Search clinical trials for: Gene variants

Total 268806 results

Alnylam Pharmaceuticals

Recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
University Hospital, Lille
France Alzheimer

Not yet recruiting

Social & Affective Cognition in Alzheimer's Disease & Associated Disorders (SOCIALIZE)

Alzheimer's Disease | Frontotemporal Degeneration (Semantic & Behavioral Variants)
University Hospital Tuebingen

Recruiting

Non-Invasive Plasma Treatment for Cervical Infections: Targeting High- and Low-Risk HPV Variants

Cervical Cancer | HPV Infection

Germany
Medanta, The Medicity, India

Recruiting

Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes

Type2diabetes

India
Nantes University Hospital
AXA Assurances VIE Mutuelle

Not yet recruiting

Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome (BIOMINRISK)

Sudden Infant Death | Sudden Unexplained Infant Death

France
IRCCS San Raffaele

Recruiting

Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children

Pediatric Brain Tumor

Italy
University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Oscar Gerardo Arrieta Rodríguez

Recruiting

Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

Lung Adenocarcinoma

Mexico
Hospital do Rim e Hipertensão

Recruiting

Evaluation of APOL1 Gene Variants in Kidney Donors and Their Impact on Long-term Renal Function in Donors and Recipients

Kidney Diseases | Transplant Failure

Brazil
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Centre National...

Recruiting

Building of a Diagnostic/Prognostic Database for Human ERG Variant Effects (CarDiag)

Long QT Syndrome

France
Central Hospital, Nancy, France

Recruiting

Olfactory Cleft Stenosis and Obstruction on Paranasal Sinus CT Scan in Pre Septo Rhinoplasty Patients Without Respiratory Mucosa Pathology : Normal Variants or Pathologic Findings ?

Olfactory Impairment

France
Mario Negri Institute for Pharmacological Research

Recruiting

New Analytic Tools for aHUS and C3G Diagnosis (COMPRare)

Healthy | Hemolytic-Uremic Syndrome | Membranoproliferative Glomerulonephritis

Italy
University Hospital, Montpellier

Recruiting

Search for Structural Variants in Patients With DSD and Inconclusive Molecular Diagnosis (GENEXPLOR)

Disorder of Sex Development, 46,XY

France
Institut Pasteur
Biogroup Laboratoire de biologie médicale

Recruiting

Understanding the Determinants of Mucosal Immunity and Optimizing the Diagnosis of Infection With SARS-CoV-2 Variants (COVARIANT)

COVID-19

France
Hospital Universitari Vall d'Hebron Research Institute
Hospital Universitario La Paz

Not yet recruiting

Identification and Characterization of Genetic Variants in Hereditary Angioedema (GENOMAEH_01)

Hereditary Angioedema With C1 Esterase Inhibitor Deficiency

Spain
University Hospital, Basel, Switzerland

Recruiting

Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases (NEUTROSKIN)

Inflammatory Dermatoses | Neutrophil-mediated Inflammatory Dermatoses

Switzerland
Rigshospitalet, Denmark

Not yet recruiting

Follow-up Study on Female Carriers With DMD Gene Variants

Muscular Dystrophy | Duchenne Muscular Dystrophy | Becker Muscular Dystrophy

Denmark
University Hospital Muenster

Recruiting

Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.

Sepsis | Pre-Eclampsia | Adiposity | Microscopic Polyangiitis | Granulomatosis With Polyangiitis | SIRS | Procalcitonin

Germany
St. Louis University
Mid-America Transplant

Recruiting

APOL1 Genetic Testing in African Americans

Chronic Kidney Diseases | Genetic Predisposition | Nephropathy

United States
Fudan University
Amoy Diagnostics Co., LTD

Recruiting

Assessment of Prognosis Using Peripheral Blood Circulating Tumor DNA in Patients With Cervical Cancer

Locally Advanced Cervical Cancer

China
Jaeb Center for Health Research
Foundation Fighting Blindness

Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants (Uni-Rare)

Retinitis Pigmentosa | Inherited Retinal Degeneration

United States, United Kingdom, France, Finland, Israel, Netherlands, Switzerland, Australia, Canada, Brazil, Mexico
Hospital Garcia de Orta
Instituto de Medicina Molecular João Lobo Antunes

Recruiting

Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants (SepticHeartG)

Septic Shock | Cardiomyopathies | Diastolic Dysfunction

Portugal
Fondation FondaMental

Recruiting

Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression (GENI)

Psychiatric Disorder

France
GrowBaby Life Project
Metagenics, Inc.; OmegaQuant, LLC

Not yet recruiting

Select Nutrient and Gene Variant Analysis in a Targeted Diet and Lifestyle Intervention Reduces Preterm Birth (SNGLI-PTB)

Premature Birth | Pre-Eclampsia | Small for Gestational Age Infant

United States
Istanbul University

Not yet recruiting

The Analysis of Gene Variants Related to POCD in Elderly Patients

Cognitive Dysfunction
University of Maryland, Baltimore

Recruiting

Comparing Direct vs Indirect Methods for Cascade Screening

Familial Hypercholesterolemia | Long QT Syndrome | Genetic Testing | Ethics

United States
Ospedale Policlinico San Martino

Recruiting

Investigation of Copy Number Variations and Genetic Variants in POI (POI)

Primary Ovarian Insufficiency

Italy
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; Institut...

