Search clinical trials for: Biological Effects of rhIL-15

Total 431448 results

National Cancer Institute (NCI)

Completed

Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Renal Cell Carcinoma | Recurrent Skin Carcinoma | Stage III Renal Cell Cancer | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Non-Small Cell Lung Carcinoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IV... and other conditions

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Intravenous Recombinant Human IL-15 in Adults With Refractory Metastatic Malignant Melanoma and Metastatic Renal Cell Cancer

Melanoma | Carcinoma, Renal Cell

United States
National Cancer Institute (NCI)

Completed

Continuous Infusion of rhIL-15 for Adults With Advanced Cancer

Lymphoma | Carcinoma

United States
National Cancer Institute (NCI)

Completed

Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome

Mycosis Fungoides | Sezary Syndrome | Adult T-Cell Lymphoma/Leukemia

United States
Masonic Cancer Center, University of Minnesota

Completed

Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML)

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
National Cancer Institute (NCI)

Terminated

Human IL-15 (rhIL-15) and Obinutuzumab for Relapsed and Refractory Chronic Lymphocyte Leukemia

Leukemia | Chronic | Lymphocytic | B-Cell

United States
National Cancer Institute (NCI)

Completed

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

Sarcoma | Neuroblastoma | Solid Tumors | Brain Tumors | Pediatric Cancers

United States
National Cancer Institute (NCI)

Terminated

Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma

Clear-Cell Renal Carcinoma

United States
National Cancer Institute (NCI)

Completed

Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies

Mycosis Fungoides | Sezary Syndrome | Anaplastic Large Cell Lymphoma | Peripheral T-cell Lymphoma NOS

United States
National Cancer Institute (NCI)

Recruiting

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers

Metastatic Solid Tumors | Treatment-Refractory Cancers

United States
National Cancer Institute (NCI)

Completed

Subcutaneous Recombinant Human IL-15 (s.c. rhIL-15) and Alemtuzumab for People With Refractory or Relapsed Chronic and Acute Adult T-cell Leukemia (ATL)

Peripheral T-Cell Lymphoma (PTCL) | T-Cell Prolymphocytic Leukemia | Cutaneous T Cell Lymphoma (CTCL) | T-Cell Lymphoma Relapsed | Adult T-Cell Leukemia (ATL)

United States
Cytheris SA

Completed

Safety Study of IL-7 in HIV-infected Patients (Inspire)

HIV Infections | Lymphopenia

United States, France, Canada, Italy
NeoImmuneTech
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Terminated

A Trial of NT-I7 in COVID-19 (SPESELPIS)

COVID-19

United States
University of Chicago

Completed

Study of MAGE-3/Melan-A/gp 100/NA17 and rhIL-12 With/Out Low Dose IL-2 in Metastatic Melanoma

Metastatic Melanoma

United States
University of Pennsylvania

Completed

Long-term Follow-up of Subjects Exposed to Lentiviral-based CART-EGFRvIII Gene-modified Cellular Therapy Products in Cancer Studies

Subjects Entering Into This Protocol Will be Followed for up to 15 Years After Initial CART-EGFRvIII Infusion

United States
Cytheris, Inc.

Completed

Safety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell Transplant

AML | MDS | CML

United States
Mayo Clinic

Completed

Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor

Tremor

United States
The First Affiliated Hospital with Nanjing Medical...

Unknown

Study of Adjunctive Recombinant Human Interleukin-2 Therapy in Patients With MDR-TB (rhIL-2)

MDR TB

China
PT Kalbe Genexine Biologics
Genexine, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of GX-I7 in Elderly Patients With Asymptomatic or Mild Symptoms of COVID-19

Covid19

Indonesia
Genexine, Inc.

Terminated

Safety and Preliminary Efficacy Study of GX-I7 in Patients With COVID-19

Covid19

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary

Recurrent Brain Metastases | Progressive Brain Metastases

United States
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
Johns Hopkins Bloomberg School of Public Health
Bill and Melinda Gates Foundation; Hopkins Population Center's Mellon Grant; The...

Completed

A Comparison of Survey Methodologies to Elicit Sensitive Information From Adolescents in Urban India

Unmarried Male and Female Adolescents in the Age Group 15-19 Years in Pre-Identified Slums in Delhi, India
Hyunseok Kang, MD
NeoImmuneTech

Recruiting

NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing Surgery

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Resectable Oropharyngeal Squamous Cell Carcinoma

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating rhIL-11 in Left-Sided Ulcerative Colitis

Ulcerative Colitis | Inflammatory Bowel Disease
University Hospital, Strasbourg, France

Completed

Validation of a Pediatric Pictorial Version of the QOR-15 Postoperatory Functional Recovery Scale - QoR-15 Pédiatric

Surgical Intervention | Minor

France
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating rhIL-11 in Active Crohn's Disease

Crohn Disease | Inflammatory Bowel Disease

United States
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi

Completed

Turkish Version of the Postoperative QoR-15 (QoR-15T)

Surgery | Recovery of Function | Postoperative Period | Cross-Cultural Comparison

