Search clinical trials for: Aryl Hydrocarbon Receptor

Total 18136 results

Assistance Publique Hopitaux De Marseille
Aix Marseille Université; ALPHENYX

Not yet recruiting

Involvement of Pollutants in Atopic Dermatitis and Psoriasis (DIAhR)

Psoriasis | Atopic Dermatitis
McMaster University

Recruiting

Tryptophan for Impaired AhR Signaling in Celiac Disease (TIARSCeD)

Celiac Disease | Tryptophan Metabolism Alterations

Canada
Bayer

Active, not recruiting

A Study to Learn How Safe the Study Drug BAY 2416964 (AhR Inhibitor) in Combination With the Treatment Pembrolizumab is, How This Combination Affects the Body, the Maximum Amount That Can be Given, How it Moves Into, Through and Out of the Body and Its Action Against Advanced Solid Cancers in Adults

Advanced Solid Tumors

United States, Singapore, Italy, United Kingdom
Ikena Oncology
Bristol-Myers Squibb

Withdrawn

Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Head Cancer | Neck Cancer | Head Cancer Neck | Neck Carcinoma

United States
Ikena Oncology
Bristol-Myers Squibb

Completed

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Neoplasms | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Bladder Cancer | Advanced Solid Tumor | Advanced Cancer | Urothelial Carcinoma Bladder | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | Bladder Disease | Solid Carcinoma | Neoplasm Malignant | Neoplasm, Bladder | Locally Advanced... and other conditions

United States
Bayer

Completed

A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer

Advanced Solid Tumors

Spain, United States, United Kingdom, Germany, Canada
Universidade Nova de Lisboa
Hospital da Luz, Portugal; Centro Hospitalar Lisboa Ocidental; Centro Hospitalar... and other collaborators

Active, not recruiting

Kynurenine/Tryptophan Ratio in Hypertension Associated to Obstructive Sleep Apnea (KYNTOSA)

Hypertension Secondary

Portugal
McMaster University
Canadian Institutes of Health Research (CIHR); National Research Agency, France

Completed

The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation (Aryl-IMMUNE)

Diet Modification

Canada
Dermavant Sciences GmbH
IQVIA Biotech

Completed

Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003)

Plaque Psoriasis

United States, Canada
TC Erciyes University

Unknown

Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene Mutations in Acromegaly (AIP)

Acromegaly

Turkey
National Taiwan University Hospital

Completed

The Role of Aromatic Hydrocarbon Receptor in the Tumorigenesis of Neuroblastoma and Its Relationship With MYCN Expression

Neuroblastoma
Mackay Memorial Hospital

Recruiting

Efficacy of Solifenacin or Mirabegron With Local Estrogen Versus Combination Pharmacotherapy for Overactive Bladder

Urinary Bladder, Overactive | Effect of Drug

Taiwan
Adicet Therapeutics

Not yet recruiting

A Phase 1/2 Trial of ADI-270 in ccRCC

Clear Cell Renal Cell Carcinoma
Ziekenhuis Oost-Limburg

Recruiting

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study (DEXSLEEP)

Postoperative Fatigue | Postoperative Sleep Disturbances | Surgical Stress Response

Belgium
National Cancer Institute (NCI)

Not yet recruiting

[212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers

Somatostatin Receptor Positive | Head and Neck Tumors | Small Cell Lung Cancers | Gastrointestinal Neuroendocrine Tumors | Pheochromocytoma/Paragangliomas | Kidney Cancers

United States
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma

Non-Hodgkin Lymphoma | Large B-cell Lymphoma

China
Ain Shams University

Recruiting

The Role of Levosimendan as Inotropic Agent in Acute Aluminum Phosphide-induced Cardiotoxicity

Acute Cardiotoxicity

Egypt
Novo Nordisk A/S

Not yet recruiting

A Research Study to Understand How People With Type 2 Diabetes Take Ozempic® and if the Ozempic®App Helps Them Stay on This Treatment

Diabetes Mellitus, Type 2

Greece
VA Office of Research and Development
University of Illinois at Chicago

Not yet recruiting

DRonabinol Treatment of OSA (DROSA)

Obstructive Sleep Apnea

United States
Peking Union Medical College Hospital

Recruiting

TPO-RA Treatment on Immune Tolerance Induction of ITP Patients With Sustained Platelet Recovery After Treatment Termination

Immune Thrombocytopenia

China
Myeloid Therapeutics

Not yet recruiting

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

Hepatocellular Carcinoma

Australia
European Institute of Oncology

Recruiting

Characterization of Biophysical and Mechanical Parameters on Skin of Breast Cancer Patients

