Search clinical trials for: Busulfan pharmacokinetics

Total 10883 results

Intra-Cellular Therapies, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ITI 333 in Healthy Volunteers

Healthy Volunteers

United States
Peking University

Not yet recruiting

Phase Ib Clinical Study on the Safety, the Tolerability, the Pharmacokinetics and the Efficacy of ScTIL Injection (Gene Modified Tumor Infiltrating Lymphocytes) Alone and in Combination With B Lymphocyte Adjuvant in the Treatment of Digestive System Malignant Solid Tumors

Digestive System Malignant Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Bioequivalence Study of INS062 and Pharmacokinetics and Pharmacokinetics Study of Single Injection of HR20014 in Healthy Subjects

Diabetes

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Escalating Doses of SIM0348 as a Single Agent in Advanced Solid Tumors

Advanced Solid Tumors
Dongyang Liu

Recruiting

Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects

Health, Subjective | Nonvalvular Atrial Fibrillation

China
Merck Sharp & Dohme LLC

Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart Failure | Left Ventricular Systolic Dysfunction

Korea, Republic of, United States, France, Finland, Portugal, Sweden, Denmark, Spain, Turkey, Hungary, Netherlands, Ireland, Malaysia, Colombia, Germany, Singapore, Thailand, Italy, New Zealand, Belgium, Brazil, Canada, United Kingdom, South Africa
Saladax Biomedical, Inc.

Not yet recruiting

Busulfan Sample Collection Study

Subjects Treated With Busulfan
Arcturus Therapeutics, Inc.
Novotech CRO

Recruiting

Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibrosis.

Cystic Fibrosis

New Zealand
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers

Healthy

Korea, Republic of
L & L biopharma Co., Ltd., Shanghai China

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001） (MEETCD8-001)

Solid Tumor

China
Addpharma Inc.

Recruiting

A Study to Assess the Safety and Pharmacokinetics of AD-104-A

Hyperlipidemias

Korea, Republic of
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II (APPEASEDII)

Diabetes Mellitus, Type 2 | Type 2 Diabetes | Platelet Aggregation | Aspirin | Platelet Aggregation Inhibitors

Canada
Keymed Biosciences Co.Ltd

Recruiting

Study to Evaluate Pharmacokinetics, Safety and Efficacy of CM310

Healthy

China
Haukeland University Hospital

Recruiting

NAD-brain: a Pharmacokinetic Study of NAD Replenishment Therapy (NAD-brain)

Healthy

Norway
Incyte Corporation

Recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis

Kidney Diseases | Renal Insufficiency

United States, Germany
Zhongnan Hospital

Not yet recruiting

Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma

MGMT-Unmethylated Glioblastoma
Assistance Publique - Hôpitaux de Paris

Recruiting

Oral Glibenclamide in Preterm Infants With Hyperglycaemia (GALOP) (GALOP)

Preterm | Transient; Hypoglycemia, Neonatal | Glibenclamide Adverse Reaction

France
University of Mississippi Medical Center
Eli Lilly and Company

Recruiting

Empagliflozin in ESKD - A Feasibility Study

Heart Failure | Kidney Failure, Chronic

United States
University Health Network, Toronto
The Physicians' Services Incorporated Foundation

Not yet recruiting

Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation (Vol-ECMO)

Respiratory Failure
University of Liverpool
Infectious Diseases Institute, Makerere University College of Health Sciences and other collaborators

Recruiting

Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant Pairs (MILK Malaria)

Malaria,Falciparum

Uganda
ViiV Healthcare
Janssen Research & Development, LLC

Recruiting

Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics

HIV Infections

United States
Wuhan Union Hospital, China

Recruiting

Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Allogeneic Hematopoietic Stem Cell Transplantation | Acute Myeloid Leukemia, Adult | Myelodysplastic Syndrome(MDS)

China
argenx

Recruiting

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Healthy Volunteers

Netherlands
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Population Pharmacokinetics/Pharmacodynamics of Carbapenems in Febrile Neutropenia Patients

Febrile Neutropenia | Pharmacokinetics | Pharmacodynamic | Carbapenems
Aadi Bioscience, Inc.

Recruiting

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Advanced Solid Tumor | Tumor | Tumor, Solid

United States
AstraZeneca

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy Subjects and to Assess the Relative Oral Bioavailability Between Two Formulations. The Study Will Also Assess the Food Effect on the PK of AZD6793 Compared to Fasting State

Inflammatory Diseases

United Kingdom
Alnylam Pharmaceuticals

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects

Transthyretin-Mediated Amyloidosis

United Kingdom
Children's Hospital Medical Center, Cincinnati
Jinja Regional Referral Hospital (JRRH), Sickle Cell Clinic, Jinja, Uganda

Recruiting

Alternative Dosing And Prevention of Transfusions (ADAPT)

Sickle Cell Disease

Uganda
BeiGene

Recruiting

A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors.

