Search clinical trials for: Double blinded randomized clinical trial

Total 87851 results

University of Seville

Recruiting

Differents Laser Applications on Plantar Fasciitis

Fasciitis, Plantar

Spain
Novartis Pharmaceuticals

Recruiting

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Chronic Spontaneous Urticaria

United States, Singapore, Spain, Germany, Turkey, Italy, Hong Kong, China, Argentina, Malaysia, Thailand, Poland, Japan, Netherlands, South Africa, Chile, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

Colorectal Cancer | Lynch Syndrome | T Cells

United States
RenJi Hospital

Recruiting

A Prospective, Randomized, Double-blinded, Multi-center Clinical Trial to Evaluate the Efficiency and Safety of Anti-PD1 Antibody (Camrelizumab) Combined With Paclitaxel(Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer Metastatic | Pancreatic Cancer Stage IV

China
General Committee of Teaching Hospitals and Institutes...

Active, not recruiting

A Comparative Study Between Ultrasound Guided Shoulder Block and Pericapsular Nerve Group Bock for Shoulder Arthroscopic Surgeries: Double Blinded Randomized Clinical Trial

Efficacy of PENG Block Managing Perioperative Pain With Shoulder Arthroscopy Surgeries | Efficacy of Shoulder Block in Managing Perioperative Pain With Shoulder Arthroscopy Surgeries

Egypt
National Institute of Allergy and Infectious Diseases...

Completed

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

Zika Virus Infection

United States
Rigshospitalet, Denmark

Terminated

A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial

Hypogonadotropic Hypogonadism | Hypogonadism | Hypogonadism, Male

Denmark
International AIDS Vaccine Initiative
Massachusetts General Hospital; GlaxoSmithKline; Fred Hutchinson Cancer Research... and other collaborators

Completed

A Randomized, Double-blinded, Placebo-controlled, Dose-escalation Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV Envelope Protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in Healthy, HIV-1 Uninfected Adults

HIV Infections

United States, Kenya
Chung Shan Medical University

Completed

Soft Peripheral Contact Lens for Eye Elongation Control (SPACE):1-year Results of a Double-blinded Randomized Con-trolled Trial

Soft Contact Lens

Taiwan
Yu Qin

Active, not recruiting

An Investigator Initiated, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Safety, Immunogenicity and Efficacy of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) in Adults Aged 18 Years and Older

Prevention of COVID-19 Caused by SARS-CoV-2

China
NovaCell Technology Inc.

Completed

A Single-center, Randomized, Double-blinded, Placebo-controlled, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of NCP112

Atopic Dermatitis

Korea, Republic of
Globe Biotech Limited

Completed

A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002

Natural Blood and Blood Product Toxicity

Bangladesh
prof. dr. Jan Deprest

Completed

Use of Fractional CO2 Laser for the Treatment of Vulvovaginal Atrophy: a Double-blinded Randomized Placebo-controlled Clinical Trial. (CO2VVA)

Vulvovaginal Atrophy

Belgium
Gachon University Gil Oriental Medical Hospital
Kyung Hee University Hospital at Gangdong; Kyunghee University Medical Center; Sangji University Oriental Medical Hospital and other collaborators

Completed

Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial

Cold Hypersensitivity

Korea, Republic of
Uniformed Services University of the Health Sciences
U.S. Army Medical Research and Development Command

Completed

Safety Study of Riluzole to Treat Post-traumatic Stress Disorder (PTSD)

PTSD

United States
Gachon University Gil Oriental Medical Hospital
DongGuk University; Sangji University Oriental Medical Hospital, Korea

Completed

A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -

Obesity | Metabolic Syndrome

Korea, Republic of
BioGaia AB

Completed

Double-blinded, Randomized, Placebo-controlled Study Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection

Recurrent Urinary Tract Infection in Adult Women

Sweden
Kristian Kiim Jensen

Completed

PreOperative Steroid in Abdominal Wall Reconstruction: A Double-blinded Randomized Clinical Trial (POSAR)

Hernia, Ventral

Denmark
Odense University Hospital

Completed

Acupuncture as Treatment of Post-herpetic Neuralgia: A RCT A Double-blinded Randomized Clinical Trial.

Post Herpetic Neuralgia

Denmark
Hong Kong Baptist University
Queen Elizabeth Hospital, Hong Kong; Prince of Wales Hospital, Shatin, Hong...

Completed

A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation

Functional Constipation | Gastrointestinal Disorders

China
University of Alberta

Terminated

KITS Study -Ketorolac In Tonsillectomy Surgery: a Double Blinded, Randomized Clinical Trial (KITS)

Recurrent Acute Tonsillitis

Canada
Hospital San Carlos, Madrid

Completed

Deep-brain Stimulation in Obsessive-compulsive Disorder: Randomized, Double-blinded Clinical Trial (10/131)

Obsessive-Compulsive Disorder
Bundang CHA Hospital

Unknown

Clinical Trial to Evaluate the Potential Efficacy and Safety of Human Umbilical Cord Blood and Plasma

Aging

Korea, Republic of
Mayo General Hospital, Ireland

Unknown

Lap TAP Block for Laparoscopic TEP Inguinal Hernia Repair: a Prospective, Double-blinded, Randomized, Clinical Trial

Laparoscopic TAP Block in TEP Inguinal Hernia Repair.

