Metabolic and Physiological Stress During Skiing.

April 28, 2015 updated by: Prof. Josef Niebauer M.D., Ph.D., MBA, Paracelsus Medical University

Metabolic and Physiological Stress During Alpine Skiing, Cross-country Skiing and Indoor Training in Untrained and Trained Persons.

Problem description In industrialized countries there is a rapid increase in the number of senior citizens. In Austria more than 50% of the population is overweight, with highest prevalence in the age group from 60 to 74 yrs and the WHO lists physical inactivity as one of the main behavioral risk factors of cardiovascular diseases.

Especially in winter months, activity related energy expenditure was 40% and 31% lower in the US and Canada, respectively. In addition, in an Austrian study the winter season was associated with higher blood pressure, total cholesterol and body mass index, giving an increasing risk of chronic coronary disease by 6.8% in men and 3.6% in women.

Therefore, the development of intervention programs that overcome the winter physical activity deficit and be feasible also for elderly should be goal of future research. Alpine skiing (AS) and cross country skiing (XCS) have a long standing tradition in Austria and could potentially fill the winter physical activity gap. The Salzburg Skiing for the Elderly Study (SASES) has found AS to be a save and feasible possibility to improve the health of the aged population in many parameters. XCS as a competitive sport is already well explored but there are hardly any studies about its effects in the normal or elderly population. Unfortunately knowledge about the differences between AS and XCS in the physiological adaptation processes in the elderly population is also lacking.

Aims and hypotheses of the pre-study In order to standardize training interventions, the present pre-study aims at comparing physiological and metabolic parameters between AS, XCS and IT. Therefore, the results of the pre-study serve as determinants for the training parameters of the above mentioned main study.

We postulate that, based on the results of the present study, it is possible to set up comparable isocaloric training sessions for AS, XCS and IT for elderly and unfit persons.

Furthermore, we assume that elderly and unfit subjects are able to perform a full spectrum of intensities and techniques necessary to set appropriate stimuli for isocaloric comparison.

We hypothesize arterial stiffness indices and circulating microRNA (miRNA) patterns to change due to one bout of physical activity of AS, XCS, and IT with variations depending on the kind of sport.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

21

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Austria
      • Salzburg, Austria, A-5020
        • University Institute of Sports Medicine, Prevention and Rehabilitation

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

30 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Twenty healthy subjects (male=10/female=10) aged 30+ will be recruited.

Description

Inclusion Criteria:

  • written informed consent
  • male or female
  • age: 30+ years
  • inconspicuous ECG
  • Non-smoker for at least one year
  • proper skills in alpine skiing and cross-country skiing

Exclusion Criteria:

  • Participation in other clinical trials at the same time or within the previous 6 months
  • Tiffeneau-Pinelli index: Forced Expiratory Volume in first second (FEV1) / Forced Vital Capacity (FVC) <60% with/without symptoms (coughing, sputum) or other evidence of a pulmonary disease
  • medical condition which conflicts with participation in training
  • Intake of anticoagulants
  • Alcohol or drug abuse
  • Severe obesity: BMI >40

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Cross-Sectional

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
males/females
Participants should be capable of alpine skiing and cross country skiing.
Other: Alpine skiing
Other: cross country skiing
Other: Indoor training (cycling)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Oxygen consumption (VO2)
Time Frame: 12 weeks
VO2 will be measured during during physical examination, indoor training, Alpine Skiing, and Cross Country Skiing. VO2 will be transformed into metabolic equivalents to calculate isocaloric training parameters for the different kind of sport.
12 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pulse wave analysis (PWA)
Time Frame: 12 weeks
PWA will be measured before/after physical examination, indoor training, Alpine Skiing, and Cross Country Skiing. PWA will be done by oscillometric measurement to calculate influence of acute exercise and training status on several pulse wave parameters.
12 weeks

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
RNA
Time Frame: 12 weeks
Total RNA will be isolated from stored plasma and blood cell samples. All samples will be screened for influence of acute exercise (before/after physical examination and indoor training).
12 weeks
Nitric oxide (NO)
Time Frame: 12 weeks
NO will be quantified out of stored blood samples and serves as a possible surrogate parameter of pulse wave analysis.
12 weeks
Metabolic screening
Time Frame: 12 weeks
Metabolic parameters (e.g. glucose, lactate) will be quantified out of stored blood samples: These parameters serve as determinants of the different exercises.
12 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Paracelsus Medical University

Investigators

  • Principal Investigator: Josef Niebauer, MBA, Prof. Dr.Dr., Paracelsus Medical University
  • Study Chair: Martin Schoenfelder, Dr., Research Institute of Moleclar Sport and Rehabilitation Medicine, Paracelsus Medical University Salzburg, Austria
  • Study Chair: Thomas Stoeggl, Prof. Dr., Department of Sport Sciency and Kinesiology - University of Salzburg

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2014

Primary Completion (Actual)

May 1, 2014

Study Completion (Actual)

May 1, 2014

Study Registration Dates

First Submitted

February 11, 2014

First Submitted That Met QC Criteria

March 5, 2014

First Posted (Estimate)

March 10, 2014

Study Record Updates

Last Update Posted (Estimate)

April 29, 2015

Last Update Submitted That Met QC Criteria

April 28, 2015

Last Verified

April 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • UISM-2014-MET-SKI

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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