Search clinical trials for: GIP/GLP-1 dual receptor agonist

Total 67141 results

Royal North Shore Hospital

Not yet recruiting

Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity (TZP-T1D)

Type 1 Diabetes Mellitus | Overweight and Obesity
Eli Lilly and Company

Active, not recruiting

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both (SURPASS-PEDS)

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Type2 Diabetes | Metabolic Disease | T2DM (Type 2 Diabetes Mellitus) | T2D

United States, India, Australia, United Kingdom, Mexico, Brazil, Israel, France, Italy
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes (SURPASS-2)

Type 2 Diabetes

United States, Puerto Rico, Australia, United Kingdom, Mexico, Argentina, Brazil, Israel, Canada
University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin (SURPASS-5)

Type 2 Diabetes

United States, Puerto Rico, Spain, Japan, Germany, Czechia, Poland, Slovakia
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin (SURPASS-6)

Type 2 Diabetes

United States, Puerto Rico, Spain, Germany, Argentina, Brazil, Turkey, Hungary, Italy, Russian Federation, Slovakia, Belgium, Czechia, Greece, Mexico, Romania
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone (SURPASS-1)

Type 2 Diabetes Mellitus

United States, Japan, India, Puerto Rico, Mexico
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Delinieation of GIP's Effects During a Meal in Humans Using GIP Receptor Antagonisation (GA-4)

Glucose Metabolism Disorders

Denmark
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist (GA-3)

Glucose Metabolism Disorders

Denmark
Mikkel Christensen
University of Copenhagen

Completed

GIP and GLP-1 in Type 1 Diabetes

Hypoglycemia

Denmark
Uppsala University
Karolinska Institutet; University of Copenhagen

Completed

GIP and GLP-1 on Gastric Emptying, Appetite and Insulin-glucose (GIP-GLP-gas)

Physiology | Gastroenterology | Endocrinology

Sweden
Guangdong Raynovent Biotech Co., Ltd

Recruiting

The Safety, Tolerability and Pharmacokinetic Study of RAY1225

Healthy | Obese

China
Lund University

Completed

Effect of the DPP-4 Inhibitor Sitagliptin on Islet Function After Mixed Meal in Patients With Type 2 Diabetes

Type 2 Diabetes

Sweden
University of Bath
Arla Foods

Completed

The Dose Response of Calcium Co-ingested With Protein on GLP-1 Concentrations (PROCAL)

GLP-1 Concentration

United Kingdom
Lund University

Completed

Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers

Healthy Volunteers Recruited From the General Population

Sweden
Rigshospitalet, Denmark

Completed

Hyperglycemia and the Extra-pancreatic Effect of Incretins

Extra-pancreatic Incretin Effect | Glucose Effectiveness

Denmark
Herlev Hospital
University of Copenhagen; The Danish Medical Research Council; The Danish Diabetes...

Completed

GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia

Type 2 Diabetes Mellitus

Denmark
University Hospital, Gentofte, Copenhagen

Completed

GIP/GLP-1 Co-Activity in Subjects With Obesity: Lowering of Food Intake (GASOLIN)

Obesity | Type 2 Diabetes | Adiposity

Denmark
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Effects of Sucralose in Gut Intestinal Microbiota and Postprandial GLP-1

Gut Microbiota | GLP-1

Mexico
University of Copenhagen
Hvidovre University Hospital

Completed

Gut Hormones and Bone Remodeling in Humans (KS-2) (KS-2)

Healthy

Denmark
National Institute on Aging (NIA)

Completed

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Healthy Volunteers

United States
David D'Alessio, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Incretin Action in Physiology and Diabetes

Insulin Secretion

United States
Hvidovre University Hospital

Completed

Insulinotropic Effect of GLP-1 and GIP After Dexamethasone

Type 2 Diabetes

Denmark
University of Copenhagen
Hvidovre University Hospital

Recruiting

Gut Peptides and Bone Remodeling in Individuals With Spinal Cord Injury

Spinal Cord Injuries

Denmark
Hvidovre University Hospital

Completed

Incretin Hormone Antagonism After Bariatric Surgery (INCA-BAR)

Bariatric Surgery

Denmark
University Hospital, Gentofte, Copenhagen

Completed

Effect of GIP After a Meal in Patients With Type 2 Diabetes (GA-7)

Type2 Diabetes

Denmark
Seoul National University Hospital

Completed

The Effects of Premeal Consumption of Protein-enriched Bar on Blood Glucose Level and Secretion of Hormones

