Search clinical trials for: Healthy nontransplant without liver disease

Total 397751 results

St. Louis University
Mid-America Transplant

Active, not recruiting

Cytokeratin 18 Non-invasive Biomarker for Rejection in Liver Transplant Patients

Liver Transplant Rejection | Liver Transplant Failure and Rejection

United States
Boehringer Ingelheim

Recruiting

A Study to Test How Avenciguat (BI 685509) is Taken up in the Body of People With and Without Liver Problems

Liver Diseases | Healthy

United States
Takeda

Recruiting

A Study of TAK-279 in Adults With or Without Liver Damage

Healthy Volunteers | Hepatic Impairment

United States
Amgen

Active, not recruiting

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke (VESALIUS-CV)

Coronary Heart Disease (CHD)

Canada, France, United States, Spain, United Kingdom, Korea, Republic of, Netherlands, Austria, Australia, Czechia, Taiwan, Finland, Hungary, Italy, Poland, Greece, Germany, Brazil, Latvia, Denmark, Mexico, Russian Federation, Bulgaria and more
Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT

Healthy Volunteers | Hepatic Impairment

United States
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
Boehringer Ingelheim
Zealand Pharma

Completed

A Study to (1) Compare How BI 456906 is Taken up in the Body of Healthy People and People With Liver Problems and (2) Find Out How People With Overweight and Obesity, With and Without Liver Problems, Tolerate Different Doses of BI 456906

Liver Diseases | Healthy | Obesity

Germany, United States, Hungary, New Zealand, Slovakia, Poland
Boehringer Ingelheim
IQVIA global CRO

Completed

A Study to Test How BI 690517 is Taken up in the Body of People With and Without Liver Problems

Liver Diseases | Healthy

United States
Eiger BioPharmaceuticals

Completed

Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a (D-LIVR)

Hepatitis Delta Virus

United States, Belgium, Spain, Greece, Canada, Italy, Romania, Germany, Israel, Bulgaria, Taiwan, Turkey, Pakistan, Sweden, Ukraine, New Zealand, Russian Federation, United Kingdom, Moldova, Republic of, France, Mongolia, Switzerland
GlaxoSmithKline

Completed

Assess if Immune Response of GSK Biologicals' Tritanrix™-HepB/Hib-MenAC Given Without or With Hepatitis B Vaccine at Birth is at Least as Good as Tritanrix™-HepB/Hiberix™ Without Hepatitis B Vaccine at Birth, When Given to Healthy Infants

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis

Philippines
Dong-A Pharmaceutical Co., Ltd.

Completed

A Pharmacokinetic Study of Udenafil in Adult Subjects With or Without Impaired Hepatic Function (udenafil)

Hepatic Impairment

Korea, Republic of
CRITT Bio-Industries
BioFortis; NUTRITIS

Unknown

Glycemic and Insulinemic Index Determination of Two Products: Fructilight® and A Fruit Fructo-Oligosaccharides in Sweet Matrix (IGNUT)

Healthy

France
GlaxoSmithKline

Completed

Comparison of Immuno, Reacto and Safety of Recombinant Hepatitis B Vaccine With or Without MPL in Healthy Older Adults

Hepatitis B

Austria, Belgium, Denmark, Iceland
Immutep S.A.S.
SGS Aster-Cephac (CRO)

Completed

A Randomized Phase I Study of a Hepatitis B Antigen Combined With IMP321

Healthy

France
Seoul National University Hospital

Recruiting

Safety of DNP007 in Healthy Subjects

Liver Transplant; Complications | Steatohepatitis, Nonalcoholic | Liver Transplant Rejection

Korea, Republic of
AstraZeneca

Recruiting

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone

Hepatic Impairment

United States
VarmX B.V.

Recruiting

Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant

Coagulation Disorder

Netherlands
Kylonova (Xiamen) Biopharma co., LTD.

Recruiting

Dose Escalation Study of Kylo-0603 in Healthy Subjects

Nonalcoholic Steatohepatitis

China
Boehringer Ingelheim

Recruiting

A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems

Healthy | Renal Impairment

Germany
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Shanghai Henlius Biotech

Not yet recruiting

A Study to Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 With or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients.

Carcinoma, Hepatocellular
Active Genomes Expressed Diagnostics, Corp
Walter Reed National Military Medical Center; Arizona Clinical Trials

Not yet recruiting

AGED Diagnostics Liver Disease Assessment (AGEDDX)

Healthy | NAFLD | NASH With Fibrosis

United States
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Healthy
Novo Nordisk A/S

Not yet recruiting

A Research Study on Etavopivat in Participants With and Without Liver Disease

Liver Diseases

United States
Bettina Mittendorfer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Not yet recruiting

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Healthy | Obesity | Diabetes Type 2 | Nonalcoholic Fatty Liver

United States
Vanderbilt University Medical Center

Not yet recruiting

Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease

Alzheimer Disease | Caregiver Burden | Dysphagia | Healthy Aging | Dysphonia
McGill University Health Centre/Research Institute...

