Search clinical trials for: Dose Limiting Toxicity

Total 22439 results

GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use (ROLDI)

Opioid Use Disorder
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Colorectal Neoplasia

United States
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
University of Melbourne

Not yet recruiting

Dose-Response Effects of Mindfulness Meditation

Depression | Well-Being, Psychological
Fundació Eurecat
Centre de Diagnosi per la Imatge; Instituto de Investigación Biomédica de Girona... and other collaborators

Not yet recruiting

Effect of Multi-ingredient on Visceral Adiposity & Non-alcoholic Fatty Liver Disease in Postmenopausal Women With Abdominal Obesity (FATHIS+)

Visceral Obesity | Non-alcoholic Fatty Liver | Postmenopausal

Spain
Amgen

Not yet recruiting

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

Asthma
AstraZeneca

Recruiting

Lung Cancer Screening Program Using Low-dose Tomography and Metabolomic Evaluation in a Public Service.

Lung Cancer

Brazil
Dokuz Eylul University

Not yet recruiting

Sequential Intravesical Gemcitabine and Docetaxel for Rescue Therapy in BCG Unresponsive Non-muscle Invasive Bladder Cancer Patients

Bladder Cancer | Gemcitabine | BCG | Docetaxel | Intravesical Instillation

Turkey
Lidian Chen
Peking University Third Hospital

Not yet recruiting

Efficacy of Different Doses of Tai Chi Chuan on Cognitive Function in Persons With Mild Cognitive Impairment

Mild Cognitive Impairment
Lidian Chen
Peking University Third Hospital

Not yet recruiting

Effects of Tai Chi Chuan With Different Doses on Cognitive Function in Elderly Patients With Mild Cognitive Impairment

Mild Cognitive Impairment
VarmX B.V.

Recruiting

Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant

Coagulation Disorder

Netherlands
Closed Loop Medicine
Pharmanovia

Recruiting

Personalised Dose Optimisation of Zestril Supported by the Digital Blood Pressure Diary in a Primary Care Environment in England: Pragmatic Observational Pilot Study for Remote Hypertension Treatment (OptiZest)

Uncomplicated Hypertension

United Kingdom
Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Not yet recruiting

A Single Dose Escalation Study of HHT201 in Healthy Subjects

Alzheimer Disease

China
Hao Tang

Recruiting

Deep Learning Reconstruction Algorithms in Dual Low-dose CTA

Deep Learning

China
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Ting Chang, MD

Not yet recruiting

Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis

Myasthenia Gravis

China
Eilean Therapeutics

Not yet recruiting

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia

AML With Gene Mutations

Australia
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
Jessica Merlin
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (TREETOP)

Chronic Pain | Opioid Use Disorder

United States
Brigham and Women's Hospital
Open Medicine Foundation

Not yet recruiting

LIFT: Life Improvement Trial (LIFT)

ME/CFS
University of California, Berkeley

Not yet recruiting

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

Aging
Universidad Peruana Cayetano Heredia
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis

Fascioliasis
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
CT Glaucoma Associates

Recruiting

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Glaucoma, Open-Angle | Glaucoma; Drugs

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Bladder Cancer

China
Astellas Pharma Inc

Recruiting

A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Solid Tumor

United States
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
ITB-Med LLC

Recruiting

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Kidney Transplantation

Spain, Sweden, Austria
Kylonova (Xiamen) Biopharma co., LTD.

Recruiting

Dose Escalation Study of Kylo-0603 in Healthy Subjects

Nonalcoholic Steatohepatitis

China
University Health Network, Toronto

Not yet recruiting

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction (ULTRAS)

Liver Metastases
Anhui Provincial Hospital

Not yet recruiting

The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT

High Titers of Anti-HLA Antibody (MFI ≥5000)

China
Laboratorios Sophia S.A de C.V.

Recruiting

Study to Evaluate the Safety and Tolerability of PRO-231 Ophthalmic Solution Versus VIGAMOXI® on the Ocular Surface of Healthy Subjects.

Bacterial Conjunctivitis | Ophthalmological Agent Toxicity

Mexico
Sonoma Biotherapeutics, Inc.

Recruiting

Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above

Influenza Immunization

United States, Puerto Rico
Kylonova (Xiamen) Biopharma co., LTD.

Not yet recruiting

Single-ascending Dose Study of Kylo-11 in Healthy Subjects

Cardiovascular Diseases

China
Tanta University

Not yet recruiting

Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy

Dexmedetomidine | Splenectomy | External Oblique Intercostal Plane Block

Egypt
Zhejiang Hanmai Pharmaceutical Technology Co.,...

Not yet recruiting

Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of YJ001 for Spray Use in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States
The Hong Kong Polytechnic University
The University of Hong Kong

Not yet recruiting

Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control

Myopia

Hong Kong
Peking University

Not yet recruiting

A Dose-response Study to Validate the Biomarkers for Whole Grain Dietary Intake

Chronic Disease Prevention

China
University of Zurich

Recruiting

Ultra Low Dose CT and Use of Iomeron 400 in PCD-CT

Pneumonia | Lung Cancer | Radiation Exposure | Lung Embolism

Switzerland
Assiut University

Not yet recruiting

Efficacy and Toxicity of Docetaxel as a Radiosenstizer in Head and Neck Cancer

Head and Neck Cancer
Xinhua Hospital, Shanghai Jiao Tong University...

Recruiting

PEELED INTERNAL LIMITING MEMBRANE REPOSITION

Macular Holes

China
KARANAHAN

Recruiting

Clinical Study of Personalized Chemotherapy for Breast Cancer With Low Doses of Cyclophosphamide

Stage IV Breast Cancer

Russian Federation
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance in Age

Aging

France
OHSU Knight Cancer Institute
Oregon Health and Science University; Oryzon Genomics S.A.

Not yet recruiting

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndrome/Acute Myeloid Leukemia

United States
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Central Hospital, Nancy, France
University Hospital, Strasbourg, France; CHU de Reims; European Georges Pompidou... and other collaborators

Recruiting

Role of Renal Biopsy in the Suspicion of Nephrotoxicity of Immunotherapy (Checkpoint Inhibitors) in Solid Cancer (NEPHROTOX)

Chemotherapeutic Toxicity

France
Ohio State University

Not yet recruiting

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Movement Disorders | Aging | Behavior | Dementia With Lewy Bodies | Emergency Psychiatric | Cognition Disorder | Antipsychotics and Neuroleptics Toxicity | Alteration in Mental Status

Search clinical trials for: Dose Limiting Toxicity

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