Search clinical trials for: Glutamine metabolism

Total 27524 results

Diamyd Medical AB

Recruiting

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes (DIAGNODE-3)

Type 1 Diabetes Mellitus

Czechia, Spain, United States, Hungary, Netherlands, Estonia, Germany, Poland, Sweden
University Hospital, Rouen

Not yet recruiting

Effects of Oral Glutamine Supplementation on Insulin Resistance and Functional Intestinal Disorders in Obese Patients. (OBEGLUT)

Obesity | Insulin Resistance

France
University of Wisconsin, Madison

Recruiting

In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

Chronic Lymphocytic Leukemia

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); Howard Hughes Medical Institute

Recruiting

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

Kidney Cancer | Renal Cell Carcinoma | Urothelial Carcinoma | Hereditary Leiomyomatosis and Renal Cell Cancer | Metastatic Urothelial Carcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | HLRCC | Clear Cell Carcinoma | Metastatic Kidney Cancer | Fumarate Hydratase Deficiency | Succinate...

United States
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Targeting Glutamine Metabolism to Prevent Diabetic Cardiovascular Complications (GLUTADIAB)

Diabetic | Cardiovascular Complications | Glutamine

France
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Plasma Cell Myeloma

United States
Linkoeping University
Diamyd Medical AB

Completed

Evaluation of a Booster Administration of GAD-alum (Diamyd®) in Individuals With Type 1 Diabetes

Diabetes Mellitus, Type 1

Sweden
Hospital Universitario 12 de Octubre

Active, not recruiting

Clinical Long Term Evaluation of Glutamine Supplement in MELAS Syndrome

MELAS Syndrome

Spain
Nemours Children's Clinic

Completed

Exercise Snacks and Glutamine to Improve Glucose Control in Adolescents With Type 1 Diabetes

Glucose Metabolism Disorders | Metabolic Diseases | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United States
Calithera Biosciences, Inc

Completed

CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma (CANTATA)

Metastatic Renal Cell Carcinoma | Advanced Renal Cell Carcinoma

United States, United Kingdom, Australia, France, Italy, Germany, Spain, New Zealand
Calithera Biosciences, Inc

Completed

Study of CB-839 in Combination w/ Paclitaxel in Participants of African Ancestry and Non-African Ancestry With Advanced Triple Negative Breast Cancer (TNBC)

Triple Negative Breast Cancer | TNBC - Triple-Negative Breast Cancer

United States
Calithera Biosciences, Inc

Completed

CB-839 With Everolimus vs. Placebo With Everolimus in Participants With Renal Cell Carcinoma (RCC) (ENTRATA)

Clear Cell Renal Cell Carcinoma

United States
Calithera Biosciences, Inc

Completed

Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

Renal Cell Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Solid Tumors | Triple-Negative Breast Cancer | Fumarate Hydratase (FH)-Deficient Tumors | Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST) | Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal... and other conditions

United States
Norwegian University of Science and Technology
Karolinska Institutet; Linkoeping University; St. Olavs Hospital; Diamyd Medical...

Completed

Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes (GADinLADA)

Latent Autoimmune Diabetes in Adults

Norway, Sweden
Jesús González de la Aleja Tejera

Completed

Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

MELAS Syndrome

Spain
Kaleido Biosciences

Terminated

UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder (UNLOCKED)

Urea Cycle Disorder

Belgium, United States, Spain, United Kingdom, Germany, Switzerland, Turkey
Nemours Children's Clinic
Thrasher Research Fund

Completed

Glutamine and Insulin Sensitivity in Type I Diabetes

Type I Diabetes Mellitus

United States
Columbia University

Completed

Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure (GLUTFISH-HF)

Heart Failure

United States
Centre Hospitalier Universitaire de Besancon

Unknown

Citrullinemia for the Prediction of Enteral Nutrition Tolerance Among Critically Ill Patients (PREDICT)

Biomarkers | Enteral Nutrition | Intensive Care Unit
Hawaii Pacific Health

Unknown

The Effect of Pharmaceutical Grade L-glutamine (Endari) on Glycemic Control in Patients With Diabetes Mellitus Type II

Diabetes Mellitus, Type 2
Massachusetts General Hospital
National Institutes of Health (NIH)

Withdrawn

Study of Glutamate and Glutamine Metabolism in Burn Patients Receiving Enteral or Parenteral Nutrition

Burns

United States
Massachusetts General Hospital
National Institutes of Health (NIH)

Withdrawn

Proline Metabolism in Severely Burned Patients: Effect of Modulated Parenteral Feeding

Burns

United States
Massachusetts General Hospital
National Institutes of Health (NIH)

Withdrawn

Glutamine Enriched Total Parenteral Feeding and Proline Metabolism in Severely Burned Patients

