Search clinical trials for: De-escalation therapy

Total 51640 results

Shenyang Northern Hospital

Not yet recruiting

OCT or Angiography Guided De-escalation of DAPT

ST Elevation Myocardial Infarction | Dual Antiplatelet Therapy | Optical Coherence Tomography | Antiplatelet De-escalation | Neointimal Coverage

China
Royal North Shore Hospital

Not yet recruiting

De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) (DE-RADIATE)

HPV Positive Oropharyngeal Squamous Cell Carcinoma

Australia
University of Bari Aldo Moro

Not yet recruiting

Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of Pneumonia (SNAP)

Pneumonia, Bacterial
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Hunan Cancer... and other collaborators

Recruiting

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

Nasopharyngeal Carcinoma | De-escalation Therapy

China
Azienda Ospedaliera Universitaria Policlinico "G...
Gianluca Di Bella; Antonio Micari; Giampiero Vizzari; Giorgio Quadri; Greca Zanda; Ferdinando...

Recruiting

De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS (DESC-HBR)

Coronary Artery Disease | Acute Coronary Syndrome | Dual Antiplatelet Therapy

Italy
The Cleveland Clinic

Recruiting

Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia

Community-Acquired Pneumonia | Antimicrobial Stewardship | Point-of-Care Testing

United States
China National Center for Cardiovascular Diseases

Recruiting

Ticagrelor-based De-escalation of Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting (TOP-CABG)

Myocardial Infarction | Myocardial Ischemia | Coronary Artery Disease | Bleeding | Angina Pectoris | Dual Antiplatelet Therapy | Coronary Artery Bypass Grafting

China
Seoul National University Hospital
Ludwig-Maximilians - University of Munich; ST. Antonius hospital Nieuwegein

Recruiting

IPD Meta-analysis of De-escalation Treatment Strategy After PCI in ACS

Coronary Artery Disease | Acute Coronary Syndrome

Korea, Republic of
Technische Universität Dresden
German Cancer Research Center; National Center for Tumor Diseases, Heidelberg; Radiation Oncology Working Group of the German Cancer Society and other collaborators

Recruiting

De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas (DELPHI)

Head-and-neck Squamous Cell Carcinoma

Germany
Northern State Medical University

Completed

The Effect pf Goal-directed De-escalation in ARDS on Organ Function and Mortality

ARDS, Human | Sepsis, Severe

Russian Federation
University Medical Center Groningen
Bühlmann Laboratories AG; European Crohn´s and Colitis Organisation

Enrolling by invitation

De-escalation of Anti-TNF Therapy in Inflammatory Bowel Disease (FREE)

Inflammatory Bowel Diseases | Crohn Disease | Colitis, Ulcerative

Belgium, Netherlands, Spain
Catharina Ziekenhuis Eindhoven
Erasmus Medical Center

Completed

Mean Systemic Filling Pressure Continuous Diuretics Critical Care Patients

Heart Diseases | Heart Failure | Sepsis | Septic Shock | Surgery | Critically Ill

Netherlands
University Hospital, Ghent

Completed

DetermInants of Antimicrobial Use aNd De-escalAtion in Critical Care (DIANA) (DIANA)

Infection

Belgium
Washington University School of Medicine

Completed

Pneumonia in the Intensive Care Unit (ICU) Setting

Pneumonia | Respiratory Failure

United States
Assistance Publique Hopitaux De Marseille

Completed

De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis

Severe Sepsis

France
Winthrop University Hospital

Completed

Use Of Procalcitonin Level For Guidance of The Treatment of Suspected Community Acquired Pneumonia

Pneumonia | Radiographic Lung Infiltrates

United States
Osaka University
Japan Agency for Medical Research and Development

Recruiting

Clinical Trial of Targeted Alpha Therapy for Prostate Cancer (Alpha-PS1)

Prostate Cancer

Japan
University of Michigan Rogel Cancer Center

Not yet recruiting

Self-Administered Relaxing Acupressure to Reduce Fatigue in Adolescent and Young Adult Cancer Survivors

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Ain Shams University

Recruiting

Clinical Outcome of Vinpocetine in Diabetic Nephropathy

Diabetic Kidney Disease | Diabetic Nephropathies

Egypt
NYU Langone Health

Not yet recruiting

Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis

Acute Bronchiolitis

United States
Uppsala University

Not yet recruiting

A Metacognitive Group Therapy of Depression and Anxiety in Youth With Autism

Anxiety Depression

Sweden
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)

Chronic Pain | Opioid Withdrawal

United States
Accelerated Cure Project for Multiple Sclerosis
Charite University, Berlin, Germany; United States Department of Defense; US... and other collaborators

Not yet recruiting

Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis (CAFE-MS)