Melanoma | Renal Cell Carcinoma | Urothelial Carcinoma

China
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors (SKYSCRAPER-11)

PD-L1-selected Solid Tumors

Korea, Republic of, United States, Spain, Taiwan, Turkey, Greece, Canada, Croatia, Serbia, Mexico, Cyprus, Georgia
GlaxoSmithKline

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years

Hematologic Diseases | Anaemia, Sickle Cell

United States
Guangzhou Magpie Pharmaceuticals Co., Ltd.

Not yet recruiting

A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of MN-08 Tablets

Pulmonary Arterial Hypertension
Genentech, Inc.

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

Chronic Refractory Cough (CRC) With Non-atopic Asthma | CRC With Atopic Asthma | Unexplained Chronic Cough | CRC With Chronic Obstructive Pulmonary Disease | CRC With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis

United States, Australia, United Kingdom, Canada
ADC Therapeutics S.A.

Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10)

Diffuse Large B-Cell Lymphoma | High-grade B-cell Lymphoma

Taiwan, Korea, Republic of, United States, Brazil
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) (SREC22)

Nicotine Dependence | Cardiovascular Risk Factors | Tobacco Toxicity

United States
Sage Therapeutics
Biogen

Recruiting

Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder

United States
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Safety,Tolerability,and Pharmacokinetics of Multiple-Ascending Dose JS1-1-01 in Healty Subjects.

Healthy Volunteers

China
Tasly Biopharmaceuticals Co., Ltd.

Recruiting

A Trial to Evaluate the Safety Tolerability and Pharmacokinetics of B1344 by Subcutaneous Injection in Healthy Subjects

Nonalcoholic Steatohepatitis

United States
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single Ascending Doses Phase I Study to Evaluate the Safety and Pharmacokinetics of RBD4059 in Healthy Subjects

Healthy Volunteers

Australia
Geropharm

Recruiting

Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141

Pharmacokinetics | Pharmacodynamics | Bioequivalence

Russian Federation
Shandong Boan Biotechnology Co., Ltd

Recruiting

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1106 in Advanced Solid Tumors

Solid Tumors

China
Radboud University Medical Center
Merck Sharp & Dohme LLC; ZonMw: The Netherlands Organisation for Health Research...

Recruiting

Study on PhArmacokinetics of First liNe Antiretrovirals in Healthy Breastfeeding Volunteers (PANNA-B PK)

Hiv

Netherlands
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of XmAb24306 in Combination With Cevostamab in Participants With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

Australia, Spain, Israel, Korea, Republic of, Greece, Norway, Denmark
Grifols Therapeutics LLC

Recruiting

A Study to Evaluate Efficacy, Safety, and Pharmacokinetics of XEMBIFY® Plus Standard Medical Treatment (SMT) Compared to Placebo Plus SMT to Prevent Infections in Participants With Hypogammaglobulinemia and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia

Bacterial Infections | B-cell Chronic Lymphocytic Leukemia | Hypogammaglobulinemia

United States, Bulgaria, Poland, Romania, Serbia
Alexion Pharmaceuticals, Inc.

Recruiting

Evaluation of Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicity of Ravulizumab Administered Intravenously in Pediatric Participants With Generalized Myasthenia Gravis (gMG)

Generalized Myasthenia Gravis | gMG

Spain, Italy, United States, France, Switzerland, Serbia, Japan, Netherlands
Palvella Therapeutics, Inc.

Recruiting

A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

Pachyonychia Congenita

United States
H. Lee Moffitt Cancer Center and Research Institute
James and Esther King Biomedical Research Program

Recruiting

Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)

Smoking Cessation | Cervical Cancer | High Grade Cervical Dysplasia

United States
Zhejiang Doer Biologics Co., Ltd.

Recruiting

A Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of DR30303 in Patients With Advanced Solid Tumors

Malignant Neoplasm of Digestive System

China
Masonic Cancer Center, University of Minnesota

Recruiting

Evaluation of Intravenous Laronidase Pharmacokinetics Before and After Hematopoietic Cell Transplantation in Patients With Mucopolysaccharidosis Type IH.

Mucopolysaccharidosis Type I | Hematopoietic Cell Transplantation

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

A Clinical Study to Evaluate Safety, Tolerance, Pharmacokinetics and Efficacy of Sc610 Injection for Treating Advanced Urinary System Tumors

Malignant Tumor of Urinary System (Disorder)

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