Search clinical trials for: Floxuridine (FUDR)

Total 68 results

Memorial Sloan Kettering Cancer Center
Wake Forest University

Completed

A Phase II Study of Continuous Hepatic Arterial Infusion With Floxuridine (FUDR) and Dexamethasone (DEX) in Patients With Unresectable Primary Hepatic Malignancy

Hepatic Cancer

United States
Duke University

Recruiting

Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer

Pancreatic Ductal Adenocarcinoma

United States
Sun Yat-sen University

Terminated

FUDR/Oxaliplatin HAI Plus Irinotecan vs. FOLFOXIRI Chemotherapy in Treating Initially Unresectable CRCLM

Metastatic Colorectal Cancer | Liver Metastases

China
The Netherlands Cancer Institute
Erasmus Medical Center

Recruiting

Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT) (PUMP-IT)

Colorectal Neoplasms

Netherlands
Spectrum Health Hospitals

Recruiting

Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases

Pancreatic Adenocarcinoma | Liver Metastases

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC)

Intrahepatic Cholangiocarcinoma | Cholangiocellular Carcinoma | Peripheral Cholangiocarcinoma | Cholangiolar Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Washington University School of Medicine; The Cleveland Clinic; Oregon Health... and other collaborators

Withdrawn

Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the Liver

Colorectal Adenocarcinoma Metastatic to the Liver

United States
Michael J Cavnar, MD

Terminated

Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Bile Duct Neoplasms

United States
Sun Yat-sen University

Terminated

Adjuvant Systemic Chemotherapy With or Without HAI-FUDR in Patients With Resected CRLM

Colorectal Cancer | Liver Metastases | HAI

China
Benaroya Research Institute
Virginia Mason Hospital/Medical Center

Recruiting

A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma

Colorectal Cancer | Cholangiocarcinoma

United States
NYU Langone Health
Food and Drug Administration (FDA)

Completed

Adjuvant Intraperitoneal Floxuridine Added to Chemoradiation for Fully Resected Advanced Stomach Cancer

Stomach Cancer | Gastric Cancer

United States
IRCCS San Raffaele

Unknown

Preoperative Hepatic Arterial Infusion Chemotherapy

Colorectal Liver Metastases

Italy
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma

Colorectal Cancer | Cholangiocarcinoma

United States
Sun Yat-sen University

Completed

A Study of Systemic Chemotherapy With CPT-11 Plus HAI (FUDR+L-OHP) in Patients With Initially Unresectable CRCLM

Liver Metastases | Colo-rectal Cancer

China
Xu jianmin
Ruijin Hospital; Zhejiang University; The Second Affiliated Hospital of Harbin...

Unknown

A Multi-center Randomized Controlled Trial of Intraportal Chemotherapy Combined With Adjuvant Chemotherapy (mFOLFOX6) for Stage II and III Colon Cancer

Colorectal Cancer | Metastasis

China
David Bartlett
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases

Colorectal Liver Metastases

United States
Fudan University
Second Affiliated Hospital, School of Medicine, Zhejiang University; Ruijin... and other collaborators

Unknown

Trial of Preoperative Hepatic and Regional Arterial Chemotherapy (PHRAC) to Prevent Postoperative Liver Metastasis of Colorectal Cancer (PHRAC)

Colorectal Neoplasms

China
Memorial Sloan Kettering Cancer Center
Washington University School of Medicine; University of Miami; The Cleveland... and other collaborators

Active, not recruiting

ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis (ICARuS)

Colorectal Cancer | Appendix Cancer

United States
NSABP Foundation Inc
National Cancer Institute (NCI)

Terminated

Oxaliplatin and Capecitabine With or Without an Hepatic Arterial Infusion With Floxuridine in Treating Patients Who Are Undergoing Surgery and/or Ablation for Liver Metastases Due to Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

United States
National Cancer Institute (NCI)

Completed

Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Stage IV Fallopian Tube Cancer AJCC v6 and v7 | Stage IV Ovarian Cancer AJCC v6 and v7 | Stage IV Primary Peritoneal Cancer AJCC v7

