Search clinical trials for: GABA modulator

Total 22914 results

Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer (POMPPR)

Pain, Postoperative | Anxiety | Sleep Disturbance | Preoperative | Midazolam

China
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
Tongji Hospital

Not yet recruiting

Effect of Amobarbital Sodium Combined With Low-dose Propofol on Hemodynamics During Induction and Perioperative Adverse Reactions

Hemodynamics Instability | Amobarbital Sodium
Amany Ahmed Eissa

Recruiting

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.

Erector Spinae Plane Block | Bariatric Surgery | Super Obese Patients

Egypt
State University of New York - Upstate Medical...

Not yet recruiting

Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult

Altered Mental Status
Boehringer Ingelheim

Recruiting

A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood

Healthy

Belgium
Alexandria University

Not yet recruiting

Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting

Procedural Sedation
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Midazolam in the Blood When Both Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Martha Sajatovic

Recruiting

Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care

Epilepsy

United States
Jemincare

Not yet recruiting

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Solid Tumor, Adult
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States
Insel Gruppe AG, University Hospital Bern
University Hospital, Basel, Switzerland; University Hospital, Zürich; Stadtspital...

Not yet recruiting

Administration of Intranasal Midazolam for Anxiety in Palliative Care (AIM Care)

Anxiety | Acute Anxiety

Switzerland
Boehringer Ingelheim

Recruiting

A Study in Healthy People to Test How Well Different Doses of BI 3000202 Are Tolerated and How They Affect the Way the Body Handles Midazolam

Healthy

Belgium
Federico II University

Not yet recruiting

Focal Microvibration and Chronic Lumbosacral Radicular Pain

Pain, Chronic | Lumbosacral Radiculopathy | Radicular; Neuropathic
Eccogene

Recruiting

ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Type 2 Diabetes Mellitus

United States
The Cleveland Clinic

Recruiting

Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor (TRaNCE)

Essential Tremor

United States
University of Monastir

Not yet recruiting

Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo (Vertigo)

Vertigo, Peripheral
Pfizer

Recruiting

A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Yeungnam University Hospital

Not yet recruiting

Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (REST)

Remimazolam | Midazolam

Korea, Republic of
Peking University Third Hospital

Recruiting

Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients

Diabetes

China
Wenzhou Central Hospital

Not yet recruiting

A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia (ESAAEDI)

Estazolam-dependent Insomnia
Inonu University

Not yet recruiting

Dose Low Dose Ketamine in Casesarian

Postoperative Pain | Postpartum Depression

Turkey
Minneapolis Veterans Affairs Medical Center

Not yet recruiting

Ketamine Treatment for PTSD and MDD in TBI

Traumatic Brain Injury | Major Depressive Disorder | PTSD, Post Traumatic Stress Disorder

United States
Esraa Abdel Azez Soltan Mohamed Zayed

Not yet recruiting

Emergency Delirium in Pediatrics Undergoing Tonsillectomy and Adenoidectomy

Emergence Delirium
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

"Chou's Tiaoshen" Acupoints for Short-term Insomnia.

Short-term Insomnia

China
Aeovian Pharmaceuticals, Inc.

Recruiting

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Healthy Participants

Australia
Sichuan Provincial People's Hospital

Not yet recruiting

Effect of Remazolam on Anesthesia Recovery in Patients Undergoing Fundus Surgery

Postoperative Recovery | Remazolam Anesthesia
Siriraj Hospital

Recruiting

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Critical Illness | Respiratory Failure | Lung Injury | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication

Thailand
Eli Lilly and Company

Recruiting

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Healthy | Overweight | Obese

United States
Ain Shams University

Not yet recruiting

Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy

Anesthesia
Pfizer

Recruiting

A Study to Understand the Effect of Multiple Ascending Doses of PF-07293893 in Healthy Adult Participants

Healthy Participants

Belgium
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Healthy Subjects

China
The Royal Ottawa Mental Health Centre
The Royal's Institute of Mental Health Research

Recruiting

Characterizing Response to Antipsychotics in Schizophrenia

Schizophrenia | Schizoaffective Disorder

Canada
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, First-in-human Study of VX-828

Cystic Fibrosis

United States
Medical University of South Carolina

Not yet recruiting

Induction in the Dark

Anesthesia Induction

United States
Jinling Hospital, China

Recruiting

Comparison of Perioperative Conscious Sedation During Endovascular Thrombectomy in Acute Ischemic Stroke (PEACE)

Acute Ischemic Stroke

China
Icahn School of Medicine at Mount Sinai

Recruiting

Psychopharmacological Treatment of Emotional Distress

Psychological Distress | Suicide Crisis Syndrome

United States
Ruijin Hospital

Recruiting

Organ Protective Effect of Cetirizine In Patients With Severe Burns

Burns

China
Kasr El Aini Hospital

Recruiting

Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events

Tonsillectomy | Adenoidectomy | Drug-Related Side Effects and Adverse Reaction

Egypt
Eli Lilly and Company
Loxo Oncology, Inc.

Not yet recruiting

A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants

Healthy

United States
National University of Malaysia

Recruiting

Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.

Pancreatic Cancer | Cholangitis | Choledocholithiasis | Choledochal Cyst

Malaysia
Pfizer

Recruiting

A Study to Learn How Different Amounts of the Study Medicine Called PF-07976016 Are Tolerated and Act in The Body in Healthy Adults

Healthy

United States
Temple University
BioXcel Therapeutics Inc

Recruiting

Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar Disorder

Bipolar Disorder | Dexmedetomidine | Schizo Affective Disorder | Schizophrenia Agitation

United States
University Hospital of North Norway
University of Exeter

Not yet recruiting

Ketamine for Combined Depression and Alcohol Use Disorder (KeDA)

Depression | Alcohol Use Disorder
Beni-Suef University

Recruiting

Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy

Neuropathy in Cacer Patien

Egypt
University of North Carolina, Chapel Hill

Recruiting

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Stroke | Brain Ischemia | Brain Injuries, Traumatic | Heart Arrest | Intracranial Hemorrhages | Brain Hypoxia | Coma | Hypoxia-Ischemia, Brain | Persistent Vegetative State | Brain Injuries, Acute

United States
Assiut University

Not yet recruiting

Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia

Postoperative Pain
Stanford University

Not yet recruiting

Microbiome Sampling in GI Disease With a Focus on Small Intestinal Microbial Assessment

Healthy | Inflammatory Bowel Diseases | IBS - Irritable Bowel Syndrome

Search clinical trials for: GABA modulator

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