Search clinical trials for: Creatine transporter

Total 1739 results

Hospices Civils de Lyon

Recruiting

Relevant Outcome Measures for Creatine Transporter Deficiency Patient (CREAT_criteria)

Creatine Transporter Defect

France
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls

Niemann-Pick Disease Type C1 | Juvenile Neuronal Ceroid Lipofuscinosis | Smith-Lemli-Opitz Syndrome | Creatine Transporter Deficiency

United States
Eunice Kennedy Shriver National Institute of Child...
McMaster University, Ontario, Canada

Recruiting

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

Autism Spectrum Disorder | Metabolic Disease | Cognitive Disorder

United States
Inspirna, Inc.

Recruiting

A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer

Gastrointestinal Neoplasms | Colorectal Neoplasms | Gastric Cancer | Colorectal Cancer | Colorectal Cancer Metastatic | Gastrointestinal Cancer | Colorectal Carcinoma | CRC | KRAS Mutation-Related Tumors | Gastric Neoplasm

United States
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Creatine Deficiency Syndromes (BioCDS) (BioCDS)

Intellectual Disability | Developmental Delay | Intractable Epilepsy | Movement Disorder | Behavioral Disorder

India, Sri Lanka, Egypt
Ultragenyx Pharmaceutical Inc

Terminated

Observational Study of Males With Creatine Transporter Deficiency (Vigilan)

Creatine Deficiency, X-linked

United States, Canada
Beijing Anzhen Hospital

Not yet recruiting

Efficacy of Dapagliflozin on Recurrence After Catheter Ablation for Atrial Fibrillation (DARE-AF)

Atrial Fibrillation

China
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy (SOTA-CROSS HCM)

Hypertrophic Cardiomyopathy Without Obstruction
Ann & Robert H Lurie Children's Hospital of Chicago
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease (SGLT2I-IN-KIDS)

Chronic Kidney Diseases | Pediatric Kidney Disease

United States
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
Boehringer Ingelheim

Not yet recruiting

A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure
University of South Carolina

Recruiting

Resistance Exercise and Creatine in Colorectal Cancer

Colorectal Cancer

United States
Ain Shams University

Recruiting

Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease Patients

Chronic Kidney Diseases

Egypt
Jeffrey Zonder

Not yet recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL) (FLORAL)

Renal AL Amyloidosis

United States
HighTide Biopharma Pty Ltd
Shenzhen HighTide Biopharmaceutical Ltd.

Recruiting

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

T2DM (Type 2 Diabetes Mellitus)

China
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan
Beni-Suef University

Not yet recruiting

Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome

Polycystic Ovary

Egypt
China National Center for Cardiovascular Diseases

Recruiting

Use of SGLT2i in noHCM With HFpEF

Hypertrophic Cardiomyopathy | Heart Failure With Preserved Ejection Fraction

China
Sichuan Academy of Medical Sciences

Recruiting

Dapagliflozin Delays the Loss of Renal Function in Peritoneal Dialysis Patients

Peritoneal Dialysis Complication | Renal Function Aggravated | Sodium-glucose Co-transporter-2 Inhibitors

China
The University of Texas Medical Branch, Galveston
ThriveWell Cancer Foundation

Not yet recruiting

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation (THRIVE)

Breast Cancer | Muscle Weakness | Breast Cancer Female

United States
Ankara Etlik City Hospital

Not yet recruiting

Relationship Between Albumin/Creatine Ratio, B12, Folate, and Frailty Index

Frailty Scale

Turkey
Hannover Medical School
Boehringer Ingelheim

Not yet recruiting

Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD) (EMPA-PKD)

Autosomal Dominant Polycystic Kidney
Post Graduate Institute of Medical Education and...

