Search clinical trials for: Environmental Challenge Chamber

Total 3437 results

ALK-Abelló A/S

Terminated

A Research Study in Chinese People With Allergy to House Dust Mites, Using an Environmental Exposure Chamber (QUEST)

Allergic Rhinoconjunctivitis

Austria, China
Gilead Sciences

Completed

Study to Investigate Effects of CAL-101 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber

Allergic Rhinitis

Austria
GlaxoSmithKline

Completed

Effects Of Single Doses Of GW784568X On Allergic Rhinitis Symptoms In Male Subjects Whilst In An Environmental Chamber

Rhinitis, Allergic, Perennial

Germany
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Cat Pilot Study - Environmental Exposure Chamber (EEC) vs. Nasal Allergen Challenge (NAC)

Hypersensitivity, Immediate

Canada
ALK-Abelló A/S

Completed

Evaluation of the Efficacy and Safety of AVANZ® Phleum Pratense in Grass Pollen-induced Allergic Rhinitis During Controlled Exposure in an Environmental Challenge Chamber (AV-G-03)

Grass Pollen Induced Allergic Rhinoconjunctivitis

Germany
Boehringer Ingelheim

Completed

Randomized, Placebo Controlled, Crossover Study in an Environmental Challenge Chamber to Assess Safety & Efficacy of Three Oral Doses of BI 671800 Versus Fluticasone Propionate and Montelukast in Sensitive Seasonal Allergic Rhinitis Patients Out of Season

Asthma | Rhinitis, Allergic, Seasonal

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)

Seasonal Allergic Rhinitis
Faes Farma, S.A.

Completed

A Randomized, Double-Blind, 4-way Crossover Study to Evaluate the Efficacy of Bilastine in the Vienna Challenge Chamber

Seasonal Allergic Rhinitis

Austria
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Validation of an Environmental Exposure Chamber for Inhalation Studies With House Dust Mite Allergen in Patients With Allergic Rhinitis

Allergy to House Dust Mite

Germany
Gilead Sciences

Completed

Study to Investigate Effects of CAL-263 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber

Allergic Rhinitis

Austria
The University of Texas Health Science Center at...
National Institute of Allergy and Infectious Diseases (NIAID); Regeneron Pharmaceuticals

Recruiting

Dupilumab Effects Against Aeroallergen Challenge

Asthma, Allergic

United States
Johann Wolfgang Goethe University Hospital

Recruiting

Epigenetic Regulation of Exercise Induced Asthma

House Dust Mite Allergy | Exercise Induced Asthma

Germany
King Abdulaziz University

Not yet recruiting

The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients

COVID-19

Saudi Arabia
Medical College of Wisconsin

Recruiting

The Feasibility and Examination of the Effects of Floatation-based REST on a Community Sample With PTSD (FLOAT)

Post-Traumatic Stress Disorders

United States
RAI Services Company

Completed

CSD200902: Assessment of Indoor Air Quality for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Environmental Testing Chamber

Smoking | Tobacco Use | Tobacco Smoking

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Safety and Efficacy of Low-dose IL-2 in Birch Pollen Allergy (Rhinil-2)

Allergic Rhinoconjunctivitis to Birch Pollen | With a Positive Skin Prick Test to Birch Pollen

France
UNICANCER
Pfizer

Active, not recruiting

PAlbociclib and Circulating Tumor DNA for ESR1 Mutation Detection (PADA-1)

Metastatic Breast Cancer

France
Centre des Sciences du Goût et de l'Alimentation

Completed

Evaluation of the "Eat Less Meat" One-month Challenge

Diet, Healthy | Food Habits

France
Merck Sharp & Dohme LLC

Active, not recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)

Non-small Cell Lung Cancer

United States, Argentina, Australia, Belgium, Brazil, Canada, China, Estonia, France, Germany, Ireland, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Poland, Romania, Russian Federation, South Africa, Spain, Taiwan, U... and more
University of Rochester
Bausch & Lomb Incorporated

Completed

Objective Evaluation of Ocular Surface Lubricants in Two Environments

Dry Eye

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Screening Inhaled Allergen Challenge for Dermatophagoides Farinae (MiteScreen)

Asthma

United States
Swinburne University of Technology
National Sports Institute of Malaysia

Completed

The Potential of a Low Oxygen Environmental Chamber as an Aid to Exercise Training to Improve Metabolic Health

Healthy | Overweight | Physical Inactivity

Malaysia
Marinomed Biotech AG

Completed

Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis

Allergic Rhinitis | Allergic Conjunctivitis

Austria
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions (SIMBA)

