Search clinical trials for: Janus Kinase

Total 8735 results

Instituto de Investigación Hospital Universitario...

Recruiting

Optimization of Atopic Dermatitis Treatment That Requires Second-line Systemic Therapy Through Predictive Models

Atopic Dermatitis

Spain
Pfizer

Not yet recruiting

Abrocitinib Taiwan Treatment Pattern and Real World Study in ATopiC Dermatitis (ATTRACT Registry) (ATTRACT)

Skin Diseases | Immune System Diseases | Dermatitis | Eczema | Dermatitis, Atopic | Janus Kinase Inhibitors
AbbVie

Not yet recruiting

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's Disease
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis

Rheumatoid Arthritis
Takeda

Not yet recruiting

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease (VICTRIVA)

Crohn's Disease
Sohag University

Recruiting

Assessment of Serum Levels of Janus Kinase 1 and 2 in Patients With Cholinergic Urticaria

Cholinergic Urticaria

Egypt
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Tofacitinib in Patients With Prurigo Nodularis

Prurigo Nodularis | Itch

China
Hansoh BioMedical R&D Company

Not yet recruiting

Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis

Psoriatic Arthritis
Zhejiang University

Not yet recruiting

Induction and Tapering Therapy With Tofacitinib and Glucocorticoid in Patients With Polymyalgia Rheumatica (ITTGPMR)

Polymyalgia Rheumatica
University of North Carolina, Chapel Hill
Eli Lilly and Company

Recruiting

Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study

Lichen Planus, Oral | Oral Lichen Planus | Lichen Planus, Mucosal

United States
Yanfeng Hou

Recruiting

Efficacy Study of Iguratimod Combined With Tofacitab in Patients With RF Positive/Negative Rheumatoid Arthritis

Rheumatoid Arthritis | Therapy

China
Instituto de Investigación Sanitaria de la Fundación...
Hospital Universitario de Móstoles

Not yet recruiting

Response to Upadacitinib of Enthesitis Evaluated by Ultrasound in Patients With Psoriatic Arthritis

Psoriatic Arthritis

Spain
Peng Zhang

Recruiting

Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

China
Bangabandhu Sheikh Mujib Medical University, Dhaka...
Healthcare Pharmaceuticals

Recruiting

Baricitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Comparison With Tofacitinib

Spondyloarthritis, Axial

Bangladesh
Charite University, Berlin, Germany
Pfizer

Not yet recruiting

ToFAcitinib in Early Active Axial SpondyloarThritis: (FASTLANE)

Axial Spondyloarthritis
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Efficacy and Safety of Vedolizumab Combined With Upadacitinib in Patients With Ulcerative Colitis

Crohn Disease

China
Takeda

Not yet recruiting

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis

United States
Tang-Du Hospital

Not yet recruiting

Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/Contusions

Traumatic Brain Injury

China
Bangabandhu Sheikh Mujib Medical University, Dhaka...
Aristopharma Ltd

Recruiting

Effectiveness of Tofacitinib in Systemic Sclerosis

Efficacy of Tofacitinib in the Systemic Sclerosis

Bangladesh
AstraZeneca

Recruiting

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA (AJAX)

Asthma

Denmark, United States, South Africa, United Kingdom, Argentina, Vietnam, Brazil, Malaysia, Taiwan, France, Germany, Spain, Thailand, Bulgaria, Philippines, Sweden
Hangzhou Highlightll Pharmaceutical Co., Ltd

Recruiting

A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs (TARA)

Rheumatoid Arthritis

China
Tufts Medical Center

Not yet recruiting

Application of N-of-1 Rheumatoid Arthritis

Arthritis, Rheumatoid

United States
Hospital Universitário Professor Edgard Santos
Instituto Gonçalo Muniz FIOCRUZ BA

Not yet recruiting

Tofacitinib Associated With Meglumine Antimoniate in Cutaneous Leishmaniasis (CLTofa23)

Cutaneous Leishmaniasis, American

Brazil
AbbVie

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata (Up-AA)

Alopecia Areata

United States, Australia, Japan, Puerto Rico, New Zealand, China, Canada, Brazil, United Kingdom
Societa Italiana di Dermatologia Medica, Chirurgica...

