Search clinical trials for: Heme arginate

Total 333 results

Alnylam Pharmaceuticals

Completed

A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)

Acute Intermittent Porphyria

United States, United Kingdom, Sweden
University of Edinburgh
Kidney Cancer UK

Terminated

Heme Arginate in Transplantation Study (HOT2)

Renal Transplant Rejection | Renal Transplant Failure

United Kingdom
Martin Andreas, M.D.
National Bank of Austria; Orphan Medical

Completed

The Effects of Intravenous Heme Arginate on Heme Oxygenase-1 Expression (HO-1) and Oxidative Stress in the Human Heart

Myocardial Ischemia

Austria
University of Edinburgh
NHS Lothian

Completed

Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation (HOT)

Ischemia-reperfusion Injury | Graft Failure

United Kingdom
University of Edinburgh
Medical Research Council; NHS Lothian

Unknown

Heme Arginate in Cardiac Surgery Patients (HACS)

Acute Kidney Injury

United Kingdom
Daniel Doberer

Completed

Effects of Heme Arginate in Healthy Male Subjects (HEMAHS)

Healthy Subjects | Genetic Polymorphism | Heme Oxygenase

Austria
MWolzt

Unknown

Heme Arginate in Functional Magnetic Resonance Imaging (fMRI)

Ischemia-reperfusion Injury

Austria
Radboud University Medical Center
Dutch Diabetes Research Foundation

Terminated

Heme Oxygenase (HO) Activity and Adenosine Induced Vasodilation

Atherosclerotic Cardiovascular Disease

Netherlands
University Medical Center Groningen

Completed

Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction? (HAEM)

Acute Myocardial Infarction

Netherlands
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

Porphyria
National Center for Research Resources (NCRR)
University of Texas

Completed

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Porphyria

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria

Porphyria
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria

Porphyria
Virginia Commonwealth University

Not yet recruiting

Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality (REMAIN1)

Acute Myeloid Leukemia

United States
University Hospital, Ghent
Algemeen Ziekenhuis Maria Middelares; Onze Lieve Vrouwziekenhuis Aalst; AZ Jan... and other collaborators

Recruiting

Move ARound And Get Active: an Intervention to Optimize 24-hour Movement Behaviours in Preschoolers (MARGA)

Sleep | Parenting | Parents | Child Behavior | Sedentary Behavior | Sedentary Time | Child Obesity | Physical Inactivity

Belgium
PathMaker Neurosystems Inc.
Spaulding Rehabilitation Hospital; Muscular Dystrophy Association; Sean M. Healey...

Recruiting

Early Feasibility Study of the MyoRegulator® for Treatment of ALS (ALSEFS)

Amyotrophic Lateral Sclerosis

United States
Cornell University

Recruiting

Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption (FeMicrobiome)

Iron Overload | Anemia, Iron Deficiency

United States
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Anemia, Sickle Cell

United States
Jubilee Mission Medical College and Research Institute

Recruiting

HEAVEN CRITERIA vs Modified LEMON Score for Predicting Difficult Intubation

Intubation Complication | Intubation; Difficult or Failed

India
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan Anemia

Steroid-refractory Diamond-Blackfan Anemia (DBA)

United States
Leiden University Medical Center

Recruiting

The ICU-recover Box, Using Smart Technology for Monitoring Health Status After ICU Admission

Critically Ill | ICU Survivor | User Experience

Netherlands
Masonic Cancer Center, University of Minnesota

Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditions

United States
Hemerion Therapeutics

Recruiting

A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma

Primary Glioblastoma

United States
IHF GmbH - Institut für Herzinfarktforschung

Not yet recruiting

BENTO - Bronchoscopic Lung Volume Reduction in Severe Emphysema Using Thermoablation

Emphysema or Chronic Obstructive Pulmonary Disease

Germany
Nikolaj Frost MD
Roche Pharma AG; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus...

Recruiting

Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma (ANTELOPE)

Non-Small Cell Lung Cancer Metastatic

Germany
Bristol-Myers Squibb

Recruiting

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE) (POETYK SLE-1)

Systemic Lupus Erythematosus

United States, Brazil, China, Germany, Italy, France, Mexico, Poland, Puerto Rico, Argentina, Canada, Colombia, Hong Kong, Peru, Romania, Portugal, Korea, Republic of, Turkey, Ireland, India, Lithuania, Bulgaria, Slovakia
University of Alabama at Birmingham

Recruiting

Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry (CARE-Heme)

Multiple Myeloma | Amyloidosis | Plasma Cell Leukemia

United States
NovoCure GmbH

Recruiting

TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma Study (TIGER Meso)

Pleural Mesothelioma

Germany, Italy
Dana-Farber Cancer Institute

Recruiting

Home Transfusion for HEME

Hematologic Malignancy

United States
University Hospital, Basel, Switzerland
Clinical Trial Unit, University Hospital Basel, Switzerland

Recruiting

Detection of an Endovascular Treatment Target in Patients With an Acute, Spontaneous Intracerebral Hemorrhage (HemEXPLO)

Intracerebral Hemorrhage | Nontraumatic Intracerebral Hemorrhage

Switzerland
Gilead Sciences
Arcus Biosciences, Inc.