Not yet recruiting

MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin (SHIELD)

Non-Alcoholic Fatty Liver Disease | Hepatic Steato-Fibrosis

India
Chinese University of Hong Kong

Recruiting

SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus

Chronic Hepatitis B

Hong Kong
The People's Hospital of Gaozhou

Recruiting

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

China
Ann & Robert H Lurie Children's Hospital of Chicago

Not yet recruiting

Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease (SHIELD)

Non-Alcoholic Fatty Liver Disease
Matthieu Pelletier-Galarneau, MD MSc

Not yet recruiting

Suppression With Empagliflozin as an Alternative To High-Fat Low-Carbohydrate Diet for Myocardial F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging (SWEET-HEART)

Myocardial Suppression
Samsung Medical Center

Not yet recruiting

The Efficacy of Enavogliflozin in Heart Failure With Preserved Ejection Fraction (ENRICH-PEF)

Heart Failure, Preserved Ejection Fraction

Korea, Republic of
Rennes University Hospital

Not yet recruiting

Medico-economic Evaluation of Robot-assisted Laparoscopy Compared With Conventional Laparoscopy in Hysterectomy for Endometrial Cancer. (ROBOT-ECO-GYN)

Hysterectomies for Low- or Intermediate-risk Endometrial Carcinoma

France
AstraZeneca

Recruiting

Efficacy, Safety and Tolerability of Balcinrenone/Dapagliflozin Compared to Dapagliflozin in Adults With Chronic Kidney Disease. (MIRO-CKD)

Chronic Kidney Disease

Spain, Italy, China, Vietnam, United States, Brazil, Canada, Malaysia, Poland, Taiwan, Austria, Bulgaria, Chile, United Kingdom, Japan
Silesian Centre for Heart Diseases

Recruiting

Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes

Type 1 Diabetes

Poland
RenJi Hospital

Recruiting

Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease

Obesity | Chronic Kidney Diseases

China
Instituto Nacional de Cardiologia Ignacio Chavez

Not yet recruiting

Empagliflozin for No-reflow Phenomenon in PCI for STEMI (EMPA-PCI)

STEMI | No-Reflow Phenomenon
Fondazione IRCCS Policlinico San Matteo di Pavia

Recruiting

Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity (PROTECT)

Breast Cancer

Italy
Handok Inc.

Not yet recruiting

Pharmacokinetics of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers

Healthy Volunteers
International Bio service

Not yet recruiting

Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
Assiut University

Not yet recruiting

SGLT2 Inhibitors and Perioperative Period

Perioperative Complication
Kirby Institute

Not yet recruiting

Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART) (OPTIMAR)

HIV Infections | Weight Gain
Damanhour University
Tanta University

Recruiting

Empagliflozin Versus Vildagliptin in CAD Patients With T2DM

Coronary Artery Disease | Type 2 Diabetes

Egypt
Pharma Nueva

Not yet recruiting

A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers Under Fasting Conditions

Healthy Vollunteer
AstraZeneca

Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function (BalanceD-HF)

Heart Failure and Impaired Kidney Function

Spain, France, Germany, Italy, United States, Argentina, Czechia, Vietnam, Peru, China, Philippines, Saudi Arabia, Australia, Austria, Canada, Japan, Malaysia, Poland, Taiwan, Thailand, Israel, Brazil, Finland, Greece, Mexico, United Kingdom and more
4th Military Clinical Hospital with Polyclinic,...

Recruiting

CardioPROTECTion With Dapagliflozin in Breast Cancer Patients Treated With AnthrAcycline - PROTECTAA TRIAL (PROTECTAA)

Heart Failure | Breast Cancer

Poland
Oswaldo Cruz Foundation
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Recruiting

Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil) (HCVPCL05/20)

Hepatitis C

Brazil
Beijing Chao Yang Hospital
Beijing Boren Hospital; Beijing Chuiyangliu Hospital

Not yet recruiting

Combination of Daratumumab and BD Regimen and Dapagliflozin in the Treatment of M-protein Related Cardiac Disease

M-protein Related Cardiac Disease
IRCCS Fondazione Stella Maris

Recruiting

Optical Imaging as a Tool for Monitoring Brain Function in Creatine Deficiency Syndromes

Creatine Deficiency, X-linked | Creatine Deficiency Syndrome Due to Gamt Deficiency

Italy
University of Michigan
University of Colorado, Denver; Renal Pre-Competitive Consortium (RPC3)

Recruiting

Renal Mechanism of SGLT2 Inhibition

Diabetic Kidney Disease | Type 2 Diabetes

United States

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