Search clinical trials for: HMGB1 Protein

Total 21986 results

SPARK Biopharma

Completed

SB17170 Phase1 Trial in Healthy Volunteer

Pharmacokinetics | Pharmacodynamics | Safety Issues | Tolerability

Korea, Republic of
Assiut University

Not yet recruiting

MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy

Drug Resistant Epilepsy
Rennes University Hospital

Completed

Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages (MacFibOsis)

History of Exposure to Silica or Asbestosis | Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases

France
Karolinska University Hospital

Completed

HMGB1 in ICU-survivors

Sepsis | Cognitive Impairment

Sweden
Hospital Israelita Albert Einstein
Ohio State University; Federal University of São Paulo

Completed

Ostearthritis Biomarkers and Rehabilitation (Knee)

Osteoarthritis

Brazil
Jing Li

Unknown

Impact of HMGB1 on Diastolic Dysfunction in Hypertensive Patients

Inflammation | Hypertension | Diastolic Dysfunction
Xingui Dai

Completed

HMGB1 Release From Hemorrhagic Shock Patients

Hemorrhagic Shock | Intensive Care Unit | Adult Disease

China
Seoul St. Mary's Hospital

Unknown

Clinical Implications of HMGB1 in Patients Treated With Chemotherapy or Hematopoietic Stem Cell Transplantation (CHIP-SCT)

Acute Graft-versus-host Disease

Korea, Republic of
University Hospital, Grenoble
University Hospital, Marseille

Recruiting

Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322) (DYSALARM-322)

Lupus Erythematosus, Systemic

France
Yonsei University

Completed

The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity

Vitiligo

Korea, Republic of
Tongji Hospital

Not yet recruiting

Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study

Postoperative Analgesia
The First Affiliated Hospital of Soochow University

Not yet recruiting

Treatment of High-risk Newly Diagnosed Multiple Myeloma With Minimal Residual Disease Detection

Multiple Myeloma | Newly Diagnosed | MRD | High Risk
Gruppo Italiano Malattie EMatologiche dell'Adulto
Fundacion Espanola para la Curacion de la Leucemia Mieloide Cronica

Not yet recruiting

PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML (PEARL)

Chronic Myeloid Leukemia | Chronic Myeloid Leukemia, Chronic Phase | CML, Chronic Phase | Chronic Myeloid Leukemia, BCR/ABL-Positive
University Hospital, Angers

Not yet recruiting

Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation, a Multicenter Cluster Randomized Study (ALHERT)

Leukemia, Lymphoma, Multiple Myeloma

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

FOLFOX Plus Lenvatinib Adjuvant Therapy for Hepatocellular Carcinoma Post-Liver Transplantation

Liver Cancer | Liver Transplant

China
Maastricht University Medical Center
Jessa Hospital

Not yet recruiting

The Impact of Physical Activity Versus Dietary Energy Restriction on Tumour and Muscle Protein Synthesis in Prostate Cancer Patients (DIRECT)

Cancer of Prostate
Henan Cancer Hospital

Recruiting

A Phase II Clinical Study of Cadonilimab in Treatment-naïve or Relapsed Extensive Small Cell Lung Cancer

Extensive Small Cell Lung Cancer

China
Hunan Cancer Hospital

Recruiting

Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Shanghai Changzheng Hospital
CARsgen Therapeutics Co., Ltd.

Not yet recruiting

Study of CT071 Injection in HRNDMM

High-risk Newly Diagnosed Multiple Myeloma (HRNDMM)
Maastricht University Medical Center
Cargill

Not yet recruiting

Plant Protein Blend and Milk Protein Supplements in Older Individuals (Blend-D2O)

Sarcopenia | Skeletal Muscle Atrophy | Protein Malnutrition
Kafrelsheikh University

Not yet recruiting

Locally Delivered Whey Protein Nanoparticles Gel in Stage II Grade B Periodontitis

Periodontitis Chronic Localized Slight

Egypt
Babol University of Medical Sciences

Not yet recruiting

Role of NLRP6 in Chronic Periodontitis

Chronic Periodontitis
Children's Oncology Group

Not yet recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor
University of Missouri-Columbia

Recruiting

Baker Gordon Syndrome Natural History Study (BAGOS)

Epilepsy, Generalized | Sleep Disorder | Rare Diseases | Development Delay | Motor Delay | Autism or Autistic Traits | SYT-SSX Fusion Protein Expression

