
ImmunoVaccine Technologies, Inc. (IMV Inc.)

Terminated

Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer (AVALON)

Platinum-resistant Epithelial Ovarian Cancer

United States, Canada, Puerto Rico
Alaunos Therapeutics

Active, not recruiting

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Cholangiocarcinoma | Adenocarcinoma of Lung | Endometrial Cancer | Non-small Cell Lung Cancer | Ovarian Carcinoma | Squamous Cell Lung Cancer | Ovary Neoplasm | Adenosquamous Cell Lung Cancer

United States

Search clinical trials for: Allogeneic, Off-The-Shelf T-cell Immunotherapy

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