Search clinical trials for: Interferon gamma

Total 4605 results

University Hospital, Grenoble

Not yet recruiting

Quantiferon CMV to Identify Treatment Need For Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT) (QUANTIFOT)

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Cytomegalovirus Infections | Lung Transplantation

France
OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
Xijing Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.

Not yet recruiting

Allogeneic Gammadelta T Cells Combined With Interferon-α1b or PD-1 Monoclonal Antibody in Stage III-IV Amenable to Surgical Resection Melanoma

Melanoma
University of Cape Town
University of Cape Town Lung Institute; Leiden University Medical Center; European... and other collaborators

Recruiting

Same Day Diagnosis of Extrapulmonary TB (TB Serositis and TB Meningitis). (Epi-TB)

Tuberculosis, Extrapulmonary

South Africa, Zambia, Zimbabwe
SPP Pharmaclon Ltd.

Recruiting

A Multicenter Clinical Trial of Ingaron in Pulmonary Tuberculosis

Respiratory Tuberculosis

Russian Federation
Dan Zandberg

Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

United States
Hospices Civils de Lyon

Recruiting

Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients (IGNORANT)

Pneumonia, Ventilator-Associated

France
Research Institute of Epidemiology, Microbiology...

Recruiting

Impact of A. Lumbricoides on Pulmonary Aspergillosis Development

Chronic Pulmonary Aspergillosis | COPD Exacerbation Acute | Ascaris Lumbricoides Infection

Uzbekistan
Manchester University NHS Foundation Trust

Not yet recruiting

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS)

Aspergillosis | Chronic Pulmonary Aspergillosis
The Children's Hospital of Zhejiang University...
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Qilu Hospital... and other collaborators

Recruiting

Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis

Cytokine Storm | Hemophagocytic Lymphohistiocytoses

China
SPP Pharmaclon Ltd.

Recruiting

Study on the Use of Interferon Gamma (Ingaron) Injections in Patients With Drug-resistant Pulmonary Tuberculosis

Pulmonary Tuberculosis

Russian Federation
Mayo Clinic

Recruiting

The Role Of Interferon-gamma In Immune Responses To Invasive Candidiasis

Candidiasis | Fungal Infection

United States
Northwestern University
Foundation for Sarcoidosis Research

Recruiting

Immune Response to SARS-CoV-2/COVID-19 Vaccination in Sarcoidosis

SARS-CoV2 Infection | Sarcoidosis | Vaccine Response Impaired

United States
Emory University
The Marcus Foundation; Ossium Health, Inc.

Recruiting

Mechanisms of Interferon Gamma-primed Mesenchymal Stromal Cells (MSCs) for Moderate-to-severe Persistent Asthma

Asthma

United States
Radboud University Medical Center
Horizon 2020 - European Commission

Recruiting

Safety and Efficacy of Interferon-Gamma 1b in Patients With Candidemia

Candidemia

Netherlands, United States, Switzerland, Germany, Romania, Greece
Fakultas Kedokteran Universitas Indonesia

Recruiting

Proportion of Clinical Improvement & Type 1 Interferon (IFN) Score Changes in Idiopathic Uveitis Patients With Interferon Gamma Release Assay (IGRA) Positive

Anti-Tuberculous Drug Reaction | Tuberculous Uveitis | Tuberculosis; Uveitis (Manifestation)

Indonesia
Mari Dallas

Recruiting

Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation

United States
University Hospital, Montpellier

Completed

COMPArison of Screening Strategies for Active TuBerculosis (COMPASS-TB) (COMPASS-TB)

Latent Tuberculosis | Active Tuberculosis

France
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gamma

Opportunistic Infections | Mycobacterium Tuberculosis | Nontuberculous Mycobacteria

Thailand, China, Taiwan
Hacettepe University

Completed

Effects of Gluten-Free Diet on Nutritional Status in Celiac Patients

Celiac Disease

Turkey
National Cancer Institute (NCI)

Active, not recruiting

Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor

Carcinoid Tumor | Neuroendocrine Neoplasm | Colorectal Neuroendocrine Tumor G1 | Gastric Neuroendocrine Tumor G1 | Neuroendocrine Tumor G2

United States
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia

HIV | Tuberculosis

Liberia, United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Affini-T Therapeutics, Inc.

Active, not recruiting

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Other Skin

United States
Swedish Orphan Biovitrum

Completed

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Primary Hemophagocytic Lymphohistiocytosis

Spain, United States, United Kingdom, Germany, Italy, Sweden, Canada, Switzerland
University of Wisconsin, Madison
National Institute of Dental and Craniofacial Research (NIDCR); University...

