Search clinical trials for: Early treatment

Total 71829 results

Washington University School of Medicine
Eli Lilly and Company; Hoffmann-La Roche; Avid Radiopharmaceuticals; National Institute... and other collaborators

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001 (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, Argentina, Australia, Colombia, France, Ireland, Mexico, Netherlands, Puerto Rico, Spain, United Kingdom, Brazil, Japan, Germany
National Cancer Institute (NCI)

Not yet recruiting

Biomarkers in Predicting Treatment Response in Samples From Patients With Early-Stage Non-Small Cell Lung Cancer Previously Treated With Adjuvant Chemotherapy

Stage IIIA Non-small Cell Lung Cancer | Stage IA Non-small Cell Lung Cancer | Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer

Canada
Sunnybrook Health Sciences Centre

Recruiting

Ultrasound Imaging, Spectroscopy and Ultrasound Imaging of Vascular Blood Flow as Early Indicators of Breast Cancer Response to Neoadjuvant Treatment.

Breast Cancer Invasive

Canada
National Cancer Institute (NCI)
NRG Oncology

Suspended

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Squamous Cell Carcinoma | Basaloid Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Papillary Squamous Cell Carcinoma | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States, Canada
Eli Lilly and Company

Active, not recruiting

A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

Alzheimer Disease

United States, Canada, Australia, Japan, Poland, Puerto Rico, Czechia, Netherlands, United Kingdom
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Endometrial Endometrioid Adenocarcinoma | Stage I Uterine Corpus Cancer AJCC v8 | Stage II Uterine Corpus Cancer AJCC v8

United States, Puerto Rico
Alzheon Inc.
National Institute on Aging (NIA)

Active, not recruiting

An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects (APOLLOE4)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
University of Minnesota
University of Colorado, Denver; Northwestern University; Olive View-UCLA Education... and other collaborators

Completed

COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

Covid19 | SARS-CoV Infection

United States
Alzheon Inc.

Enrolling by invitation

Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects (APOLLOE4-LTE)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
Janssen Research & Development, LLC

Active, not recruiting

A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease (Autonomy)

Cognitive Dysfunction | Dementia | Alzheimer Disease

United States, Belgium, France, Japan, United Kingdom, Spain, Canada, Australia, Sweden, Netherlands
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Diseases | Atherosclerosis | Hypertriglyceridemia

United States, Spain, Italy, Denmark, Hungary, Netherlands, Canada, France, Poland, Bulgaria, Czechia, Portugal, Slovakia, Norway
Novartis Pharmaceuticals

Active, not recruiting

Study to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls. (AGNOS)

Relapse Remitting Multiple Sclerosis

United States, Puerto Rico
MacroGenics

Active, not recruiting

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Colorectal Cancer | Advanced Cancer | Prostate Cancer Metastatic | Cutaneous Melanoma | Solid Tumor, Adult | Squamous Cell Non Small Cell Lung Cancer

United States, Spain, Bulgaria, Poland, Ukraine
IRCCS Azienda Ospedaliera Universitaria San Martino...
Clinical Research Technology S.r.l.

Active, not recruiting

CONcurrent vs SEqueNTial Adjuvant Treatments in Early Breast Cancer (GIM10-CONSENT)

Breast Cancer

Italy
IrsiCaixa
Hospital Clinic of Barcelona; University of Oxford; Germans Trias i Pujol Hospital and other collaborators

Completed

Study to Evaluate the Safety and Effect of HIVconsv Vaccines in Combination With Histone Deacetylase Inhibitor Romidepsin on the Viral Rebound Kinetic After Treatment Interruption in Early Treated HIV-1 Infected Individuals

HIV

Spain
Arvinas Inc.
Pfizer

Active, not recruiting

A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery

Breast Cancer

United States, Spain, Germany, Georgia
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH); Columbia University; New York State...

