Search clinical trials for: Immune system activity

Total 256033 results

Q32 Bio Inc.

Not yet recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

IgA Nephropathy | Lupus Nephritis (LN) | C3 (Complement Component 3) Glomerulopathy
Umm Al-Qura University

Recruiting

"Comparative Effect of Different Drugs Used to Tr€at Patients in Rheumatoid Arthritis Saudi Database (RASD)"

Rheumatoid Arthritis RA
Universidade do Porto
Research Centre in Physical Activity, Health and Leisure

Recruiting

Exercise as Intervention in Chronic Lymphocytic Leukemia (ADRENALINE)

Chronic Lymphocytic Leukemia

Portugal
Chinese PLA General Hospital

Not yet recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma
NovoCure GmbH

Recruiting

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

Metastatic Pancreatic Ductal Adenocarcinoma

Spain
Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Memorial Sloan Kettering Cancer Center
Seagen Inc.

Recruiting

A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

Hodgkin Lymphoma

United States
Assiut University

Not yet recruiting

Kappa Index Versus Csf Oligoclonal Bands in Diagnosis of ms and Prediction of Disease Activity

Multiple Sclerosis
University Hospital, Basel, Switzerland
University of Basel

Recruiting

REtinal Markers In Neuroinflammatory Diseases ("REMIND")

Multiple Sclerosis | Neuroinflammatory Diseases

Switzerland
Peking University Third Hospital

Recruiting

Exploring the Value of 18F-AlF-FAPI PET/CT in Assessing the Activity of Thyroid Eye Disease

Thyroid Eye Disease

China
Amgen

Recruiting

A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion

Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers

United States
University of Illinois at Chicago

Recruiting

Lifestyle Physical Activity Intervention for Persons Newly Diagnosed With Multiple Sclerosis

Multiple Sclerosis

United States
Jasper Therapeutics, Inc.

Recruiting

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines (SPOTLIGHT)

Chronic Inducible Urticaria

Germany
Washington University School of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Bridges2Scale: Testing Implementation Strategies

HIV/AIDS
University of Pavia
IRCCS National Neurological Institute "C. Mondino" Foundation; National Research...

Not yet recruiting

the EXPOSITION Study (EXPOSITION)

Multiple Sclerosis, Relapsing-Remitting | Environmental Exposure | Lifestyle Factors

Italy
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland
Shirley Ryan AbilityLab

Recruiting

Remote Therapeutic Monitoring Exercise Tracking

Multiple Sclerosis | Parkinson Disease

United States
Janssen Cilag S.A.S.

Recruiting

Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia (QOLIBRI)

Leukemia, Lymphocytic, Chronic, B-Cell

France
University of Manitoba
Juvenile Diabetes Research Foundation; Canadian Institutes of Health Research...

Not yet recruiting

Type 1 Diabetes, Exercise and Mentoring Trial (TEAM)

Physical Activity | Type 1 Diabetes
University of Colorado, Denver

Recruiting

Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults With Prediabetes (TExIS)

Obesity | PreDiabetes | Inactivity/Low Levels of Exercise

United States
Hospital of South West Jutland

Recruiting

Predictive Utility of a Short-term Improvement in Objectively Measured Physical Activity in Rheumatoid Arthritis (PUSIPA) (PUSIPA)

Fatigue | Rheumatoid Arthritis | Physical Inactivity | Fibromyalgia, Secondary

Denmark
M.D. Anderson Cancer Center

Not yet recruiting

Phase Ib/II Study Assessing the Clinical Activity and Safety of Brexucabtagene Autoleucel as a Consolidation in Patients With Relapsed/Refractory (R/R) and Newly Diagnosed B-cell Acute Lymphocytic Leukemia (ALL) Post Cytoreduction With Mini-HCVD-inotuzumab-blinatumomab/HCVAD-inotuzumab-blinatumomab

B-cell Acute Lymphocytic Leukemia | Relapsed/Refractory

United States
University of Saskatchewan
The Hospital for Sick Children; University of Calgary; Children's Hospital of...