Multiple Sclerosis | Fatigue
University of Palermo

Recruiting

Effectiveness of Extracorporeal Shockwave Therapy and Nutraceutical Supplementation in the Treatment of Epicondylitis: a Clinical Trial

Tennis Elbow | Epicondylitis, Lateral | Epicondylitis of the Elbow

Italy
University of Illinois at Chicago

Not yet recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer (BRE-10)

Breast Cancer | HER2-positive Breast Cancer
Foundation University Islamabad

Recruiting

Effects of Intra Muscular Electrotherapy Combined With Manipulative Therapy in Patients With Sacral Torsion

Sacroiliac Joint Dysfunction

Pakistan
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Waldenström's Macroglobulinemia (WM)

Italy
Matthew R. Hoffman

Not yet recruiting

Characterizing the Impact of Presbyphonia on Social Interaction

Presbyphonia
Northwestern University

Not yet recruiting

Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder

REM Sleep Behavior Disorder | Nightmare | Nightmare Disorder With Associated Other Sleep Disorder

United States
Astellas Pharma Global Development, Inc.

Not yet recruiting

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy

Hot Flashes
Regina Elena Cancer Institute

Recruiting

Low Intensity Shock Wave Therapy in the Rehabilitation Treatment of Erectile Dysfunction After Robotic Radical Prostatectomy.

Erectile Dysfunction

Italy
ITM Solucin GmbH

Not yet recruiting

Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors (KinLET)

Lymphoma | CNS Tumor | Solid Tumor, Childhood | Somatostatin Receptor Positive | NET
Centre Henri Becquerel

Not yet recruiting

Contribution of the VERITON-CT Camera in Prostate Bone Radiostereotaxy (VERIOS)

Prostatic Cancer

France
Virginia Commonwealth University

Not yet recruiting

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial (CBT-I in PBT)

Glioblastoma | Astrocytoma | Oligodendroglioma | Meningioma | Primary Brain Tumor | Primary Central Nervous System (CNS) Lymphoma

United States
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Diffuse Large B Cell Lymphoma

Spain
Taif University

Not yet recruiting

Effects of Lymph Drainage on Patients With Axillary Web Syndrome

Movement Disorders
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (SPARKLE)

Sickle Cell Disease
Main Line Health
Pfizer; Sumitomo Pharma America, Inc.

Not yet recruiting

The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial

Endometriosis

United States
University of Alabama at Birmingham

Not yet recruiting

Role of Combination Therapy in Women With Refractory Overactive Bladder

Overactive Bladder Syndrome
Clinical Hospital Centre Zagreb

Not yet recruiting

Therapeutic Options for CRAB (TheraCRAB)

Infections, Bacterial | Sepsis Bacterial
Indonesia University

Recruiting

The Role of Thread Embedding Acupuncture for Pain and Quality of Life in Endometriosis Patients

Endometriosis-related Pain

Indonesia
University Hospital, Bordeaux
Baxter Healthcare Corporation

Not yet recruiting

Immunothrombosis With Septic Shock Undergoing Renal Replacement Therapy With the OXIRIS Membrane (PLAQSIRIS)

Sepsis

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer (LySATRA)

Solid Tumor, Adult | Oligometastatic Disease

France
Dana-Farber Cancer Institute
Johns Hopkins University; Translational Breast Cancer Research Consortium

Not yet recruiting

The SAPPHO Study: A Single-Arm, Phase II Study of Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Breast Cancer | HER2-positive Breast Cancer | Stage IV Breast Cancer | Breast Cancer Female | Breast Cancer Metastatic | Estrogen Receptor-positive Breast Cancer

United States
Foundation University Islamabad

Recruiting

Effects of Sustained Natural Apophyseal Glides Combined With Kinesiotaping in Patients With Chronic Mechanical Neck Pain: A Randomised Controlled Trial

Neck Pain

Pakistan
Tianjin Medical University Cancer Institute and...
Kingbio Medical (Beijing) Co., Ltd.

Not yet recruiting

Clinical Treatment of Refractory Breast Cancer Based on Organoid Drug Sensitivity Results

Refractory Breast Cancer
Foundation University Islamabad

Recruiting

Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome

Piriformis Syndrome

Pakistan
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Glenzocimab in Anterior Stroke With Large Ischemic Core Eligible for Endovascular Therapy (GALICE)

Acute Ischemic Stroke
Nigde Omer Halisdemir University
Selcuk University

Not yet recruiting

The Effectiveness of Two Different Methods in Heel Blood Collection

Pain | Infant Behavior
Foundation University Islamabad

Recruiting

"Effects of Passive Static Stretching of 30 Seconds Versus 60 Seconds on the Hamstring Flexibility in Adults With Hamstring Tightness.

Hamstring Flexibility

Pakistan

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