Search clinical trials for: Interferon-g

Total 153 results

OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
University of Cape Town
University of Cape Town Lung Institute; Leiden University Medical Center; European... and other collaborators

Recruiting

Same Day Diagnosis of Extrapulmonary TB (TB Serositis and TB Meningitis). (Epi-TB)

Tuberculosis, Extrapulmonary

South Africa, Zambia, Zimbabwe
SPP Pharmaclon Ltd.

Recruiting

A Multicenter Clinical Trial of Ingaron in Pulmonary Tuberculosis

Respiratory Tuberculosis

Russian Federation
Hospices Civils de Lyon

Recruiting

Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients (IGNORANT)

Pneumonia, Ventilator-Associated

France
Research Institute of Epidemiology, Microbiology...

Recruiting

Impact of A. Lumbricoides on Pulmonary Aspergillosis Development

Chronic Pulmonary Aspergillosis | COPD Exacerbation Acute | Ascaris Lumbricoides Infection

Uzbekistan
Manchester University NHS Foundation Trust

Not yet recruiting

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS)

Aspergillosis | Chronic Pulmonary Aspergillosis
The Children's Hospital of Zhejiang University...
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Qilu Hospital... and other collaborators

Recruiting

Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis

Cytokine Storm | Hemophagocytic Lymphohistiocytoses

China
SPP Pharmaclon Ltd.

Recruiting

Study on the Use of Interferon Gamma (Ingaron) Injections in Patients With Drug-resistant Pulmonary Tuberculosis

Pulmonary Tuberculosis

Russian Federation
Northwestern University
Foundation for Sarcoidosis Research

Recruiting

Immune Response to SARS-CoV-2/COVID-19 Vaccination in Sarcoidosis

SARS-CoV2 Infection | Sarcoidosis | Vaccine Response Impaired

United States
Emory University
The Marcus Foundation; Ossium Health, Inc.

Recruiting

Mechanisms of Interferon Gamma-primed Mesenchymal Stromal Cells (MSCs) for Moderate-to-severe Persistent Asthma

Asthma

United States
Radboud University Medical Center
Horizon 2020 - European Commission

Recruiting

Safety and Efficacy of Interferon-Gamma 1b in Patients With Candidemia

Candidemia

Netherlands, United States, Switzerland, Germany, Romania, Greece
Mari Dallas

Recruiting

Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation

United States
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gamma

Opportunistic Infections | Mycobacterium Tuberculosis | Nontuberculous Mycobacteria

Thailand, China, Taiwan
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia

HIV | Tuberculosis

Liberia, United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Affini-T Therapeutics, Inc.

Active, not recruiting

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Other Skin

United States
Swedish Orphan Biovitrum

Completed

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Primary Hemophagocytic Lymphohistiocytosis

Spain, United States, United Kingdom, Germany, Italy, Sweden, Canada, Switzerland
University of Wisconsin, Madison
National Institute of Dental and Craniofacial Research (NIDCR); University...

Suspended

MSC in Patients With Xerostomia Post XRT in Head and Neck Cancer

Xerostomia Following Radiotherapy

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Topical Interferon Gamma-1b for Central Serous Chorioretinopathy

Macular Disease | Retinal Disease

United States
SPP Pharmaclon Ltd.
North-Western State Medical University named after I.I.Mechnikov

Completed

Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis (MSPB_TB)

RNA Virus Infections | Lentivirus Infections | Tuberculosis, Pulmonary | Human Immunodeficiency Virus | HIV Coinfection | Aids/Hiv Problem

Russian Federation
University of Pittsburgh

Active, not recruiting

Immune Interactions in Severe Asthma

Asthma

United States
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Center...

Enrolling by invitation

Comparing Immune Activation and Latent HIV Reservoir Size Between People Living With HIV on Tenofovir-containing Versus NRTI-free ART

Inflammation | HIV | HIV-1-infection | HIV Disease Progression

United States
Sawa Ito, MD
Horizon Pharma USA, Inc.

Completed

IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantation

Myelodysplastic Syndromes | Myeloid Leukemia | Allogeneic Stem Cell Transplantation

United States
Michael Hoelscher
European and Developing Countries Clinical Trials Partnership (EDCTP)

Active, not recruiting

Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries (ERASE-TB)

Tuberculosis

Tanzania, Mozambique, Zimbabwe
National Cancer Institute (NCI)

Completed

Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma

Recurrent Mycosis Fungoides and Sezary Syndrome | Refractory Mycosis Fungoides and Sezary Syndrome | Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7 | Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7 | Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7 | Stage IIIA Mycosis... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
Federal University of Mato Grosso
Stanford University; Oswaldo Cruz Foundation

Withdrawn

BCG Re-vaccination for Primary Tuberculosis Prophylaxis in the Prison Population (PPT-BCG)

Latent Tuberculosis

Brazil
Lundquist Institute for Biomedical Innovation at...
University of Minnesota; Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

ACTIMMUNE in Intermediate Osteopetrosis

Osteopetrosis

United States
Edwin Horwitz
Ossium Health, Inc.

