Search clinical trials for: Cardiac safety

Total 74886 results

ResoTher Pharma

Recruiting

An Exploratory, Randomised, Double-blind Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI)

ST Elevation Myocardial Infarction

Denmark
Emory University
The Marcus Foundation

Not yet recruiting

A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)

Dilated Cardiomyopathy

United States
Emory University
University of California, San Diego; Ventrix, Inc.

Not yet recruiting

Study of Intramyocardial Injection of Ventrix Bio Extracellular Matrix (VentriGel) to Assess the Safety and Feasibility in Pediatric Patients With Hypoplastic Left Heart Syndrome (HLHS)

Hypoplastic Left Heart Syndrome

United States
MicroPort CRM

Not yet recruiting

Safety and Performance Evaluation of a New Catheter Range for Lead Implantation at Interventricular Septum (POLARIS)

Bradycardia | Cardiac Resynchronization Therapy | Left Bundle Branch Area Pacing
Regional Cardiology Center, The Copper Health Centre...
Department of Cardiology, Provincial Specialized Hospital in Legnica, 59-200...

Recruiting

Lower Silesian Orbital Atherectomy Registry (LOAR) (LOAR)

Safety Issues | Efficacy, Self

Poland
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
Xuanwu Hospital, Beijing

Not yet recruiting

Long-term Procedural and Device Related Complications of PFO Closure

Patent Foramen Ovale
East and North Hertfordshire NHS Trust
Professor Eliano Navarese (Co-Principal Investigator)

Not yet recruiting

Safety of AI-Powered Virtual Assistant in Outpatient Management of Heart Failure

Heart Failure
Shanghai Zhongshan Hospital

Not yet recruiting

The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis

Glucocorticoid Resistant ICIs-related Myocarditis
China National Center for Cardiovascular Diseases

Recruiting

Efficacy and Safety of Thoracoscopic Morrow Surgery in the Treatment of Hypertrophic Obstructive Cardiomyopathy

Minimally Invasive Surgery | Cardiomyopathy, Hypertrophic Obstructive

China
AstraZeneca
Parexel

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral AZD0233 Compared With Placebo in Healthy Adult Participants.

Dilated Cardiomyopathy

United States
Pediatric Clinical Research Platform
University Hospital, Geneva

Not yet recruiting

Performance and Safety of the Pneumoscope Device in Adults and Children

Pneumonia | Asthma | Respiratory Diseases | Cyanotic Heart Disease

Switzerland
The People's Hospital of Gaozhou

Recruiting

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

China
Medical University of Vienna
Ludwig Boltzmann Institute Digital Health and Patient Safety

Recruiting

Tele-Support for Emergency Medical Technicians (POHCA)

Cardiac Arrest

Austria
Starmed
Helptrial

Not yet recruiting

To Compare and Evaluate the Efficacy and Safety Between TS-RF System and BRK Transseptal Needles Used for Transseptal Puncture for Left Atrial Access.

Heart Diseases | Atrial Fibrillation | Arrhythmias, Cardiac
Tang Ziren

Not yet recruiting

Butylphthalide's Safety and Efficacy for Improving Neurological Function Prognosis in Patients With Cardiac Arrest (BNCA Trial)

Cardiac Arrest | Butylphthalide | Neuroprotective Drugs

China
Angiowave Imaging

Not yet recruiting

Clinical Evaluation of Radiation Reduction for Optimized Safety (CERROS)

Myocardial Infarction | Coronary Artery Disease | Coronary Disease | Chest Pain | Angina Pectoris | Coronary Stenosis

United States
BrosMed Medical Co., Ltd
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels

Coronary Artery Disease
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Not yet recruiting

A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF (DISRUPT-AF)

Atrial Fibrillation

United States
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation. (QDOT PAS)

Paroxysmal Atrial Fibrillation

United States
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Johns Hopkins University
Magic That Matters

Not yet recruiting

Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial

Myocardial Stunning

United States
JW Medical Systems Ltd

Not yet recruiting

Effectiveness and Safety of Coronary Scoring Balloon Dilation Catheter in the Pretreatment of Coronary Stenosis Lesions

Coronary Artery Disease
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Australia, Spain, Canada, Argentina, China, Italy, France, Japan, Taiwan, Korea, Republic of, Denmark, Germany, Hungary, Israel, Austria, Belgium, Netherlands, Brazil, Mexico, Romania, United Kingdom, Greece, Czechia, Poland and more
Regional Cardiology Center, The Copper Health Centre...

