Search clinical trials for: CML. Chronic myelocytic leukemia. Philadelphia Chromosome. Japanese. SKI-606. Bosutinib. Imatinib re

Total 404307 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI); Pfizer

Terminated

Bosutinib in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase After Frontline TKI Failure

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Blasts Under 15 Percent of Bone Marrow Nucleated Cells | Blasts Under 15 Percent of Peripheral Blood White Cells | Blasts Under 30 Percent of Bone Marrow Nucleated Cells | Blasts Under 30 Percent of Peripheral Blood White Cells

United States
Massachusetts General Hospital
Pfizer; Dana-Farber Cancer Institute; Brigham and Women's Hospital

Completed

Bosutinib in Adult Patients With Recurrent Glioblastoma

Glioblastoma

United States
Pfizer

Completed

Bioequivalence And Food Effect Study Of Bosutinib In Healthy Subjects

Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia (CML)

Singapore
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast Cancer

Breast Neoplasms | Neoplasm Metastasis

United States, Ukraine, Russian Federation, Hong Kong, France, Australia, Poland, Malta
University of Milano Bicocca
IRCCS San Raffaele

Completed

Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy

Leukemia | BCR-ABL Positive | Myelogenous | Chronic

Italy
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive Leukemias

Chronic Myelogenous Leukemia

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating SKI-606 in Subject With Solid Tumors

Tumors
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Mass Balance And Metabolic Disposition Of SKI-606

Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating SKI-606 Administered to Healthy Subjects

Healthy

Netherlands
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive Leukemias

Chronic Myeloid Leukemia

United States, Spain, Australia, Canada, Hong Kong, Singapore, United Kingdom, Germany, Netherlands, Chile, India, South Africa, Sweden, Peru, Argentina, Italy, Austria, Colombia, Brazil, China, Finland, Hungary, Korea, Republic of, M... and more
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Two Different Tablet Formulations Of Bosutinib Under Fed Conditions

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Two Different Tablet Formulations Of Bosutinib

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Drug Interaction Between Multiple Doses of Ketoconazole and a Single Dose of SKI-606

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating 3 New Formulations of SKI-606 in Healthy Adult Subjects

Healthy

United States
Georgetown University
Alzheimer's Association

Completed

Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies

Dementia With Lewy Bodies

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Axitinib and Bosutinib in Treating Patients With Chronic, Accelerated, or Blastic Phase Chronic Myeloid Leukemia

Accelerated Phase Chronic Myelogenous Leukemia (CML) | Blast Phase Chronic Myelogenous Leukemia (CML) | Chronic Phase Phase Chronic Myelogenous Leukemia (CML) | Philadelphia Chromosome Positive (Ph+) Phase Chronic Myelogenous Leukemia (CML)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML

Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | B Acute Lymphoblastic Leukemia With t(9;22)(q34... and other conditions

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Ascending Single-Dose Of Bosutinib Administered With Multiple Doses Of Ketoconazole To Healthy Subjects

Leukemia | Breast Cancer | Tumors

Netherlands
University of California, San Francisco
University of Utah

Terminated

A Study Evaluating Gemcitabine Plus Bosutinib for Patients With Resected Pancreatic Cancer

Pancreatic Cancer

United States
Pfizer
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML

Chronic Myeloid Leukemia

France, United States, Spain, Belgium, Singapore, Poland, Canada, Japan, United Kingdom, Taiwan, Hungary, Germany, Argentina, Russian Federation, Turkey, Colombia, Italy, South Africa, Brazil, Chile, China, Hong Kong, India, Korea, Republic... and more
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Advanced Malignant Solid Tumors

Neoplasms

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Effect of Bosutinib (SKI-606) On Cardiac Repolarization (Rhythms Of The Heart)

Healthy Subjects

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Peking University Third Hospital

Completed

Analysis of the Mass Skiers' Injury in a Large Ski Resort in Chongli, China

Skiing Injury

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Potential Effect Of Lansoprazole On The Pharmacokinetics Of Bosutinib In Healthy Subjects

Healthy

United States
Oscotec Inc.

