Search clinical trials for: Epileptic Syndromes

Total 17097 results

Neurona Therapeutics

Not yet recruiting

Effect of NRTX-1001, a Cellular Therapy Product, for the Treatment of Refractory Bilateral TLE

Epilepsy, Temporal Lobe
Takeda

Recruiting

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United Kingdom, Denmark
Takeda

Not yet recruiting

A Study on Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) in Children, Teenagers and Adults in Portugal (DRALEGA-PT)

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)
Second Affiliated Hospital, School of Medicine,...

Recruiting

Idiopathic Generalized Epilepsy Syndromes

Epilepsy | Epilepsy, Idiopathic Generalized

China
Przemyslaw Kunert
NaoX Technologies; Warsaw Medical University Clinical Center; Departments and...

Not yet recruiting

Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes

Epilepsy | Drug Resistant Epilepsy | Focal Epilepsy

Poland
UCB Biopharma SRL

Not yet recruiting

A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

Childhood Absence Epilepsy | Juvenile Absence Epilepsy
Johns Hopkins University

Not yet recruiting

Artificial Intelligence-based Video Analysis to Detect Infantile Spasms

Infantile Spasms

United States
Eysz, Inc.
University of Colorado, Denver; Wake Forest University Health Sciences; Children...

Recruiting

Assessing Comorbidities in Epilepsy Using Eye Movement Recordings (ACER)

Childhood Absence Epilepsy | Absence Seizures | Epilepsy Comorbidities

United States
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
University College, London
University of North Carolina, Chapel Hill; NYU Grossman School of Medicine

Recruiting

Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study (DRPLA NHBS)

Dentatorubral-Pallidoluysian Atrophy

United States, United Kingdom
Assistance Publique - Hôpitaux de Paris
OSO-AI

Recruiting

Characterization by Automated System on Infantile Spasmes (REASSESS)

Infantile Spasm

France
Al-Azhar University

Recruiting

Epileptic Syndromes in Infants and Early Childhood

Epileptic Syndromes

Egypt
All India Institute of Medical Sciences, New Delhi

Recruiting

Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation

West Syndrome

India
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Dravet Syndrome

Australia
National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
Eysz, Inc.
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Detecting Absence Seizures Using Hyperventilation and Eye Movement Recordings (DASHER)

Seizures | Absence Epilepsy | Epilepsy in Children | Absence Seizures | Absence Epilepsy, Childhood | Staring

United States
uniQure France SAS

Recruiting

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

Mesial Temporal Lobe Epilepsy

United States
University Hospital, Grenoble
Institut National de la Santé Et de la Recherche Médicale, France; Université...

Not yet recruiting

Innovative MRI to Localize the Epileptic Zone (EPI-CATCHER)

Epilepsy, Temporal Lobe
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score

Unconsciousness | Traumatic Brain Injury | Subarachnoid Hemorrhage | Coma | Infratentorial Neoplasms | Epilepsy, Temporal Lobe | Assessment, Self | Intensive Care Neurological Disorder | Arnold Chiari Malformation | Cerebrovascular Event | Postoperative Intracranial Hematoma | Postoperative Intracranial Haemorrhage and other conditions

Turkey
Takeda

Recruiting

A Study to Gather Information About Overall Occurrence and New Cases of Dravet and Lennox-Gastaut Syndromes in Children, Teenagers and Adults in Spain (DRALEGA)

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

Spain
Lady Hardinge Medical College

Recruiting

Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)

Epileptic Spasms, Failed Hormonal Therapy

India
Genovate-NaviFUS (Australia) Pty Ltd.
Genovate Biotechnology Co., Ltd.,; NaviFUS Corporation

Recruiting

Evaluation of the NaviFUS System in Drug Resistant Epilepsy

Drug Resistant Epilepsy | Epilepsy, Temporal Lobe

Australia
University Hospital, Angers

Recruiting

Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes (SURF)

Epilepsy in Children | Importance of Interictal Epileptiform Activity on Sleep EEG

France
University of California, Davis

Not yet recruiting

Sleep Architecture & Intrinsic Oscillatory and Network Connectivity in Cognition and Executive Dysfunction in TLE

Temporal Lobe Epilepsy
Cook Children's Health Care System
Encoded Therapeutics

Recruiting

GABA Biomarkers in Dravet Syndrome

Dravet Syndrome

United States
Sanguine Biosciences

Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Heart Diseases | Stroke | Lymphoma | Multiple Sclerosis | Kidney Diseases | Diabetes | Leukemia | Age-Related Macular Degeneration | Cancer | Arthritis | Schizophrenia | Thyroid Diseases | Parkinson Disease | Hepatitis | Vasculitis | Psoriasis | Asthma | Amyloidosis | Fibromyalgia | Graves Disease | Alzheimer Disease | Celiac Disease | Cirr... and other conditions

United States
Longboard Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Dravet Syndrome | Lennox-Gastaut Syndrome | Developmental and Epileptic Encephalopathy

