Search clinical trials for: Aphasia, Primary Progressive

Total 18313 results

Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive
University of Pennsylvania

Not yet recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Parkinson Disease | Alzheimer Disease | ALS | Polyneuropathies | Frontotemporal Dementia | Pheochromocytoma | Thoracic Aortic Aneurysm | Paraganglioma | Genetic Predisposition | Cardiomyopathy Non-ischemic
M.D. Anderson Cancer Center

Not yet recruiting

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

OligoProgressive Metastatic Disease

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
Milton S. Hershey Medical Center
BioSensics

Not yet recruiting

Digital Assessment of Speech and Fine Motor Control in ALS

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
Shandong Cancer Hospital and Institute

Recruiting

Radiotherapy Delays Second-line Drug Therapy for Oligo Progressive Primary Liver Cancer

Hepatocellular Carcinoma | Radiotherapy

China
Vesper Biotechnologies ApS

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001 in Healthy Participants (SORT-IN-1)

Dementia, Frontotemporal

Netherlands
DanceStream Projects
Alzheimer's Association

Recruiting

Stories in the Moment: Dance Program for People Living With Dementia

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia

United States
Power Life Sciences Inc.

Not yet recruiting

Revealing Engagement Dynamics Among Semantic Dementia Patients

Semantic Dementia

United States
University of Chicago
National Institute on Aging (NIA); Western University, Canada

Not yet recruiting

Communication Bridge Pilot Study (CB3_1)

Primary Progressive Aphasia

United States
New York Stem Cell Foundation Research Institute

Recruiting

NYSCF Scientific Discovery Biobank

PTSD | Multiple Sclerosis | Cervical Cancer | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Macular Degeneration | Diabetes Mellitus, Type 1 | Parkinson Disease | Amyotrophic Lateral Sclerosis | Dementia | Ovarian Cancer | Alzheimer Disease | ALS | Vulvar Cancer | Post Traumatic Stress Disorder | Lewy Body Disease and other conditions

United States
University of Chicago
National Institute on Aging (NIA); Western University, Canada

Not yet recruiting

Communication Bridge 3 Study (CB3)

Primary Progressive Aphasia

United States
Queen Mary University of London

Not yet recruiting

The Use of the CUE1 in People With Parkinson's Disease and Related Disorders

Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Tremor | Parkinson's Disease and Parkinsonism | Vascular Parkinsonism
Haukeland University Hospital
Nordlandssykehuset HF; Helse Møre og Romsdal HF; Helse Fonna HF; Oslo universitetssykehus... and other collaborators

Not yet recruiting

The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism (NADAPT)

Multiple System Atrophy | Progressive Supranuclear Palsy | Corticobasal Syndrome

Norway
National Cancer Institute (NCI)

Recruiting

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Glioma | Ependymoma | Medulloblastoma

United States
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Hypertension

United States, Italy, Germany, Australia, Canada, United Kingdom, Puerto Rico, Bulgaria, Spain
Stanford University
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents

Healthy Volunteers | Meningococcal Infection

United States, Puerto Rico
Nova Scotia Health Authority

Recruiting

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Insomnia | Dementia | Frontotemporal Dementia

Canada
University of Missouri-Columbia

Recruiting

Propranolol in Primary Progressive Aphasia

Aphasia, Primary Progressive

United States
AviadoBio Ltd

Recruiting

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN) (ASPIRE-FTD)

Frontotemporal Dementia | FTD | FTD-GRN | Dementia, Frontotemporal

Netherlands, Spain, Poland, United States
Nantes University Hospital

Not yet recruiting

Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders

Bipolar Disorder | Behavioral Variant of Frontotemporal Disorder (bvFTD) | Phenocopy Frontotemporal Dementia (phFTD) | Frontal Variant of Alzheimer Disease
Hacettepe University

Recruiting

Progressive Relaxation Training Effect On Pain, Activity And Social Participation In Women With Tension-Type Headache And Migraine

Migraine Disorders | Tension-Type Headache | Pain, Chronic

Turkey
IRCCS San Raffaele
Azienda Socio Sanitaria Territoriale della Valle Olona

Recruiting

Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis

Multiple Sclerosis

Italy
Merck Sharp & Dohme LLC

Recruiting

MK-0616 (Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Arteriosclerosis | Hypercholesterolaemia

United States, Taiwan, Canada, Israel, New Zealand, Hong Kong, Argentina, Korea, Republic of, Turkey, Australia, Chile, Brazil, Japan, Colombia, China, United Kingdom, Mexico, Peru
NewAmsterdam Pharma

Recruiting

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies (TANDEM)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | High Cholesterol | ASCVD

United States
Chinese University of Hong Kong

Recruiting

Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE) (LANDSCAPE)

Parkinson Disease | Aging | Dementia Alzheimers | Depression in Old Age | Dementia Frontotemporal

Hong Kong
Massachusetts General Hospital
Johns Hopkins University; BioSensics LLC