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-SKI-O-703 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Pfizer

Terminated

A Study to Evaluate the Efficacy and Safety of CP-101,606 in Subjects With an Acute Stroke

Stroke

United States, Italy, Spain, Singapore, Germany, Estonia, Portugal, Hungary
USANA Health Sciences

Recruiting

A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or Severity of URTIs Among Skiers

Upper Respiratory Tract Infections | Mental Stress

United States
USANA Health Sciences
U.S. Ski & Snowboard

Completed

The Acute Effects of a Dietary Supplement on Cognitive Performance in Highly Trained Athletes.

Reaction Time

United States
Oscotec Inc.
PPD

Completed

Safety, Tolerability, and Pharmacokinetics of a Single Oral Dose of SKI-O-703 in Healthy Volunteers

Rheumatoid Arthritis

United States
Oscotec Inc.
PPD

Completed

Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of SKI-O-703 in Healthy Volunteers

Arthritis, Rheumatoid

United States
Oscotec Inc.

Completed

Study of Oral SKI-O-703, SYK Inhibitor, in Patients With Persistent and Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

United States, Greece, Korea, Republic of, Poland, Spain
Oscotec Inc.
PPD

Completed

Study to Find a Safe and Effective Dose of SKI-G-801 in the Treatment of Patients With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Paracelsus Medical University

Completed

Metabolic and Physiological Stress During Skiing.

Healthy

Austria
Oscotec Inc.

Unknown

A Study to Evaluate the Effectiveness and Safety of SKI-O-703 in Patients Experiencing Active Rheumatoid Arthritis Despite Treatment With Conventional Therapies.

Rheumatoid Arthritis

United States, Czechia, Poland, Russian Federation, Ukraine
China Medical University Hospital
Ministry of Science and Technology, Taiwan

Active, not recruiting

Strong Kidney Initiative Trial for Dialysis Care Quality (SKI)

Hemodialysis Complication

Taiwan
Oscotec Inc.

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SKI-G-801 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Korea, Republic of
Myant Medical Corp.
Jodha Tishon Inc

Recruiting

Skiin-PSG Sleep Apnea

Obstructive Sleep Apnea

Canada
University of Salzburg
University of Copenhagen; Manchester Metropolitan University; Paracelsus Medical... and other collaborators

Completed

Health Benefits of Alpine Skiing for the Elderly (SASES)

Elderly | Exercise Capacity | Strength | Postural Control

Austria
Indonesia University

Recruiting

Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group

Acute Kidney Injury Due to Sepsis

Indonesia
Myant Medical Corp.
University of Waterloo

Completed

Validation of Smart Garments for Metabolic Rate Estimation

Healthy

Canada
Sonavex, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Prospective Feasibility Study Evaluating EchoMark LP Placement and EchoSure Measurements for Subjects Requiring Arteriovenous Fistulae

Kidney Diseases | Arteriovenous Fistula

United States
Medical University Innsbruck
Institute of Mountain Emergency Medicine

Active, not recruiting

A 13-years Nationwide Study of Alpine Accidents in Austria

Climbing | Alpine Accident | Sleighing | Cycling | Canyoning | Hiking | Snowshoeing | Alpine Water-sport | Skiing/Snowboarding

Austria
Myant Medical Corp.
Partners in Advanced Cardiac Evaluation

Completed

Holter Versus Skiin Garments

Cardiac Arrhythmia

Canada
Ecole Nationale des Sports de Montagne
Center for Physical Activity Research, University Hospital of Copenhagen,... and other collaborators

Enrolling by invitation

Intravascular Volumes in Hypoxia During Antarctic Confinement (ANTARCV)

Hypoxia | Confinement

France
University Hospital, Grenoble

Completed

New Psychoactive Substances in Intoxicated Patients During the Winter Activities (SkiTox)

Psychoactive Substance Use | Acute Intoxication

France
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Tirapazamine Plus Cisplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States, Canada, United Kingdom, Australia
NEAT ID Foundation
PENTA Foundation; European Commission; VERDI Consortium

Recruiting

Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV (MASH 1)

Monkeypox | HIV Coinfection

Spain, France, Poland, United Kingdom
Memorial Sloan Kettering Cancer Center

Completed

PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-Derivative

Melanoma | Sarcoma | Lymphoma | Carcinoma | Myeloma

United States
Myant Medical Corp.
University of Waterloo

Recruiting

Validation of Smart Garments for Gait Classification

Healthy

Canada

Search clinical trials for: CML. Chronic myelocytic leukemia. Philadelphia Chromosome. Japanese. SKI-606. Bosutinib. Imatinib re

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