Suspended

Interferon γ-Primed Mesenchymal Stromal Cells as Prophylaxis for Acute Graft v Host Disease

Myelodysplastic Syndromes | Acute Leukemia

United States
H. Lee Moffitt Cancer Center and Research Institute
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer

Breast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | Breast Cancer Female

United States
Paola Mantegani

Active, not recruiting

Evaluation of a CD4/CD8+ Interferon Gamma Release Assay for Monitoring Anti-Tuberculosis Treatment (IGRA/MAT-1)

Tuberculosis

Italy
SPP Pharmaclon Ltd.

Completed

Study of Ingaron's Effect on Efficacy and Resistance to Antibiotics in Community-acquired Pneumonia

Community-acquired Pneumonia

Russian Federation
SPP Pharmaclon Ltd.

Completed

Study of the Use of the Drug Ingaron in Patients With COVID-19

COVID-19 Respiratory Infection | Viral Pneumonia

Russian Federation
SPP Pharmaclon Ltd.

Completed

Study of the Use of the Ingaron in Volunteers for the Prevention of COVID-19

COVID-19 Respiratory Infection

Russian Federation
SPP Pharmaclon Ltd.

Completed

Efficiency and Safety of the Drug Ingaron (Interferon-gamma Human Recombinant) in the Treatment of Chronic Prostatitis (ING-HP-1)

Chronic Prostatitis
Swedish Orphan Biovitrum

Completed

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Arthritis, Juvenile | Lymphohistiocytosis, Hemophagocytic | Macrophage Activation Syndrome | Adult Onset Still Disease

United States, Spain, United Kingdom, France, Italy
Nantes University Hospital

Active, not recruiting

Human Recombinant Interferon Gamma-1b for the Prevention of Hospital-acquired Pneumonia in Critically Ill Patients: a Double-blind, International, Phase 2, Randomized, Placebo-controlled Trial - the PREV-HAP Study (PREV-HAP)

Critically Ill Patients

France, Spain, Greece
Case Western Reserve University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Interferon-Gamma Release Assays in Tuberculosis (TB) - HIV Co-infected Children

HIV | Tuberculosis

South Africa
SPP Pharmaclon Ltd.

Completed

Study of the Efficacy and Safety of the Drug Ingaron (Interferon-gamma) in the Treatment of Anogenital Warts (ING-HPV-1)

Human Papillomavirus Infection | Anogenital Warts

Russian Federation
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients With AIDS Related Complex

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Injections of Human Recombinant Interferon-gamma in Patients With AIDS Who Have Taken Zidovudine

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

Phase I/II Study of Recombinant Human Interferon-gamma (rIFN-gamma) in HIV-Infected Children

HIV Infections

United States
SPP Pharmaclon Ltd.

Completed

Study of the Use of Nasal IFN-γ in Patients for the Prevention of Acute Respiratory Viral Infections, Icluding COVID-19

COVID-19 Respiratory Infection | Acute Respiratory Disease

Russian Federation
Presage Biosciences
Northwell Health; Oregon Health and Science University; University of Washington and other collaborators

Completed

Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma

Soft Tissue Sarcoma Adult

United States
Wake Forest University Health Sciences

Terminated

Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)

COPD | COPD Exacerbation

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Performance of IGRAs for TB Infection Diagnosis in Elderly (IGRage)

Tuberculosis | Ageing

France
Children's Hospital of Philadelphia
Friedreich's Ataxia Research Alliance; Vidara Therapeutics Research Ltd

Completed

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

Friedreich Ataxia

United States
University of Colorado, Denver

Completed

Role of Interferon-gamma 1-b (IFN-γ) on Cells of the Innate Immune System: Functional, Biochemical and Gene Expression Studies in Patients With Chronic Granulomatous Disease

Chronic Granulomatous Disease

United States
Indiana University
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Use of ACTIMMUNE in Patients With ADO2

Autosomal Dominant Osteopetrosis Type 2

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cytokine Gene Polymorphisms in Bone Marrow Failure

Bone Marrow Diseases

United States
Hellenic Institute for the Study of Sepsis

Completed

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis (PROVIDE)

Sepsis | Macrophage Activation Syndrome

Greece

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