Completed

Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia

Schizophrenia Spectrum and Other Psychotic Disorders

United States
Advancing Clinical Therapeutics Globally for HIV...
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Early ART to Limit Infection and Establishment of Reservoir (EARLIER)

HIV-1 Infection

United States, Brazil, Malawi, Zimbabwe, Thailand, Peru
Asan Medical Center

Active, not recruiting

Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation

Mitral Regurgitation

Korea, Republic of
New York State Psychiatric Institute
National Institute of Mental Health (NIMH); Northwell Health, Early Treatment... and other collaborators

Completed

Using mHealth to Optimize Pharmacotherapy Regimens

Schizophrenia | First-Episode Psychosis

United States
National Cancer Institute (NCI)

Terminated

Early Detection of Esophageal Cancer

Stomach Neoplasms | Esophageal Neoplasms | Endoscopy, Gastrointestinal | Cytology | Digestive System Endoscopic Surgical Procedures

China
University of California, Los Angeles
W.L.Gore & Associates

Active, not recruiting

Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents

Ascites | Hypertension, Portal

United States
Novo Nordisk A/S

Active, not recruiting

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

Early Alzheimer's Disease

Canada, United States, Spain, Netherlands, United Kingdom, Austria, Korea, Republic of, Portugal, Italy, Australia, Argentina, Hungary, Germany, Brazil, Poland, Denmark, Czechia, Ireland, Norway, Japan, Romania, South Africa, Sweden, ... and more
Novo Nordisk A/S

Active, not recruiting

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

Early Alzheimer´s Disease

Canada, United States, Taiwan, Netherlands, United Kingdom, Spain, Austria, Korea, Republic of, Portugal, Italy, Australia, Argentina, Hungary, Germany, Brazil, China, Poland, Denmark, Czechia, Ireland, Japan, South Africa, Romania, S... and more
Memorial Sloan Kettering Cancer Center
Astellas Pharma Inc; Medivation, Inc.

Active, not recruiting

Feasibility Study of Adjuvant Enzalutamide for the Treatment of Early Stage AR (+) Triple Negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer | Early Stage

United States
AstraZeneca
Daiichi Sankyo

Active, not recruiting

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Breast Cancer | Breast Neoplasms | HER2-positive Early Breast Cancer

United States, Italy, Spain, Poland, Taiwan, Thailand, Canada, Germany, Korea, Republic of, Brazil, India, Japan, Peru, Philippines, China, Saudi Arabia, Russian Federation, Bulgaria
Oslo University Hospital
Norwegian Cancer Society; Klinbeforsk

Active, not recruiting

Establishment of Molecular Profiling for Individual Clinical Routine Treatment Decision in Early Breast Cancer (EMIT)

Breast Cancer | Breast Neoplasms | Hormone Receptor Positive Tumor

Norway
ETOP IBCSG Partners Foundation
Alliance for Clinical Trials in Oncology; Canadian Cancer Trials Group; Breast...

Active, not recruiting

Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer (POSITIVE)

Early Breast Cancer

Korea, Republic of, United States, France, Canada, Spain, Lebanon, Belgium, Switzerland, Israel, Ireland, Japan, Italy, Denmark, Austria, Australia, Greece, Hungary, Netherlands, Norway, Portugal, Serbia, Slovenia
Jazz Pharmaceuticals

Available

An Expanded Access Treatment Protocol of Zanidatamab (ZW25) in Patients With HER2-Positive Advanced Biliary Tract Cancer

HER2-Positive Advanced Biliary Tract Cancer

Spain, United States, France, Italy, United Kingdom
Organon and Co

Completed

Study to Test Rizatriptan in the Early Treatment of Acute Migraine (0462-081)

Migraine
Oncology Institute of Southern Switzerland

Active, not recruiting

Identification of Biomarkers That Are Predictive of Early Ibrutinib Treatment Failure in High Risk TP53 Mutated Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Italy, Switzerland
Region Stockholm

Active, not recruiting

Safe Prescription of Opioids in Primary Care

Opioid-Related Disorders | Narcotic-Related Disorders | Addiction

Sweden
Qilu Pharmaceutical Co., Ltd.