Ireland
Medical University of Vienna

Completed

A Prospective Randomized Double-Blinded Placebo Controlled, Explorative Phase I Trial to Investigate the Safety and Tolerability of Two Different Doses of Topically Administered APOSEC™ in Healthy Male Subjects With Artificial Dermal Wounds

Healthy | Artificial Dermal Wound

Austria
University of Messina

Completed

Wearable Pulsed Electromagnetic Fields Device in Knee Osteoarthritis: Double Blinded, Randomized Clinical Trial

Knee Osteoarthritis

Italy
University Hospital, Clermont-Ferrand

Completed

Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial (ELVIS)

Acute Renal Failure | Infection

France
Photocure

Completed

A Double Blinded, Prospective, Randomized, Vehicle Controlled Multi-center Study of Photodynamic Therapy With Visonac® Cream in Patients With Acne Vulgaris

Acne Vulgaris

United States
Hvidovre University Hospital

Completed

Ultrasound Guided Transversus Abdominis Plane Block With Ropivacaine vs Placebo for Abdominal Hysterectomy: a Double-blinded, Randomized Clinical Trial

Postoperative Pain and Postoperative Morphine Consumption After Abdominal Hysterectomy

Denmark
Twin Star Medical, Inc.
United States Department of Defense

Unknown

Double Blinded, Randomized Clinical Trial of the Twin Star ECSPRESS Monitoring System for the Reduction of the Incidence of Fasciotomy (ECSPRESS)

Compartment Syndrome

United States
Rigshospitalet, Denmark

Completed

The Analgesic Effect of Transversus Abdominis Plane (TAP) Block Following Radical Prostatectomy

Postoperative Pain

Denmark
Intercell USA, Inc.

Completed

Prevention, Randomized, Double-Blinded, Placebo-Controlled, Parallel Assignment, Safety/Efficacy Study

Traveler's Diarrhea

United States
Charite University, Berlin, Germany
University of Jena

Completed

n-3 and n-6 Fatty Acids in Rheumatoid Arthritis

Rheumatoid Arthritis
University Hospital Dubrava
Ministry of Science, Education and Sport, Republic of Croatia

Unknown

Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer

Colonic Neoplasms

Croatia
Sinovac Biotech Co., Ltd
Ministry of Science and Technology of the People´s Republic of China

Completed

Randomized, Double Blinded, Placebo Control Clinical Trial of Pandemic Influenza Inactive Vaccine on Healthy Subjects

Influenza

China
University of Aarhus
Aarhus University Hospital; University of Copenhagen; Gødstrup Hospital; Statens... and other collaborators

Not yet recruiting

The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial (BEGIN)

Healthy | Healthy Nutrition
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial

Acute Ischemic Stroke

China
AQTIS Medical B.V.

Not yet recruiting

A Prospective, Randomized, No-treatment Controlled, Evaluator-blinded Clinical Trial to Evaluate the Efficacy and Safety of Polycaprolactone Microspherical Injectable to Improve Forehead Contour

Forehead Contouring

China
Potsawat Surabotsopon

Not yet recruiting

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial (MIS-TLIF)

Surgery | Disc Degeneration | Spinal Stenosis Lumbar | Fusion of Spine | Disc Disease
Foresee Pharmaceuticals Co., Ltd.
InClin, Inc.

Recruiting

Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers

Healthy

Australia
Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
Le Yu

Recruiting

Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial

Anesthesia

China
Universidad de Colima

Recruiting

Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics (FAPD_RCT)

Functional Gastrointestinal Disorders | Functional Abdominal Pain Syndrome | Irritable Bowel Syndrome Variant of Childhood

Mexico
University Hospital, Tours
Hospices Civils de Lyon; Centre Hospitalier Universitaire Dijon; CHU de Reims; University... and other collaborators

Not yet recruiting

Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial (CARVECIR)

Clinically Significant Portal Hypertension | Asymptomatic Cirrhosis

France
Hacettepe University

Recruiting

Clinical Investigation of Effectiveness of a Calcium Silicate Cement

Deep Caries | Dentin Caries

Turkey
Sun Yat-sen University

Recruiting

A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)

Recurrent or Metastatic Nasopharyngeal Carcinoma

China
Sohag University

Not yet recruiting

Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial

Post Spinal Anesthesia Hypotension
Chang Gung Memorial Hospital

Not yet recruiting

Preoperative Daptomycin Prophylaxis in Two-Stage Exchange Arthroplasty: A Prospective, Randomized, Double-Blinded Trial

Periprosthetic Joint Infection

Taiwan
Beijing Tiantan Hospital

Not yet recruiting

Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis (SPECIALS)

Amyotrophic Lateral Sclerosis

China
LB Pharmaceuticals Inc.

Recruiting

Randomized, Double-blinded, Placebo-controlled, Evaluating the Treatment With LB-102 in Patients With Acute Schizophrenia

Schizophrenia

United States

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