Recruiting

Canadian Bone Strength Development Study (CanBSDS)

Type-1 Diabetes

Canada
Inonu University

Not yet recruiting

Online Physical Activity Tracking in Patients With Multiple Sclerosis

Multiple Sclerosis
Massachusetts General Hospital
BioSensics

Recruiting

Physical Activity Monitoring in Myasthenia Gravis

Myasthenia Gravis

United States
University of Washington

Recruiting

Increasing Physical Activity for Adults With Multiple Sclerosis (MS)

Fatigue | Multiple Sclerosis (MS) | Physical Inactivity

United States
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States
University of Maryland, Baltimore
National Institute on Aging (NIA)

Not yet recruiting

Behavioral Activation, Nutrition, and Activity Intervention

HIV

United States
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma (OLYMPIA-4)

B-Cell Non-Hodgkin Lymphoma (B-NHL)

Taiwan, Spain, Korea, Republic of, Thailand, Italy, Malaysia, Turkey, Australia
BicycleTx Limited

Recruiting

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

Metastatic Urothelial Cancer

United States
AbbVie

Not yet recruiting

Study of ABBV-383 Assessing Adverse Events and Clinical Activity With Subcutaneous (SC) Injection in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma
Eli Lilly and Company

Recruiting

A Study of LY3541860 in Adult Participants With Relapsing Multiple Sclerosis

Multiple Sclerosis

United States, Poland, Germany, Italy, France, Israel, Latvia, Lithuania, Slovakia, United Kingdom
University of Toronto

Recruiting

Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States (BTLP)

Physical Inactivity | Resistance Exercise | Amino Acids | Dietary Protein

Canada
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

Efficiency of Supervised Exercise Program Versus Mobile-Based Exercise Program in Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Turkey
AbbVie
Genmab

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma (EPCORE™FL-2)

Follicular Lymphoma (FL)

United States, Puerto Rico
Karolinska Institutet
Karolinska University Hospital; Region Örebro County; County Council of Norrbotten... and other collaborators

Recruiting

Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus (SLE-HIIT)

Lupus Erythematosus, Systemic

Sweden
Jasper Therapeutics, Inc.

Recruiting

Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU) (BEACON)

Chronic Spontaneous Urticaria

United States, Germany
AbbVie

Recruiting

Study Assessing Activity of Intravenous (IV) ABBV-383 Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

Israel, Taiwan
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving ABBV-383 as an Intravenous (IV) Infusion

Immunoglobulin Light Chain (AL) Amyloidosis

Japan, United States
Mayo Clinic

Not yet recruiting

Remote Monitoring With Health-Coaching to Improve Quality of Life in Older Patients With Multiple Myeloma

Multiple Myeloma

United States
ANRS, Emerging Infectious Diseases
Programme PAC-CI; Centre Population et Développement (CEPED/IRD)

Recruiting

Feasibility and Effectiveness of a Pilot Program of Physical Activity to Improve HIV Related Functional Limitations and Disability in Adults Aged 40 and Older From Côte d'Ivoire (VIRAGE+)

HIV Infections

Côte D'Ivoire
Ataturk University

Recruiting

The Effect of Yoga on Sleep Quality, Fatigue and Physical Activity Level of Multiple Sclerosis

Multiple Sclerosis

Turkey
Ataturk University

Recruiting

the Effect of Reiki Application on Depression, Anxiety and Physical Activity in Patient With Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

Turkey
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC; Genentech, Inc.

Recruiting

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

Esophageal Cancer | Gastric Adenocarcinoma | HER2 Gene Mutation

United States
Peng Zhang

Recruiting

Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

China
Servier Bio-Innovation LLC
Merck Sharp & Dohme LLC; Institut de Recherches Internationales Servier

Not yet recruiting

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

MSI-H/dMMR Gastroesophageal-junction Cancer | MSI-H/dMMR Gastric Cancer
Nordlandssykehuset HF
University Hospital of North Norway; The Royal Norwegian Ministry of Health; Norwegian... and other collaborators

Not yet recruiting

Physical Function, Health and Employment for People With Multiple Sclerosis

Multiple Sclerosis
AbbVie

Recruiting

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-2)

Hepatocellular Carcinoma

United States, Taiwan, Spain

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