Search clinical trials for: Hypogammaglobulinemia

Total 31 results

Monash University

Recruiting

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension (RATIONALISE)

Hypogammaglobulinemia | Haematological Malignancy

Australia
Grifols Therapeutics LLC

Recruiting

A Study to Evaluate Efficacy, Safety, and Pharmacokinetics of XEMBIFY® Plus Standard Medical Treatment (SMT) Compared to Placebo Plus SMT to Prevent Infections in Participants With Hypogammaglobulinemia and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia

Bacterial Infections | B-cell Chronic Lymphocytic Leukemia | Hypogammaglobulinemia

United States, Bulgaria, Poland, Romania, Serbia
Insel Gruppe AG, University Hospital Bern

Recruiting

Immunoglobulin Deficiency a Treatable Cause of Fatigue in Patients With Multiple Sclerosis (MS)? (FatIgG)

Multiple Sclerosis | Fatigue | Hypogammaglobulinemia

Switzerland
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
Kedrion S.p.A.

Recruiting

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in Pediatric PID Patients (KIDCARES10) (KIDCARES10)

Primary Immunodeficiency Disease

Italy, United States, Portugal, Hungary, Russian Federation, Slovakia
Octapharma

Recruiting

Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients With Chronic Lymphocytic Leukemia ("PRO-SID" Study)

Chronic Lymphocytic Leukemia | Hypogammaglobulinemia

United States, Denmark, Germany, Hungary, Italy, Poland, Russian Federation, Spain, Czechia, Greece, Israel, Turkey
National Institute of Allergy and Infectious Diseases...

Recruiting

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

Infections | Warts | Neutropenia | Leukopenia | Myelokathexis

United States
X4 Pharmaceuticals

Active, not recruiting

Efficacy and Safety Study of Mavorixafor in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome

WHIM Syndrome

United States, Denmark, Australia, Austria, France, Hungary, Israel, Italy, Korea, Republic of, Netherlands, Russian Federation, Spain, Turkey
X4 Pharmaceuticals

Completed

A Dose Determination and Safety Study of X4P-001 (Mavorixafor) in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome

WHIM Syndrome

Australia, United States
National Institute of Allergy and Infectious Diseases...

Completed

Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome

Infections | Warts | Neutropenia | Myelokathexis | Hypogammaglobulinemia

United States
Kedrion S.p.A.

Completed

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in PID Patients (CARES10)

Primary Immunodeficiency Disease

United States
Baxalta now part of Shire

Completed

Safety, Pharmacokinetic and Efficacy Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Patients With Primary Immunodeficiency (Hypo- or Agammaglobulinemia)

Primary Immunodeficiency Diseases (PID) | Hypogammaglobulinemia | Agammaglobulinemia

Finland, Sweden
Kedrion S.p.A.

Completed

Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID)

Primary Immunodeficiency | Hypogammaglobulinemia | Agammaglobulinemia | Antibody Deficiency

United States, Canada
Mazandaran University of Medical Sciences

Unknown

Rituximab-Induced Hypogammaglobulinemia in Multiple Sclerosis

Multiple Sclerosis | Hypogammaglobulinemia

Iran, Islamic Republic of
Advanced Neurosciences Institute
Novel Pharmaceutics Institute

Unknown

Immunodeficiency in MS

Multiple Sclerosis | Infection, Bacterial | Immunodeficiency | Hypogammaglobulinemia

United States
Brigham and Women's Hospital

Completed

Personalized Immunotherapeutic for Antibiotic-resistant Infection

Infection | Immune Deficiency | Hypogammaglobulinemia | Septic Arthritis | Mycoplasma Hominis

United States
BriovaRx Infusion Services

Terminated

Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)

Primary Immune Deficiency Disorder

United States
University Health Network, Toronto
CSL Behring

Completed

Subcutaneous Ig in Allogeneic Stem Cell Transplant Recipients (ScIGalloHCT)

Hypogammaglobulinemia

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Fatigue | Thrombocytopenia | Fever | Chronic Lymphocytic Leukemia | Lymphadenopathy | Small Lymphocytic Lymphoma | Hypogammaglobulinemia | Lymphocytosis | Night Sweats | Paraproteinemia

United States
Columbia University
Grifols Therapeutics LLC

Completed

Intravenous Immunoglobulin (IVIG) in Lung Transplantation

Lung Transplantation | Hypogammaglobulinemia

United States
X4 Pharmaceuticals

Withdrawn

A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome

WHIM Syndrome
M.D. Anderson Cancer Center
Celgene Corporation

Terminated

Lenalidomide as Immune Adjuvant in Patient's With Chronic Lymphocytic Leukemia (CLL)

Hematologic Disorder

United States
University of Alabama at Birmingham
Grifols Biologicals, LLC

Completed

Post-bypass Prophylactic IVIG in Infants and Neonates

Congenital Heart Disease | Hypogammaglobulinemia

United States
O & O Alpan LLC

Unknown

Investigation of Immune Disorders and Deficiencies

Autoimmune Diseases | Hypogammaglobulinemia | Inflammatory Diseases | Primary Immune Deficiencies | Common Variable Immune Deficiencies

United States
Turku University Hospital

Unknown

Clinical and Virological Efficacy of Pegylated Interferon Alpha in the Treatment of Rhinovirus Infection in Patients With Primary Hypogammaglobulinemia: Randomized Controlled Trial (Hypogamma Int1)

Rhinovirus Infection

Finland
Bio Products Laboratory

Completed

Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.

Primary Immunodeficiency | Wiskott-Aldrich Syndrome | Hypogammaglobulinemia | Common Variable Hypogammaglobulinemia | X-linked Hypogammaglobulinemia | Immunodeficiency With Hyper-IgM

United States
CSL Behring

Completed

Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)

Common Variable Immunodeficiency | Agammaglobulinemia | IgG Deficiency

United States
CSL Behring

Completed

Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)

Common Variable Immunodeficiency | Agammaglobulinemia | IgG Deficiency
CSL Behring

Completed

Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)

Common Variable Immunodeficiency | Agammaglobulinemia | IgG Deficiency
The Cleveland Clinic

Completed

Cytomegalovirus Hyperimmune Globulin (CMV-Ig) Replacement in Hypogammaglobulinemic Lung Transplant Recipients

Hypogammaglobulinemia

United States
Prothya Biosolutions

Completed

Kinetics, Efficacy and Safety of IVIG-L in Hypogammaglobulinemia Patients

Hypogammaglobulinemia

Netherlands

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