United States, Australia
The University of Texas Health Science Center,...
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

PRIME: PReservIng Memory in Epilepsy

Mesial Temporal Lobe Epilepsy

United States
Assistance Publique Hopitaux De Marseille

Recruiting

Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy (REPREO)

Epilepsy | Temporal Lobe Epilepsy | Anomia

France
Esraa Mostafa Ahmed Abdel Aal

Not yet recruiting

Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure (seizure)

Localization-Related (Focal) (Partial) Idiopathic Epilepsy and Epileptic Syndromes With Seizures of Localized Onset | TRAIL: Tumor Necrosis Factor Related Apoptosis Inducing Ligand MCP-2 | MCP-2: Monocyte Chemo-attractant Protein-2
University Health Network, Toronto
Zogenix, Inc.

Not yet recruiting

Fenfluramine for Adult Dravet Patients

Dravet Syndrome | Dravet Syndrome, Intractable

Canada
LMU Klinikum
University of Pisa; German Federal Ministry of Education and Research; European...

Recruiting

Global Registry and Natural History Study for Mitochondrial Disorders

Mitochondrial Diseases | MDS | Mitochondrial Myopathies | MELAS Syndrome | MIDD | Kearns-Sayre Syndrome | MERRF Syndrome | Barth Syndrome | Leigh Syndrome | MNGIE | LHON | Pearson Syndrome | NARP Syndrome | Coenzyme Q10 Deficiency | SANDO | SCAE | MIRAS | CPEO

Austria, Germany, Italy
Biocodex

Recruiting

Retrospective Non-interventional Study of Stiripentol Use in Dravet Patients in the USA

Dravet Syndrome

United States
Jazz Pharmaceuticals
Evidilya S.r.l.

Not yet recruiting

Epidyolex® in Lennox Gastaut and Dravet Syndrome: an Observational Study in ITALY (EpiTALY)

Dravet Syndrome | Lennox Gastaut Syndrome

Italy
Hospices Civils de Lyon

Recruiting

Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome (AUTONOMIC)

Epilepsy | Dravet Syndrome

Belgium, France, Germany
Capsida Biotherapeutics, Inc.

Not yet recruiting

Natural History Study in Pediatric Patients With STXBP1 Encephalopathy With Epilepsy

STXBP1 Encephalopathy With Epilepsy
University College, London
King's College London; King's College Hospital NHS Trust; University of Oxford; Great Ormond Street Hospital for Children NHS Foundation Trust

Recruiting

Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot (CADET Pilot)

Epilepsy | Lennox-Gastaut Syndrome, Intractable

United Kingdom
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome (ENDEAVOR)

Dravet Syndrome

United States
Ann & Robert H Lurie Children's Hospital of Chicago
Patient-Centered Outcomes Research Institute; Johns Hopkins University; University... and other collaborators

Not yet recruiting

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

Lennox Gastaut Syndrome
Central Hospital, Nancy, France

Recruiting

Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients (CARTA)

Cognitive Decline | Epilepsy, Temporal Lobe

France
NeuroPace
National Institute of Neurological Disorders and Stroke (NINDS); University...

Recruiting

RNS System LGS Feasibility Study

Epilepsy | Seizures | Lennox Gastaut Syndrome | Lennox-Gastaut Syndrome, Intractable | Seizures, Generalized

United States
SK Life Science, Inc.

Recruiting

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

Seizures | Lennox Gastaut Syndrome

United States, Korea, Republic of, Taiwan, Colombia, Australia, Poland, Serbia, Mexico, Spain, Greece, Italy, Portugal, Germany, Argentina, Israel
ETH Zurich
Swiss Epilepsy Centre - Klinik Lengg

Recruiting

Self-modulation of the Sense of Agency by Means of Real-time Neurofeedback (NF-Agency)

Health, Subjective | Epilepsy, Temporal Lobe | Psychogenic Seizure

Switzerland
University of Southern California

Recruiting

Exercise for Brain Regeneration in Epilepsy

Temporal Lobe Epilepsy

United States
Takeda

Recruiting

A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

Lennox Gastaut Syndrome (LGS) | Dravet Syndrome (DS)

United States, China, Spain, France, Belgium, Australia, Brazil, Canada, Germany, Greece, Hungary, Italy, Japan, Latvia, Netherlands, Poland, Serbia, Mexico, Russian Federation, Ukraine
Neurona Therapeutics
California Institute for Regenerative Medicine (CIRM)

Recruiting

FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

United States
Assistance Publique - Hôpitaux de Paris
Orphelia Pharma

Not yet recruiting

Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents (EPIRARE)

Epilepsy | Dravet Syndrome | West Syndrome

France
Epygenix

Not yet recruiting

EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children With Lennox Gastaut Syndrome (LGS)

Lennox Gastaut Syndrome
Jazz Pharmaceuticals

Recruiting

Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Tuberous Sclerosis Complex | Dravet Syndrome | Lennox Gastaut Syndrome

United States

Search clinical trials for: Epileptic Syndromes

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