Turkey
Memorial Sloan Kettering Cancer Center
Celgene Corporation

Completed

Sequential Chemotherapy and Lenalidomide Followed by Rituximab and Lenalidomide Maintenance for Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma | Untreated

United States
Helwan University

Recruiting

The Effect of NAC in Decreasing the Incidence of Linezolid-induced Thrombocytopenia in Critically Ill Patients

Linezolid Induced Thrombocytopenia

Egypt
Northumbria University
Nektium Pharma SL

Completed

Acute Dose-ranging Effects of Mango Leaf Extract (Zynamite® 15%) on Cognitive Function and Cerebral Blood Flow

Cognitive Change

United Kingdom
Memorial Sloan Kettering Cancer Center
Center for Marital and Sexual Health of South Florida

Recruiting

Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery

Erectile Dysfunction | Prostate Cancer

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Low-dose rhIL-2 in Patients With Recently-diagnosed Type 1 Diabetes (DIABIL-2)

Type 1 Diabetes

Belgium, France, Germany, Netherlands, Sweden, Switzerland
Celularity Incorporated

Completed

A Safety Study of Human Cord Blood Derived, Culture-expanded, Natural Killer Cell (PNK-007) Infusion With or Without Subcutaneous Recombinant Human Interleukin-2 (rhIL-2) Following Autologous Stem Cell Transplant for Multiple Myeloma (MM)

Multiple Myeloma

United States
University of Oxford
University of Basel; ClinSearch; Fundação de Medicina Tropical Dr. Heitor Vieira... and other collaborators

Not yet recruiting

Evaluating Pediatric Ivermectin in Children Under 15 kg (EPIC-15) (EPIC-15)

Scabies

Brazil
Memorial Sloan Kettering Cancer Center

Active, not recruiting

BGJ398 in Non-Muscle-Invasive Urothelial Carcinoma of the Bladder

Bladder Cancer | Non-Muscle-Invasive Urothelial Carcinoma

United States
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Celiac Disease

Celiac Disease

Finland
Seoul National University Hospital

Withdrawn

Effects of Preoperative Anxiety and Depression on Short-term Postoperative Recovery in Early Gastric Cancer

Depression | Postoperative Complications | Anxiety | Coping Behavior

Korea, Republic of
Nobelpharma

Completed

Investigation of Arrhythmogenic Effect of NPC-15 (NPC-15-7)

Qt Interval, Variation in

Japan
Boehringer Ingelheim

Completed

Bioequivalence Study of Meloxicam Capsules 15 mg (Mobic® Capsules 15 mg) Versus Meloxicam Tablets 15 mg (Mobic® Tablets 15 mg) in Healthy Adult Volunteers

Healthy
University Hospital, Ghent

Completed

Comparison of Acute Toxicity and Cost Between Whole Breast Irradiation With Sequential Boost and Simultaneous Integrated Boost After Breast Conserving Surgery. (SeqB vs SIB)

Radiotherapy After Breast Conserving Surgery

Belgium
Celularity Incorporated

Terminated

A Safety Study of Human Cord Blood Derived, Culture Expanded Natural Killer Cell (PNK-007) Infusion With Subcutaneous Recombinant Human IL-2 (rhIL-2) in Adults With Relapsed and/or Refractory Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

United States
Dr. Reddy's Laboratories Limited

Completed

Bioavailability of DFN-15 at 3 Different Doses vs. Comparator and to Determine Dose-proportionality of DFN-15 in Fasting Healthy Adults

Healthy

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University

Completed

Body Composition and White Adipose Tissue Inflammation

Breast Cancer | Body Composition | Prostate Cancer | White Adipose Tissue Inflammation

United States
Tillotts Pharma AG

Completed

TP05 for the Treatment of Mild to Moderate Active Ulcerative Colitis (UC) (Precision-UC)

Acute Ulcerative Colitis

Switzerland
Dr. Reddy's Laboratories Limited

Completed

Two Dose Levels of DFN-15 vs. Placebo in Patients With Migraine Headaches

Migraine

United States
Hospital Universitario La Fe

Recruiting

The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section. (TRON)

Cesarean Section | Post Operative Pain | Quality of Recovery | Postoperative Recovery | Ondansetron | Tramadol | QoR-15 | ObsQor-10 | Postcesarean Recovery

Spain
Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd

Recruiting

Consistency, Immunogenicity, and Safety of Three Batches of 15-valent Pneumococcal Conjugate Vaccine

Healthy Volunteers

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Cancer Immunotherapy Trials Network (CITN)

Terminated

NT-I7 for Kaposi Sarcoma in Patients With or Without HIV

HIV Infection | Kaposi Sarcoma | AIDS-Related Kaposi Sarcoma

United States
Memorial Sloan Kettering Cancer Center
University of Pittsburgh; National Institutes of Health (NIH); Weill Medical...

Recruiting

Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer

Pancreatic Cancer | Benign Pancreatic Disease

United States

Search clinical trials for: Biological Effects of rhIL-15

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