Breast Cancer | Estrogen Receptor Positive Tumor

Italy
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of HRS5580 in Prevention of Postoperative Nausea and Vomiting of Adults

Preventing of Postoperative Nausea and Vomiting in Adults

China
Atif Shafqat

Recruiting

Opioid-based Versus Opioid-free Anaesthesia for Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy | Surgical Procedure, Unspecified

Pakistan
Assaf-Harofeh Medical Center

Recruiting

Comparison of the Effect of K Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Induced Following Treatment With Remifentanil

Cholecystectomy

Israel
Vejle Hospital
University of Aarhus; University of Southern Denmark; Region of Southern Denmark and other collaborators

Not yet recruiting

Reducing Breathlessness With Dronabinol in COPD Patients (BONG)

Cannabis | COPD | Breathlessness
University of Pittsburgh
Fogarty International Center of the National Institute of Health; K S Hegde...

Not yet recruiting

Prucalopride for Cognitive Functioning in Schizophrenia

Schizophrenia

India
AstraZeneca
Fortrea

Not yet recruiting

Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma. (ARRIVAL)

Severe Asthma
Antonios Likourezos

Not yet recruiting

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache

Migraine

United States
Santa Chiara Hospital

Recruiting

Evaluation of Clinical Outcomes of Chemotherapy or Androgen-receptor Targeting Agent (Alone or Combined) or Radiotherapy on Primary Tumor in Addition to Androgen Deprivation Therapy in HOrmone-Sensitive Metastatic Prostate Cancer Patients (ECHOS)

Prostate Cancer | Metastatic Tumor | Hormone Sensitive Prostate Cancer

Italy
University of Chicago

Not yet recruiting

Effects of Drugs on Stress Memories (ETS)

Stress | THC

United States
AstraZeneca

Not yet recruiting

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma (BAIYUN)

Asthma

China
Shanghai Changzheng Hospital
The First Affiliated Hospital of Nanchang University; Shanghai Zhongshan Hospital and other collaborators

Not yet recruiting

The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis

Hypertension, Portal
Fudan University

Not yet recruiting

Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer

Advanced Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer

China
Poznan University of Medical Sciences

Not yet recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Knee Osteoarthritis | Knee Arthritis | Knee Pain Chronic | Knee Disease

Poland
Peking University First Hospital
Peking University International Hospital; Tianjin Medical University General...

Not yet recruiting

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

Delirium | Dexmedetomidine | Aged | Intensive Care Units | Esketamine | Ventilators, Mechanical

China
University of California, Davis
Knownwell

Recruiting

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

Obesity

United States
United States Army Research Institute of Environmental...

Not yet recruiting

The Effects of Semaglutide on Body Composition and Performance in Military Personnel

Obesity
University of Aarhus

Recruiting

Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)

Urinary Incontinence in Children

Denmark
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause

Breast Cancer
Aretaieion University Hospital

Recruiting

Opioid-based Versus Opioid-free Endotracheal Intubation

Anesthesia | Opioid Use | Fentanyl | Analgesic Non-narcotic | Anesthesia Intubation

Greece
Egymedicalpedia

Recruiting

Dexmedetomidine Versus Midazolam-Fentanyl for Analgesia and Sedation

Valvular Cardiac Surgeries

Egypt
Belfast Health and Social Care Trust

Recruiting

CMR Right Ventricular Contractile Reserve Following Lung Resection

Lung Cancer | Surgery | Anesthesia

United Kingdom
Guangzhou Medical University

Not yet recruiting

Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases

Brain Metastasis
Zhejiang University
Carbiogene Therapeutics Co. Ltd.

Not yet recruiting

Clinical Trial of Autologous GPC3 CAR-T Cells (CBG166) Therapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

The Ameliorative Effects of GLP-1RA on Diabetic Cardiac Autonomatic Neuropathy

Type 2 Diabetes | Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)

China
University of Melbourne
Monash University; University of Adelaide; University of Sydney; The University... and other collaborators

Not yet recruiting

PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] (PLATIPUS)

Preterm Birth
First Affiliated Hospital of Zhejiang University
The Second Hospital of Hebei Medical University; Shenzhen Second People's Hospital and other collaborators

Not yet recruiting

Dobutamine for Management of Surgical Patients With Septic Shock

General Anesthesia | Surgical Patients | Patients With Septic Shock
TC Biopharm

Not yet recruiting

ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AML (ACHIEVE2)

Acute Myeloid Leukemia | Myelodysplastic Syndromes
Guangzhou Medical University

Not yet recruiting

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

Leptomeningeal Metastases

Search clinical trials for: Aryl Hydrocarbon Receptor

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