Not yet recruiting

Variants of SARS-CoV-2 Causing COVID-19 in Africa (South-Spike)

COVID-19

Burkina Faso, Chad, Congo, Côte D'Ivoire, Gabon, Mali
GlaxoSmithKline

Recruiting

Study to Monitor the Occurrence of Viral Variants in Patients With Compromised Immune Systems Being Treated for COVID-19 (LUNAR)

COVID-19

United Kingdom
Assiut University

Not yet recruiting

Computed Tomography Anatomy of the Paranasal Sinuses and Anatomical Variants of Clinical Relevants in Egyptian Adults .

Sinusitis
Bionano Genomics
Columbia University; University of Iowa; Medical College of Wisconsin; Augusta... and other collaborators

Recruiting

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Intellectual Disability | Autism Spectrum Disorder | Fragile X Syndrome | Developmental Disability | Congenital Anomaly | Facioscapulohumeral Muscular Dystrophy 1

United States
RWTH Aachen University
B. Braun-Stiftung

Not yet recruiting

Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Polypharmacy | Pharmacogenomic Testing
Xinhua Hospital, Shanghai Jiao Tong University...

Not yet recruiting

Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 Variants

Alport Syndrome

China
Rigshospitalet, Denmark

Recruiting

MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants (ANO5 MRI)

Limb Girdle Muscular Dystrophy

Denmark
University Hospital, Montpellier
Hôpital Cochin; Hôpital Necker-Enfants Malades; Foch Hospital, Suresnes, FRANCE

Recruiting

Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies (ONB-CFTR)

Cystic Fibrosis | CFTR Gene Mutation

France
Rhythm Pharmaceuticals, Inc.

Recruiting

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Obesity | Genetic Obesity

United States, Spain, Germany, Netherlands, United Kingdom, Greece, Puerto Rico, Canada, France, Israel
Stanford University

Recruiting

CYP2C19 Variants and Limonene Metabolism

CYP2C19 Genetic Variants

United States
The Belgian Society of Medical Oncology
Illumina, Inc.; OncoDNA; PierianDx

Recruiting

A Study to Examine the Clinical Value of Comprehensive Genomic Profiling Performed by Belgian NGS Laboratories: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Centre (BALLETT)

Solid Tumor | Metastatic Cancer

Belgium
Arcturus Therapeutics, Inc.

Recruiting

A Trial Evaluating the Safety and Immunogenicity of 3 COVID-19 SARS-CoV-2 RNA Vaccines in Healthy Adults

COVID-19 | Corona Virus Infection | SARS-CoV-2 Infection

United States, Singapore
Bayer

Recruiting

Prophylaxis Regimen for Hemophilia A Patients (PREDICT)

Hemophilia A | Prophylaxis of Bleeding

United States
Parkinson's Foundation
Indiana University; The Parkinson Study Group; Fulgent Genetics

Recruiting

Parkinson's Foundation PD GENEration Genetic Registry

Parkinson's Disease

United States, Canada
Second Affiliated Hospital, School of Medicine,...

Recruiting

Multicenter Study on the Pathogenic Germline Gene Variants of Colorectal Polyposis in China

Colorectal Polyposis

China
Nanfang Hospital of Southern Medical University
303rd Hospital of the People's Liberation Army; Liuzhou Municipal Maternity... and other collaborators

Recruiting

Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

Beta Thalassemia

China
Assistance Publique Hopitaux De Marseille

Recruiting

PLIN1 Variants in Precocious ACS (SCAPLIN)

Acute Coronary Syndrome

France
Columbia University
National Institute on Aging (NIA)

Recruiting

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

Alzheimer Disease

United States
National Cancer Institute (NCI)

Recruiting

Precision-Based Genomics in Prostate Cancer

Prostate Cancer

United States, Spain
James M Noble, MD, MS, CPH, FAAN
National Institute on Aging (NIA)

Recruiting

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease (ADVISe)

Alzheimer Disease

United States
University Hospitals, Leicester

Recruiting

The BRAVE Study- The Identification of Genetic Variants Associated With Bicuspid Aortic Valve Using a Combination of Case-control and Family-based Approaches. (BRAVE)

Cardiovascular Diseases

United Kingdom
British Columbia Cancer Agency
Hoffmann-La Roche

Recruiting

Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity (CAPTIV-8)

Sarcoma | Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Lung Cancer | Skin Cancer | Gastrointestinal Cancer | Unknown Primary Tumors | Genitourinary Cancer

Canada
Institut National de la Santé Et de la Recherche...
France Alzheimer

Not yet recruiting

MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY (PET-AL)

Alzheimer Disease, Early Onset | Posterior Cortical Atrophy

France

Search clinical trials for: Gene variants

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