Recruiting

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer (STAR-121)

Non-small Cell Lung Cancer

Taiwan, Hong Kong, United States, Netherlands, United Kingdom, Italy, Korea, Republic of, Spain, Israel, Japan, France, Portugal, China, Turkey, Brazil, Mexico, Austria, Germany, Belgium, Chile, Argentina, Singapore, Canada
Technische Universität Dresden
Roche Pharma AG

Recruiting

A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung (LCNEC-ALPINE)

Large Cell Neuroendocrine Carcinoma of the Lung

Germany
Cloudbreak Therapeutics, LLC

Recruiting

A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium

Pterygium

United States, China, India, Australia, New Zealand
Novartis Pharmaceuticals

Recruiting

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation

Italy, Spain, United States, France, Thailand, Malaysia, China, Germany, India, Turkey, Belgium, Argentina, Bulgaria, Netherlands, Hungary, Greece, Portugal, Austria, Singapore, Brazil, United Kingdom
University of Illinois at Chicago

Recruiting

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma (HEME-18)

Multiple Myeloma

United States
Hangzhou Sumgen Biotech Co., Ltd.

Recruiting

SG2501 Safety Study in Subjects With Relapsed or Refractory Hematological Malignancies and Lymphoma.

Lymphoma | Hematological Malignancy

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Wake Forest University Health Sciences; Arizona... and other collaborators

Recruiting

Wellness App for Sleep Disturbance in Hematological Cancer Patients (Heme)

Depression | Inflammation | Cancer | Fatigue | Anxiety | Sleep Disturbance

United States
United Therapeutics

Recruiting

Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis (TETON-2)

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease

Taiwan, Belgium, Spain, Korea, Republic of, Germany, Australia, Chile, Denmark, France, Mexico, Israel, Italy, Netherlands, Argentina, New Zealand, Peru
University of Illinois at Chicago

Recruiting

Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD (HEME-20)

Multiple Myeloma

United States
Jacob Moller
Rigshospitalet, Denmark; University Hospital Bispebjerg and Frederiksberg; Hillerod... and other collaborators

Recruiting

The Cardiac Effects of Empagliflozin in Patients With High Risk of Heart Failure

Heart Failure | Obesity

Denmark
Hemex Health

Recruiting

Gazelle COVID-19 Test Clinical Accuracy Protocol

Covid19

United States
University Hospital, Ghent

Recruiting

Data Collection of Patients Admitted to the Stroke Unit (PRODA-STROKE)

Stroke | Stroke, Ischemic | Stroke, Acute | Stroke Sequelae | Stroke Hemorrhagic

Belgium
Merck Sharp & Dohme LLC

Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Von Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated Cancers

Canada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
University of Leipzig

Recruiting

Nasal High-flow Compared to Non-invasive Ventilation in Treatment of Acute Acidotic Hypercapnic Exacerbation of Chronic Obstructive Pulmonary Disease

COPD Exacerbation Acute

Germany
AstraZeneca
Iqvia Pty Ltd

Recruiting

Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus (Tulip SC)

Systemic Lupus Erythematosus

Germany, Hungary, Japan, Mexico, United States, Argentina, Bulgaria, Chile, Colombia, Peru, Poland, Spain, Ukraine, United Kingdom, Russian Federation
University Hospital, Angers

Recruiting

Effectiveness of Coordinated Care to Reduce the Prolonged Disability Risk Among Patients Suffering From Low Back Pain in Primary Care (COLOMB)

Low Back Pain

France
PathMaker Neurosystems Inc.
National Institute of Neurological Disorders and Stroke (NINDS); Spaulding...

Recruiting

Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity (RECOVER)

Stroke | Muscle Spasticity

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Is Clonal Hematopoiesis of Indeterminate Potential Associated With Unprovoked Pulmonary Embolism? (HEMEP)

Pulmonary Embolism | Hematopoiesis

France
University of Miami

Recruiting

Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma

Renal Cell Carcinoma | Calcium Oxalate Urolithiasis

United States
University of Miami

Recruiting

Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy.

Nephrolithiasis | Urosepsis

United States

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