Search clinical trials for: Anticholesteremic Agents

Total 187500 results

Baylor Breast Care Center

Active, not recruiting

Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer (SIMPHONY)

Breast Cancer Stage IV

United States
DICE Therapeutics, Inc., a wholly owned subsidiary...

Completed

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Healthy Participants

United States
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Atorvastatin Film-coated Tablets 40 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
University College, London
National Multiple Sclerosis Society

Completed

Simvastatin in Secondary Progressive Multiple Sclerosis (MS-OPT)

Secondary Progressive Multiple Sclerosis

United Kingdom
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Healthy

United States
Aligos Therapeutics

Active, not recruiting

A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Healthy Volunteers

United States
ViiV Healthcare

Completed

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

HIV Infections

United States
Tianjin Medical University Eye Hospital

Completed

Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic Dacryocystitis

Dacryocystorhinostomy | Fluorouracil | Hydroxybutyl Chitosan | Chronic Dacryocystitis

China
Massachusetts General Hospital
Dana-Farber Cancer Institute; Brigham and Women's Hospital

Completed

STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)

Heart Failure

United States, Canada
Minia University

Completed

Evaluation of Antimicrobial Efficacy and Postoperative Pain After Using Silver Nanoparticles and Chitosan Nanoparticles Against Enterococcus Faecalis and Candida Albicans Biofilm

Endodontic Disease

Egypt
AstraZeneca
Parexel

Completed

A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

Healthy Participants

United States
Northwestern University
Astellas Pharma US, Inc.

Terminated

Women With Chest Pain and Normal Coronary Arteries Study

Chest Pain

United States
Mayo Clinic
Merck Sharp & Dohme LLC

Completed

The Acute Effect of Statins on Inflammatory Markers of Athersclerotic Tissue

Carotid Artery Disease
University of Kansas Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Impact of Statin Therapy on Muscle Mitochondrial Function and Aerobic Capacity

Mitochondrial Diseases

United States
Obafemi Awolowo University Teaching Hospital
University Hospital Birmingham NHS Foundation Trust; Cures Within Reach

Completed

Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) (ATORTUB)

Tuberculosis | Tuberculosis, Pulmonary

United Kingdom, Nigeria
University of Kansas Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Active, not recruiting

Impact of Statin Therapy on Adaptations to Aerobic Exercise

Cardiovascular Diseases

United States
Medical University of South Carolina

Completed

DSAP Treatment Comparison: 2% Lovastatin/ 2% Cholesterol vs 2% Lovastatin Alone (DSAP)

Actinic Porokeratosis

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Withdrawn

Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia (MILOS-Spain)

Mixed Dyslipidemia | Primary Hypercholesterolemia
Pfizer

Completed

Study To Evaluate The Effect Of Two Steady State Doses of PF 06882961 On Rosuvastatin And Midazolam Pharmacokinetics In Otherwise Healthy Adult Participants With Obesity

Obesity

United States
Baylor College of Medicine
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome. (Merck-123)

Metabolic Syndrome

United States
Technical University of Munich

Terminated

Synaptic Plasticity and Cognitive Function in RASopathies (SynCoRAS)

Impaired Cognition | Impaired Synaptic Plasticity

Germany
Stanford University
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

PCSK9 Inhibition After Heart Transplantation

Vasculopathy

United States
Pauls Stradins Clinical University Hospital

Active, not recruiting

Impact of Optimal Pharmacotherapy on Lipid Profile and Qualitative Features of Atherosclerotic Plaques

Atherosclerotic Cardiovascular Disease

Latvia
Prince Sattam Bin Abdulaziz University

Active, not recruiting

Using Of Chitosan in Alveolar Ridge Preservation

Bone Augmentation | Tooth Extraction Status Nos

Saudi Arabia
Aristotle University Of Thessaloniki

Completed

Treatment of Residual Pockets in Periodontal Patients Using an Oscillating Chitosan Device

Periodontitis

Greece
Annapoorna Kini

Completed

Effect of Evolocumab on Coronary Plaque Characteristics (YELLOW III)

Coronary Artery Disease

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

Overweight Subjects | Obese Subjects

China
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers

Healthy Volunteers

China
Novartis

Completed

Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatin

Hypertension | Dyslipidemia | Hypercholesterolemia

United States
Boehringer Ingelheim

Completed

DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)

Healthy

Germany
Boehringer Ingelheim

Completed

Transporter Cocktail Mutual Interaction

Healthy

Germany
Boehringer Ingelheim

Completed

This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men

Healthy

Germany
Lars Gullestad
Helsinki University Central Hospital; Aarhus University Hospital; Rigshospitalet... and other collaborators

Completed

Cholesterol Lowering With EVOLocumab to Prevent Cardiac Allograft Vasculopathy in De-novo Heart Transplant Recipients (EVOLVD)

Cardiac Allograft Vasculopathy

Denmark, Finland, Sweden
NYU Langone Health

Completed

CHOlesterol Lowering and Residual Risk in Type 2 Diabetes (CHORD)

Type 2 Diabetes

United States
Boehringer Ingelheim

Completed

Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin

Healthy

Germany
Pomeranian Medical University Szczecin

Completed

Statins in Patients With Spontaneous Intracerebral Hemorrhage

Intracerebral Hemorrhage

Poland
Mario Negri Institute for Pharmacological Research
Associazione Italiana per la Ricerca sul Cancro

Completed

Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer (YAPPETIZER)

Triple Negative Breast Cancer

Italy
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Terminated

Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia

Hypertension | Dyslipidemias

Georgia, Russian Federation, Ukraine
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endothelial Function in Obstructive Sleep Apnea

Obstructive Sleep Apnea of Adult

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pentoxifylline, Atorvastatin, and Vitamin E in Treating Patients With Erectile Dysfunction After Radiation Therapy for Prostate Cancer

Prostate Adenocarcinoma | Male Erectile Disorder | Impotence | Erectile Dysfunction, CTCAE

United States
Rawalpindi Medical College

Completed

Comparison Between Atorvastatin and Rosuvastatin in Reduction of Inflammatory Biomarkers in Patients With Acute Coronary Syndrome

Mi Q Wave

Pakistan
Pfizer

Terminated

A Drug-Drug Interaction Study to Estimate the Effect of PF-07081532 on the Pharmacokinetics of Dabigatran and Rosuvastatin in Overweight or Obese Adult Participants

Healthy

United States
Yasmine gamil

Completed

The Anti-fungal Effect of Miconazol Versus Miconazol-Loaded Chitosan Nanoparticles

Oral Thrush

Egypt
University of Chicago
Johns Hopkins University

Active, not recruiting

Atorvastatin Treatment of Cavernous Angiomas With Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial (AT CASH EPOC)

Cerebral Cavernous Malformation

United States
University of Nebraska

Completed

Effect of Locally-Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients

Periodontal Diseases

United States
Kyoto University
Juntendo University; Yamaguchi University Hospital

Completed

Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS)

Coronary Disease | Hypercholesterolemia

Japan
Instituto Mexicano del Seguro Social
Hospital Civil de Guadalajara

Completed

Tricalcium Phosphate and Chitosan as Bone Regenerator Versus Autologous Graft in Surgery for Mandibular Fracture

Mandibular Fractures

Mexico
University of Nebraska
Amgen

Completed

Impact of Evolocumab in Cardiac Transplant Patients With CAV

Heart Transplant

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants

Healthy

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Healthy Volunteers

United States

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