United States
NYU Langone Health

Terminated

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Gastric Cancer | Esophageal Cancer | Gastric Adenocarcinoma

United States
Washington University School of Medicine

Terminated

Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Liver Neoplasms | Cholangiocarcinoma

United States
City of Hope Medical Center

Completed

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
University of Miami

Completed

Combination Chemotherapy in Treating Patients With Previously Untreated Stage II or Stage III Esophageal Cancer That Can Be Removed By Surgery

Esophageal Cancer

United States
National Cancer Institute (NCI)

Recruiting

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma | Colorectal Adenocarcinoma | Colorectal Cancer With Hepatic Metastases

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery

Intrahepatic Cholangiocarcinoma

United States
University of Miami

Terminated

Combination Chemotherapy as First-Line Therapy in Treating Patients With Stage IV Gastric Cancer That Cannot Be Removed By Surgery

Gastric Cancer

United States
National Cancer Institute (NCI)
NSABP Foundation Inc

Completed

Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
Yuhong Li

Recruiting

A Study of Systemic Chemotherapy With/Without HAI in Patients With Initially Unresectable Colorectal Liver Metastasis

Metastatic Colorectal Cancer

China
Xiangya Hospital of Central South University

Completed

Hepatic Artery Infusion Pump for NPC Liver Metastases

Nasopharyngeal Carcinoma | Neoplasm Metastasis | Liver
OHSU Knight Cancer Institute
Oregon Health and Science University

Active, not recruiting

mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8 | Liver and Intrahepatic Bile Duct Carcinoma | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Intrahepatic Cholangiocarcinoma

United States
Ye Xu

Unknown

Alternating Systemic and Hepatic Artery Infusion Therapy As Adjuvant Treatment After Resection of Liver Metastases From Colorectal Cancer

Resected Liver Metastases From Colorectal Cancer

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Oslo University Hospital

Recruiting

HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT) (TOMCAT)

Intrahepatic Cholangiocarcinoma | Chemotherapy Effect

Norway
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
Oslo University Hospital

Recruiting

HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden. (EXCALIBUR1+2)

Colorectal Cancer | Chemotherapy Effect | Liver Metastases

Norway
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Colorectal Cancer | Metastatic Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by Surgery

Liver Cancer

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer

Rectal Cancer | Colon Cancer | Hepatic Metastases

United States
Luye Pharma Group Ltd.

Enrolling by invitation

Safety, Tolerability, Pharmacokinetics (PK), and Primary Clinical Efficacy of LY01616 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Memorial Sloan Kettering Cancer Center
Amgen

Active, not recruiting

Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer

Metastatic Colorectal Cancer

United States
Howard Aizenstein
National Institute of Mental Health (NIMH); Weill Cornell Institute of Geriatric...

Completed

Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO) (NEMO)

Major Depressive Disorder

United States
National Institutes of Health Clinical Center (CC)

Completed

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); University of Medicine and Dentistry of New...

Active, not recruiting

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

United States
Jazz Pharmaceuticals

Completed

Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer

Colorectal Neoplasms

United States, Canada
Memorial Sloan Kettering Cancer Center
Sanofi; Rutgers, The State University of New Jersey; University of Medicine and...

Completed

Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Intravenous Oxaliplatin Plus Irinotecan in Patients With Unresectable Hepatic Metastases From Colorectal Cancer

Rectal Cancer | Colon Cancer

United States
GlaxoSmithKline

Completed

A Study to Evaluate Efficacy and Safety of Daprodustat Compared to Darbepoetin Alfa in Japanese Hemodialysis (HD)-Dependent Subjects With Anemia Associated With Chronic Kidney Disease (CKD)

Anaemia

Japan
Memorial Sloan Kettering Cancer Center
Washington University School of Medicine; Ohio State University; University of...

Completed

Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Gemcitabine as Adjuvant Treatment After Resection of Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma | Peripheral Cholangiocarcinoma | Cholangiolar Carcinoma | Cholangiocellular Carcinoma) (ICC)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Colorectal Cancer | Metastatic Cancer

United States
University of Miami

Terminated

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Colorectal Cancer

United States

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