Search clinical trials for: HDR monotherapy

Total 1755 results

University of California, San Francisco

Not yet recruiting

Two-fraction HDR Monotherapy for Localized Prostate Cancer

Prostate Adenocarcinoma | Localized Prostate Carcinoma

United States
CSSS de Gatineau

Active, not recruiting

Study of High-dose Rate (HDR) Monotherapy for Low and Intermediate Risk Prostate Cancer

Prostate Cancer

Canada
British Columbia Cancer Agency

Active, not recruiting

Comparison of HDR vs. LDR Brachytherapy as Monotherapy for Intermediate Risk Prostate Cancer

Prostate Cancer

Canada
Sunnybrook Health Sciences Centre

Active, not recruiting

MRI Assisted Focal Boost With HDR Monotherapy for Prostate Cancer Patients (MARS)

Prostate Cancer

Canada
CR-CSSS Champlain-Charles-Le Moyne

Completed

HDR Brachytherapy as Monotherapy for Low and Intermediate Risk Prostate Cancer (BRP2)

Prostate Cancer

Canada
Sunnybrook Health Sciences Centre

Terminated

Combined LDR Boost and HDR Whole Gland (Delight)

Carcinoma Prostate

Canada
CHU de Quebec-Universite Laval
Sunnybrook Health Sciences Centre; Université de Montréal

Completed

HDR Brachytherapy vs. LDR Brachytherapy Monotherapy in Localized Prostate Cancer (HDRvsLDR)

Prostate Cancer

Canada
Sunnybrook Health Sciences Centre

Unknown

A Phase II Trial of High Dose-Rate Brachytherapy as Monotherapy in Low and Intermediate Risk Prostate Cancer

Carcinoma of the Prostate

Canada
National Institute of Oncology, Hungary

Unknown

HDR vs LDR Brachytherapy as Monotherapy in the Treatment of Localized Prostate Cancer. (PROMOBRA)

Adenocarcinoma of Prostate

Hungary
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

Effectiveness and Clinical Outcomes of Long-term Bulevirtide Monotherapy in Patients With HDV-related Compensated Cirrhosis (SAVE-D)

Hepatitis D

Italy
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SSGJ-705 Monotherapy in Patients With Advanced Malignant Tumors

Locally Advanced, Recurrent or Metastatic Malignancies

China
Genmab
BioNTech SE

Recruiting

Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy

Malignant Solid Tumor

Spain
Centre Hospitalier Intercommunal Creteil
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis (ANTEIPA)

Bronchiectasis

France
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Phase II Study of SSGJ-707 Monotherapy in First-line PD-L1 Positive Advanced NSCLC Patients

NSCLC

China
7 Hills Pharma, LLC

Not yet recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Melanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditions

United States
Dow University of Health Sciences

Recruiting

Valacyclovir Monotherapy in Pain Management of Acute Periapical Abscesses After Emergency Chamber Opening (Antiviral)

Acute Apical Abscess

Pakistan
Northside Hospital, Inc.

Not yet recruiting

Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
University of Texas Southwestern Medical Center

Not yet recruiting

Use of DNA Testing and Gene Expression Profiling to Help Transition Kidney Transplant Recipients to Belatacept-only Immunosuppression

Kidney Transplant Immunosuppression

United States
Denise Fabian

Not yet recruiting

Hypofractionated Radiochemotherapy

Uterine Cervix Cancer

United States
Qing XIe

Recruiting

Pegylated Interferon α in Previously Interferon-treated CHB（Leading Study）

Chronic Hepatitis b

China
Xizang Haisco Pharmaceutical Co., Ltd

Recruiting

A Study for HSK39775 in Participants With Solid Tumors

Advanced Solid Tumors

China
Johnson & Johnson Enterprise Innovation Inc.

Recruiting

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Advanced Solid Tumors

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Efficacy of Combination of Hdroxyurea and Thalidomide Over Either Hydroxyurea or Thalidomide Alone in the Treatment of Transfusion Dependent Thalassemia in Children: A Quasi-Randomised Clinical Trial

Transfusion-dependent Thalassemia

Bangladesh
Incyte Biosciences Italy S.r.l

Recruiting

Study to Evaluate the Effectiveness of Tafasitamab in Combination With Lenalidomide Followed by Tafasitamab Monotherapy in Relapsed or Refractory Diffuse Large B-cell Lymphoma Non-transplant Eligible Patients in Italy (PRO-MIND)

DLBCL - Diffuse Large B Cell Lymphoma

Italy
Gustave Roussy, Cancer Campus, Grand Paris
Daiichi Sankyo

Recruiting

Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd (ICARUSBREAST02)

