Search clinical trials for: JAK inhibitor

Total 84343 results

HALEON

Not yet recruiting

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

Pain
Pfizer

Not yet recruiting

Abrocitinib Taiwan Treatment Pattern and Real World Study in ATopiC Dermatitis (ATTRACT Registry) (ATTRACT)

Skin Diseases | Immune System Diseases | Dermatitis | Eczema | Dermatitis, Atopic | Janus Kinase Inhibitors
International Research Training Group 2804
German Research Foundation; Uppsala University; University Hospital Tuebingen

Not yet recruiting

Breast Cancer & Antiestrogenic Therapy & Brain

Menopause | Breast Cancer Female | Healthy Female | Anti-estrogenic Therapy

Germany
M.D. Anderson Cancer Center
Incyte Corporation

Not yet recruiting

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

Myelofibrosis | Splenomegaly

United States
Ajax Therapeutics, Inc.

Not yet recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | PMF | Post-Essential Thrombocythemia Myelofibrosis | PPV-MF | PET-MF

United States
The Fourth Affiliated Hospital of Zhejiang University...

Not yet recruiting

Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy

Postoperative Analgesia
National Cancer Institute (NCI)

Not yet recruiting

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Myelodysplastic Syndromes

United States
Janssen Cilag S.A.S.

Not yet recruiting

Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia (QOLIBRI)

Leukemia, Lymphocytic, Chronic, B-Cell
General Hospital of Ningxia Medical University

Recruiting

The Effect of Esketamine on Postoperative Pain Relief in Patients Undergoing Laparoscopic Surgery

Postoperative Pain

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis

Rheumatoid Arthritis
Universiteit Antwerpen
McGill University; Aragon Institute of Health Sciences

Not yet recruiting

Comparative Study of the Mechanism of Action of Dry Needling and Botulinum Toxin Type A as a Treatment for Lower Limb Post-stroke Spasticity: a Proof of Concept Controlled Trial (STROKEPOC)

Stroke | Spasticity as Sequela of Stroke
University of Chicago

Not yet recruiting

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation (MPN)

Myeloproliferative Neoplasms

United States
Phramongkutklao College of Medicine and Hospital
Chulalongkorn University; Khon Kaen University; Police General Hospital

Recruiting

Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis

Quality of Life | Knee Osteoarthritis | Pain, Joint | Stiffness of Knee, Not Elsewhere Classified

Thailand
Tanta University

Not yet recruiting

Pentoxifylline as an Adjuvant Therapy in the Treatment of Pediatric Pneumonia; A New Perspective of an Old Drug

Pentoxifylline as an Adjunct Therapy in the Treatment of Pneumonia
Incyte Corporation

Recruiting

Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population (OPERA-1)

Pregnancy Related | Atopic Dermatitis

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care Unit (JAKAHDI)

Hemophagocytic Syndromes
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

United States, Chile, Canada, United Kingdom
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis (TRuE-AD4)

Atopic Dermatitis

Germany, Poland, United States, Spain, United Kingdom, Italy, Belgium, Canada, Netherlands, Australia, Bulgaria, France, Switzerland, Hungary, Korea, Republic of
Sun Yat-sen University
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response

Nasopharyngeal Carcinoma

China
Centro Hospitalar e Universitário de Coimbra, E...

Not yet recruiting

Effects of Resveratrol Supplementation on Oocyte Quality

Infertility | Aging
The University of Texas Health Science Center,...
Baszucki Brain Research Fund

Recruiting

A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression

Bipolar Depression

United States
Fox Chase Cancer Center

Not yet recruiting

Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Essential Thrombocytosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States
Oncotherapeutics
Incyte Corporation

Not yet recruiting

Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma

Multiple Myeloma
Juan LI, MD

Recruiting

To Assess the Efficacy and Safety of Furmonertinib in Patients With Epidermal Growth Factor Receptor 20ins Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Non Small Cell Lung Cancer | EGFR Exon 20 Insertion Mutation

China
Cairo University

Recruiting

Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children

Hand-burned Children

Egypt
University Hospital Tuebingen
Charite University, Berlin, Germany; Robert Bosch Hospital Stuttgart

Not yet recruiting

Exploratory Study Therapeutic Fasting Reduce Physical Limitations, Quality of Life During Aromatase Inhibitor Therapy (FREE-AI)

Breast Cancer Patients Treated With Aromatase Inhibitors

Germany
Peking Union Medical College Hospital

Recruiting

COVID-19 Vaccine Effectiveness Against Recurrent Infection Among Lung Cancer Patients and Biomarker Research

Lung Cancer | Chemotherapy | Antibody | COVID-19 Recurrent | Vaccination | Immune Checkpoint Inhibitor

China
University of California, San Francisco
Incyte Corporation

Not yet recruiting

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

Hemophagocytic Lymphohistiocytoses

United States
University of North Carolina, Chapel Hill
Eli Lilly and Company

Recruiting

Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study

Lichen Planus, Oral | Oral Lichen Planus | Lichen Planus, Mucosal

United States
Wei Gao

Not yet recruiting

Efficacy and Safety of Immunosuppressive Withdrawal After Pediatric Liver Transplantation

Liver Transplant; Complications | Immunosuppression | Immune Tolerance

China
University of Washington
Novartis; Institute for Prostate Cancer Research (IPCR)

Not yet recruiting

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Zhejiang Cancer Hospital

Recruiting

Dalpiciclib Combination With Fulvestrant and Compound Gossyfol Acetate Tablets in Women With CDK4/6 Inhibitor-refractory HR-positive HER-2 Negtive Metastatic Breast Cancer: a Phase 2 Clinical Trial.

Advanced HR-positive and HER2-negative Breast Cancer; CDK4/6 Inhibitor Treatment Failed

China
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Peng Zhang

Recruiting

Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

China
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, Spain, China, Argentina, France
Elpen Pharmaceutical Co. Inc.

Not yet recruiting

TorasEmide Induced Effect on Quality of Life and Clinical parameterS in paTients With chronIc heArt Failure Receiving Eplerenone. (ESTIA)

Chronic Heart Failure
Stephen Ruedrich
Neurocrine Biosciences

Not yet recruiting

Valbenazine Treatment of Tardive Dyskinesia in Adults With Intellectual/Developmental Disabilities (TD-AIDD)

Intellectual Disability | Developmental Disabilities | Tardive Dyskinesia

United States
National Cancer Institute (NCI)

Recruiting

Chemotherapy Combined With Immunotherapy vs Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma

United States
University of Chicago
University of California, Los Angeles; University of Miami; Yale University; National... and other collaborators

Not yet recruiting

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition (HI-SPEED)

Stroke, Acute | Hemorrhagic Stroke | Ischemic Stroke, Acute
Beni-Suef University

Recruiting

Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy

Neuropathy in Cacer Patien

Egypt
National Cancer Institute (NCI)

Not yet recruiting

A Study Using a New Drug, Nivolumab, in Combination With Chemotherapy Drugs to Treat a Type of Cancer Called Nasopharyngeal Carcinoma (NPC)

Stage IV Nasopharyngeal Carcinoma AJCC v8 | Stage II Nasopharyngeal Carcinoma AJCC v8 | Stage III Nasopharyngeal Carcinoma AJCC v8
National Cancer Institute (NCI)

Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Centre Antoine Lacassagne
University of Lyon; University of Firenze and Siena, Napoli, Italy

Recruiting

Individual Food Preferences for the Mediterranean Diet in Cancer Patients (MyPrefMed)

Neoplasms

France
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Extra Alirocumab in Addition to Statin Therapy in Symptomatic IntraCranial Atherosclerotic Stenosis ----a Pilot Study (EAST-sICAS)

Stroke | Intracranial Atherosclerotic Stenosis

China
Astellas Pharma Global Development, Inc.

Recruiting

A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats (OPTION-VMS)

Hot Flashes

United States
Region Örebro County
Helsinki University Central Hospital; Hospital Clinic of Barcelona; University... and other collaborators

Recruiting

Implementing Geriatric Assessment for Dose Optimization of Cyclin-dependent Kinase (CDK) 4/6-inhibitors in Older Breast Cancer Patients (IMPORTANT)

Quality of Life | Advanced Breast Cancer | Metastatic Breast Cancer | Toxicity | Older Patients

Sweden, Finland, Greece, Italy, Norway, Spain
Sun Yat-sen University
First People's Hospital of Foshan; The First Affiliated Hospital, Guangzhou... and other collaborators

Recruiting

Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC (HAIC)

Hepatocellular Carcinoma | Chemotherapy Effect | Chemotherapeutic Toxicity

China
University of Washington
National Cancer Institute (NCI)

Recruiting

Supraphysiological Androgen to Enhance Chemotherapy Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Chiesi Farmaceutici S.p.A.

Recruiting

Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance Therapy (TANGO)

Uncontrolled Asthma

Argentina, Bulgaria, Czechia, Georgia, Germany, Hungary, Italy, Korea, Republic of, Latvia, Lithuania, Poland, Romania, South Africa, Spain
Mayo Clinic

Recruiting

Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors

Estrogen Receptor-Positive Breast Carcinoma

United States

Search clinical trials for: JAK inhibitor

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