United States
Celgene
Bristol-Myers Squibb

Recruiting

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation (KarMMa-9)

Multiple Myeloma

Austria, United States, Spain, Australia, Japan, France, Israel, Italy, Canada, Greece, Belgium, Norway, Romania, Czechia, Denmark, Germany, Korea, Republic of, United Kingdom, Poland
Maastricht University Medical Center

Not yet recruiting

Three Channel Food Concept: the Effect Meal Service on Food Intake During Hospitalization

Protein-Energy Malnutrition | Nutrition Poor

Netherlands
Rise Therapeutics LLC

Not yet recruiting

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

Melanoma | Basal Cell Carcinoma | Squamous Cell Carcinoma | Melanoma Recurrent | Squamous Cell Cancer | Basal Cell Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
Complement Theory Inc.

Not yet recruiting

A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live 1:1 Exercise Coaching and Personalised Digital Application on Cancer Survivors' Cost of Care

Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Other Cancer
CSL Behring

Not yet recruiting

Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Chinese Subjects With Hemophilia B Previously Treated With FIX Therapy

Hemophilia B
OHSU Knight Cancer Institute
Oregon Health and Science University

Not yet recruiting

Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Brazilian Clinical Research Institute
Alliança Diagnostic

Not yet recruiting

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke (ARCHIMEDES)

Ischemic Stroke
Shanghai Yao Yuan Biotechnology Ltd. (also known...

Not yet recruiting

Evaluating the Safety and Tolerability of Multiple Doses of Orally Administered DF-003 in ROSAH Syndrome Patients

ROSAH

Australia, United States
Ohio State University

Not yet recruiting

Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)

Preterm Birth | Pregnancy, High Risk | Preterm Premature Rupture of Membrane

United States
Chiesi Farmaceutici S.p.A.

Recruiting

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Chronic Obstructive Pulmonary Disease

Bulgaria
Aalborg University Hospital
University of Aarhus

Not yet recruiting

Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect

Amyotrophic Lateral Sclerosis | Pseudobulbar Affect
Shanghai Zhongshan Hospital

Not yet recruiting

The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis

Glucocorticoid Resistant ICIs-related Myocarditis
Changhai Hospital
Shanghai Chest Hospital; Shanghai Changzheng Hospital; First Affiliated Hospital... and other collaborators

Recruiting

High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib

Non-Small Cell Lung Cancer

China
Nimble Science Ltd.

Not yet recruiting

The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule

Nutrition | Microtia | Amino Acid Change | Food Science | Digestion Rate

Canada
Narendranath Epperla
Eli Lilly and Company

Not yet recruiting

Pirtobrutinib With Rituximab for the Treatment of Newly Diagnosed Marginal Zone Lymphoma

Marginal Zone Lymphoma

United States
Peking University People's Hospital
Henan Cancer Hospital; Wuhan Union Hospital, China; Zhejiang University; Peking... and other collaborators

Not yet recruiting

The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP

Chronic Myeloid Leukemia

China
AbbVie

Not yet recruiting

A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis (Sleep Up)

Sleep Disturbance | Atopic Dermatitis
St. Jude Children's Research Hospital
AbbVie

Not yet recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

T-cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
Guangdong Provincial People's Hospital

Not yet recruiting

PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS

Colorectal Cancer
Beijing Tiantan Hospital
Beijing University of Chemical Technology; Beijing Healthunion Cardio-Cerebrovascular...

Not yet recruiting

Nerve Growth Factor Encapsulated With 2-methacryloyloxyethyl Phosphorylcholine Nanocapsules in the Treatment of Amyotrophic Lateral Sclerosis (NATURAL)

Amyotrophic Lateral Sclerosis
New Valley University

Not yet recruiting

Characterizing Diversity and Antifungal Resistance in Immunocompromised ICU Patients With Respiratory Tract Infections

Immunocompromised ICU Patients With Respiratory Tract Infections
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Harbin Medical University

Not yet recruiting

HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer

Biliary Tract Cancer
Peking Union Medical College Hospital
Peking University; Shanghai Huilun Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS (STAR)

Acute Respiratory Distress Syndrome
AbbVie

Not yet recruiting

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab (Switch-Up)

Atopic Dermatitis

Search clinical trials for: HMGB1 Protein

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