Allergic Rhinitis

Germany
Carecubes, Inc.
University of Nebraska

Completed

Evaluating Patient Comfort and Environmental Conditions in the Carecube Negative Pressure Isolation Chamber.1

Infectious Diseases

United States
Ataturk University

Completed

The Efficacy of Oral Antiseptics Against COVID-19

COVID-19

Turkey
Alyatec

Completed

Evaluation of the Nasal and Conjunctival Response in Subjects Allergic to Birch Pollen in the ALYATEC Environmental Exposure Chamber

Allergic Rhinitis | Rhinoconjunctivitis | Allergy to Pollen

France
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers. (Mitey Nose)

Healthy Participants | Tobacco Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model (Kitty Nose)

Tobacco Smoking | Healthy Participants | E-cigarette Smokers

United States
Marinomed Biotech AG

Completed

Demonstration of a Decongestant Effect of "Coldamaris Akut" Compared to Saline Nasal Spray.

Allergic Rhinitis | Allergic Rhinoconjunctivitis

Austria
Marinomed Biotech AG

Completed

Demonstration of an Anti-allergic Effect in Subjects Treated With Callergin Nasal Spray in Comparison to Untreated Subjects and Subjects Treated With Vis Alpin® Alpensalz Nasal Spray, All Suffering From Grass Pollen Induced Rhinitis/Rhinoconjunctivitis

Allergic Rhinitis | Allergic Rhinoconjunctivitis

Austria
Windward Islands Research and Education Foundation
Grand Challenges Canada; St. George's University; GRENCASE

Completed

Community-Based Conscious Discipline Program in Grenada

Development, Child | Behavior, Child | Neurocognition, Child

Grenada
Alyatec

Completed

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Cat Allergic Subjects With Asthma

Allergy | Allergic Asthma | Allergy to Cats

France
Alyatec

Completed

Efficacy of Air Cleaners in Asthmatics Allergic to Cat in ALYATEC Environmental Exposure Chamber

Asthma | Allergy

France
Alyatec

Completed

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma

Allergy | Allergic Asthma | Allergy to House Dust

France
Allergy Therapeutics

Terminated

Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
Nestlé

Completed

Effect of a Specific Blend of Fibers and Probiotics on the Microbiome

Microbiota Perturbation by an Environmental Challenge

Switzerland
Marinomed Biotech AG

Completed

Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray

Allergic Rhinitis | Allergic Conjunctivitis | Hayfever

Austria
Bausch & Lomb Incorporated

Completed

Safety, Pharmacokinetics, and Efficacy of Bepotastine Besilate Nasal Product After Ragweed Pollen Exposure in an Environmental Chamber

Seasonal Allergic Rhinitis

United States
Johann Wolfgang Goethe University Hospital

Completed

Diagnostics and Quality of Life With EIA and EILO

Exercise Induced Asthma | Exercise Induced Pharyngeal Collapse

Germany
Aldeyra Therapeutics, Inc.

Completed

A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber

Conjunctivitis, Allergic

Canada
University of Maryland, Baltimore
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Challenge! Adolescent Obesity Prevention (Challenge)

Obesity | Overweight

United States
Farabi Eye Hospital

Unknown

Povidone-iodine 2% Eye Drop Versus Artificial Tear Drop for Treatment of Adenoviral Keratoconjunctivitis

Adenoviral Keratoconjunctivitis
Karolinska University Hospital
Experimental Asthma and Allergy Research Unit, Karolinska Institutet; Unit... and other collaborators

Terminated

Pemirolast in Allergen Challenge (PEMAG) (PEMAG)

Allergic Asthma

Sweden
Dynavax Technologies Corporation

Completed

An Evaluation of the Efficacy and Safety of TOLAMBA™ for Ragweed-Allergic Rhinitis in an Environmental Exposure Chamber

Rhinitis, Allergic, Seasonal

Canada
Queen's University
Biogenics Research Chamber, LLC

Completed

Comparability and Standardization of Controlled Allergen Challenge Facilities

Allergic Rhinitis

Canada, United States
Faes Farma, S.A.
Allied Research International

Completed

PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)

Seasonal Allergic Rhinitis | Hay Fever | Rhinoconjunctivitis

Canada
Red Maple Trials Inc.
Ottawa Allergy Research Corporation

Completed

Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects (NEC)

Allergic Rhinitis | Rhinoconjunctivitis | Exposure

Canada
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis

Atopic Dermatitis | Allergy Pollen

Germany

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