Search clinical trials for: Inherited cardiac disease

Total 384550 results

UMC Utrecht
Radboud University Medical Center; University Medical Center Groningen; Amsterdam...

Recruiting

The Electronic Cardiovascular Genetics (eCG) Clinic for Presymptomatic Genetic Counselling (eCG)

Inherited Cardiac Disease

Netherlands
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders (DANNIgene)

Hemophilia A | Hemophilia B | Cystic Fibrosis | Sickle Cell Disease | Muscular Dystrophy, Duchenne | Fragile X Syndrome | Huntington Disease | Myotonic Dystrophy | Autosomal Recessive Polycystic Kidney Disease | Neurofibromatosis-Noonan Syndrome | Muscular Dystrophy, Becker | Invasive PreNatal Diagnosis in a... and other conditions

France
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Golden Jubilee National Hospital
University of Glasgow; Royal Infirmary of Edinburgh; Aberdeen Royal Infirmary; Network...

Not yet recruiting

Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes

Aortic Valve Insufficiency | Marfan Syndrome | Bicuspid Aortic Valve | Aortic Diseases | Aortic Dissection | Aortic Aneurysm, Thoracic | Ehlers-Danlos Syndrome | Aortic Ectasia | Loeys-Dietz Syndrome
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Great Ormond Street Hospital...

Recruiting

Inherited Cardiac cONditions In Kids (ICONIK)

Cardiovascular Diseases | Inherited Cardiac Conditions

United Kingdom
Armgo Pharma, Inc.
Food and Drug Administration (FDA)

Recruiting

Treatment of an Inherited Ventricular Arrhythmia

Catecholaminergic Polymorphic Ventricular Tachycardia Type 1

United States, Netherlands
University of Lausanne

Recruiting

Cardiac Manifestation and Inherited Metabolic Diseases

Metabolism, Inborn Errors

Switzerland
Manchester University NHS Foundation Trust

Recruiting

The Role of Biomarkers in Inherited Cardiac Conditions

Inherited Cardiac Conditions

United Kingdom
China National Center for Cardiovascular Diseases
The First Affiliated Hospital with Nanjing Medical University; General Hospital... and other collaborators

Recruiting

China Inherited Ventricular Arrhythmias Registry

Ventricular Arrythmia

China
Foundation Fighting Blindness

Recruiting

Inherited Retinal Degenerative Disease Registry (MRTR)

Retinitis Pigmentosa | Choroideremia | Usher Syndrome | Batten Disease | Leber Congenital Amaurosis | Goldmann-Favre Syndrome | Kearns-Sayre Syndrome | Retinal Disease | Bardet-Biedl Syndrome | Stargardt Disease | Cone Dystrophy | Retinoschisis | Achromatopsia | Gyrate Atrophy | Eye Diseases Hereditary | Bassen-Kornzweig... and other conditions

United States
Washington University School of Medicine

Recruiting

Immune Disorder HSCT Protocol

Severe Combined Immunodeficiency | Chronic Granulomatous Disease | DiGeorge Syndrome | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | X-linked Lymphoproliferative Syndrome | X-linked Agammaglobulinemia | Chediak-Higashi Syndrome | IPEX | Autoimmune Lymphoproliferative Syndrome | Common Variable... and other conditions

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
University Hospital, Montpellier
Hospices Civils de Lyon; University Hospital, Bordeaux; University Hospital,... and other collaborators

Completed

Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations (QUALIMYORYTHM)

Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Brugada Syndrome | Long QT Syndrome | Arrhythmogenic Right Ventricular Dysplasia | Catecholaminergic Polymorphic Ventricular Tachycardia | Restrictive Cardiomyopathy

France
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Pfizer

Completed

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology (TTRACK)

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Italy, Romania, France, Australia, Austria, Portugal, Slovakia, Slovenia, Spain, United Kingdom
Radboud University Medical Center

Active, not recruiting

Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI (APPOSE)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Transcatheter Aortic Valve Replacement | Hemodynamic Monitoring | Acquired Von Willebrand Disease | Heyde's Syndrome

Netherlands
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias

Hypertrophic Cardiomyopathy (HCM) | Long QT Syndrome (LQTS) | Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) | Inherited Cardiac Arrythmias | Brugada Syndrome (BrS) | Early Repolarization Syndrome (ERS) | Arrhythmogenic Cardiomyopathy (AC, ARVD/C) | Dilated Cardiomyopathy (DCM) | Muscular... and other conditions

United States
Johns Hopkins University
National Human Genome Research Institute (NHGRI)

Enrolling by invitation

Clinical Trial of the Sequence of Cardiovascular Genetic Counseling and Testing (RESEQUENCEGC)

Genetic Counseling | Inherited Cardiac Disease

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
University Hospital, Montpellier
Institut National de la Santé Et de la Recherche Médicale, France

Active, not recruiting

Cardiac Rehabilitation of Children and Adolescent With Long QT Syndrome (RYTHMO'FIT)

Pediatric ALL | Long QT Syndrome | Inherited Cardiac Conduction Disorder | Congenital Long Qt Syndrome

France
Stanford University
Alagille Syndrome Alliance

Enrolling by invitation

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Alagille Syndrome | Acquired Von Willebrand Disease | Pulmonary Artery Stenoses

United States
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Enrolling by invitation

Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank (HiRO)

Sudden Cardiac Arrest | Hypertrophic Cardiomyopathy (HCM) | Sudden Arrhythmic Death Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) | Long QT Syndrome (LQTS) | Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Canada
Population Health Research Institute
Boston Scientific Corporation

Completed

Avoid Transvenous Leads in Appropriate Subjects (ATLAS S-ICD)

Ventricular Arrhythmia

Canada
University Hospital, Montpellier
Paediatric Cardiology and Rehabilitation Unit, St-Pierre Institute

Completed

Physical Activity in Children With Inherited Cardiac Diseases

Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Brugada Syndrome | Long QT Syndrome | Catecholaminergic Polymorphic Ventricular Tachycardia

France
University of Padova

Completed

Factor XIII and Other Biomarkers in ST Segment Elevation Myocardial Infarction (eXIST)

Coronary Microvascular Disease | Factor XIII Deficiency | ST-Elevation Myocardial Infarction | Myocardial Haemorrhage

Italy
Jerry Vockley, MD, PhD
Ultragenyx Pharmaceutical Inc

No longer available

Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism

Barth Syndrome | Mitochondrial Trifunctional Protein Deficiency | Very Long-chain acylCoA Dehydrogenase (VLCAD) Deficiency | Carnitine Palmitoyltransferase Deficiencies (CPT1, CPT2) | Long-chain Hydroxyacyl-CoA Dehydrogenase Deficiency | Glycogen Storage Disorders | Pyruvate Carboxylase Deficiency... and other conditions

United States
Nicklaus Children's Hospital f/k/a Miami Children...

Completed

Human Fibrinogen Concentrate in Pediatric Cardiac Surgery (RiaSTAP)

Afibrinogenemia | Hypofibrinogenemia | Bleeding Disorders

United States
Rennes University Hospital

Completed

Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation (ATECMO)

Severe Cardiac Insufficiency

France
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; National Institute for Health Research, United Kingdom

Suspended

A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition (PISICC)

Cardiomyopathies | Inherited Cardiac Conduction Disorder

United Kingdom
University of Trieste
Pfizer

Unknown

Unmasking the Prevalence of AC in an Unselected Echocardiographic Population (AC-TIVE)

Amyloid Cardiomyopathy

Italy
University of British Columbia
Queen's University; Montreal Heart Institute; Quebec Heart Institute

Completed

Long Term Monitoring for Risk of Sudden Death

Brugada Syndrome | Long QT Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy | Catecholaminergic Polymorphic Ventricular Tachycardia | Inherited Cardiac Arrhythmias