Burns

United States
Massachusetts General Hospital

Withdrawn

Effect of Glutamine Supplemented Nutrition Support on Protein and Glutamine Metabolism in Burns

Burns

United States
Boston Medical Center

Completed

Novel Type 2 Diabetes Mellitus Preventive Therapies

Diabetes

United States
Nicola Longo
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Anaplerotic Therapy in Propionic Acidemia

Propionic Acidemia

United States
Technical University of Munich
Gilead Sciences; MUC Research GmbH

Completed

Changes in Insulin Resistance in Healthy Volunteers on STRIBILD® Medication

Insulin Resistance

Germany
University of Zurich
Swiss National Science Foundation; University Hospital, Zürich; Fresenius Kabi

Completed

Optimized Therapy in Severe Traumatic Brain Injured Patients

Traumatic Brain Injury | Coma

Switzerland
University Hospital, Rouen

Completed

Glutamine and Intestinal Protein Metabolism

Healthy Volunteers

France
Medical Center Alkmaar

Unknown

Dipeptide Alanyl Glutamine and Postoperative Insulin Resistance in Colon Carcinoma Patients (AIRCo)

Colon Carcinoma

Netherlands
Massachusetts General Hospital
National Institutes of Health (NIH)

Unknown

Study of Arginine Metabolism and Nitric Oxide Formation in Relation to Glutamine Supply in Severely Burned Patients

Burns

United States
Rigshospitalet, Denmark

Completed

The Effect of Glutamine on Systemic Inflammation During Human Experimental Endotoxemia

Sepsis | Systemic Inflammation

Denmark
National Center for Research Resources (NCRR)
Baylor College of Medicine

Unknown

Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion

Hyperglycemia | Infant, Low Birth Weight

United States
Mansoura University

Recruiting

Prevalence Of Significant Endoscopic and Histopathologic Findings in Patients Presenting With Unexplained Iron Deficiency Anemia

Gastrointestinal Diseases

Egypt
University Hospital, Bordeaux

Not yet recruiting

Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma (GBrecurr)

Relapsed Cancer | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

France
Hospices Civils de Lyon

Not yet recruiting

Circadian Variation of Urinary Copper Excretion in Wilson Disease Patients (VARCUWIC)

Wilson Disease

France
McGill University Health Centre/Research Institute...

Not yet recruiting

Indigenous Youth and Young Adults With Diabetes Peer Mentorship Program

Diabetes Mellitus | Distress, Emotional
Tanta University

Recruiting

Nephroprotective Effect of Nicorandil in Type 2 Diabetes Mellitus

Type2 Diabetes Mellitus

Egypt
Central South University

Not yet recruiting

Investigating the Insulin Resistance in Individuals With Type 2 Diabetes

Type 2 Diabetes

China
Malmö University

Not yet recruiting

Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet Among Persons With Diabetes

Diabetes Mellitus | Skin and Connective Tissue Diseases
Tandem Diabetes Care, Inc.

Recruiting

Tandem Freedom - Feasibility Trial 1

Diabetes Mellitus, Type 1

New Zealand
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals (CARegT1D)

Type 1 Diabetes

France
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
University of Copenhagen
Rigshospitalet, Denmark

Recruiting

The Role of GIP in Postprandial Splanchnic Blood Flow Distribution and Metabolism in Patients With Type 2 Diabetes (GA-17b)

Blood Flow

Denmark
China-Japan Friendship Hospital

Recruiting

The Effects of Low-Dose Versus High-Dose Intravenous IRON Therapy with Ferric Derisomaltose in Patients with Chronic Heart Failure and Iron Deficiency (IRONDOSE)

Heart Failure | Iron Deficiency
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

Registry Study to Determine the Effectiveness and Safety of Weight Loss With Enavogliflozin in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Xie Kangjie

Recruiting

Predictive Effect of TGF-β Combined With INS-PI3K-AKT Signaling Pathway Related Proteins (ADNP, MAP6, Pgc-1α) for POD on Diabetes Patients

Diabetes | Postoperative Delirium

China
Beneficência Portuguesa de São Paulo

Not yet recruiting

Effectiveness of the Brazilian Diabetes Prevention Program (PROVEN-DIA)

Prediabetic State | Pre Diabetes
University of Ulster
Northern Health & Social Care Trust (NHSCT); Solvotrin Therapeutics - Active...

Not yet recruiting

Adiposity and Iron Requirements in Pregnancy (ADIPREG)

Iron Deficiency Anemia of Pregnancy

United Kingdom
University Hospital, Ghent
University Ghent

Not yet recruiting

24-hour Movement Behaviors in Adults With Type 1 Diabetes (24h-MBs_T1D)

Diabetes Mellitus, Type 1

Belgium

Search clinical trials for: Glutamine metabolism

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