Search clinical trials for: General Safety

Total 273691 results

Boston Children's Hospital

Not yet recruiting

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE
SpliSense Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Beijing Tiantan Hospital

Not yet recruiting

Efficacy and Safety of Chinese Herbal Formula HuoXue LiShui for Chronic Subdural Hematoma (CHARM)

Chronic Subdural Hematoma

China
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM

Gastric Cancer, Metastatic
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients

Dry Eye | Dry Eye Syndromes

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

Registry Study to Determine the Effectiveness and Safety of Weight Loss With Enavogliflozin in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Aldeyra Therapeutics, Inc.

Recruiting

A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

United States
Ewha Womans University Seoul Hospital

Not yet recruiting

Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.

Stroke | Atherosclerosis
Enyo Pharma

Not yet recruiting

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1) (ALPESTRIA-1)

Alport Syndrome

Spain, United States, France, Germany
AstraZeneca

Recruiting

MultIceNtre Non-intERVentional Study for Efficacy,Safety Evaluation of BREZTRI in Pts With COPD in RussiA (MINERVA)

Chronic Obstructive Pulmonary Disease

Russian Federation
Indiana University
Dreamland Baby Co.

Recruiting

Assessment of the Safety and Efficacy of Weighted Wearable Blankets in Healthy Infants During Sleep

Sleep

United States
Istituto Clinico Humanitas

Not yet recruiting

Efficacy and Safety of Oral Administration of Postibiotic by FOS Fermentation From Lactobacillus Paracasei in the Treatment of Irritable Bowel Syndrome. (prePO23)

IBS - Irritable Bowel Syndrome

Italy
Haisco Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of HSK16149 Capsule in the Treatment of Moderate and Severe Central Neuropathic Pain in China

Central Neuropathic Pain
GeneCradle Inc

Recruiting

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Spinal Muscular Atrophy Type 3

China
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
University of Oxford
Oxford Brookes University; Oxford University Hospitals NHS Trust; Scholar Rock... and other collaborators

Not yet recruiting

Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA) (ACE SMA) (ACE SMA)

Spinal Muscular Atrophy

United Kingdom
Top Health S.A.P.I DE C.V.
CLINICAL RESEARCH PS MEXICO

Not yet recruiting

Study to Evaluate the Effectivity and Safety of BIOSCAFF®H Compared to DuraGen®, in Patients Undergoing Dural Repair

Cerebrospinal Fluid Leakage
89bio, Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Mannkind Corporation

Not yet recruiting

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension (ICoN-1)

Mycobacterium Infections, Nontuberculous | MAC Lung Disease | Treatment Refractory MAC Lung Disease

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma

Chloasma

China
Anhui Provincial Hospital

Not yet recruiting

A Study on the Safety and Preliminary Efficacy of NK042 in the Treatment of Malignant Ascites

Gynecologic Cancer

China
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
NMD Pharma A/S

Not yet recruiting

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis (SYNAPSE-MG)

Myasthenia Gravis | Myasthenia Gravis, MuSK
University of Florida
Cord for Life, Inc.

Recruiting

Open Label Dose Ranging Study Assessing the Safety of Cord Blood Product in Sacroiliac Joint Syndrome (SIJ) (SIJ)

Pain, Back | Sacroiliac; Backache

United States
Tianjin Medical University Cancer Institute and...

Recruiting

The Safety and Effectiveness of NEPA in Preventing Postoperative Nausea and Vomiting After General Anesthesia Gastrointestinal Cancer Surgery: A Single-Center Retrospective Study

General Anesthesia Gastrointestinal Cancer Surgery

China
Xeno Biosciences

Not yet recruiting

A Phase 1b Study to Evaluate the Safety of XEN-101

Obesity
University of Florence
Azienda Ospedaliera Città della Salute e della Scienza di Torino; University... and other collaborators

Recruiting

Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients (STAR)

Migraine | Chronic Migraine | Migraine Without Aura | Migraine With Aura

Italy
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Malaria Research and Training...

Not yet recruiting

Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali

Malaria,Falciparum
Orthofix s.r.l.

Not yet recruiting

Retrospective Study on Clinical Performance and Safety Profile of Agile Nail (Agile)

Fractures, Bone | Deformity; Bone | Impending Fracture

United Kingdom
Children's University Hospital Cologne, Germany
University of Cologne; University of Geneva, Switzerland; The Clinical Trials...

Not yet recruiting

Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders (ZINCGNAO1)

Epilepsy | Dystonia | Development Delay | GNAO1 | Developmental and Epileptic Encephalopathy 17 | Neurodevelopmental Disorder With Involuntary Movements | Choreoathetosis
Serum Institute of India Pvt. Ltd.

Recruiting

Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV

Hepatitis B Immunization | Diptheria Immunization | Tetanus Immunization | Pertussis Immunization | Haemophilus Influenzae Type B Immunization | Polio Immunization

Bangladesh, India
Charles University, Czech Republic

Not yet recruiting

Efficiency and Safety of the Prolonged Use of Heat and Moisture Exchangers in ICU (FILTRex)

VAP - Ventilator Associated Pneumonia
Suzhou Kerui Medical Technology Co., Ltd
Suzhou Mingshi Optical Technology Co., Ltd

Recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression

Myopia

China
SamA Pharmaceutical Co., Ltd

Recruiting

The Efficacy and Safety of Atock Dry Syrup With Acute Bronchitis Patients

Acute Bronchitis

Korea, Republic of
MoonLake Immunotherapeutics AG

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa
Medinol Ltd.

Not yet recruiting

First In Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients With Superficial Femoral Artery Disease and/or Proximal Popliteal Artery Disease (CHAMPIONSHIP)

Popliteal Artery Stenosis | Superficial Femoral Artery Stenosis
General Hospital of Shenyang Military Region

Not yet recruiting

Efficacy and Safety of Local Glucocorticoids for the Treatment of Radiation-Induced Intestinal Injury

Radiation-Induced Intestinal Injury

China
MoonLake Immunotherapeutics AG

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa
Celgene

Not yet recruiting

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

United States
University Hospital, Basel, Switzerland

Not yet recruiting

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors (ISCA-CHECK)

Advanced Solid Tumor

Switzerland
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Beijing Chest Hospital
The First Affiliated Hospital with Nanjing Medical University; Anhui Chest... and other collaborators

Recruiting

Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis

Tuberculosis | Treatment | Adjuvant

China
Tianjin Eye Hospital

Not yet recruiting

To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia

Myopia, Progressive

China
Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.

Not yet recruiting

Efficacy and Safety of Clascoterone Cream 1% in Facial Acne Vulgaris

Acne Vulgaris
Istanbul Demiroglu Bilim University

Not yet recruiting

Assessing the Impact of Monitor Maintenance Package Utilization

Patient Safety | Alarm Fatigue

Turkey
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

Alzheimer's Disease

Korea, Republic of, France

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