Completed

Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive and Estrogen Receptor/Progesterone Receptor Negative Breast Cancer to Evaluate the Efficiency and Safety of Treatment With Trastuzumab Plus (+) QL1209/Pertuzumab + Docetaxel.

Breast Cancer

China
University of Florida

Suspended

Novel RNA-nanoparticle Vaccine for the Treatment of Early Melanoma Recurrence Following Adjuvant Anti-PD-1 Antibody Therapy

Melanoma

United States
Temple University
National Institute of Mental Health (NIMH)

Completed

Facilitating Engagement in Evidence-Based Treatment for Early Psychosis

Psychotic Disorders

United States
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer (ProHer)

Inflammatory Breast Cancer | Early Breast Cancer | Locally Advanced Breast Cancer

Canada, Croatia, Spain, Argentina, Mexico, Korea, Republic of, Bosnia and Herzegovina, Brazil, Costa Rica, Turkey, Singapore, Bulgaria, South Africa, India, Peru, Kenya, Chile
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Enrolling by invitation

Enhancing Skin Cancer Early Detection and Treatment in Primary Care

Cutaneous Melanoma

United States
Beijing Tiantan Hospital
National Natural Science Foundation of China

Enrolling by invitation

An Early Warning Model of Unfavorable Outcomes Following Endovascular Interventional Treatment of Intracranial Aneurysm

Intracranial Aneurysm

China
AstraZeneca

Active, not recruiting

Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment (EMERALD-2)

Hepatocellular Carcinoma

United States, France, Germany, Italy, Canada, Taiwan, Thailand, Vietnam, Korea, Republic of, Brazil, Japan, Peru, Poland, Russian Federation, Turkey, China, Hong Kong, Puerto Rico, Austria, Australia, India, Philippines, Singapore, E...
Weill Medical College of Cornell University
Fogarty International Center of the National Institute of Health; Haitian Group...

Completed

Treatment of Early Hypertension Among Persons Living With HIV in Haiti

HIV/AIDS | Pre Hypertension

Haiti
Bristol-Myers Squibb

Active, not recruiting

A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Russian Federation, Belgium, United States, Australia, Argentina, Brazil, Canada, China, Czechia, France, Germany, Ireland, Italy, Japan, Mexico, Netherlands, Poland, Puerto Rico, Romania, Spain, Taiwan, United Kingdom
Landspitali University Hospital

Active, not recruiting

The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses

Antibiotic Treatment | Immune Responses

Iceland
Virginia Commonwealth University

Completed

SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI)

COVID-19 | Kidney Injury | Lung Injury, Acute

United States
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI); University of Copenhagen; US... and other collaborators

Completed

Vaccination for Recovered Inpatients With COVID-19 (VATICO)

Covid19

United States, Spain, Uganda, Nigeria, Singapore, Switzerland
Hoffmann-La Roche

Terminated

A Study to Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

Alzheimer Disease

Belgium, United States, Poland, Spain, Germany, Italy, France, United Kingdom
Bond Avillion 2 Development LP
Parexel

Active, not recruiting

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

Asthma

United States
AO Innovation Translation Center

Active, not recruiting

Evaluation of a Modern System to Allow for Growth in Children With Scoliosis Versus a Conventional Treatment

Early Onset Scoliosis

United Kingdom, Switzerland
Metro International Biotech, LLC

Completed

Phase 2a MIB-626 vs. Placebo COVID-19

Covid19 | Stage 1 Acute Kidney Injury

United States
Chiesi Canada Corp

Completed

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children (START)

Iron Overload | Beta Thalassemia Major Anemia

Egypt, Indonesia
University of Wisconsin, Madison

Suspended

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer (MAPBI)

Breast Cancer | DCIS | LCIS

United States

Search clinical trials for: Early treatment

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Georgia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations