Search clinical trials for: Inherited Mutation of TP53 Tumor Suppressor Gene
Total 465731 results
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Masonic Cancer Center, University of MinnesotaRecruitingAcute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditionsUnited States
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Dana-Farber Cancer InstituteEli Lilly and CompanyNot yet recruitingEndometrial Cancer | Recurrent Endometrial Cancer | TP53United States
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The First Affiliated Hospital of Xiamen UniversityShanxi Province Cancer Hospital; Sun Yat-sen University; Jiangsu Provincial People... and other collaboratorsRecruiting
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Tianjin Medical University Cancer Institute and...Not yet recruitingNSCLC | EGFR Activating Mutation | Anlotinib | TP53 | Aumolertinib
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Nanfang Hospital of Southern Medical UniversityPeking University People's Hospital; Sun Yat-Sen Memorial Hospital of Sun Yat-Sen... and other collaboratorsRecruitingAllogeneic Hematopoietic Stem Cell Transplantation | Conditioning | TP53 | Myeloid TumorsChina
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Chinese PLA General HospitalZhejiang UniversityRecruitingLymphoma | Solid Tumor, Adult | EphA2 Overexpression | TP53 R273H | TP53 R175H | TP53 R248Q | TP53 R249SChina
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Zhejiang UniversityRecruitingHematopoietic Stem Cell Transplantation | TP53China
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Abramson Cancer Center of the University of PennsylvaniaChildren's Hospital of PhiladelphiaRecruiting
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PMV Pharmaceuticals, IncMerck Sharp & Dohme LLCRecruitingBreast Cancer | Head and Neck Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Metastatic Cancer | Advanced Solid Tumor | Endometrial Cancer | Metastatic Solid Tumor | Other Cancer | Advanced Malignant Neoplasm | Locally AdvancedUnited States, Spain, Korea, Republic of, Singapore, Australia, France, Germany, Italy, United Kingdom
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Institute of Cancer Research, United KingdomCancer Research UKTerminated
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingNon Small Cell Lung CancerItaly
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Sierra Oncology LLC - a GSK companyCompletedAdvanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)United Kingdom
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Tianjin Medical University Second HospitalJiangsu HengRui Medicine Co., Ltd.Unknown
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Ascentage Pharma Group Inc.RecruitingAcute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | AML | MDS | CMML | High-risk Myelodysplastic SyndromeUnited States
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Sierra Oncology LLC - a GSK companyCompletedAdvanced Solid TumorsSpain, United Kingdom
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Scripps HealthJ. Craig Venter InstituteCompletedLi-Fraumeni Syndrome | Hereditary Cancer Syndromes | TP53 Gene Germline Mutation CarrierUnited States
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National Cancer Institute (NCI)CompletedLi-Fraumeni SyndromeUnited States
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National University Hospital, SingaporeNot yet recruiting
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PMV Pharmaceuticals, IncActive, not recruitingHealthy VolunteersUnited States
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Dana-Farber Cancer InstituteCookies for Kids' Cancer; Aileron Therapeutics, Inc.; TeamConnor Childhood Cancer...CompletedLymphoma | Leukemia | Solid Tumor | Brain TumorUnited States
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Cancer Institute and Hospital, Chinese Academy...UnknownDiffuse Large B-Cell Lymphoma | Sintilimab | TP53 Mutation
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British Columbia Cancer AgencyBC Cancer FoundationCompletedGastrointestinal Stromal Tumors | Colorectal Cancer Metastatic | Advanced Melanoma | Advanced Non-Small Cell Lung Carcinoma | Patients With Diagnosed Malignancies Being Considered for Clinical TrialsCanada
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Neogene Therapeutics, Inc.RecruitingBreast Cancer | Pancreatic Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Colorectal Carcinoma | Other Solid TumorsUnited States
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National Cancer Institute (NCI)RecruitingNeoplasms | Li-Fraumeni Syndrome | Tp53 MutationsUnited States
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Ruijin HospitalShanghai Essight Bio Co.,LtdRecruiting
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Instituto do Cancer do Estado de São PauloCompletedPhenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53 (BREAST-TP53)Breast Cancer | Li-Fraumeni Syndrome | TP53 R337H | Prognosis Breast CancerBrazil
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Institute of Cancer Research, United KingdomCancer Research UK; National Institute for Health Research, United KingdomCompletedLi-Fraumeni SyndromeUnited Kingdom
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Tianjin Medical University Second HospitalUnknown
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Astex Pharmaceuticals, Inc.Active, not recruiting
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Oncology Institute of Southern SwitzerlandActive, not recruitingChronic Lymphocytic LeukemiaItaly, Switzerland
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Aptose Biosciences Inc.Active, not recruitingAcute Myeloid Leukemia | Myelodysplastic SyndromesUnited States
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Fondazione IRCCS Istituto Nazionale dei Tumori,...CompletedLocally Advanced Resectable Oral Cavity Squamous Cell CancerItaly
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Medical University of ViennaRecruiting
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Telios Pharma, Inc.Kartos Therapeutics, Inc.Active, not recruitingAcute Myeloid LeukemiaUnited States, Korea, Republic of, Spain, France, Austria, Australia, Germany, Italy
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Universitätsklinikum Hamburg-EppendorfDeutsche KinderkrebsstiftungActive, not recruitingBrain TumorsGermany, Denmark, United Kingdom, Belgium, Poland, Ireland, Austria, Italy, Czechia, France, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland
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Hellenic Cooperative Oncology GroupCompletedBladder Cancer
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Yogen SaunthararajahCompletedT-cell Lymphoma | Indolent B-cell Lymphoma | Aggressive B-cell Lymphoma | Non-Hodgkin's LymphomasUnited States
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Cancer Institute and Hospital, Chinese Academy...RecruitingEndometrial Carcinoma | Recurrent or Metastatic | TP53 MutationChina
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National University Hospital, SingaporeUnknownSquamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of the LungSingapore
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Fudan UniversityRecruitingNon-small Cell Lung Cancer | Neuroendocrine Carcinoma | Histology TransformationChina
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Novartis PharmaceuticalsActive, not recruitingAcute Myeloid Leukemia (AML) | High-risk Myelodysplastic Syndrome (MDS)Spain, Singapore, Australia, Germany, Italy, Finland, United States
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Haukeland University HospitalActive, not recruitingLocally Advanced Breast Cancer | Metastatic Breast CarcinomaNorway
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Haukeland University HospitalTerminatedColorectal Cancer Metastatic | Colorectal Cancer Stage IV | TP53 Gene MutationNorway
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Charles KunosNational Center for Advancing Translational Sciences (NCATS)CompletedLarge-Cell Neuroendocrine CarcinomaUnited States
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National Heart, Lung, and Blood Institute (NHLBI)CompletedCancer | Muscle Weakness | Skin FibroblastsUnited States
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Dana-Farber Cancer InstituteNational Cancer Institute (NCI); Baylor College of Medicine; City of Hope Medical...RecruitingTP53 Gene Mutation | Li-Fraumeni Syndrome | Hereditary Cancer Syndrome | Mosaicism | Clonal HematopoiesisUnited States
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Peking University People's HospitalRecruitingMyelodysplastic Syndromes | Myeloid LeukemiaChina
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Centre Leon BerardNovartisCompletedColorectal Cancer | Metastatic Cancer | Advanced CancerFrance
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt AlleleUnited States
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Dr Cipto Mangunkusumo General HospitalCompletedColorectal Cancer | APC Gene Mutation | TP53 Gene Mutation | PIK3CA Gene Mutation | KRAS Mutation-Related Tumors | MLH1 Gene MutationIndonesia