Search clinical trials for: Bioavailability and metabolism

Total 472182 results

Celgene

Not yet recruiting

A Study to Evaluate the Drug Levels, Metabolism and Excretion, and Absolute Bioavailability of BMS-986365 in Healthy Male Participants

Healthy Volunteers

United States
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Bioavailability and Food Effects of HRS-7535 Tablets With Different Formulating Processes in Healthy Subjects

Type 2 Diabetes Mellitus

China
Pfizer

Not yet recruiting

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

Healthy Participants
Instituto de Ciencia y Tecnología de Alimentos...
Ministry of Science and Innovation

Recruiting

Interindividual Variation in Response to Green Coffee (GREENCOF)

Overweight and Obesity

Spain
Pfizer

Completed

A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults

Healthy Participants

Netherlands
Millennium Pharmaceuticals, Inc.

Completed

A Study to Assess Absolute Bioavailability (ABA) of Mobocertinib (TAK-788) and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of Carbon-14 ([14C])-Mobocertinib in Male Healthy Participants

Healthy Volunteers

United States
Lykos Therapeutics

Completed

Food Effects on Bioavailability of MDMA in Healthy Volunteers (MPKF)

Pharmacokinetics

United States
Sanofi

Completed

A Study to Evaluate Absolute Bioavailability, Absorption, Metabolism, and Excretion of Genz-112638 in Healthy Male Participants

Gaucher's Disease Type I
Eisai Limited

Completed

A Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of Carbon-14 (14C)E7386 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Edgewise Therapeutics, Inc.

Completed

Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers

Nervous System Diseases | Genetic Diseases, Inborn | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Healthy Volunteer

United States
University of Wisconsin, Madison

Completed

Bioavailability of Aronia Berry Polyphenols

Polyphenols | Metabolism | Gut Health

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study of Bioavailability, Pharmacodynamics and Safety of SHR-1209 Administered by Single Subcutaneous Injection at Different Sites in Healthy Volunteers

Hypercholesterolemia and Hyperlipidemia

China
The Affiliated Hospital of Qingdao University

Completed

Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Hyperlipidemias

China
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants

Healthy

United States
AstraZeneca
Quotient Sciences

Completed

A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects

Chronic Kidney Disease | Type 2 Diabetes Mellitus (T2DM) | Non-alcoholic Steatohepatitis

United Kingdom
Galenicum Health

Completed

Comparative Bioavailability Study of Metformin/Sitagliptin 850 mg/50 mg Tablets in Healthy Male and Female Volunteers

Diabetes Mellitus, Type 2 | Bioequivalence

Canada
The University of The West Indies
International Atomic Energy Agency

Completed

Quality of Protein From the Common Bean

Nutrition Deficiency Due to A Particular Kind of Food

Jamaica
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
Swiss Federal Institute of Technology
Zurich University of Applied Sciences

Completed

Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 1) (Sustironable1)

Iron-deficiency

Switzerland
Swiss Federal Institute of Technology
Zurich University of Applied Sciences

Enrolling by invitation

Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 2) (Sustironable2)

Iron-deficiency

Switzerland
Eli Lilly and Company

Completed

A Study of [¹⁴C]-LY3484356 in Healthy Female Participants

Healthy

United States
Sanofi

Completed

Study to Determine Absorption, Metabolism, and Excretion of [14C]-SAR439859, and to Assess Absolute Oral Bioavailability of Amcenestrant (SAR439859), in Healthy Post-menopausal Women

Breast Cancer | Healthy Volunteers

United Kingdom
Sanofi

Completed

Study To Determine Bioavailability of Sotagliflozin in Healthy Male and Female Subjects

Type 2 Diabetes Mellitus | Healthy Subjects

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants

Healthy Volunteers

United States
Debiopharm International SA

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion and Absolute Bioavailability of Xevinapant in Healthy Male Participants

Healthy Volunteers

United Kingdom
Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Luxembourg Institute of Health
Université Catholique de Louvain; Laboratoires Réunis; Luxembourg Institute of...

Completed

Influence of Proteins on the Bioavailability of Carotenoids (CAROPROT)

Absorption; Chemicals | Healthy Diet | Metabolism

Luxembourg
Swiss Federal Institute of Technology
Mahidol University

Completed

Iron Bioavailability of High Surface Area Ferric Phosphate (HiFe)

Iron-deficiency

Thailand
Neurocrine Biosciences
Takeda

Completed

A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants

Healthy Volunteers

United States
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of [14C]Acp-196 (Acalabrutinib) in Healthy Adult Participants

Healthy Volunteers

United States
Swiss Federal Institute of Technology

Completed

Evaluation of Iron Bioavailability From Iron Chlorophyllin

Iron Deficiency

Switzerland
Zealand Pharma

Completed

Evaluation of the Safety, Tolerability and Bioavailability of Dasiglucagon Following Subcutaneous (SC) Compared to IV Administration

Hypoglycemia

Germany
SecuraBio

Completed

IPI-145 ADME and Absolute Bioavailability Study

Healthy

Netherlands
PepsiCo Global R&D

Completed

Bioavailability and Metabolism of Avenanthramide: a Novel Oat Phytochemical

Bioavailability | Metabolism | Avenanthramides
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioavailability Study for New Atorvastatin Formulation

Hypercholesterolemia

United States
Theravance Biopharma

Completed

TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects

Bowel Diseases, Inflammatory | Intestinal Disorders

United States
Pfizer

Completed

Study To Characterize Mass Balance, Absolute Bioavailability, Fraction Absorbed And Pharmacokinetics Of 14C PF-06882961

Healthy Volunteer

Netherlands
Green Beat
Medical University of Graz

Completed

Juice Plus+OMEGA Study

Healthy

Austria
North Carolina Agriculture & Technical State University

Completed

Avenanthramide and Saponin Bioavailability in Oat Bran

Pharmacokinetics | Polyphenols | Human Health
Clinical Nutrition Research Center, Illinois Institute...

Completed

Red Raspberry Polyphenols on Gut Microbiome (RRB2)

Healthy Subjects | Pre-diabetes

United States
Swiss Federal Institute of Technology
United States Agency for International Development (USAID); Quadram Institute... and other collaborators

Completed

IP Peru, Bioavailability of Iron From Potatoes (IPPERU)

Iron-deficiency | Iron Deficiency Anemia | Iron Deficiency (Without Anemia)

Peru
Children's Hospital of Philadelphia

Withdrawn

Gastrointestinal Implications of Voriconazole Exposure (GIVE)

Infection

United States
Parc de Salut Mar

Completed

Evaluation of Bioavailability and Metabolism of Diet Phenolic Compounds (dopet4)

Healthy

Spain
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

BAR-trial: Bioavailability of Ethanol Following Bariatric Surgery

Obesity, Morbid

Norway
Seoul National University Hospital

Unknown

To Investigate the Absorption, Metabolism, Excretion, Absolute Bioavailability, and Immunogenicity of GX-I7 in Healthy Volunteers

Leukopenia

Korea, Republic of
Tesaro, Inc.

Completed

Absorption, Metabolism, Excretion, and the Determination of Absolute Bioavailability of Niraparib in Subjects With Cancer

Cancer

Netherlands
Swiss Federal Institute of Technology
St. John's Research Institute

Completed

Effect of Polyphenols on Iron Absorption From Finger Millet

Iron-deficiency

Switzerland
Swiss Federal Institute of Technology
University of Malawi

Completed

Iron Bioavailability From Biofortified Orange-fleshed Sweet Potato (SASHA-II)

Iron-deficiency | Iron Deficiency Anemia

Malawi, Switzerland

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