Diabetes Mellitus

Korea, Republic of
Adrian Vella

Completed

Dose-response Study of Exendin-9,39 on Glucose Metabolism

Pancreatic Effects of 9,39-Exendin and 9,36-GLP-1

United States
The Catholic University of Korea

Completed

Short-term Effect of Intensive Insulin Therapy on Incretin Secretion

Type 2 Diabetes

Korea, Republic of
University of Missouri-Columbia

Completed

Pre-dinner vs. Post-dinner Exercise on Glycemic Control

Type 2 Diabetes
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Bo Feldt-Rasmussen

Completed

Elimination of Incretin Hormones in Patients With Severe Kidney Failure

Uremia

Denmark
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of Gut Peptides on Bone Remodeling. KS-4-Diabetes-19

Type 2 Diabetes Mellitus

Denmark
University Hospital, Gentofte, Copenhagen
The Novo Nordisk Foundation Center for Basic Metabolic Research

Recruiting

The Effect of Glucose-dependent Insulinotropic Polypeptide on the Alpha Cell Response to Hypoglycaemia in Patients With Type 1 Diabetes (GIPHYPO)

Hypoglycemia | Type1diabetes | Type 1 Diabetes

Denmark
Glostrup University Hospital, Copenhagen
University of Copenhagen

Completed

Fat-induced Release of GLP-1 in Humans

Type 2 Diabetes
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of Gut Peptides on Bone Remodeling (KS-3)

Healthy

Denmark
Turku University Hospital
Lund University

Completed

Splanchnic Blood Redistribution After Incretin Hormone Infusion and Obesity Surgery (GIP-PET)

Obesity | Type 2 Diabetes

Finland
Hvidovre University Hospital

Completed

Effect of GLP-1 and GIP on Insulin Secretion in Type-1 Diabetes Mellitus

Type-1 Diabetes Mellitus

Denmark
Hvidovre University Hospital
University of Copenhagen

Completed

Effect of RYGB on Alpha- and Beta Cell Function and Sensitivity to Incretins in Patients With Type 2 Diabetes (BETASIN)

Obesity, Morbid | Type2 Diabetes

Denmark
Rigshospitalet, Denmark
Department of Cardiovascular and Renal Research, University of Southern Denmark

Completed

Acute Effects of GLP-1 on Renal Hemodynamics (GLP1RRBF)

The GLP-1-mediated Gut-kidney Axis

Denmark
St. Luke's-Roosevelt Hospital Center
National Institutes of Health (NIH)

Completed

Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery

Obesity | Gastric Bypass Surgery

United States
Hospital Universitari Son Dureta
Fundació Mateu Orfila

Completed

Stress Hyperglycemia. Potential Role of Incretin Analogs

Hyperglycemia | Critical Illness

Spain
Oxford Brookes University
Roquette Frères

Completed

Glycaemic Response, Insulinaemic Response, GLP-1 and GIP Testing of Food Product Lines

Healthy

United Kingdom
University of Aarhus
Aarhus University Hospital; Arla Food Ingrediens

Completed

Gastro-intestinal and Hormonal Responses to Systemic Inflammatory Disease

Endotoxemia | Motility Disorder | Catabolic State

Denmark
University Hospital, Gentofte, Copenhagen

Completed

Is Insulin Resistance and/or Glucose Intolerance Pathogenetic in the Development of a Reduced Incretin Effect

Insulin Resistance | Glucose Intolerance

Denmark
Glostrup University Hospital, Copenhagen
University of Copenhagen; European Foundation for the Study of Diabetes

Completed

Insulinotropic Effect of GIP and GLP-1 Before and After Reduced Glucose Tolerance

Insulin Resistance | Inactivity | Deteriorated Glucose Homeostasis

Denmark
Dr Adnan Agha

Recruiting

Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue

Liver Fat | Type 2 Diabetes | Non-Alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis

United Arab Emirates
Diabeteszentrum Bad Lauterberg im Harz

Completed

The Reduced Insulinotropic Effect of a Continuous Infusion Relative to a Bolus Injection of GIP

Type 2 Diabetes
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of a Liquid Meal and Gut Hormones (GIP and GLP-2) on Bone Remodeling in Participants With Hypoparathyroidism. (KS-4-HypoPT)

Hypoparathyroidism

Denmark
Zealand Pharma

Completed

A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Healthy

Germany

Search clinical trials for: GIP/GLP-1 dual receptor agonist

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Czech Republic

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations