Search clinical trials for: Gene polymorphism

Total 268952 results

Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Helwan University

Not yet recruiting

Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. (Palbociclib)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer
Mahidol University

Not yet recruiting

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

BMI | Metabolic Syndrome | Insulin Resistance | NAFLD | Genetic Polymorphism | Cardiovascular Disease (CVD) | MASLD | Daily Step Count
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
University of Virginia
American Heart Association

Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism

United States
Zunyi Medical College

Recruiting

CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

ACS - Acute Coronary Syndrome | CYP2C19 Polymorphism

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors (NETTUNO)

Postoperative Complications | Surgical Procedure, Unspecified | Hyperlactatemia | Abdomen Disease

Italy
Novosibirsk Scientific Research Institute for Circulatory...

Recruiting

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting

Russian Federation
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
October 6 University
University of Florida; Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients

Heart Failure | Genetic Polymorphisms

United States
Marmara University

Not yet recruiting

Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization

Molar-Incisor Hypomineralization
The Republican Research and Practical Center for...
Belarusian State Medical University

Recruiting

To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers

Sepsis

Belarus
LI YAN

Not yet recruiting

Study on the Association of GSTP1 and Other Gene Polymorphisms With Platinum-induced Myelosuppression

Non-small Cell Lung Cancer
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina
Affiliated Hospital of Nantong University

Not yet recruiting

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Depression | Polymerase Chain Reaction | Polymorphism, Genetic | CYP1A2 Polymorphism | Plasma Concentration | CYP2C9 Polymorphism
Lebanese University
Haykel Hospital

Recruiting

Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms (CAT_PB)

Cardiovascular Diseases | Immune System Diseases | Cancer | Breast Cancer | Hepatocellular Carcinoma | Lung Cancer | Chemotherapy | Solid Tumor | Prostate Cancer | Thromboembolism | Colon Cancer | Immunotherapy | Inflammatory Diseases

Lebanon
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-Small Cell Lung Cancer

United States
Sohag University

Recruiting

Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases in Sohag Hospital University.

Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases

Egypt
Sohag University

Recruiting

SIRT1(rs7069102 ) Gene Polymorphism in Chronic Obstructive Pulmonary Disease at Egyptian Patients

Genotyping of SIRT1in Chronic Obstructive Pulmonary Disease

Egypt
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Alectinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-small Cell Lung Cancer

United States
Mazandaran University of Medical Sciences

Recruiting

Baricitinib Versus Azathioprine in Patients With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

Iran, Islamic Republic of
St. Antonius Hospital

Recruiting

POPular GUILTY PILOT: Genotype-guided Clopidogrel Monotherapy (POPular GUILTY)

Acute Coronary Syndrome | CYP2C19 Polymorphism

Netherlands
Yi Han
Qianfoshan Hospital

Recruiting

Study on the Correlation Between NAT2(N-acetyltransferase2) Gene Polymorphism and CrCl(Creatine Clreance) and the Efficacy and Safety of Levosimendan in Patients With Severe Heart Failure

Heart Failure | Efficacy | Safety | Levosimendan

China
Sohag University

Recruiting

Brain-derived Neurotrophic Factor (BDNF) Single Nucleotide Gene Polymorphism and Nerve Growth Factor as Risk Factors That Increase Severity of Allergic Rhinitis

Allergic Rhinitis

Egypt
The Republican Research and Practical Center for...
Belarusian State Medical University

Recruiting

Algorithm for Predicting the Unfavorable Course of Sepsis in Children

Sepsis

Belarus
Hospital Mutua de Terrassa

Recruiting

Mesenteric Bacterial Translocation in Evolved Crohn's Disease (MESENCROHN)

Crohn Disease

Spain
Kaohsiung Medical University Chung-Ho Memorial...
Ministry of Science and Technology, Taiwan

Recruiting

Effect of Gene Polymorphism on Cognitive Function

Cognitive Function | Polymorphosis

Taiwan
Ain Shams University

Recruiting

Effect of Renin Angiotensin Aldosterone System Genetic Polymorphism on the Pharmacological Effect of Mineralocorticoid Receptor Antagonists in Patients With Myocardial Infarction

Myocardial Infarction

Egypt
Sohag University

Recruiting

Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata

Alopecia Areata

Egypt
China Medical University Hospital

Recruiting

The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis

Allergic Conjunctivitis

Taiwan
IRCCS Burlo Garofolo

Recruiting

Genetic Polymorphisms in Drug Induced Neuropathy in Children With ALL

Acute Lymphocytic Leukemia

Italy
Hacettepe University

Recruiting

Weight Loss and CLOCK 3111T/C Polymorphism

Obesity | Polymorphism, Restriction Fragment Length

Turkey
Ain Shams University
Misr International University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non-small Cell Lung Cancer Patients

Non Small Cell Lung Cancer | Cardiotoxicity | Nephropathy

Egypt
Ain Shams University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Doxorubicin Among Egyptian Breast Cancer Patients

Breast Cancer

Egypt
Aristotle University Of Thessaloniki

Not yet recruiting

Peri-implantitis and MMP-8

Peri-Implantitis
Bangabandhu Sheikh Mujib Medical University, Dhaka...
Department of Genetic Engineering and Biotechnology, Dhaka University

Recruiting

Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS

Polycystic Ovary Syndrome | Metformin

Bangladesh
Sohag University

Not yet recruiting

Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development

Cataract

Egypt
Universiti Putra Malaysia
Ministry of Higher Education Malaysia

Recruiting

Vitamin D Deficiency With Selected Vitamin D Receptor Gene Polymorphism in Gestational Hypertension

Vitamin D Deficiency | Hypertensive Disorder of Pregnancy

Malaysia
Poznan University of Life Sciences

Recruiting

Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance

Skeletal Muscle Performance | Gene Polymorphisms

Poland
Sohag University

Recruiting

Expression of IRAK1 Gene rs1059703-related Single- Nucleotide Polymorphisms in Egyptian Patient With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)

Egypt
Sohag University

Not yet recruiting

" Effect of Single-nucleotide Polymorphism of CD40 Gene rs1883832 C/T on the Risk of Immune Thrombocytopenic Purpura "

Immune Thrombocytopenic Purpura

Egypt
Selcuk University
TC Erciyes University; Dokuz Eylul University; Ankara University; Selcuk University...

Not yet recruiting

Genome-Wide Association Study With the Aim of Implantable Cardioverter Defibrillator Implantation Genophenotypic Risk Stratification (ICDGPSS)

Sudden Cardiac Death | Arrythmia | ICD

Turkey
Sohag University

Not yet recruiting

Molecular Characterization of Blastocystis Isolates From Human by Restriction Fragment Length Polymorphism (RFLP) Analysis

Blastocystis Infections
Assiut University

Not yet recruiting

Relation of IL23R and IL17A Gene Polymorphisms Plus Serum Levels of IL23 and IL17A to Rheumatoid Arthritis Susceptibility and Activity

Rheumatoid Arthritis
Second Affiliated Hospital, School of Medicine,...

Recruiting

Association Between ALDH2 Gene Polymorphism and Atrial Fibrillation (AAAF)

Atrial Fibrillation

China

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