Advanced Breast Cancer | HER2-positive Metastatic Breast Cancer | Breast Cancer Metastatic | HER2 Low Breast Carcinoma

France
Biocad

Recruiting

A Study of the Efficacy and Safety of Monotherapy With BCD-264 and Darzalex in Subjects With Relapsed and Refractory Multiple Myeloma (DARVIVA)

Multiple Myeloma

Russian Federation
Al-Azhar University

Recruiting

Desmopressin Monotherapy for Monosymptomatic Nocturnal Enuresis

Nocturnal Enuresis

Egypt
National University Hospital, Singapore

Recruiting

Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions

Cervical Cancer

Singapore
Leiden University Medical Center
Dutch Colorectal Cancer Group; Stichting Darmkanker

Not yet recruiting

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer (DOSAGE)

Colorectal Cancer | Metastatic Cancer | Older Patients | Candidates for Palliative Chemotherapy

Netherlands
Incyte Biosciences Japan GK

Not yet recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Not yet recruiting

Phase 3 Study of TG103 Injection Monotherapy in Treatment of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Jinling Hospital, China

Recruiting

A Study of Multimodal Radiotherapy for Renal Cell Carcinoma Progressed After Prior Immunotherapy

Renal Cell Carcinoma | Radiotherapy | Immune Checkpoint Inhibitor

China
Ruijin Hospital

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS

Myelodysplastic Syndromes | Myelodysplastic Syndrome With Excess Blasts-2 | Myelodysplastic Syndrome With Excess Blasts-1

China
Korea Institute of Oriental Medicine

Recruiting

Efficacy and Safety of Combination Therapy With Bojungikki-tang and Pembrolizumab Monotherapy in Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Korea, Republic of
Strand Therapeutics Inc.

Recruiting

Study of IT STX-001 in Patients With Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

Advanced Solid Tumor

United States, Australia
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Multicenter, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Gastric or Gastroesophageal Junction Adenocarcinoma (G-HOPE-001)

Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

China
Novartis Pharmaceuticals

Recruiting

Study of Efficacy and Safety of LCZ696/Amlodipine in Grade 1 and 2 Hypertension Patients Uncontrolled by LCZ696 Monotherapy

Hypertension

Japan
BeiGene

Recruiting

Study of BG-C9074 as Monotherapy and in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia
Yonsei University

Not yet recruiting

Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)

Peripheral Artery Disease | Polyvascular Disease

Korea, Republic of
Shenzhen TargetRx, Inc.
Institute of Hematology & Blood Diseases Hospital, China

Recruiting

TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Non Hodgkin Lymphoma | Hematologic Malignancy | Acute Lymphoblastic Leukemia, Adult

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Study of TQB2930 for Injection Monotherapy or Combination Therapy in Patients With Recurrent/Metastatic Breast Cancer

Metastatic Breast Cancer | Advanced Malignancies | Recurrent Breast Cancer

China
Shengjing Hospital

Not yet recruiting

Study of Cadonilimab (AK104) Plus Eribulin vs. Eribulin Monotherapy for Recurrent or Metastatic Triple-negative Breast Cancer

Triple Negative Breast Cancer

China
British Columbia Cancer Agency
University of British Columbia; Vancouver Prostate Centre; BC Cancer Foundation

Recruiting

Multi-omic Approach to Study HDR Brachytherapy for Favorable Risk and Low Tier Intermediate Risk Prostate Cancer (BrachyTRACKS)

Localized Prostate Carcinoma

Canada
Fujian Cancer Hospital

Not yet recruiting

MRI-based Signatures for Survival Prediction in Cervical Cancer With Radiotherapy

MRI | Cervical Cancer | Radiotherapy | Prognostic Model

China
The Hong Kong Polytechnic University
Alcon Research

Recruiting

Efficacy of a New Nanoemulsion Artificial Tear in Dry Eye Disease Management

Dry Eye Syndromes

Hong Kong
Saint Vincent's Hospital, Korea

Recruiting

Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention (ALMIGHTY)

Coronary Artery Disease | Dyslipidemias | Primary Prevention

Korea, Republic of
Azienda Ospedaliero Universitaria Maggiore della...

Recruiting

Treatment of BPH With CO2 Serenoa +PEA as Monotherapy or in Combination With Tamsulosin: ProSeRePEA Trial (ProSeRePEA)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia | Urinary Obstruction

Italy
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Dermatitis Atopic

Japan, China, Spain, United States, Argentina, United Kingdom, Denmark, Sweden, Turkey
Leiden University Medical Center
Radboud University Medical Center; University Medical Center Groningen; Erasmus... and other collaborators

Recruiting

Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection (RiCOTTA)

Prosthetic-joint Infection | Infection Hip | Infection; Knee, Joint

Netherlands

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