Suspended

MSC in Patients With Xerostomia Post XRT in Head and Neck Cancer

Xerostomia Following Radiotherapy

United States
Fakultas Kedokteran Universitas Indonesia

Enrolling by invitation

The Effectivity of Anti Tuberculosis Therapy in Idiopathic Uveitis With Positive IGRA

Tuberculous Uveitis

Indonesia
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Topical Interferon Gamma-1b for Central Serous Chorioretinopathy

Macular Disease | Retinal Disease

United States
SPP Pharmaclon Ltd.
North-Western State Medical University named after I.I.Mechnikov

Completed

Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis (MSPB_TB)

RNA Virus Infections | Lentivirus Infections | Tuberculosis, Pulmonary | Human Immunodeficiency Virus | HIV Coinfection | Aids/Hiv Problem

Russian Federation
Centre Hospitalier Universitaire de Nice

Completed

Functional Non Specific Immunity Monitoring After Kidney Transplantation Using an Interferon Gamma Test (QuantiFERON)

Kidney Transplantation

France
Swedish Orphan Biovitrum
PRA Health Sciences; Cromsource; BioMérieux; Q2 Solutions; Cytel Inc.; ABF Pharmaceutical...

Terminated

Study to Investigate the Pharmacokinetics, Pharmacodynamics and Assess the Efficacy and Safety to Support Dose Selection of Emapalumab in Pre-empting Graft Failure in Patients at High Risk After HSCT.

Graft Failure

Canada, Australia, Israel
University of Campinas, Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Paulínia Municipal...

Completed

COVID-19: BCG As Therapeutic Vaccine, Transmission Limitation, and Immunoglobulin Enhancement (BATTLE)

COVID-19 | SARS-CoV 2 | Transmission | BCG | Therapeutic Vaccine

Brazil
Sawa Ito, MD
Horizon Pharma USA, Inc.

Completed

IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantation

Myelodysplastic Syndromes | Myeloid Leukemia | Allogeneic Stem Cell Transplantation

United States
Michael Hoelscher
European and Developing Countries Clinical Trials Partnership (EDCTP)

Active, not recruiting

Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries (ERASE-TB)

Tuberculosis

Tanzania, Mozambique, Zimbabwe
Zagazig University

Completed

Interleukin 4 and Interferon Gamma Predictors of Human Papillomavirus Immunotherapy in Warts

Warts Hand | Wart, Genital

Egypt
National Cancer Institute (NCI)

Completed

Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma

Recurrent Mycosis Fungoides and Sezary Syndrome | Refractory Mycosis Fungoides and Sezary Syndrome | Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7 | Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7 | Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7 | Stage IIIA Mycosis... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
Federal University of Mato Grosso
Stanford University; Oswaldo Cruz Foundation

Withdrawn

BCG Re-vaccination for Primary Tuberculosis Prophylaxis in the Prison Population (PPT-BCG)

Latent Tuberculosis

Brazil
Lundquist Institute for Biomedical Innovation at...
University of Minnesota; Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

ACTIMMUNE in Intermediate Osteopetrosis

Osteopetrosis

United States
King Chulalongkorn Memorial Hospital

Completed

Treatment Outcome Between Mycobacterium Abscessus Infection in Chronic Lung Disease and Acquired Interferon-gamma Autoantibody Syndrome

Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection | Adult-Onset Immunodeficiency With Acquired Anti-Interferon-Gamma Autoantibodies

Thailand
Swedish Orphan Biovitrum
Light Chain Bioscience - Novimmune SA

Terminated

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH

Hemophagocytic Lymphohistiocytoses

United States
Swedish Orphan Biovitrum
Harvard Medical School (HMS and HSDM); Brigham and Women's Hospital

Completed

Evaluation of IFNγ and Inflammatory Mediators in Patients With Hemophagocytic Lymphohistiocytosis

Hemophagocytic Lymphohistiocytoses

United States
Edwin Horwitz
Ossium Health, Inc.

Suspended

Interferon γ-Primed Mesenchymal Stromal Cells as Prophylaxis for Acute Graft v Host Disease

Myelodysplastic Syndromes | Acute Leukemia

United States
Assiut University

Completed

Effect of Interleukin 6 Receptor Antagonists in SARS-CoV-2 Patients

Corona Virus Infection

Egypt
National Cancer Institute (NCI)

Completed

Blood Collection From People With Ovarian Cancer

Ovarian Neoplasms | Ovarian Cancer | Cancer of the Ovary

United States
University College, London
Public Health England

Completed

Predictive Values of Next Generation Interferon Gamma Release Assays for Latent Tuberculosis Infection (NextGen)

Tuberculosis

United Kingdom
H. Lee Moffitt Cancer Center and Research Institute
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer

Breast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | Breast Cancer Female

United States
Paola Mantegani

Active, not recruiting

Evaluation of a CD4/CD8+ Interferon Gamma Release Assay for Monitoring Anti-Tuberculosis Treatment (IGRA/MAT-1)

Tuberculosis

Italy
Swedish Orphan Biovitrum
PRA Health Sciences; BioMérieux; Cytel Inc.

Terminated

A Clinical Study to Investigate Interferon Gamma (IFNɣ) Signature in Patients Post HSCT and in Patients With Impaired HSC Proliferation Pre-transplant

Graft Failure

Italy, Belgium, United Kingdom, France, Germany, Netherlands
Swedish Orphan Biovitrum
Seventh Framework Programme

Completed

A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Hemophagocytic Lymphohistiocytosis

United States, France, Italy, Spain, United Kingdom
Boston Scientific Corporation

Terminated

A Study of Orally Administered BGC20-0134 (Structured Lipid) in Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Relapsing Remitting Multiple Sclerosis

Spain, Germany, Belgium, Poland, France, Russian Federation

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