Recruiting

A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

Corticobasal Degeneration | Frontotemporal Dementia | Frontotemporal Lobar Degeneration | Progressive Supranuclear Palsy | CBD | FTD | PSP

United States
University Rovira i Virgili
Ministerio de Ciencia e Innovación, Spain

Recruiting

Dementias and Microbiota Composition: Is Possible to Revert the Dementia Symptoms Reverting the Microbiota Composition? (DEM-BIOTA)

Mild Cognitive Impairment | Dementia With Lewy Bodies | Dementia Alzheimers | Parkinson Disease Dementia | Dementia Frontotemporal

Spain
Daniel Serrani Azcurra
Zarebski Graciela, Kabanchik Alicia, Marconi Araceli

Recruiting

Multifactorial Approach to Dementia, Multicentric Study

Depression | Dementia of Alzheimer Type | Dementia Frontotemporal | Narcissistic Personality Disorder | Personality Change

Argentina
University of Florida
Johns Hopkins University; Massachusetts General Hospital; Washington University... and other collaborators

Recruiting

Automated Imaging Differentiation of Parkinsonism (AIDP)

Parkinson Disease | Progressive Supranuclear Palsy | Multiple System Atrophy, Parkinson Variant

United States, Canada
Lawson Health Research Institute

Recruiting

Investigating Genetic Status in Patients Presenting to Clinic

Lewy Body Dementia (LBD) | Alzheimer Dementia (AD) | Dementia, Frontotemporal

Canada
Shionogi

Recruiting

Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection (SCORPIO-PEP)

SARS-CoV-2 Infection

Japan, United States
University Hospital, Antwerp
Hasselt University; University Hospital, Ghent; AZ Sint-Jan AV; National MS Center... and other collaborators

Recruiting

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary-progressive Multiple Sclerosis

Belgium
University of Illinois at Urbana-Champaign
LSVT Global; Apple Inc.; Amazon.com Services LLC; Google LLC.; Microsoft Corporation and other collaborators

Recruiting

Speech Accessibility Project (SAP)

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy | Dementia With Lewy Bodies

United States
Children's Hospital Medical Center, Cincinnati
Patient-Centered Outcomes Research Institute

Recruiting

Responding With Evidence and Access for Childhood Headaches

Migraine | Migraine Disorders | Headache | Headache Disorders | Chronic Migraine | Migraine Without Aura | Migraine With Aura | Headache, Migraine

United States
National Cancer Institute (NCI)

Recruiting

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recurrent Langerhans Cell Histiocytosis | Refractory Langerhans Cell Histiocytosis

United States, Canada
University Hospital, Caen
University Hospital, Rouen; Rennes University Hospital

Recruiting

Memory and Social Interactions (MEM&SO)

Alzheimer Disease | Semantic Dementia

France
Western University

Recruiting

Genetic Frontotemporal Dementia Initiative for Neurodevelopment (GENFI-NeuroDev)

Frontotemporal Dementia | Family Members

Canada
Mayo Clinic
National Institute on Aging (NIA); Minnesota HealthSolutions

Recruiting

A Study of Caregiver Connections Via Technology in Dementia

Dementia | Alzheimer Disease | Frontotemporal Dementia | Lewy Body Dementia | Parkinson Disease Dementia | Caregiver Stress

United States
University of Texas at Austin
Hospital Clinic of Barcelona; Fundació Institut de Recerca de l'Hospital de...

Recruiting

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Language Disorders | Communication Disorders | Primary Progressive Aphasia | Aphasia | Speech Disorders | Frontotemporal Lobar Degeneration | Dysarthria | Apraxia, Motor | Dementia, Frontotemporal | Bilingual Aphasia

Spain, United States
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Fondazione Regionale per la Ricerca Biomedica (FRRB); IRCCS Fondazione Istituto... and other collaborators

Recruiting

A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931 (MAINSTREAM)

Primary Progressive Aphasia

Italy
University Health Network, Toronto
Weston Brain Institute

Recruiting

Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia (FRONSTIM)

Frontotemporal Dementia | Deep Brain Stimulation

Canada
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
University of California, San Francisco
University of Colorado, Denver; National Institute on Aging (NIA); HealthPartners... and other collaborators

Recruiting

The Care Ecosystem Consortium Effectiveness Study

Dementia | Frontotemporal Dementia | Dementia, Vascular | Dementia With Lewy Bodies | Dementia Alzheimers

United States
LAPIX Therapeutics Inc.

Recruiting

An Observational Biomarker Study in Multiple Sclerosis (MS) Patients

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Nantes University Hospital

Recruiting

Autobiographical Specificity (ESAD)

Alzheimer Disease | Frontotemporal Dementia | Memory

France
Conor Fearon
Queen's University

Recruiting

Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders

Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism

Ireland
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Niemann-Pick Disease, Type C

United States

Search clinical trials for: Aphasia, Primary Progressive

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