Canada
Duke University
Grifols Biologicals, LLC

Completed

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

ATIII Deficiency

United States
McMaster University
Epitome Pharmaceuticals

Terminated

Randomized Controlled Feasibility Trial of the Fearon Algorithm to Improve Management of Unstable Warfarin

Hypoprothrombinemia

Canada
Assistance Publique - Hôpitaux de Paris
Pitié-Salpêtrière Hospital; Pathology department and forensic Institute, Raymond... and other collaborators

Unknown

Genetic Autopsy and Sudden Death (AGEMOS)

Sudden Death

France
Pontificia Universidad Catolica de Chile
Ferring Pharmaceuticals

Completed

Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressin in Valve-Replacement Surgery

Severe Aortic Stenosis | Acquired Von Willebrand Disease Secondary to Severe Aortic Stenosis | Heye´s Syndrome

Chile
Hospital Universitari Vall d'Hebron Research Institute
Universidad de Murcia

Unknown

"Incidence and Consequences of Disorders of Glycosylation in Patients With Conotruncal and Septal Heart Defects" ((CARDIoG))

Congenital Heart Diseases | Antithrombin III Deficiency | Congenital Disorder of Glycosylation | Conotruncal Defects

Spain
Novartis

Completed

Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload

Myelodysplastic Syndromes | Hemoglobinopathies | Diamond-Blackfan Anemia | Transfusional Iron Overload | Other Inherited or Acquired Anaemia | MPD Syndrome | Other Rare Anaemias

Australia
Instituto Grifols, S.A.

Completed

Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass

Coronary Artery Bypass | Acquired Antithrombin III Deficiency

Italy
National Heart Centre Singapore

Unknown

Biomarkers of Inherited Cardiovascular Conditions

Ischemic Heart Disease | Cardiomyopathy

Singapore
Royal Brompton & Harefield NHS Foundation Trust
Ben Williams Trust

Unknown

Families' Experiences of Paediatric ICC Diagnosis (FEPICCD)

Inherited Cardiac Conditions
Mayo Clinic
rEVO Biologics

Terminated

Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac Surgery

Thrombophilia Due to Acquired Antithrombin III Deficiency

United States
University College, London
Inherited Cardiac Diseases Unit, The Heart Hospital, London

Unknown

Morbidity and Mortality in Patients With Hypertrophic Cardiomyopathy: a CALIBER Study (HCM)

Hypertrophic Cardiomyopathy

United Kingdom
Children's Hospital of Eastern Ontario
Heart and Stroke Foundation of Ontario; Variety Village; City of Toronto Parks...

Completed

Healthy Lifestyles for Children With Complex Heart Problems (ReACH)

Cardiomyopathy | Congenital Heart Defects | Inherited Cardiac Arrhythmias

Canada
Isala
CSL Behring

Completed

Haemocomplettan® P During Elective Complex Cardiac Surgery

Fibrinogen Deficiency in Complex Cardiac Surgery

Netherlands
Nantes University Hospital

Terminated

Molecular Mechanism Identification in Inherited Arrhythmias and Valvulopathies From Induced Pluripotent Stem Cells (Diag-iPS)

Inherited Arrhythmias and Valvulopathies

France
University Hospital, Basel, Switzerland

Completed

Acquired Von Willebrand Syndrome in Severe Aortic Stenosis

Bleeding | Aortic Stenosis | Von Willebrand Disease

Switzerland
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Education Program for Patients Receiving Oral Anticoagulation

Cardiovascular Disease | Blood Coagulation Disorders, Inherited | Atrial Fibrillation | Venous Thromboses

Brazil
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Screening for Inherited Heart Disease

Heart Disease | Hypertrophic Cardiomyopathy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease

Cardiomyopathy, Hypertrophic, Familial

United States

Search clinical trials for: Inherited cardiac disease

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