Recruiting

Lower Silesia Sinus Reducer Registry (LSSRR)

Safety Issues | Efficacy, Self

Poland
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

Study on the Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-2004 Injection in Adult Patients With Atrial Fibrillation

Atrial Fibrillation
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Respiratory Distress Syndrome After Cardiac Surgery :a Single Centre Random Control Trial.

Cardiac Disease
Pacira Pharmaceuticals, Inc

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

Postoperative Pain

United States
River 2 Renal Corp.
International HealthCare, LLC

Not yet recruiting

To Evaluate the Safety, Tolerability and Efficacy of R2R01 Combined With SOC as Compared to SOC Alone in Outpatients With Worsening Heart Failure (WHF)

Heart Failure | Worsening Heart Failure (WHF)

United States
Xijing Hospital

Recruiting

Safety and Efficacy of Post-marketing Transcatheter Aortic Valves in "Real World" Chinese Patients

Aortic Valve Disease Mixed

China
Medical University of Vienna
Ludwig Boltzmann Institute Digital Health and Patient Safety; Emergency Medical...

Recruiting

Feasibility of Doppler Ultrasound for Pulse Detection in Out-of-Hospital Cardiac Arrest Patients

Cardiac Arrest, Out-Of-Hospital

Austria
Tenaya Therapeutics
Johns Hopkins University; Mayo Clinic

Recruiting

Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC (RIDGE-1)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States
Cardurion Pharmaceuticals, Inc.

Recruiting

A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF) (Cycle-1-REF)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Heart Failure With Reduced Ejection Fraction

United States
Cardurion Pharmaceuticals, Inc.

Recruiting

Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF) (Cycle-2-PEF)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Heart Failure Preserved Ejection Fraction

United States
Yi Han
Qianfoshan Hospital

Recruiting

Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Heart Failure | Efficacy | Safety | Levosimendan | Milrinone

China
Boehringer Ingelheim

Recruiting

A Study to Test Whether Multiple Doses of BI 456906 Have an Effect on Cardiac Safety in People With Overweight or Obesity

Obesity | Overweight

Germany
Chelyabinsk Regional Clinical Hospital

Recruiting

Early Safety and Clinical Efficacy of Mitral Allograft in Tricuspid Surgery (ESEMATS)

Tricuspid Valve Insufficiency | Allografts

Russian Federation
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
Mirum Pharmaceuticals, Inc.

Recruiting

Long-Term Safety and Clinical Outcomes of Livmarli in Patients With Alagille Syndrome (LEAP) (LEAP)

Alagille Syndrome

United States
Korea University Anam Hospital

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Rivaroxaban 15mg and 20mg in Patients With Non-valvular Atrial Fibrillation (REVISE-AF)

Atrial Fibrillation | Anticoagulant Adverse Reaction

Korea, Republic of
Genoss Co., Ltd.

Recruiting

Safety and Effectiveness of GENOSS DES in Patients With Multivessel Coronary Artery Disease (GENOSS-MV)

Percutaneous Coronary Intervention | Multivessel Coronary Artery Disease

Korea, Republic of
Second Xiangya Hospital of Central South University

Recruiting

Safety and Efficacy of Stereotactic Body Radiotherapy in the Treatment of Hypertrophic Obstructive Cardiomyopathy (SAFECARE)

Hypertrophic Obstructive Cardiomyopathy | Stereotactic Body Radiotherapy

China
Edwards Lifesciences

Not yet recruiting

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Mitral Regurgitation | Mitral Valve Disease | Mitral Stenosis
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
Ever Supreme Bio Technology Co., Ltd.

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells as an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients

ST Elevation Myocardial Infarction

Taiwan
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

Korea, Republic of

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