Not yet recruiting

Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients With Type 1 Diabetes (T1D) (AFS_T1D)

Healthy Subjects | Type 1 Diabetes (T1D)
University of Alabama, Tuscaloosa
McCormick Science Institute

Recruiting

Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile

Cardiometabolic Syndrome

United States
Chiang Mai University
Faculty of Medicine, Chiang Mai University

Not yet recruiting

Immunogenicity and Safety of Inactivated and Live-attenuated HAV Vaccine Among Thai Healthy Children and Adolescents (HAV-RCT)

Hepatitis A | Vaccine-Preventable Diseases | Hep A | HAV
AstraZeneca

Not yet recruiting

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Takeda

Recruiting

A Study of the Interaction of Other Drugs With TAK-279 in Healthy Adults

Healthy Volunteers

United States
Università degli Studi di Sassari
Dr. Dario Melodia; Dr. Milena Pisano; Prof. Silvio Mario Meloni; Prof. Edoardo... and other collaborators

Not yet recruiting

Soi TS3 Surface in Patients With and Without Type 2 Diabetes

Dental Implant | Dental Implant-Abutment Design

Italy
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
Chang Gung Memorial Hospital

Not yet recruiting

Efficacy Evaluation of Chang Geng Healthy Drink on Patients With Non-alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease
University of Copenhagen
Bispebjerg Hospital

Not yet recruiting

Direct Versus Indirect Effect of Amino Acids on Hepatokines (Diaakine)

Obesity | Non-Alcoholic Fatty Liver Disease

Denmark
Bellus Health Inc. - a GSK company

Recruiting

A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years of Age

Cough

United States
Changchun Intellicrown Pharmaceutical Co. LTD

Recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effects of IMM-H014 in Healthy Subjects

Nonalcoholic Steatohepatitis (NASH)

China
Region Skane
Lund University; Helsinki University Central Hospital; The George Institute for... and other collaborators

Recruiting

Stepcare Extended Follow-up Substudy

Cognitive Impairment | Caregiver Burden | Hypoxia, Brain | Cardiac Arrest With Successful Resuscitation

Sweden, Finland, New Zealand, Australia, Germany, Luxembourg
Jelizaveta Sokolovska
Medical University of Graz; Spindox Labs; The National Research Council, Italy; The Institute of Electronics and Computer Sciences, Latvia and other collaborators

Not yet recruiting

Development of PI-ML Algorithm for Prediction of the Real-time Risk for Developing Pre-diabetes (PRAESIIDIUM)

Body Weight | Prediabetic State | Overweight or Obesity | Life Style, Healthy

Latvia
Novo Nordisk A/S

Recruiting

A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children.

Healthy Volunteers (Non-alcoholic Steatohepatitis)

Austria
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
Best Healthcare Inc.

Not yet recruiting

Persistence of Hepatitis A Antibody in Healthy Adults ~32 Years Post Vaccination.

Hepatitis A
Mitsubishi Tanabe Pharma America Inc.

Recruiting

INcreased Sun Exposure Without Pain In Research Participants With EPP or XLP (INSPIRE)

Erythropoietic Protoporphyria (EPP) | X-Linked Protoporphyria (XLP)

United States, Spain, France, Japan, United Kingdom, Italy, Australia, Poland, Bulgaria, Czechia, Netherlands
AstraZeneca

Recruiting

A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants

Healthy Participants

United States
Novo Nordisk A/S

Recruiting

A First Human Dose Study Investigating Safety and Concentration of Study Medicine in the Blood Following Once Daily Oral Dosing of NNC0560-0004 in Healthy Adults.

Healthy Volunteers - Liver Diseases

United Kingdom
University Medicine Greifswald

Not yet recruiting

Dose-dependent Kinetics of Thiamin in Healthy Volunteers With and Without Functional OCT1 Hepatic Transporters (THIAMO-1)

Healthy

Germany
Fudan University

Recruiting

Postoperative Chemotherapy With/Without Radiotherapy and Immunotherapy for Colorectal Liver Metastases With High Risk of Locally Recurrence (IMPROVE)

Colorectal Cancer | Liver Metastases | Radiotherapy | Immunotherapy

China
Ausper Biopharma Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and Chronic Hepatitis B Patients

Hepatitis B, Chronic

China
Sohag University

Not yet recruiting

The Impact Of SGLT2 -I on Metabolic Dysfunction -Associated Steatotic Liver Disease In Patients With Type 2 Diabetes Mellitus

Fatty Liver, Nonalcoholic

Search clinical trials for: Healthy nontransplant without liver disease

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