Recruiting

Real-world Experience on the Use of Upadacitinib in the Treatment of Moderate-severe Adult Atopic Dermatitis (ERUDA) (ERUDA)

Atopic Dermatitis

Italy
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Taiwan, Austria, Italy, Hungary, Bulgaria, Israel, Croatia, Netherlands, Switzerland, Germany, Portugal, Slovakia, France, United Kingdom, Czechi... and more
Berinstein, Jeffrey

Recruiting

A Trial for Acute Severe Ulcerative Colitis

Ulcerative Colitis Acute

United States
Sohag University

Recruiting

Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata

Alopecia Areata

Egypt
AbbVie

Recruiting

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus (SELECT-SLE)

Systemic Lupus Erythematosus

United States, Japan, Puerto Rico, Switzerland, Israel, Korea, Republic of, Hungary, New Zealand, Bulgaria, Latvia, Spain, Taiwan, Slovakia, Croatia, South Africa, Australia, Poland, Portugal, Estonia, France, Lithuania, Brazil, Ger... and more
Jiangsu vcare pharmaceutical technology co., LTD

Recruiting

Efficacy and Safety Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.

Active Ankylosing Spondylitis

China
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis (SELECT- SWITCH)

Rheumatoid Arthritis

United States, Japan, United Kingdom, Canada, Korea, Republic of, Puerto Rico, South Africa, Hungary, Bulgaria, Spain, Portugal, Chile, Croatia, France, Belgium, Germany, Greece, Romania, Brazil, Italy, Serbia, China, Colombia
AbbVie

Recruiting

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Ulcerative Colitis

United States, Japan, Taiwan, Spain, Korea, Republic of, Bulgaria, Hungary, Italy, Poland, France, United Kingdom, Greece, New Zealand, Australia, Belgium, Israel
Pfizer

Not yet recruiting

Korea Xeljanz Post-marketing Surveillance for Juvenile Idiopathic Arthritis (KRXeljanzJIA)

Polyarticular Juvenile Idiopathic Arthritis | Psoriatic Arthritis, Juvenile

Korea, Republic of
National Institute of Diabetes and Digestive and...
Pfizer

Recruiting

Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)

Diabetes Mellitus, Type 1

United States
Yale University
Pfizer

Recruiting

Janus Kinase Inhibition in Sarcoidosis

Sarcoidosis

United States
Fundación Academia Española de Dermatología

Recruiting

Spanish Academy of Dermatology and Venereology Registry of Atopic Dermatitis Therapy (BIOBADATOP)

Dermatitis, Atopic

Spain
University of Colorado, Denver
Children's Hospital Los Angeles

Recruiting

Therapies for Down Syndrome Regression Disorder

Down Syndrome | Regression

United States
AbbVie

Recruiting

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis. (SELECT-sJIA)

Juvenile Idiopathic Arthritis

United States, Japan, Turkey, Australia, China, Spain, Italy
John Reneau

Recruiting

Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia

T-Cell Large Granular Lymphocyte Leukemia

United States
Sohag University

Not yet recruiting

Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheumatoid Arthritis

Rheumatoid Arthritis
Second Affiliated Hospital, School of Medicine,...

Recruiting

Immunoclassification of Psoriasis: a Strategy for Precision Medicine

Psoriasis | Immunoclassification

China
Leiden University Medical Center
Galapagos NV

Not yet recruiting

Januse Kinase Inhibition With Filgotinib to Silence Autoreactive B Cells in Rheumatoid Arthritis (JAKAR)

Rheumatoid Arthritis

Netherlands
Leiden University Medical Center
Galapagos NV

Recruiting

JAK Inhibition in Ulcerative Colitis

Colitis, Ulcerative

Netherlands
Zhejiang Provincial People's Hospital

Recruiting

Efficacy and Safety of Abatacept Combined With JAK Inhibitor for Refractory Rheumatoid Arthritis

Rheumatoid Arthritis | Treatment Compliance | Abatacept

China
Peking University People's Hospital

Recruiting

Clinical Characteristics and Mechanism Research of Inhibitors of Janus Kinase in the Idiopathic Inflammatory Myopathies

Idiopathic Inflammatory Myopathies

China
University of Texas Southwestern Medical Center
Pfizer

Recruiting

Tofacitinib in Recurrent GBM Patients

Glioblastoma

United States
Fundación de Investigación Biomédica - Hospital...

Recruiting

Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events

Ulcerative Colitis | Thromboembolism

Spain
Marie Hudson, MD
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Recruiting

Stand UP to Rheumatoid Arthritis (SUPRA) (SUPRA)

Rheumatoid Arthritis

Canada
Duke University
Eli Lilly and Company; National Institute on Minority Health and Health Disparities...

Recruiting

Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease (JUSTICE)

Chronic Kidney Diseases

United States
Ottawa Hospital Research Institute
The Ottawa Hospital; University of Ottawa

Not yet recruiting

Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patients Receiving JAK-inhibitor vs. TNF-inhibitor Therapy for Active Rheumatoid Arthritis: A Feasibility Study.

Rheumatoid Arthritis

Search clinical trials for: Janus Kinase

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